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Dataset results
59 results for “clinical indicators”
Multidisciplinary Dissection of Renal and Metabolic Effects of Glyfozines on Elderly Patients: From Molecular Aspects to Clinical Indications
ClinicalTrials.gov study NCT07119424. IPD Sharing: UNDECIDED. Countries: 1. Publications: 0.
Clinical Investigation Measuring the Long Term Clinical Performance and Safety of Biodentine™ XP in Patients Treated for Coronal Restorative or Endodontic Dental Indications.
ClinicalTrials.gov study NCT06955429. IPD Sharing: UNDECIDED. Countries: 1. Publications: 0.
Mechanisms of Retinal Revascularization and Clinical Indicators of Neovascular AMD Relapse
ClinicalTrials.gov study NCT05211804. IPD Sharing: UNDECIDED. Countries: 1. Publications: 0.
Observational, Prospective Clinical Study to Evaluate Biomarkers as Indicators of Acute Bacterial or Viral Infections
ClinicalTrials.gov study NCT01917461. IPD Sharing: NO. Countries: 1. Publications: 0.
Indications and Interest of US-guided Synovial Biopsies Performed in Clinical Practice
ClinicalTrials.gov study NCT03417167. IPD Sharing: Not stated. Countries: 1. Publications: 0.
The Study Collect Clinical Data From the Treatment of Liver Cancer With New Drugs After 2019 and Integrate Biochemical and Pathological Indicators to Analyze Prognostic Outcomes, Including Overall Sur
ClinicalTrials.gov study NCT07233759. IPD Sharing: UNDECIDED. Countries: 1. Publications: 0.
COMPARATIVE EVALUATION OF DIRECT PULP CAPPING AND COMPLETE PULPOTOMY IN MATURE PERMANENT MANDIBULAR MOLARS WITH CLINICAL SIGNS INDICATIVE OF MODERATE PULPITIS
ClinicalTrials.gov study NCT06447753. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Economic and Clinical Benefit of Remote Monitoring Among Defibrillator Patients by Indication Subgroups (BENEFIT-RM)
ClinicalTrials.gov study NCT05106062. IPD Sharing: NO. Countries: 1. Publications: 0.
Correlation of Different Ultrasonographic Indices With Clinical Parameters in Carpal Tunnel Syndrome
ClinicalTrials.gov study NCT06115187. IPD Sharing: NO. Countries: 1. Publications: 0.
Transcriptional regulation loss disturbs the brain function and indicates detrimental clinical outcomes of Alzheimer's disease
GEO Series GSE129041. Homo sapiens. 47 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
A Nomogram for Predicting the Diagnosis of Central Malignant Tumors Based on Preoperative Clinical Characteristics and Laboratory Indicators:
ClinicalTrials.gov study NCT06914700. IPD Sharing: Not stated. Countries: 0. Publications: 0.
The Clinical and Radiographic Outcomes of a 3D-printed Patient-specific Biomimetic Bone Substitute in Maxillofacial Indications: an Interventional, Multi-centred, Open-label, Post-market Clinical Inve
ClinicalTrials.gov study NCT04773847. IPD Sharing: YES. Countries: 0. Publications: 0.
Sensitivity and Specificity of Leucocytes Subpopulation Versus Platelet Indices in Prediction of Clinical Outcome for Candidates With Sepsis. A Bi-centric Observational Clinical Trial
ClinicalTrials.gov study NCT06612307. IPD Sharing: Not stated. Countries: 0. Publications: 0.
Characterization of a Candida albicans Isolated from a recurrent Cervical Lymphadenitis Patient and it’s Clinic Indication
GEO Series GSE110291. Candida albicans. 2 samples. Type: Expression profiling by high throughput sequencing.
Safety and efficacy of Interferon y in Friedreich ataxia, using clinical and paraclinical indicators of disease
<p>The data shared in the Zenodo repository include clinical and instrumental data from a randomized clinical trial open label phase II in Friedreich's Ataxia patients that underwent a 6 months treatment with interferone gamma and 6 months follow-up. Permission to use the data will be given only on direct request, correspondence to Prof. Andrea Martinuzzi ( andrea.martinuzzi@lanostrafamiglia.it ).</p>
Clinical performance indicators for monitoring the management of cutaneous melanoma: a population-based perspective
<p>The prognosis of cutaneous malignant melanoma (CMM) is based on disease progression. The highly heterogeneous clinical-pathological characteristics of CMM necessitate standardized diagnostic and therapeutic interventions tailored to cancer's stage. This study utilizes clinical performance indicators to assess the quality of CMM care in Veneto (Northeast Italy). This population-based study focuses on all incidences of CMMs registered by the Veneto Cancer Registry in 2015 (1279 patients) and 2017 (1368 patients). An interdisciplinary panel of experts formulated a set of quality-monitoring indicators for diagnostic, therapeutic, and end-of-life clinical interventions for CMM. The quality of clinical care for patients was assessed by comparing the reference thresholds established by experts to the actual values obtained in clinical practice. The prevalence of stage I-CMM decreased significantly from 2015 to 2017 (from 71.8 to 62.4%; P < 0.001), and almost all the pathology reports mentioned the number of nodes dissected during a lymphadenectomy. More than 90% of advanced CMMs were promptly tested for molecular BRAF status, but the proportion of patients given targeted therapies fell short of the desired threshold (61.1%). The proportion of stage I-IIA CMM patients who inappropriately underwent computerized tomography/MRI/PET dropped from 17.4 to 3.3% ( P < 0.001). Less than 2% of patients received medical or surgical anticancer therapies in the month preceding their death. In the investigated regional context, CMM care exhibited both strengths and weaknesses. The evaluated clinical indicators shed essential insight on the clinical procedures requiring corrective action. It is crucial to monitor clinical care indicators to improve care for cancer patients and promote the sustainability of the healthcare system.</p>
Data set from Ranucci M, Barile L, Ambrogi F, Pistuddi V; Surgical and Clinical Outcome Research (SCORE) Group. Discrimination and calibration properties of the hypotension probability indicator during cardiac and vascular surgery. Minerva Anestesiol. 2019 Jul;85(7):724-730. doi: 10.23736/S0375-9393.18.12620-4. Epub 2018 Nov 22. PMID: 30481996.
<p>Data set from Ranucci M, Barile L, Ambrogi F, Pistuddi V; Surgical and Clinical Outcome Research (SCORE) Group. Discrimination and calibration properties of the hypotension probability indicator during cardiac and vascular surgery. Minerva Anestesiol. 2019 Jul;85(7):724-730. doi: 10.23736/S0375-9393.18.12620-4. Epub 2018 Nov 22. PMID: 30481996.</p> <p> </p> <p>This is the abstract:</p> <p><strong>Background: </strong> Hypotension during surgery is linked to postoperative complications. Recently, a new hemodynamic algorithm intended to predict hypotensive events (hypotension probability indicator [HPI]) has been developed. The aim of the present study is to test the discrimination and calibration properties of the HPI.</p> <p><strong>Methods: </strong> The intraoperative files of 23 patients undergoing cardiac and major vascular surgery receiving the HPI-based hemodynamic monitoring were retrospectively investigated for prediction of hypotensive events (mean arterial pressure <65 mmHg). The HPI was available at 20 seconds intervals; the values of HPI five to seven minutes before a hypotensive event (HPI5-7) were tested for discrimination and calibration.</p> <p><strong>Results: </strong> The HPI5-7 has a fair level of discrimination (area under the curve 0.768) and a poor calibration, due to overestimation of the hypotensive risk. At the observed prevalence, a cut-off value of 85% carries a sensitivity of 62.4% and a specificity of 77.7%, a negative predictive value (NPV) of 97.8% and a positive predictive value (PPV) of 12.6%; a value of 98% has a PPV of 64% and an NPV of 95.3%.</p> <p><strong>Conclusions: </strong> The HPI5-7 may offer some useful insights. Values ≤85% carry a clinically acceptable NPV for hypotensive events at the observed prevalence and may represent a "safe zone" during surgery. Values >85% do not carry enough PPV to trigger hemodynamic interventions, but represent a warning signal. Values >98% are highly suggesting a hypotensive event after 5-7 minutes. Further studies exploring the predictive ability of the HPI at different times are needed.</p>
Data set from Ranucci M, Barile L, Ambrogi F, Pistuddi V; Surgical and Clinical Outcome Research (SCORE) Group. Discrimination and calibration properties of the hypotension probability indicator during cardiac and vascular surgery. Minerva Anestesiol. 2019 Jul;85(7):724-730. doi: 10.23736/S0375-9393.18.12620-4. Epub 2018 Nov 22. PMID: 30481996.
<p>Data set from Ranucci M, Barile L, Ambrogi F, Pistuddi V; Surgical and Clinical Outcome Research (SCORE) Group. Discrimination and calibration properties of the hypotension probability indicator during cardiac and vascular surgery. Minerva Anestesiol. 2019 Jul;85(7):724-730. doi: 10.23736/S0375-9393.18.12620-4. Epub 2018 Nov 22. PMID: 30481996.</p> <p> </p> <p>This is the abstract:</p> <p><strong>Background: </strong> Hypotension during surgery is linked to postoperative complications. Recently, a new hemodynamic algorithm intended to predict hypotensive events (hypotension probability indicator [HPI]) has been developed. The aim of the present study is to test the discrimination and calibration properties of the HPI.</p> <p><strong>Methods: </strong> The intraoperative files of 23 patients undergoing cardiac and major vascular surgery receiving the HPI-based hemodynamic monitoring were retrospectively investigated for prediction of hypotensive events (mean arterial pressure <65 mmHg). The HPI was available at 20 seconds intervals; the values of HPI five to seven minutes before a hypotensive event (HPI5-7) were tested for discrimination and calibration.</p> <p><strong>Results: </strong> The HPI5-7 has a fair level of discrimination (area under the curve 0.768) and a poor calibration, due to overestimation of the hypotensive risk. At the observed prevalence, a cut-off value of 85% carries a sensitivity of 62.4% and a specificity of 77.7%, a negative predictive value (NPV) of 97.8% and a positive predictive value (PPV) of 12.6%; a value of 98% has a PPV of 64% and an NPV of 95.3%.</p> <p><strong>Conclusions: </strong> The HPI5-7 may offer some useful insights. Values ≤85% carry a clinically acceptable NPV for hypotensive events at the observed prevalence and may represent a "safe zone" during surgery. Values >85% do not carry enough PPV to trigger hemodynamic interventions, but represent a warning signal. Values >98% are highly suggesting a hypotensive event after 5-7 minutes. Further studies exploring the predictive ability of the HPI at different times are needed.</p>
Clinical indications for image-guided interventional procedures in the musculoskeletal system, lower limb
<p>Data set from Clinical indications for image-guided interventional procedures in the musculoskeletal system, lower limb: a Delphi-based consensus paper from the European Society of Musculoskeletal Radiology (ESSR)</p>
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Allen Brain Atlas
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International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.