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281 results for “controlled conditions”
Daily variation and repeatability of advertisement calls in an austral temperate forest frog under controlled conditions
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Controlling rheology via boundary conditions in dense granular flows
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Re-assessment of the climatic controls on the carbon and water fluxes of a boreal aspen forest over 1996-2016: changing sensitivity to long-term climatic conditions
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Data and code from: Controlled hyperthermia by flying-foxes in the wild: Understanding mammalian tolerance to hotter summer conditions
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Effects of behavioural types on the problem-solving performance of wild house mice under controlled and semi-natural conditions
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Data from: Management inputs, site conditions, and fire history shape outcomes of invasive plant control and native recovery
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Electrophysiology of neurons adjacent and away from microglia in control and TBI conditions
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Combining transinfected Wolbachia and a genetic sexing strain to control Aedes albopictus in laboratory-controlled conditions
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Dateset The "blue eyed" in our school – overcoming stereotypes as the pathway to creating better conditions for pupil development in the school class - control group and equal socioeconomic status groups
<p>Dateset The “blue eyed” in our school – overcoming stereotypes as the pathway to creating better conditions for pupil development in the school class - control group and equal socioeconomic status groups</p>
Data from: Physiological conditions and genetic controls of phaeomelanin pigmentation in nestling barn swallows
Phaeomelanin is a common pigment that confers a reddish color to animals. Since phaeomelanogenesis requires the sulfhydryl group from cysteine or glutathione (GSH), which is an important antioxidant, this pigmentation and the associated coloration may be an honest signal, whereby only high-quality individuals (e.g., with lower oxidative stress) are able to develop showy plumage. The present study tested the mechanisms underlying the honest signal hypothesis using nestling barn swallows, Hirundo rustica gutturalis, which exhibit phaeomelanic throat plumage patches. We examined the relationship between phaeomelanin pigmentation levels and physiological condition during trait development, and the expression of the phaeomelanin-related gene agouti-signaling protein (ASIP) and the GSH-related gene glutathione S-transferase (GST) in throat feather follicles. We found that during phaeomelanogenesis, heavier nestlings produced more pigmented feathers, indicating that nestlings with high phaeomelanin concentrations are in better condition. We also found that phaeomelanin concentration was negatively correlated with total GSH level, but not significantly related with measures of oxidative stress. Among the GST genes, GSTM3 exhibited the highest expression in the developing feathers during phaeomelanogenesis. The expression levels of ASIP were positively associated with the amount of phaeomelanin deposition and negatively associated with the expression of GSTM3, reducing the amount of GSH that was available as an antioxidant. These findings suggest that high-quality individuals produce high concentrations of phaeomelanin in their plumage without experiencing increased oxidative stress, despite phaeomelanin production, which is triggered by ASIP, potentially actively consuming the sulfhydryl group from GSH.
Single-center, double-blind, randomized, placebo-controlled, single andmultiple dose escalation study to assess safety and tolerability and pharmacokinetics of HRX215 in healthy male volunteers under food and fasting conditions
<p><a name="_Hlk123284665"></a><a name="_Hlk135557103"></a><span><span>Diminished hepatocyte regeneration is a key feature of acute and chronic liver diseases and after extended liver resections, resulting in the inability to maintain or restore a sufficient functional liver mass. </span></span><span><span>Therapies to restore hepatocyte regeneration are lacking, making liver transplantation the only curative option for end stage liver disease. We here report on the structure-based development and characterization (NMR-spectroscopy) of first-in-class small molecule inhibitors of the dual specific kinase MKK4 (MKK4i). MKK4i increased liver regeneration upon hepatectomy in murine and porcine models, allowed for survival of pigs in a lethal 85% hepatectomy model and showed antisteatotic and antifibrotic effects in liver disease mouse models. A first-in-human phase I trial (EudraCT 2021-000193-28) with the clinical candidate HRX215 was conducted and revealed excellent safety and pharmacokinetics. Clinical trials to probe HRX215 for prevention/treatment of liver failure after extensive oncological liver resections or after transplantation of small grafts are warranted.</span></span></p>
DatabaseNH3 : EOM ammonia emission factor measured with INRAE Caract'Air device (under controlled conditions)
<p>This dataset includes ammonia volatilization measurements led by ECOSYS INRAE with Caract’Air device. Ammonia measurements, based on the principle of a mass balance in dynamic chambers are performed under thoroughly controlled and replicative conditions. Caract’Air was designed to be as close as possible to field conditions (in situ soil cores) while optimizing ambient conditions (temperature, air humidity and soil water content) and exchange conditions (flow rate, head volume, air circulation conditions) (Génermont et al., 2021; Décuq et al., 2023). A variety of EOMs are represented ranging from historic livestock effluents and manure to emerging biowastes produced by human urban and agro-industrial activities, all these biowastes having undergone a variety of treatments: raw, separated, composted, anaerobically stored slurries, farm yard manure, sewage sludges, municipal and domestic wastes; various digestats from mechanization; urine based fertilizers; etc. The types and origins of the EOM are reported. The physico-chemical properties of the EOM as well as soils on which the EOM were applied are detailed, leading to 20 and 30 parameters accompanied by information on analytical methods. Measurement conditions are also described including the application dose, the experimental set duration, the ambient conditions, and also the reproductibily conditions, etc. Finally, ammonia volatilization data are compiled, in terms of total cumulative loss (kg N/ha) or volatilization rates (% N and % N-NH4 applied).</p>
Assessing the performance and efficiency of environmental DNA/RNA capture methodologies under controlled experimental conditions
<p>Growing interest and affordability of environmental DNA and RNA (eDNA and eRNA) approaches for biodiversity assessments and monitoring of complex ecosystems have led to the emergence of manifold protocols for nucleic acids (NAs) isolation and processing. Although there is no consensus on a standardized workflow, the common practice for water samples is to concentrate NAs via filtration using varying pore size membranes. Using the smallest pore is assumed to be most efficient for NAs capture from a wide range of material (including sub-cellular particles), however a trade-off must occur between detection of a meaningful molecular signal and cost/time effort when processing samples using fine pore membranes.</p> <p>Comparative studies involving formal efficiency assessments are lacking, which restricts informed decision-making around an optimized sampling approach for applications such as biosurveillance (i.e., detection and monitoring of target taxa - nuisance organisms, endangered and indicator taxa or other species of economic or cultural importance). Here, we present an experimental study using an easily cultured microalgal species (<em>Alexandrium pacificum</em>) to test different filter membranes for capturing NAs in the context of cost/time effort and cell fractions encountered in nature (whole cells, partially lysed, and naked NAs).</p> <p>The results showed no statistically significant difference between membrane types for capturing target eDNA signal from intact and partially lysed cell treatments. In terms of time effort and volume processed, higher efficiency ratings were obtained with the larger pore size (5 µm) cellulose membranes. Positively charged nylon demonstrated enhanced capture of naked NAs, and especially eRNA signal, across treatments.</p> <p>Our findings support using coarse pore size filters for adequate capture of target NA signal (from both eDNA and eRNA) with less processing time. The framework presented here can provide a quick and robust feasibility check and comparative assessment of new and existing NA processing technologies, and allows sufficient control over multiple parameters, including physical-chemical water properties, temporal scales, and concentration and type of input material.</p>
Exploring Conditioning for Generative Music Systems with Human-Interpretable Controls
<p>A sample from the paper 'Exploring Conditioning for Generative Music Systems with Human-Interpretable Controls' conditioned on 1685 Germany.</p>
Exploring Conditioning for Generative Music Systems with Human-Interpretable Controls
<p>Performance RNN is a machine-learning system designed primarily for the generation of solo piano performances using an event-based (rather than audio) representation. More specifically, Performance RNN is a long short-term memory (LSTM) based recurrent neural network that models polyphonic music with expressive timing and dynamics (Oore et al., 2018). The neural network uses a simple language model based on the Musical Instrument Digital Interface (MIDI) file format. Performance RNN is trained on the <em>e-Piano Junior Competition Dataset </em>(International Piano e-Competition 2018), a collection of solo piano performances by expert pianists. As an artistic tool, one of the limitations of the original model has been the lack of useable controls. The standard form of Performance RNN can generate interesting pieces, but little control is provided over <em>what </em>specifically is generated. This paper explores a set of conditioning-based controls used to influence the generation process.</p> <p>Below, a brief description of the samples that accompany the paper are given:</p> <ul> <li><strong>sample_01.mp3: </strong>Composer latitude, longitude, and birth year conditioning. Conditioned on Germany in 1685.</li> <li><strong>sample_02.mp3: </strong>Composer latitude, longitude, and birth year conditioning. Conditioned on Poland in 1810.</li> <li><strong>sample_03.mp3: </strong>Composer latitude, longitude, and birth year conditioning. Conditioned on Poland in 1810.</li> <li><strong>sample_04.mp3: </strong>Tempo keyword conditioning. Conditioned to begin at adagio (very slow) and end at presto (very fast).</li> <li><strong>sample_05.mp3: </strong>Velocity conditioning. Conditioned to begin quiet, grow loud, and then end quietly.</li> <li><strong>sample_06.mp3: </strong>Velocity conditioning. Conditioned to begin quiet, grow loud, and then end quietly.</li> <li><strong>sample_07.mp3: </strong>Relative-position and composer conditioning. Conditioned to be in the style of Debussy and the beginning of a piece.</li> <li><strong>sample_08.mp3: </strong>Relative-position and composer conditioning. Conditioned to be in the style of Bach and the ending of a piece.</li> <li><strong>sample_09.mp3: </strong>Tempo keyword and velocity conditioning. Conditioned to begin slow and quiet and then become fast and loud.</li> <li><strong>sample_10.mp3: </strong>Composer conditioning. Conditioned on Ravel.</li> <li><strong>sample_11.mp3: </strong>Composer conditioning. Conditioned on Schumann.</li> <li><strong>sample_12.mp3: </strong>Velocity conditioning. Conditioned to begin quiet, grow loud, and then end quietly.</li> <li><strong>sample_13.mp3: </strong>Birth year conditioning. Conditioned on the 1600s.</li> <li><strong>sample_14.mp3: </strong>Composer latitude, longitude, and birth year conditioning. Conditioned on Spain in 1860.</li> </ul>
Dataset for "Francisco Cirelli, Dalal Alrajeh, Sebastian Uchitel. Unavoidable Boundary Conditions: A Control Perspective on Goal Conflicts. In Proceedings of the 47th International Conference on Software Engineering 2025."
<p>This is the experimental data for the paper </p> <p>Francisco Cirelli, Dalal Alrajeh, Sebastian Uchitel<br>Unavoidable Boundary Conditions: A Control Perspective on Goal Conflicts. <br>In Proceedings of the 47th International Conference on Software Engineering 2025. </p> <p>We provide various specifications of reactive synthesis control problems taken from various sources. See paper for more details.</p>
Remote Ischaemic Conditioning on Blood Pressure Control in Chronic Kidney Disease Patients
ClinicalTrials.gov study NCT03236350. IPD Sharing: NO. Countries: 1. Publications: 2.
Comparing the Efficacy of the Alcohol Help Centre and Check Your Drinking to a no Intervention Control Condition
ClinicalTrials.gov study NCT02977026. IPD Sharing: NO. Countries: 1. Publications: 2.
Comparing the Efficacy of an Online Gambling Intervention to a no Intervention Control Condition
ClinicalTrials.gov study NCT03124589. IPD Sharing: NO. Countries: 1. Publications: 2.
Comparison of Lethal Means Counseling and an Active Control Condition, With and Without Provision of Gun Locks
ClinicalTrials.gov study NCT03375099. IPD Sharing: NO. Countries: 1. Publications: 1.
ScienceDex guides
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.