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61
datasets available to search
ShareScore release 0.9.0
Dataset results
61 results for “high bleeding risk”
De-escalating Antiplatelet Therapy to Assess Platelet Reactivity and Outcomes in High Bleeding Risk Patients With Recent ACS
ClinicalTrials.gov study NCT05903976. IPD Sharing: UNDECIDED. Countries: 1. Publications: 0.
Prevention of Recurrent Ulcer Bleeding in High-risk Aspirin Users Who Are Not Infected With Helicobacter Pylori
ClinicalTrials.gov study NCT01274767. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Dual Anti-Platelet Optimized Stent for High Bleeding Risk Patient
ClinicalTrials.gov study NCT07140133. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Prevention of Recurrent Ulcer Bleeding in High-risk Users of Low-dose Aspirin
ClinicalTrials.gov study NCT01278550. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Ticagrelor Single Antiplatelet Therapy in Patients With High Risk of Bleeding After DCB for Coronary Small Vessel Disease
ClinicalTrials.gov study NCT06088433. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Cerebral Dysfunction in Chronic ITPwith High Risk of Serious Bleeding Excluding Intracranial Hemorrhage.
ClinicalTrials.gov study NCT01764971. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Over-the-scope Clip Versus Through-the-scope Clip for Endoscopic Hemostasis of High Risk Bleeding Peptic Ulcers
ClinicalTrials.gov study NCT03551262. IPD Sharing: NO. Countries: 1. Publications: 0.
High Gastrointestinal Bleed Risk Outcomes in Patients With Non-valvular Atrial Fibrillation (NVAF) in France
ClinicalTrials.gov study NCT05038228. IPD Sharing: NO. Countries: 1. Publications: 0.
Effect of Thrombolysis on 30-day Mortality in Intermediate High Risk Pulmonary Patients With Low Bleeding Risk
ClinicalTrials.gov study NCT07374978. IPD Sharing: UNDECIDED. Countries: 1. Publications: 0.
Drug-Coated Balloon in Patients With High Bleeding Risk
ClinicalTrials.gov study NCT05221931. IPD Sharing: YES. Countries: 1. Publications: 0.
Comparison of Scoring Balloon and Conventional Balloon Predilation Before Drug Coated Balloon for de Novo Lesion in Patients With High Bleeding Risk
ClinicalTrials.gov study NCT03817801. IPD Sharing: NO. Countries: 1. Publications: 0.
Oral Versus IV Proton Pump Inhibitor in High-risk Bleeding Peptic Ulcers After Endoscopic Hemostasis
ClinicalTrials.gov study NCT01182597. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Drug-Coated Balloon Versus Drug-Eluting Stent for Treatment of De-Novo Coronary Lesions in Patients With High Bleeding Risk-2
ClinicalTrials.gov study NCT06742931. IPD Sharing: YES. Countries: 1. Publications: 0.
Standard Therapy and TIPS for Moderate to High-risk Esophageal and Gastric Variceal Bleeding
ClinicalTrials.gov study NCT06013670. IPD Sharing: NO. Countries: 1. Publications: 0.
The Effect of Carvedilol VS Endoscopic Therapy in Primary Prophylaxis of High-risk Esophageal Gastric Variceal Bleeding
ClinicalTrials.gov study NCT02695732. IPD Sharing: Not stated. Countries: 1. Publications: 0.
AProtinin Versus Tranexamic Acid in Cardiac Surgery Patients With High-risk for Excessive Bleeding
ClinicalTrials.gov study NCT04804345. IPD Sharing: NO. Countries: 1. Publications: 0.
Compression Device to Reduce Pocket Hematoma After Cardiac Implantable Electronic Device Implantation in a High Bleeding Risk Population
ClinicalTrials.gov study NCT06748573. IPD Sharing: NO. Countries: 1. Publications: 0.
Anticoagulation on Demand After Percutaneous Coronary Intervention in High Bleeding Risk Patients
ClinicalTrials.gov study NCT04151680. IPD Sharing: UNDECIDED. Countries: 1. Publications: 0.
Bivalirudin Versus Heparin During PCI in High Bleeding Risk Patients With Acute Coronary Syndromes
ClinicalTrials.gov study NCT07383155. IPD Sharing: UNDECIDED. Countries: 0. Publications: 0.
Dataset related to article "One-Month Dual Antiplatelet Therapy After Bioresorbable Polymer Everolimus-Eluting Stents in High Bleeding Risk Patients"
<p>This record contains raw data related to article "One-Month Dual Antiplatelet Therapy After Bioresorbable Polymer Everolimus-Eluting Stents in High Bleeding Risk Patients"</p> <p>Abstract:</p> <p>Background It is unknown whether contemporary drug-eluting stents have a similar safety profile in high bleeding risk patients treated with 1-month dual antiplatelet therapy following percutaneous coronary interventions. Methods and Results We performed an interventional, prospective, multicenter, single-arm trial, powered for noninferiority with respect to an objective performance criterion to evaluate the safety of percutaneous coronary interventions with Synergy bioresorbable-polymer everolimus-eluting stent followed by 1-month dual antiplatelet therapy in patients with high bleeding risk. In case of need for an oral anticoagulant, patients received an oral anticoagulant in addition to a P2Y<sub>12</sub> inhibitor for 1 month, followed by an oral anticoagulant only. The primary end point was the composite of cardiac death, myocardial infarction, or definite or probable stent thrombosis at 1-year follow-up. The study was prematurely interrupted because of slow recruitment. From April 2017 to October 2019, 443 patients (age, 74.8±9.2 years; women, 29.1%) at 10 Italian centers were included. The 1-year primary outcome occurred in 4.82% (95% CI, 3.17%-7.31%) of patients, meeting the noninferiority compared with the predefined objective performance criterion of 9.4% and the noninferiority margin of 3.85% (<em>P<sub>noninferiority</sub></em><0.001) notwithstanding the lower-than-expected sample size. The rates of cardiac death, myocardial infarction, and definite or probable stent thrombosis were 1.88% (95% CI, 0.36%-2.50%), 3.42% (95% CI, 2.08%-5.62%), and 0.94% (95% CI, 0.35%-2.49%), respectively. Conclusions Among high bleeding risk patients undergoing percutaneous coronary interventions with the Synergy bioresorbable-polymer everolimus-eluting stent, a 1-month dual antiplatelet therapy regimen is safe, with low rates of ischemic and bleeding events. Registration URL: https://www.clinicaltrials.gov; Unique identifier: <a href="http://clinicaltrials.gov/show/NCT03112707">NCT03112707</a>.</p>
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