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730
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ShareScore release 0.9.0
Dataset results
730 results for “high fat diet”
The Effect of a High-fat vs. High-sugar Diet on Liver Fat Accumulation and Metabolism
ClinicalTrials.gov study NCT03145350. IPD Sharing: YES. Countries: 1. Publications: 1.
Effects of a PUFA-rich Diet on Acute Metabolic and Inflammatory High-Fat Meal Responses
ClinicalTrials.gov study NCT02246933. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Impact of a Short-Term High Fat or Low Fat Diet on Intestinal Genes Expression Involved in the Cholesterol and Fatty Acid Metabolism
ClinicalTrials.gov study NCT01806441. IPD Sharing: Not stated. Countries: 1. Publications: 1.
"ADAPT" The Adaptation to High Fat Diets Extention
ClinicalTrials.gov study NCT00493701. IPD Sharing: Not stated. Countries: 1. Publications: 2.
High Fat Diet: Oxidative and Cardiovascular Effects
ClinicalTrials.gov study NCT00696228. IPD Sharing: Not stated. Countries: 1. Publications: 2.
A Reduced-carbohydrate Diet High in Monounsaturated Fats in Type 2 Diabetes
ClinicalTrials.gov study NCT03068078. IPD Sharing: NO. Countries: 1. Publications: 4.
Independent Effects of High-cholesterol (High-egg) and High-saturated Fat Diets on LDL-cholesterol
ClinicalTrials.gov study NCT05267522. IPD Sharing: NO. Countries: 1. Publications: 2.
Feasibility of a Carbohydrate-restricted, High-fat Diet on Head and Neck Squamous Cell Carcinoma Outcomes
ClinicalTrials.gov study NCT04253808. IPD Sharing: NO. Countries: 1. Publications: 1.
Targeting the Gut-brain Axis to Facilitate Weight Loss in High Fat Diet Consumers
ClinicalTrials.gov study NCT04614233. IPD Sharing: YES. Countries: 1. Publications: 1.
Effect of High Monounsaturated Fat Diet on Glycemic Control and Cardiovascular Risk Factors in Type 2 Diabetes
ClinicalTrials.gov study NCT00622960. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Low-Fat, High-Fiber Diet Compared to a Standard Diet in Treating Patients With Prostate Cancer
ClinicalTrials.gov study NCT00020995. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Impact of a High Saturated Fat Diet on Fasted Systemic and White Adipose Tissue Inflammatory Responses
ClinicalTrials.gov study NCT03569189. IPD Sharing: Not stated. Countries: 1. Publications: 1.
The Effect of a High Protein Diet Versus a Low Fat Diet on Body Weight After Smoking Cessation
ClinicalTrials.gov study NCT01069458. IPD Sharing: UNDECIDED. Countries: 1. Publications: 1.
The Effect of High Fat Diet on the Pharmacokinetics of AD16 Tablets in Healthy Chinese Adult Subjects
ClinicalTrials.gov study NCT05787041. IPD Sharing: Not stated. Countries: 1. Publications: 1.
BIOAVAILABILITY OF Glimepiride/Extended Release Metformin (GLI/METXR): High Fat Diet Study
ClinicalTrials.gov study NCT01437813. IPD Sharing: Not stated. Countries: 1. Publications: 5.
The effect of dietary supplementation with blueberry, cyanidin-3-O-β-glucoside, yoghurt and its peptides on gene expression associated with glucose metabolism in skeletal muscle obtained from a high-fat-high-carbohydrate diet induced obesity model
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Untargeted LC–MS metabolomics reveals an adverse effect of high-fat diet on hepatic metabolism of Oreochromis niloticus
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Data and code from: Multigenerational exposure to high-fat and high-sugar diets exacerbates reproductive distress in an insect model
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Data from: Curcumin improves glycolipid metabolism through regulating peroxisome proliferator activated receptor γ signalling pathway in high-fat diet-induced obese mice and 3T3-L1 adipocytes
Curcumin, an active component derived from the Curcuma longa L. which is a traditional Chinese medicine that is widely used for treating metabolic diseases through regulating different molecular pathway. Here, in this study, we aimed to comprehensively investigate the effects of curcumin on glycolipid metabolism in vivo and in vitro and then determine the underlying mechanism. Male C57BL/6J obese mice and 3T3-L1 adipocytes were used in vivo and in vitro study, respectively. Our results demonstrated that treatment with curcumin for 8 weeks decreased body weight, fat mass and serum lipid profiles. Meanwhile, it lowered fasting blood glucose and increased the insulin sensitivity in high-fat diet induced obese mice. In addition, curcumin stimulated lipolysis and improve glycolipid through upregulating the expressions of ATGL, HSL, PPARγ, C/EBPα and PPARα in adipose tissue of the mice. In differentiated 3T3-L1 cells, curcumin reduced glycerol release and increased glucose uptake via upregulating PPARγ and C/EBPα. We concluded that curcumin has potential to improve glycolipid metabolism disorders caused by obesity through regulating PPARγ signaling pathway.
Data from: High fat diet induces microbiota-dependent silencing of enteroendocrine cells
<p>Enteroendocrine cells (EECs) are specialized sensory cells in the intestinal epithelium that sense and transduce nutrient information. Consumption of dietary fat contributes to metabolic disorders, but EEC adaptations to high fat feeding were unknown. Here, we established a new experimental system to directly investigate EEC activity in vivo using a zebrafish reporter of EEC calcium signaling. Our results reveal that high fat feeding alters EEC morphology and converts them into a nutrient insensitive state that is coupled to endoplasmic reticulum (ER) stress. We called this novel adaptation 'EEC silencing'. Gnotobiotic studies revealed that germ-free zebrafish are resistant to high fat diet induced EEC silencing. High fat feeding altered gut microbiota composition including enrichment of <em>Acinetobacter </em>species, and we identified an <em>Acinetobacter</em> strain sufficient to induce EEC silencing. These results establish a new mechanism by which dietary fat and gut microbiota modulate EEC nutrient sensing and signaling.</p>
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
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DANDI Archive for NWB datasets
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International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
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