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214 results for “immunomodulatory”
Immunomodulatory Effect of Dexmedetomidine as an Adjuvant Drug in Laparoscopic Cholecystectomies
ClinicalTrials.gov study NCT05489900. IPD Sharing: NO. Countries: 1. Publications: 1.
A Phase I Clinical Trial To Evaluate the Toxicity, Antiviral and Immunomodulatory Effects of a Range of Doses of Ampligen in HIV-Infected Subjects
ClinicalTrials.gov study NCT00000713. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Immunomodulatory Therapy in Women With Autoimmune Premature Ovarian Insufficiency
ClinicalTrials.gov study NCT05586737. IPD Sharing: NO. Countries: 1. Publications: 0.
Figure 1 from: Ivankiv YI, Oleshchuk OM (2020) Immunomodulatory effect of melatonin supplementation in experimental diabetes. Pharmacia 67(4): 223-228. https://doi.org/10.3897/pharmacia.67.e55437
Figure 1 Immunoglobulins A, M, G data diversity at different diabetes models with melatonin introduction. DM1 + MT – diabetes mellitus type 1 plus melatonin; DM2 + MT – diabetes mellitus type 2 plus melatonin; Ig A – immunoglobulin A; Ig M – immunoglobulin M; Ig G – immunoglobulin G; g/l – gram per liter.
Antimicrobial, Probiotic, and Immunomodulatory Potential of Cannabis sativa Extract and Delivery Systems
<p>Article, Dataset for the article</p> <p> </p> <h2>Abstract</h2> <div>The compounds present in hemp show multidirectional biological activity. It is related to the presence of secondary metabolites, mainly cannabinoids, terpenes, and flavonoids, and the synergy of their biological activity. The aim of this study was to assess the activity of the Henola <span>Cannabis sativae</span> extract and its combinations with selected carriers (polyvinyl caprolactam–polyvinyl acetate–polyethylene glycol graft copolymer, magnesium aluminometasilicate, and hydroxypropyl-β-cyclodextrin) in terms of antimicrobial, probiotic, and immunobiological effects. As a result of the conducted research, the antimicrobial activity of the extract was confirmed in relation to the following microorganisms: <span>Clostridium difficile</span>, <span>Listeria monocytogenes</span>, <span>Enterococcus faecalis</span>, <span>Staphylococcus aureus</span>, <span>Staphylococcus pyrogenes</span>, <span>Escherichia coli</span>, <span>Klebsiella pneumoniae</span>, <span>Salmonella typhimurium</span>, <span>Pseudomonas aereuginosa</span>, and <span>Candida albicans</span> (microorganism count was reduced from ~10<sup>2</sup> CFU mL<sup>−1</sup> to <10 CFU mL<sup>−1</sup> in most cases). Additionally, for the system with hydroxypropyl-β-cyclodextrin, a significant probiotic potential against bacterial strains was established for strains <span>Lactobacillus acidophilus</span>, <span>Lactobacillus casei</span>, <span>Lactobacillus plantarum</span>, <span>Lactobacillus brevis</span>, <span>Lactobacillus rhamnosus</span>, <span>Lactobacillus reuteri</span>, <span>Pediococcus pentosaceus</span>, <span>Lactococcus lactis</span>, <span>Lactobacillus fermentum</span>, and <span>Streptococcus thermophilus</span> (microorganism count was increased from ~10<sup>2</sup> to 10<sup>4</sup>–10<sup>7</sup>). In terms of immunomodulatory properties, it was determined that the tested extract and the systems caused changes in IL-6, IL-8, and TNF-α levels.</div> <div> <div> <div>Keywords: </div> <a href="https://www.mdpi.com/search?q=Cannabis+sativa"><span>Cannabis sativa</span></a>; <a href="https://www.mdpi.com/search?q=cannabidiol">cannabidiol</a>; <a href="https://www.mdpi.com/search?q=antibacterial">antibacterial</a>; <a href="https://www.mdpi.com/search?q=probiotic">probiotic</a>; <a href="https://www.mdpi.com/search?q=immunomodulatory">immunomodulatory</a>; <a href="https://www.mdpi.com/search?q=immunostimulatory">immunostimulatory</a></div> </div>
Supplementary material 1 from: Indradi RB, Pitaloka DAE, Suryani (2022) Network pharmacology to uncover potential anti-inflammatory and immunomodulatory constituents in Curcuma longa rhizome as complementary treatment in COVID-19. Pharmacia 69(4): 995-1003. https://doi.org/10.3897/pharmacia.69.e89799
Datasets of Network Pharmacology Process
Fig. 6 in Highly oxygenated isoryanodane diterpenoids from the leaves of Cinnamomum cassia and their immunomodulatory activities
Fig. 6. Amplified HSQC spectra of diterpenoids 5 (A) and 6 (B).
Fig. 2. 1H–1H in Highly oxygenated isoryanodane diterpenoids from the leaves of Cinnamomum cassia and their immunomodulatory activities
Fig. 2. 1H–1H COSY, key HMBC, and NOESY correlations of cinnacassin A (1).
Fig. 3. X in Highly oxygenated isoryanodane diterpenoids from the leaves of Cinnamomum cassia and their immunomodulatory activities
Fig. 3. X-ray ORTEP drawing of cinnacassin A (1).
Study of the Safety of Therapeutic Treatment With an Immunomodulatory Agent (N-803) in Adults With COVID-19
ClinicalTrials.gov study NCT04385849. IPD Sharing: NO. Countries: 1. Publications: 0.
Effectiveness and Safety of COVID-19 Vaccine in Patients With IBD Treated With Immunomodulatory or Biological Drugs (ESCAPE-IBD)
ClinicalTrials.gov study NCT04769258. IPD Sharing: Not stated. Countries: 0. Publications: 2.
Immunomodulatory Drugs (Lenalidomide With or Without Pomalidomide) in Combination With a Corticosteroid Drug (Dexamethasone) for the Treatment of Multiple Myeloma
ClinicalTrials.gov study NCT05288062. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Study of the Safety of Therapeutic Tx With Immunomodulatory MSC in Adults With COVID-19 Infection Requiring Mechanical Ventilation
ClinicalTrials.gov study NCT04397796. IPD Sharing: NO. Countries: 1. Publications: 0.
Systemic Immunomodulatory Effects and Pharmacogenetics of Atorvastatin in Early Atherosclerosis
ClinicalTrials.gov study NCT00361283. IPD Sharing: Not stated. Countries: 1. Publications: 0.
B-cell Depletion in Offspring to Women With MS Under Immunomodulatory Treatment
ClinicalTrials.gov study NCT06711354. IPD Sharing: YES. Countries: 0. Publications: 18.
Placebo-controlled, Dose-escalation Study of the Safety of IMO-2125 (Immunomodulatory Oligonucleotide) in Hepatitis C-infected Patients
ClinicalTrials.gov study NCT00728936. IPD Sharing: Not stated. Countries: 2. Publications: 0.
A Multi-Center Study of a SCD for Immunomodulatory Dysregulation in Pediatric AKI
ClinicalTrials.gov study NCT04869787. IPD Sharing: NO. Countries: 1. Publications: 0.
Immunomodulatory Biomimetic Device to Treat Myocardial Stunning in End-stage Renal Disease Patients
ClinicalTrials.gov study NCT03539861. IPD Sharing: Not stated. Countries: 1. Publications: 0.
An Exploratory Study of the Safety and Efficacy of Prophylactic Immunomodulatory Treatment in Myozyme-naive Cross-Reacting Immunologic Material (CRIM[-]) Patients With Infantile-Onset Pompe Disease
ClinicalTrials.gov study NCT00701129. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Data from: The neuroendocrine immunomodulatory axis-like pathway mediated by circulating haemocytes in pacific oyster Crassostrea gigas
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International Brain Laboratory public data
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OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.