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808 results for “inflammatory cells”
Vitamin D Regulation of Gut Specific B Cells and Antibodies Targeting Gut Bacteria in Inflammatory Bowel Disease
ClinicalTrials.gov study NCT04828031. IPD Sharing: Not stated. Countries: 1. Publications: 9.
Study to Determine the Effect of an Anti-IgE Agent on Inflammatory Cells in the Skin of Atopic Dermatitis Patients
ClinicalTrials.gov study NCT00822783. IPD Sharing: Not stated. Countries: 1. Publications: 4.
Raw data relative to: "Distinct Expression of Inflammatory Features in T Helper 17 Cells from Multiple Sclerosis Patients"
<p><strong>Introduction</strong></p> <p> Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system (CNS). T helper (Th) 17 lymphocytes play a role in the pathogenesis of MS. Indeed, Th17 cells are abundant in the cerebrospinal fluid and peripheral blood of MS patients and promote pathogenesis in the mouse model of MS. To gain insight into the function of Th17 cells in MS, we tested whether Th17 cells polarized from naïve CD4 T cells of healthy donors and MS patients display different features</p> <p><strong>Methods</strong></p> <p>We analysed several parameters that typify the Th17 profile during the differentiation process of naïve CD4 T cells obtained from relapsing-remitting (RR)-MS patients and healthy donors (HD), such as expression of surface receptors by flow cytometry.</p> <p><strong>Results</strong></p> <p>The analysis revealed that expression of IL-1R1 is significantly increased in Th17 cells derived from MS patients compared to healthy donor-derived cells. Interestingly, IL-1R1 expression is also increased in Th17 cells circulating in the blood of MS patients compared to healthy donors. Since IL-1R1 play a crucial role in the activation of immune cells, our data indicate that high expression of these molecules in Th17 cells from MS patients could be related to their high inflammatory status.</p>
Unveiling CNS Cell Morphology with Deep Learning: A Gateway to Anti-Inflammatory Compound Screening
<p>Understanding the connection between cellular structure and observable traits is vital for comprehending cell behavior, especially in neuropathological conditions. Current limitations exist in applying advanced image analysis, like deep learning, to central nervous system cells due to challenges such as the need for extensive labeled data, difficulty in detecting subtle changes, and the presence of batch effects. The study focuses on overcoming these issues in the context of neuroinflammation, utilizing a deep learning approach to effectively analyze morphological changes in neuronal and microglial cells. This innovative method aids in studying neuroinflammation, facilitating the screening of potential therapeutic compounds and bridging gaps in neuropathological research and pharmaceutical development.</p>
Antioxidant and anti-inflammatory function of walnut green husk aqueous extract (WNGH-AE) on human hepatocellular carcinoma cells (HepG2) treated with t-BHP
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Botryococcus terribilis Ethanol Extract Exerts An-ti-inflammatory Effects on Murine RAW264 Cells
<p><strong>Supplementary Materials: </strong></p> <p><strong>Figure S1: Downregulated DEGs in BTEE-treated conditions related to ‘cytokine-cytokine receptor interaction’ KEGG pathway; </strong></p> <p><strong>Supplementary file 1: Commonly regulated gene list; </strong></p> <p><strong>Supplementary file 2: PPI network analysis of common downregulated DEGs</strong></p> <p><strong>Supplementary file 3: Kinase coexpression analysis by the downregulated DEGs</strong></p> <p><strong>Supplementary file 4: Drug/chemical perturbation analysis by the downregulated DEGs</strong></p>
Fig. 1 in Glycoglycerolipids from the leaves of Perilla frutescens (L.) Britton (Labiatae) and their anti-inflammatory activities in lipopolysaccharide-stimulated RAW264.7 cells
Fig. 1. The separation procedures of glycoglycerolipids from Perilla frutescens leaves.
Fig. 3 in Sesquiterpene derivatives from the agarwood of Aquilaria malaccensis and their anti-inflammatory effects on NO production of macrophage RAW 264.7 cells
Fig. 3. Selected NOESY correlations of compounds 1–9.
Fig. 4. X in Sesquiterpene derivatives from the agarwood of Aquilaria malaccensis and their anti-inflammatory effects on NO production of macrophage RAW 264.7 cells
Fig. 4. X-ray crystallographic structure of compounds 1 and 4.
Fig. 1 in Sesquiterpene derivatives from the agarwood of Aquilaria malaccensis and their anti-inflammatory effects on NO production of macrophage RAW 264.7 cells
Fig. 1. Chemical structure of compounds 1–9.
Fig. 2. Key HMBC, 1 H–1 H in Sesquiterpene derivatives from the agarwood of Aquilaria malaccensis and their anti-inflammatory effects on NO production of macrophage RAW 264.7 cells
Fig. 2. Key HMBC, 1 H–1 H COSY correlations of compounds 1–9.
Stem Cell Transplantation in Idiopathic Inflammatory Myopathy Diseases
ClinicalTrials.gov study NCT00278564. IPD Sharing: NO. Countries: 1. Publications: 0.
Hyporesponsiveness of Natural Killer Cells and a Dysfunctional Inflammatory Response in Critically Ill Patients
ClinicalTrials.gov study NCT02565589. IPD Sharing: Not stated. Countries: 0. Publications: 1.
Safety and Tolerability Of Allogeneic Mesenchymal Stromal Cells in Pediatric Inflammatory Bowel Disease
ClinicalTrials.gov study NCT02150551. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Significance of MAIT Cells in Inflammatory Bowel Disease
ClinicalTrials.gov study NCT05598346. IPD Sharing: Not stated. Countries: 0. Publications: 26.
FTC/RPV/TDF on T-Cell Activation, CD4+ T-Cell Count, Inflammatory Biomarkers and Viral Reservoir
ClinicalTrials.gov study NCT01777997. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Combination Chemotherapy and Peripheral Blood Stem Cell Transplant Followed By Aldesleukin and Sargramostim in Treating Patients With Inflammatory Stage IIIB or Metastatic Stage IV Breast Cancer
ClinicalTrials.gov study NCT00003199. IPD Sharing: Not stated. Countries: 1. Publications: 0.
ADVAIR DISKUS® (Fluticasone Propionate/Salmeterol) Inhaler Versus SEREVENT DISKUS® (Salmeterol) Inhlaer On Inflammatory Cells And Markers In Chronic Obstructive Pulmonary Disease. ADVAIR DISKUS® and S
ClinicalTrials.gov study NCT00346749. IPD Sharing: YES. Countries: 1. Publications: 0.
Diagnostic Value of C-reactive Protein and White Blood Cell Counts for Early Detection of Inflammatory Complications After Open Resection of Colorectal Cancer
ClinicalTrials.gov study NCT01221324. IPD Sharing: Not stated. Countries: 0. Publications: 1.
Data from: Human blood and mucosal regulatory T cells express activation markers and inhibitory receptors in inflammatory bowel disease
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.