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212
datasets available to search
ShareScore release 0.9.0
Dataset results
212 results for “nicotinamide”
Nicotinamide Supplementation Improves Physical Performance in Older Adults at Risk of Falls
ClinicalTrials.gov study NCT06465602. IPD Sharing: NO. Countries: 1. Publications: 19.
NR-SAFE: Safety of High-dose Nicotinamide Riboside (NR) in Parkinson's Disease
ClinicalTrials.gov study NCT05344404. IPD Sharing: NO. Countries: 1. Publications: 1.
Nicotinamide in the Treatment of Psoriasis
ClinicalTrials.gov study NCT01763424. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Efficacy and Safety of 30% Salicylic Acid and 10% Nicotinamide Combined Therapy in Melasma
ClinicalTrials.gov study NCT07062120. IPD Sharing: NO. Countries: 1. Publications: 7.
Anticancer Activity of Nicotinamide on Lung Cancer
ClinicalTrials.gov study NCT02416739. IPD Sharing: NO. Countries: 1. Publications: 18.
Nicotinamide Riboside Impact on Extracellular Nicotinamide Adenine Dinucleotide (NAD+)
ClinicalTrials.gov study NCT06005350. IPD Sharing: NO. Countries: 1. Publications: 8.
Improved Skin Whitening Outcomes Associated With Nicotinamide Fortified Consumption in 30 to 50- Year-old Women
ClinicalTrials.gov study NCT05696938. IPD Sharing: NO. Countries: 1. Publications: 5.
Open-label Study to Assess Increasing Levels of NAD+(Nicotinamide Adenine Dinucleotide)
ClinicalTrials.gov study NCT03707652. IPD Sharing: NO. Countries: 1. Publications: 13.
Nicotinamide Riboside for Treating Elevated Systolic Blood Pressure and Arterial Stiffness in Middle-aged and Older Adults
ClinicalTrials.gov study NCT03821623. IPD Sharing: NO. Countries: 1. Publications: 3.
Efficacy of Nicotinamide on Retinal Ganglion Cell Functions in Glaucoma Patients
ClinicalTrials.gov study NCT06078605. IPD Sharing: Not stated. Countries: 1. Publications: 1.
LncRNA Nicotinamide Nucleotide Transhydrogenase-Antisense RNA1 NNT-AS1 in CRC
ClinicalTrials.gov study NCT06531902. IPD Sharing: UNDECIDED. Countries: 1. Publications: 1.
Effect of Nicotinamide Riboside on Ketosis, Fat Oxidation & Metabolic Rate
ClinicalTrials.gov study NCT06044935. IPD Sharing: YES. Countries: 1. Publications: 1.
Effect of Nicotinamide Riboside and Pterostilbene Supplementation on Muscle Regeneration in Elderly Humans
ClinicalTrials.gov study NCT03754842. IPD Sharing: UNDECIDED. Countries: 1. Publications: 1.
The Effects of Nicotinamide Adenine Dinucleotide (NAD) on Brain Function and Cognition
ClinicalTrials.gov study NCT02942888. IPD Sharing: NO. Countries: 1. Publications: 1.
Comparison of Nicotinamide Treatments for Actinic Keratosis
ClinicalTrials.gov study NCT07049068. IPD Sharing: YES. Countries: 1. Publications: 4.
Nicotinamide Riboside and Metabolic Health
ClinicalTrials.gov study NCT02835664. IPD Sharing: Not stated. Countries: 1. Publications: 2.
Effects of Nicotinamide in Patients With Chronic Lymphocytic Leukemia With History of Non-melanoma Skin Cancers
ClinicalTrials.gov study NCT04844528. IPD Sharing: NO. Countries: 1. Publications: 15.
Nicotinamide riboside and pterostilbene cooperatively delay motor neuron failure in ALS SOD1G93A mice
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Dataset related to article "Nicotinamide Phosphoribosyltransferase Acts as a Metabolic Gate for Mobilization of Myeloid-Derived Suppressor Cells"
<p>Cancer induces alteration of hematopoiesis to fuel disease progression. We report that in tumor-bearing mice the macrophage colony-stimulating factor elevates the myeloid cell levels of nicotinamide phosphoribosyltransferase (NAMPT), the rate-limiting enzyme in the NAD salvage pathway, which acts as negative regulator of the CXCR4 retention axis of hematopoietic cells in the bone marrow. NAMPT inhibits CXCR4 through a NAD/Sirtuin 1-mediated inactivation of HIF1α-driven <em>CXCR4</em> gene transcription, leading to mobilization of immature myeloid-derived suppressor cells (MDSC) and enhancing their production of suppressive nitric oxide. Pharmacologic inhibition or myeloid-specific ablation of NAMPT prevented MDSC mobilization, reactivated specific antitumor immunity, and enhanced the antitumor activity of immune checkpoint inhibitors. Our findings identify NAMPT as a metabolic gate of MDSC precursor function, providing new opportunities to reverse tumor immunosuppression and to restore clinical efficacy of immunotherapy in patients with cancer. SIGNIFICANCE: These findings identify NAMPT as a metabolic gate of MDSC precursor function, providing new opportunities to reverse tumor immunosuppression and to restore clinical efficacy of immunotherapy in cancer patients.</p>
Nicotinamide Riboside and Mitochondrial Metabolism
ClinicalTrials.gov study NCT03951285. IPD Sharing: UNDECIDED. Countries: 0. Publications: 6.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.