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154
datasets available to search
ShareScore release 0.9.0
Dataset results
154 results for “off-target”
Systematic Identification of CRISPR-mediated Off-target Effects by CROss-seq
GEO Series GSE182568. Homo sapiens. 41 samples. Type: Genome binding/occupancy profiling by high throughput sequencing; Other.
Probing the off-target effect of EGFP siRNA and pro-siRNA in the HeLa-d1EGFP cell line
GEO Series GSE44256. Homo sapiens. 4 samples. Type: Expression profiling by high throughput sequencing.
Ribozyme-enhanced single-stranded Ago2-processed interfering RNA triggers efficient gene silencing with fewer off-target effects.
GEO Series GSE68631. Homo sapiens. 11 samples. Type: Expression profiling by high throughput sequencing; Non-coding RNA profiling by high throughput sequencing.
Genome-wide determination of on-target and off-target characteristics for RNA-guided DNA Methylation by dCas9 methyltransferases (CRISPRme)
GEO Series GSE92311. Homo sapiens. 17 samples. Type: Genome binding/occupancy profiling by high throughput sequencing; Methylation profiling by high throughput sequencing.
CRISPR/Cas9-Mediated PTPRZ1 Knockout Suppresses LUSC Proliferation with Genome-Wide Off-Target Analysis
GEO Series GSE306332. Homo sapiens. 6 samples. Type: Other.
Sensitive and unbiased genome-wide profiling of base-editor-induced off-target activity with CHANGE-seq-BE [Digenome-seq]
GEO Series GSE312238. Homo sapiens. 11 samples. Type: Other.
On-target and Off-target Activities of RAG Are Restricted by Topological Chromatin Domains
GEO Series GSE73007. Mus musculus. 40 samples. Type: Other.
A Cas12a ortholog with stringent PAM recognition followed by low off-target editing rates for genome editing
GEO Series GSE146420. Homo sapiens; synthetic construct. 195 samples. Type: Other.
shRNA-based miRNA overexpression results in significant off-target effects caused by isomiR production [miRNA-seq]
GEO Series GSE241301. Homo sapiens. 10 samples. Type: Non-coding RNA profiling by high throughput sequencing.
Alteration of target cleavage patterns and off-target reduction of antisense oligonucleotides incorporating 2-N-carbamoyl- or (2-pyridyl)guanine [Rluc]
GEO Series GSE228741. Homo sapiens. 12 samples. Type: Expression profiling by array.
Selection of well-tolerated GalNAc-conjugated siRNAs by screening for RNAi-mediated off-target effects in rodent toxicity studies
GEO Series GSE108823. Rattus norvegicus. 36 samples. Type: Expression profiling by high throughput sequencing.
Joint single-cell profiling of Cas9 edits and transcriptomes reveals on- and off-target effects on gene expression (Superb-seq)
GEO Series GSE284207. Homo sapiens. 4 samples. Type: Expression profiling by high throughput sequencing.
CRISPR adenine and cytosine base editors with reduced RNA off-target activities [ABE]
GEO Series GSE129889. Homo sapiens. 48 samples. Type: Expression profiling by high throughput sequencing.
IDLV capture for gRNA off-target analysis
GEO Series GSE133861. Homo sapiens. 8 samples. Type: Expression profiling by high throughput sequencing.
Cas9 off-target binding to the promoter of bacterial genes leads to silencing and toxicity
GEO Series GSE217006. Escherichia coli. 18 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.
Widespread DNA off-targeting confounds studies of RNA chromatin occupancy
GEO Series GSE307444. Homo sapiens. 7 samples. Type: Other.
Promoter activity profiling reveals on- and off-target transcriptional responses to drug treatment
GEO Series GSE134817. Homo sapiens. 180 samples. Type: Expression profiling by high throughput sequencing.
Off-target effect of CWG-cPIP on gene expression of human fibroblasts
GEO Series GSE235810. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
Sensitive and unbiased genome-wide profiling of base-editor-induced off-target activity with CHANGE-seq-BE [Hybrid Capture Sequencing for Cas9]
GEO Series GSE307892. Homo sapiens. 18 samples. Type: Other.
Alteration of target cleavage patterns and off-target reduction of antisense oligonucleotides incorporating 2-N-carbamoyl- or (2-pyridyl)guanine [MALAT]
GEO Series GSE228740. Homo sapiens. 12 samples. Type: Expression profiling by high throughput sequencing.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.