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Fig. 7 in An Early Triassic gladius associated with soft tissue remains from Idaho, USA-a squid-like coleoid cephalopod at the onset of Mesozoic Era
Fig. 7. Coleoid cephalopod Idahoteuthis parisiana Doguzhaeva and Brayard gen. et sp. nov. (holotype, UBGD 30545); middle Olenekian, Early Triassic; Idaho, USA; cartilaginous mantle band-shape structure on the dorsal side of soft body. Overview (A) and detail of analicular cartilage (B). Abbreviation: dcm, dorsal cartilaginous mantle.
Fig. 9 in An Early Triassic gladius associated with soft tissue remains from Idaho, USA-a squid-like coleoid cephalopod at the onset of Mesozoic Era
Fig. 9. Coleoid cephalopod Idahoteuthis parisiana Doguzhaeva and Brayard gen. et sp. nov. (holotype, UBGD 30545); middle Olenekian, Early Triassic; Idaho, USA; globular ultrastructure of non-biomineralized structures. A. Sheet-like patch of flooded ink (top) and soft tissue debris (bottom); a site of the geochemical analysis is marked with a square. B. Undetermined long soft tissue piece showing a micro-granular ultrastructure on the dorsal side of the soft body. C. Micro-laminated ultrastructure of the gladius. D. Undetermined non-biomineralized micro-laminated fragment from the stomach. E. A linear fragment of soft tissue on dorsal side of the body. F. Micro-globular ultrastructure. Abbreviations: i, ink sheet-like patch; sbt, soft body tissues; std, soft tissue debris.
Fig. 6 in An Early Triassic gladius associated with soft tissue remains from Idaho, USA-a squid-like coleoid cephalopod at the onset of Mesozoic Era
Fig. 6. Coleoid cephalopod Idahoteuthis parisiana Doguzhaeva and Brayard gen. et sp. nov. (holotype, UBGD 30545); middle Olenekian, Early Triassic; Idaho, USA; views on the canalicular structure of fin-supported cartilages (A–D).
Fig. 1. A in An Early Triassic gladius associated with soft tissue remains from Idaho, USA-a squid-like coleoid cephalopod at the onset of Mesozoic Era
Fig. 1. A. Palaeogeographic map of the western USA basin during the Early Triassic. B. Present-day location of the studied exposure. C. Synthetic stratigraphical and lithological succession of the Bear Lake area (after Romano et al. 2013) with position of the studied specimen. Ammonoid zonation after Jenks et al. (2013) and Jattiot et al. (2016). Stratigraphy follows the main units defined by Kummel (1954). Radiometric ages after Galfetti et al. (2007) and Burgess et al. (2014). Abbreviations: LL, Lower Limestone; LS,Lower Shale; ML, Middle Limestone; MS, Middle Shale; UCS, Upper Calcareous Siltstone.
Fig. 4 in An Early Triassic gladius associated with soft tissue remains from Idaho, USA-a squid-like coleoid cephalopod at the onset of Mesozoic Era
Fig. 4. Coleoid cephalopod Idahoteuthis parisiana Doguzhaeva and Brayard gen. et sp. nov. (holotype, UBGD 30545); middle Olenekian, Early Triassic; Idaho, USA; arm-hooks in the stomach. A. A well exposed arm-hook with deformed shaft and a broken distal end of the basement, tip not exposed; another arm-hook less visible and fractured. B. Three deformed arm-hooks. C. A deformed arm-hook showing a depression along the compressed shaft. Abbreviations: h, arm-hook; i, ink sheet-like patch.
Fig. 5 in An Early Triassic gladius associated with soft tissue remains from Idaho, USA-a squid-like coleoid cephalopod at the onset of Mesozoic Era
Fig. 5. Coleoid cephalopod Idahoteuthis parisiana Doguzhaeva and Brayard gen. et sp. nov. (holotype, UBGD 30545); middle Olenekian, Early Triassic; Idaho, USA; fin-supported cartilages. The surfaces of fractured cartilages (A–C), outer surface (D). Abbreviation: f, fin.
Fig. 3 in An Early Triassic gladius associated with soft tissue remains from Idaho, USA-a squid-like coleoid cephalopod at the onset of Mesozoic Era
Fig. 3. Coleoid cephalopod Idahoteuthis parisiana Doguzhaeva and Brayard gen. et sp. nov. (holotype, UBGD 30545); middle Olenekian, Early Triassic; Idaho, USA; a folded tapered anterior part of the gladius with a rachis, and narrow median and acute left and right lateral fields. Abbreviations: lf, left lateral field; mf, median field; rf, right lateral field; sbr, soft body remains.
Data used in analyses of Danaher et al. 2024 "Childhood-onset lupus nephritis is characterized by complex interactions between kidney stroma and infiltrating immune cells"
<p>CosMx 1000-plex data and R code from childhood-onset lupus nephris samples, generated for the article Danaher et al. 2024 "Childhood-onset lupus nephritis is characterized by complex interactions between kidney stroma and infiltrating immune cells".</p>
Snow melt onset date estimates derived from CLARA-A2 SAL surface albedo dataset
<p>Snow melt onset date estimates for the Northern Hemisphere, 1982-2015. Derived from the CLARA-A2 SAL surface albedo dataset. Version for manuscript review.</p>
Size-associated energetic constraints on the seasonal onset of reproduction in a species with indeterminate growth
<p>The seasonal onset of reproduction is constrained in many systems by a need to first accumulate energetic reserves. Consequently, the observation that larger individuals reproduce earlier may be due to a negative relationship between size and mass-specific basal metabolic rate that is shared across diverse taxa. However, an untested prediction of this hypothesis is that individuals should be metabolically efficient enough to escape energetic constraints above a certain size threshold. Seasonally reproducing species, such as temperate fishes, that must recover winter energy losses before reproduction and exhibit indeterminate growth are ideal models to test this prediction. We harness decade-long behavioral data on parental male smallmouth bass, <em>Micropterus dolomieu</em>, to investigate contributions of energetic allometry to differences in reproductive timing. At the population level, peak seasonal reproductive timing (i.e., the median date on which eggs were found in nests each year) was negatively related to degree days–a measure of thermal energy experienced–before reproduction. At the individual level, degree days accumulated by males before reproduction was related to male size and condition in every year, but the impact of temperature on reproductive timing by the largest males was relaxed in most years. Additionally, we used our data to replicate the analyses of two previous studies of <em>M. dolomieu</em> populations and found virtually identical negative associations between male body size and degree days accumulated before reproduction. Our results suggest that in smallmouth bass the onset of seasonal reproduction is constrained by basal metabolic rate–as indicated by total length–and that large individuals can escape size-associated energetic constraints. We reveal a more complicated relationship between size and reproductive timing than earlier studies, which may be relevant for many species. Knowledge of this relationship is critical to understanding how a changing climate will influence population dynamics of economically, ecologically, and recreationally important species like <em>M. dolomieu</em>.</p>
Dimerization of melanocortin 4 receptor controls puberty onset and body size polymorphism
<p>Example dataset and scripts used in the analysis of PIE-based FRET-FLIM data of the Mc4r receptor. </p>
Data for: Faster growth and larger size at crèche onset are associated with higher offspring survival in Adélie Penguins
<p>We conducted the first assessment of Adélie Penguin chick survival that accounts for imperfect resighting. We found that when chicks are larger in size when they enter the crèche stage (the period when both parents forage at the same time and chicks are left relatively unprotected), they have a higher probability of survival to fledging. We investigated the relationships between growth, crèche-timing, and chick survival during one typical year and one year of reduced food availability. Chicks that hatched earlier in the season entered the crèche stage older, and chicks that both grew faster and crèched older entered the crèche at a larger size. These relationships were stronger in the year of reduced food availability. Thus, parents increased their chicks' chance of fledging if they provided sufficient food for faster growth rates and/or extended the length of the brood-guarding period. Early nest initiation (i.e., early hatching) provided parents with the opportunity to extend the guard period and increase chick survival. However, to extend the guard stage successfully, they must provide larger meals and maintain higher chick growth rates, even if just one parent at a time is foraging, which previous work has shown is not possible for all individuals. We show that the factors governing trade-offs in chick-rearing behavior of Adélie Penguin parents may vary in accord with environmental conditions, a result from which we can better understand species' adaptations to environmental changes.</p>
datset related to article "THE NOVEL I213S MUTATION IN PSEN1 GENE IS LOCATED IN A HOTSPOT CODON ASSOCIATED WITH FAMILIAL EARLY-ONSET ALZHEIMER'S DISEASE"
<p><strong>Electropherogram of the proband psen1 exon 7</strong></p> <p><strong>ngs analysis of causal and risk genes associated to dementia</strong></p>
Study of the Efficacy of Early Intervention With Secukinumab 300 mg s.c. Compared to Narrow-band UVB in Patients With New-onset Moderate to Severe Plaque Psoriasis
ClinicalTrials.gov study NCT03020199. IPD Sharing: YES. Countries: 13. Publications: 0.
A Placebo-controlled Study of Efficacy & Safety of 2 Trough-ranges of Everolimus as Adjunctive Therapy in Patients With Tuberous Sclerosis Complex (TSC) & Refractory Partial-onset Seizures
ClinicalTrials.gov study NCT01713946. IPD Sharing: YES. Countries: 25. Publications: 3.
Study to Compare the Efficacy and Safety of Enzyme Replacement Therapies Avalglucosidase Alfa and Alglucosidase Alfa Administered Every Other Week in Patients With Late-onset Pompe Disease Who Have No
ClinicalTrials.gov study NCT02782741. IPD Sharing: YES. Countries: 25. Publications: 4.
Recent-Onset Type 1 Diabetes Trial Evaluating Efficacy and Safety of Teplizumab
ClinicalTrials.gov study NCT03875729. IPD Sharing: YES. Countries: 9. Publications: 3.
A Study to Assess Safety and Efficacy of Avalglucosidase Alfa Administered Every Other Week in Pediatric Patients With Infantile-onset Pompe Disease Previously Treated With Alglucosidase Alfa
ClinicalTrials.gov study NCT03019406. IPD Sharing: YES. Countries: 5. Publications: 2.
SKIPPAIN - Speed of Onset of SecuKinumab-Induced Relief From Pain in Patients With AxIal SpoNdyloarthritis
ClinicalTrials.gov study NCT03136861. IPD Sharing: YES. Countries: 17. Publications: 1.
A Multinational, Randomized, Double-blind, Placebo-controlled Study to Assess the Efficacy, Pharmacodynamics, Pharmacokinetics, and Safety of Venglustat in Late-onset GM2
ClinicalTrials.gov study NCT04221451. IPD Sharing: YES. Countries: 13. Publications: 1.
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.