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429 results for “physiological data”
Data for: Upslope migration is slower in species with high physiological demands
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Data from: Hypoxia disrupts sex-specific physiology and gene expression leading to decreased fitness in the estuarine sea anemone Nematostella vectensis
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Data from: In vitro to in vivo extrapolation from three-dimensional hiPSC-derived cardiac microtissues and physiologically based pharmacokinetic modeling to inform next-generation arrythmia risk assessment
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Supplementary datasets, data analysis code, and R tutorials for: Phylogenetic analysis of adaptation in comparative physiology and biomechanics: overview and a case study of thermal physiology in treefrogs
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Data from: A reaction norm for flowering time plasticity reveals physiological footprints of maize adaptation
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Data from: Early-life exposure to artificial light at night elevates physiological stress in free-living songbirds
<p>Artificial light at night (ALAN) can disrupt adaptive patterns of physiology and behavior that promote high fitness, resulting in physiological stress and elevation of steroid glucocorticoids (corticosterone, CORT in birds). Elevated CORT may have particularly profound effects early in life, with the potential for enduring effects that persist into adulthood. Research on the consequences of early-life exposure to ALAN remains limited, especially outside of the laboratory, and whether light exposure affects CORT concentrations in wild nestling birds particularly remains to be elucidated. We used an experimental setup to test the hypothesis that ALAN elevates CORT concentrations in developing free-living birds, by exposing nestling great tits (Parus major) to ALAN inside nest boxes. We measured CORT in feathers grown over the timeframe of the experiment (7 nights), such that CORT concentrations represent an integrative metric of hormone release over the period of nocturnal light exposure, and of development. We also assessed the relationships between feather CORT concentrations, body condition, nestling size rank and fledging success. In addition, we evaluated the relationship between feather CORT concentrations and telomere length. Nestlings exposed to ALAN had higher feather CORT concentrations than control nestlings, and nestlings in poorer body condition and smaller brood members also had higher CORT. On the other hand, telomere length, fledging success, and recruitment rate were not significantly associated with light exposure or feather CORT concentrations. Results indicate that exposure to ALAN elevates CORT concentrations in nestlings, which may reflect physiological stress. In addition, the organizational effects of CORT are known to be substantial. Thus, despite the lack of an effect on telomere length and survivorship, elevated CORT concentrations in nestlings exposed to ALAN may have subsequent impacts on later-life fitness and stress sensitivity.</p>
Data from: Vascular epiphytes show low physiological resistance and high recovery capacity to episodic, short-term drought in Monteverde, Costa Rica
<ol> <li>Tropical montane cloud forests support abundant epiphytic vascular plant communities that serve important ecosystem functions, but their reliance on atmospheric inputs of water may make them susceptible to the drying effects of rising cloud bases and more frequent droughts.</li> <li>We conducted a common garden experiment to explore the combined effects of decreasing cloud influence—lower humidity, warmer temperature, brighter light—and meteorological drought (i.e., absence of rain) on the physiology and morphology of vascular epiphytes native to primary forests of Monteverde, Costa Rica. The epiphytes, which exhibited C<sub>3</sub> photosynthesis, were sourced from a lower montane cloud forest (CF) or a rainforest below the current cloud base (RF) and transplanted into nearby shadehouses (CF or RF shadehouse, respectively). Vapor pressure deficit (VPD) and light availability, measured as photosynthetically active radiation, were 2.5 and 3.1 times higher in the RF than the CF shadehouse. Half of the plants were subjected to a severe four-week drought followed by a recovery period, and the other half were watered controls.</li> <li>Plants subjected to low VPD/light conditions of the CF shadehouse were physiologically and morphologically resistant to the drought treatment. However, compared to control plants, both sources of plants subjected to high VPD/light conditions of the RF shadehouse experienced declines in maximum net photosynthesis (A<sub>max</sub>), stomatal conductance (g<sub>s</sub>), and the proportion of healthy leaves (those not exhibiting chlorosis, desiccation, or necrosis). At peak drought, leaves from the RF were 19% thinner than controls. Within 7-14 days after rewatering, A<sub>max</sub>, g<sub>s</sub>, and leaf health recovered to nearly the levels of controls. Growth rate, mortality, and phenology were unaffected by the treatments.</li> <li>The divergent responses to drought in the CF versus RF shadehouses, combined with the recovery in the RF shadehouse, indicate that these epiphytes possess adaptive properties that confer low resistance, but high recovery capacity, to episodes of short-term drought over a range of cloud influence. In addition, the reduction in A<sub>max</sub> suggests stomatal regulation that favors water conservation over carbon acquisition, a strategy that may inform epiphyte responses to rising clouds and increasing drought frequency expected in the long term.</li> </ol>
Data From: Contrasting physiological traits of shade tolerance in Pinus and Podocarpaceae native to a tropical Vietnamese forest: Insight from an aberrant flat-leaved pine
<p>The absence of pines from tropical forests is a puzzling biogeographical oddity potentially explained by traits of shade intolerance. <i>Pinus krempfii</i>, a flat-leaved pine endemic to the Central Highlands of Vietnam, provides a notable exception as it seems to successfully compete with shade-tolerant tropical species. Here, we test the hypothesis that successful conifer performance at the juvenile stage depends on physiological traits of shade tolerance by comparing the physiological characteristics of <i>P. krempfii </i>to coexisting species from the genus <i>Pinus</i> and from the Podocarpaceae, a relatively abundant and shade tolerant conifer family found in pantropical forests. We examined leaf photosynthetic, respiratory and biochemical traits. Additionally, we compiled attainable maximum photosynthesis, maximum RuBP carboxylation (<i>Vc</i><sub>max</sub>) and maximum electron transport (<i>J</i><sub>max</sub>) values for <i>Pinus</i> and Podocarpaceae species from the literature. In our literature compilation, <i>P. krempfii </i>was intermediate between <i>Pinus</i> and Podocarpaceae in its maximum photosynthesis and its <i>Vc</i><sub>max</sub>. <i>Pinus</i> exhibited a higher <i>Vc</i><sub>max</sub> than Podocarpaceae, resulting in a less steep slope in the linear relationship between <i>J</i><sub>max</sub> and <i>Vc</i><sub>max</sub>. These results suggest that <i>Pinus </i>may be more shade intolerant than Podocarpaceae with <i>P. krempfii </i>falling between the two groups. However, in contrast, Vietnamese conifers' leaf mass per areas and biochemical traits did not highlight the same intermediate nature of <i>P. krempfii</i>. Furthermore, regardless of leaf shape or family assignation, all species demonstrated a common carbon gain efficiency. Overall, our findings highlight the importance of shade tolerance for conifer survival in tropical forests. However, they also demonstrate a diversity of shade tolerance strategies, all of which lead to the persistence of Vietnamese juvenile conifers in low-light tropical understories.</p>
Data from: Metabolic rate shapes phenotypic covariance among physiological, behavioural, and life history traits in honeybees
<p>Metabolic rate is often cited as the fundamental rate that determines the rate of all biological processes by shaping energetic availability for the various behavioral and life history traits that contribute to performance. It has therefore been suggested that metabolic rate drives the widely observed covariance among these different levels of phenotypic traits. However, much of the work on this topic has relied on pairwise correlational analysis, thereby leaving an important gap in our understanding regarding the functional links that shape this phenotypic covariance, often referred to as pace-of-life. Using honeybees as an experimental model, we measured a large number of behavioural, life history and physiological traits in individual bees and used a structural equation model to characterize the phenotypic covariance structure among these traits. Following this with a path analysis, we demonstrate that variation in metabolic rate plays a fundamental proximate role in driving this phenotypic covariance structure in honeybees. We discuss the importance of these findings in the context of how interindividual variation in terms of slow-fast phenotypes may drive the phenotype of a group and the functional role metabolic rate might play in shaping division of labour and social evolution.</p>
Central processing of leg proprioception in Drosophila: Physiology and behavior data
<p>Proprioception, the sense of self-movement and position, is mediated by mechanosensory neurons that detect diverse features of body kinematics. Although proprioceptive feedback is crucial for accurate motor control, little is known about how downstream circuits transform limb sensory information to guide motor output. Here, we investigate neural circuits in <i>Drosophila </i>that process proprioceptive information from the fly leg. We identify three cell-types from distinct developmental lineages that are positioned to receive input from proprioceptor subtypes encoding tibia position, movement, and vibration. 13Bα neurons encode femur-tibia joint angle and mediate postural changes in tibia position. 9Aα neurons also drive changes in leg posture, but encode a combination of directional movement, high-frequency vibration, and joint angle. Activating 10Bα neurons, which encode tibia vibration at specific joint angles, elicits pausing in walking flies. Altogether, our results reveal that central circuits integrate information across proprioceptor subtypes to construct complex sensorimotor representations that mediate diverse behaviors, including reflexive control of limb posture and detection of leg vibration.</p>
Data from: Effects of dry-season irrigation on leaf physiology and biomass allocation in tropical lianas and trees
Lianas are more abundant in seasonal forests than in wetter forests and are thought to perform better than trees when light is abundant and water is limited. We tested the hypothesis that lianas perform better than trees during seasonal drought using a common garden experiment with 12 taxonomically diverse species (6 liana and 6 tree species) in 12 replicated plots. We irrigated six of the plots during the dry season for four years, while the remaining 6 control plots received only ambient rainfall. In year 5, we measured stem diameters for all individuals and harvested above- and belowground biomass for a subset of individuals to quantify absolute growth and biomass allocation to roots, stems, and leaves, as well as total root length and maximum rooting depth. We also measured photosynthesis, intrinsic water use efficiency (iWUE), pre-dawn and midday water potential, and a set of functional and hydraulic traits. During the peak of the dry season, lianas in control plots had 54% higher predawn leaf water potentials (ΨPD), and 45% higher photosynthetic rates than trees in control plots. By contrast, during the peak of the wet season, these physiological differences between lianas and trees become less pronounced and, in some cases, even disappeared. Trees had higher SLA than lianas; however, no other functional trait differed between growth forms. Trees responded to the irrigation treatment with 15% larger diameters and 119% greater biomass than trees in control plots. Liana growth, however, did not respond to irrigation; liana diameter and biomass were similar in control and irrigation plots, suggesting that lianas were far less limited by soil moisture than were trees. Contrary to previous hypotheses, lianas did not have deeper roots than trees; however, lianas had longer roots per stem diameter than did trees. Our results support the hypothesis that lianas perform better and experience less physiological stress than trees during seasonal drought, suggesting clear differences between growth forms in response to altered rainfall regimes. Ultimately, better dry-season performance may explain why liana abundance peaks in seasonal forests compared to trees, which peak in abundance in less seasonal, wetter forests.
Data from: Physiological predictors of reproductive performance in the European Starling (Sturnus vulgaris)
Background: It is widely assumed that variation in fitness components has a physiological basis that might underlie selection on trade-offs, but the mechanisms driving decreased survival and future fecundity remain elusive. Here, we assessed whether physiological variables are related to workload ability or immediate fitness consequences and if they mediate future survival or reproductive success. We used data on 13 physiological variables measured in 93 female European starlings (Sturnus vulgaris) at two breeding stages (incubation, chick-rearing), for first-and second-broods over two years (152 observations). Results: There was little co-variation among the physiological variables, either in incubating or chick-rearing birds, but some systematic physiological differences between the two stages. Chick-rearing birds had lower hematocrit and plasma creatine kinase but higher hemoglobin, triglyceride and uric acid levels. Only plasma corticosterone was repeatable between incubation and chick-rearing. We assessed relationships between incubation or chick-rearing physiology and measures of workload, current productivity, future fecundity or survival in a univariate manner, and found very few significant relationships. Thus, we next explored the utility of multivariate analysis (principal components analysis, Mahalanobis distance) to account for potentially complex physiological integration, but still found no clear associations. Conclusions: This implies either that a) birds maintained physiological variables within a homeostatic range that did not affect their performance, b) there are relatively few links between physiology and performance, or, more likely, c) that the complexity of these relationships exceeds our ability to measure it. Variability in ecological context may complicate the relationship between physiology and behavior. We thus urge caution regarding the over-interpretation of isolated significant findings, based on single traits in single years, in the literature.
Data from: Morphological and physiological consequences of a dietary restriction during early life in bats
<p>Early life adverse conditions can have major consequences on an individual's life history traits. Oxidative stress has been hypothesized to be one main mechanism underlying the negative consequences of early life adverse conditions. To test this hypothesis, we restricted the food availability of Seba's short-tailed bat (Carollia perspicillata) mothers of unweaned pups for 10 days, followed by ad libitum provisioning. We also had a control, unrestricted group. We explored the morphological consequences of dietary restriction during early life by measuring growth rate. We also measured four markers of blood oxidative balance during growth. We assessed the level of cortisol, and its inactive form cortisone, in the hair of the pups at the end of growth. Finally, we monitored survival during the first year. Food restriction triggered a slowdown in growth followed by catch-up growth when ad libitum feeding was restored which did not lead to full compensation in size or mass compared to control individuals. We found that higher growth rate was associated with elevated oxidative damage, suggesting an oxidative cost to growth.However, we found no clear evidence for physiological costs specific to the catch-up growth. Survival after a year was not impacted by the treatment, the oxidative balance or the level of glucocorticoids at the end of growth. In conclusion, our results show that individuals were able to efficiently mitigate the short-term consequences of adverse early life conditions. However, consequences might arise on the long-term, and could impact reproductive success or lifespan.</p>
Data from: Assessing the influence of biotic, abiotic, and social factors on the physiological stress of a large Neotropical primate in Atlantic Forest fragments
Wildlife physiological responses to environmental and human-related stressors provide useful clues on animal welfare. Non-invasive biomarkers, such as fecal glucocorticoid metabolites (fGCM), allow researchers to assess whether variations in habitat quality, behavior, and climate influence the animals' physiological stress. We examined the role of fragment size, ambient temperature, ripe fruit availability and consumption, percentage of records moving, sex, female reproductive state, and group composition as predictors of the level of fGCM in adult brown howler monkeys (Alouatta guariba clamitans) inhabiting three small (<10 ha) and three large (>90 ha) Atlantic Forest fragments in southern Brazil. We collected bimonthly behavioral data and fecal samples from adult individuals over three years, and used a multimodel inference framework to identify the main predictors of fGCM. We found that the mean (±SD) fGCM in the study groups ranged from 57 ± 49 ng/g to 93 ± 58 ng/g, which were within the known range for howler monkeys. We found 10 best models including five of the 17 tested variables. Sex and reproductive state were the only variables included in all these models. We found that fGCM was higher in nursing females (mean ± SD = 104 ± 73 ng/g) than in non-nursing females (64 ± 55 ng/g) and males (53 ± 40 ng/g, P < 0.05) and that it decreased with increasing ripe fruit consumption and minimum temperature. However, fragment size did not predict fGCM concentration (groups in small fragments = 71 ± 58 ng/g vs. groups in large fragments = 63 ± 54 ng/g, P > 0.05). We conclude that factors related to the energetic balance of individuals play major roles in modulating the physiological stress of brown howler monkeys. Future studies should investigate the consequences of higher levels of stress hormones on howler monkey health and demography.
Data from: Age‐dependent leaf physiology and consequences for crown‐scale carbon uptake during the dry season in an Amazon evergreen forest
* Satellite and tower-based metrics of forest-scale photosynthesis generally increase with dry season progression across central Amazônia, but the underlying mechanisms lack consensus. * We conducted demographic surveys of leaf age composition, and measured age-dependence of leaf physiology in broadleaf canopy trees of abundant species at a central eastern Amazon site. Using a novel leaf-to-branch scaling approach, we used this data to independently test the much-debated hypothesis—arising from satellite and tower-based observations—that leaf phenology could explain the forest-scale pattern of dry season photosynthesis. * Stomatal conductance and biochemical parameters of photosynthesis were higher for recently mature leaves than for old leaves. Most branches had multiple leaf age categories simultaneously present, and the number of recently mature leaves increased as the dry season progressed because old leaves were exchanged for new leaves. * These findings provide the first direct field evidence that branch-scale photosynthetic capacity increases during the dry season, with a magnitude consistent with increases in ecosystem-scale photosynthetic capacity derived from flux towers. Interaction between leaf age-dependent physiology and shifting leaf age-demographic composition are sufficient to explain the dry season photosynthetic capacity pattern at this site, and should be considered in vegetation models of tropical evergreen forests.
BurnCare Physiology Data: Burn with Resuscitation
<p>A standard male patient with burns from 20-40% TBSA were simulated through 24 hours with intervention and state files were generated every fifteen minutes. In these resuscitation protocols, we opt to use only lactated ringers, and no colloid compounds. The data includes a log and csv results file for each simulation. The "golden path" of treatment starts the resuscitation pathway with fluids being given at a rate of 10xTBSA (then titrated up or down each hour based on urine output). The naming structure for each state consists of tbsa, simulation time, current ringers lactate infusion rate, and colloid infusion rate (for future treatment protocols).</p>
Assessment of endothelial cell function and physiological microcirculatory reserve by video microscopy using a topical acetylcholine and nitroglycerin challenge - Individual subject data
<p>This dataset contains individual subject data for microcirculatory parameters assessed in the present study. Macrocirculatory parameters are not included at this time due to the present study being part of a larger, partially unpublished project.</p>
Hellenistic-Roman bioarchaeological physiological stress data - MetaMobility project
<p>This database covers the bioarchaeological data we could extract on Hellenistic-Roman period physiological stress markers in the Central and Eastern Mediterranean and Middle East. Specifically, it covers cases of cribra orbitalia, porotic hyperostosis, enamel hypoplasia and periostitis. The database was created as part of the MetaMobility project (EXCELLENCE/0421/0376), which is implemented under the programme of social cohesion “THALIA 2021-2027” cofunded by the European Union, through the Research and Innovation Foundation.</p>
Data from: Physiological effects of interacting native and invasive bivalves under thermal stress
<p>Across many ecosystems in North America and Europe, native freshwater bivalves (Order Unionida) are threatened by fouling and competition for food by the invasive zebra mussel <em>Dreissena polymorpha</em>. In light of climate change, knowledge on the influence of water temperature on these competitive effects is important, yet poorly understood. This study examines the physiological impact of the interaction between <em>D. polymorpha</em> and the native European unionid <em>Anodonta cygnea</em> over a 28-day period in response to water temperatures of 12, 19, and 25 °C by comparing their glycogen, glucose, lipid, and protein concentrations. The laboratory experiment comprised three treatments: (1) fouling of <em>A. cygnea</em> by <em>D. polymorpha</em>, (2) both species present but not fouling; and (3) a control in which <em>A. cygnea</em> and <em>D.</em> <em>polymorpha</em> were placed separately. Increased water temperatures caused physiological stress in <em>D. polymorpha</em> as evident from reduced glycogen, glucose, lipid, and protein concentrations. <em>Dreissena polymorpha</em> benefited from fouling of unionids, as individuals that fouled <em>A. cygnea</em> tended to have increased glycogen, glucose, lipid and protein concentrations. Competitive effects of <em>D. polymorpha</em> over the unionid bivalve species, however, were not intensified by elevated temperatures. Glochidia release, lower infestation intensity, and physiological stress of <em>Dreissena </em>at higher temperatures were likely confounding factors. The results of this study suggest that understanding the physiological consequences of species interactions at changing temperatures can be an important tool to assess future climate change impacts on freshwater bivalves and aquatic community structures.</p>
Physiological and environmental data from: Are you ready for the heat? Plasticity vs adaptation of heat tolerance in three-spined stickleback
<p>Heat waves constitute a challenge for aquatic ectotherms. However, the thermal tolerance of animals and their individual phenotypic plasticity to respond to heat waves may be influenced by thermal history. We tested these hypotheses by comparing the upper thermal tolerance and the individual capacities of three-spined sticklebacks from populations with different thermal histories to respond to heat waves. Two populations originated from thermally polluted nuclear power plant (NPP) habitats, while four locations represented geographically adjacent control areas. To disentangle the genetic adaptation from the phenotypic plastic response, we measured the individual upper thermal tolerance and the responses at molecular level in common garden conditions before and after a laboratory-mimicked heat wave. We found that the sticklebacks exhibit considerable phenotypic plasticity in thermal tolerance since the heat wave increased fish upper thermal tolerance significantly. The individual plasticity to respond to the heat wave was also negatively correlated to initial thermal tolerance. On the other hand, neither the thermal tolerance nor the plastic responses differed between NPP and control sites despite detection of significant but low genome-wide divergence in 10 out of 15 pairwise comparisons. Our results suggest that five decades of nuclear power plant activity with warmer water has not resulted in a detectable evolutionary change in either the upper thermal tolerance or its plasticity in three-spined sticklebacks potentially rendering them sensitive to frequent heat waves.</p>
ScienceDex guides
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.