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96
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ShareScore release 0.9.0
Dataset results
96 results for “positive feedback”
A stimulus-contingent positive feedback loop enables IFN-β dose-dependent activation of pro-inflammatory genes
GEO Series GSE219283. Mus musculus. 62 samples. Type: Expression profiling by high throughput sequencing.
EZH2 enables germinal center formation through epigenetic silencing of CDKN1A and an Rb-E2F1 positive feedback loop
GEO Series GSE95491. Mus musculus. 49 samples. Type: Expression profiling by high throughput sequencing.
IMPDH1/YB-1 Positive Feedback Loop Assembles Cytoophidia and Represents a Therapeutic Target in Metastatic Tumors
GEO Series GSE146231. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
Analyses of RNAi-heterochromatin positive feedback loop in Tetrahymena
GEO Series GSE87015. Tetrahymena thermophila. 36 samples. Type: Genome binding/occupancy profiling by high throughput sequencing; Non-coding RNA profiling by high throughput sequencing.
Stabilization of mitochondrial double stranded RNAs by SLIRP promotes positive feedback amplification of antiviral signaling.
GEO Series GSE248259. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
The HIF-1α antisense long non-coding RNA drives a positive feedback loop of HIF-1α mediated transactivation and glycolysis
GEO Series GSE159490. Homo sapiens. 12 samples. Type: Non-coding RNA profiling by array; Expression profiling by array.
Analyses of heterochromatin distributions in the mutatnts defective in an RNAi-heterochromatin positive feedback loop in Tetrahymena [ChIP]
GEO Series GSE87013. Tetrahymena thermophila. 22 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Analyses of scnRNAs in the mutatnts defective in an RNAi-heterochromatin positive feedback loop in Tetrahymena [scnRNA]
GEO Series GSE87011. Tetrahymena thermophila. 14 samples. Type: Non-coding RNA profiling by high throughput sequencing.
A positive feedback circuit between mTORC1 signaling and cathelicidin promotes skin inflammation in rosacea [mouse]
GEO Series GSE147950. Mus musculus. 12 samples. Type: Expression profiling by high throughput sequencing.
The ELAVL3/MYCN positive feedback loop provides a therapeutic target for neuroendocrine prostate cancer
GEO Series GSE224911. Homo sapiens. 20 samples. Type: Expression profiling by high throughput sequencing; Other.
Astrocyte-to-astrocyte contact and a positive feedback loop of growth factor signaling regulate astrocyte maturation
GEO Series GSE125610. Mus musculus. 25 samples. Type: Expression profiling by high throughput sequencing.
A positive feedback loop links opposing functions of P-TEFb/Cdk9 and histone H2B mono-ubiquitylation to regulate transcript elongation in fission yeast
GEO Series GSE31070. Schizosaccharomyces pombe. 6 samples. Type: Genome binding/occupancy profiling by genome tiling array.
The vascular endothelial thromboxane A2/prostaglandin H2 receptor controls its own activation and impairs angiogenesis via an autocrine cyclooxygenase-2-dependent positive feedback loop.
GEO Series GSE146888. Homo sapiens. 9 samples. Type: Expression profiling by high throughput sequencing.
The MAPK14/MAPK7/BCL6B pathway creates a positive feedback loop to drive spermatogonial stem cell (SSC) self-renewal via ROS amplification.
GEO Series GSE118191. Mus musculus. 16 samples. Type: Expression profiling by high throughput sequencing.
EIN3 positive feedback regulation on EIN2C-mediated histone acetylation and gene expression
GEO Series GSE138154. Arabidopsis thaliana. 16 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing; Third-party reanalysis.
Th1 polarization in Bordetella pertussis vaccine responses is maintained through a positive feedback loop
GEO Series GSE274944. Homo sapiens. 327 samples. Type: Expression profiling by high throughput sequencing.
A PINK1 input threshold arises from positive feedback in the PINK1/Parkin mitophagy decision circuit
<p><strong>Plasmid maps, single cell data, and analysis code for the journal article titled "A PINK1 input threshold arises from positive feedback in the PINK1/Parkin mitophagy decision circuit"</strong></p><p> </p><p>Mechanisms that prevent accidental activation of the PINK1/Parkin mitophagy circuit on healthy mitochondria are poorly understood. On the surface of damaged mitochondria, PINK1 accumulates and acts as the input signal to a positive feedback loop of Parkin recruitment, which in turn promotes mitochondrial degradation via mitophagy. However, PINK1 is also present on healthy mitochondria, where it could errantly recruit Parkin and thereby activate this positive feedback loop. Here, we explore emergent properties of the PINK1/Parkin circuit by quantifying the relationship between mitochondrial PINK1 concentrations and Parkin recruitment dynamics. We find that Parkin is recruited to mitochondria only if PINK1 levels exceed a threshold and then only after a delay that is inversely proportional to PINK1 levels. Furthermore, these two regulatory properties arise from the input-coupled positive feedback topology of the PINK1/Parkin circuit. These results outline an intrinsic mechanism by which the PINK1/Parkin circuit can avoid errant activation on healthy mitochondria.</p>
Visual Feedback Goggle for Positional Vertigo Treatment
ClinicalTrials.gov study NCT00729885. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Positive Feedback vs. No-Feedback Games for Behavioral Change
ClinicalTrials.gov study NCT06025838. IPD Sharing: YES. Countries: 1. Publications: 0.
Effectiveness of a Neuromuscular Exercise Program and Visual Feedback in the Management of Body Position for Stroke Survivors
ClinicalTrials.gov study NCT05187559. IPD Sharing: NO. Countries: 1. Publications: 0.
ScienceDex guides
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.