Find research datasets worth reusing
Search datasets from major research repositories and use ShareScore to quickly assess how well each record supports discovery, access, and reuse.
1,479
datasets available to search
ShareScore release 0.9.0
Dataset results
1,479 results for “priming”
Dataset to Schiedung et al (2023): Soil carbon losses due to priming moderated by adaptation and legacy effects
<p>Data set to: Schiedung et al. (2023) Soil carbon losses due to priming moderated by adaptation and legacy effects, Nature Geoscience</p> <p>All file informations are presented in 0_Read_me_description.csv</p> <p>All .csv files are separated by ",". All .xlsx files contain the isotopic excess calculations condcuted in Microsoft Excel (Version 2301 Build 16.0.16026.20002).</p> <p>This repository contains all data of the soils and sites, incubation and fractionation presented in the above mentioned publication.</p> <p>For further questions and requests contact Marcus Schiedung (marcusschiedung@gmail.com)</p>
An Anesthesia-Centered Bundle to Reduce Postoperative Pulmonary Complications: The PRIME-AIR Study
ClinicalTrials.gov study NCT04108130. IPD Sharing: YES. Countries: 1. Publications: 11.
Study of Dupilumab for the Treatment of Patients With Prurigo Nodularis, Inadequately Controlled on Topical Prescription Therapies or When Those Therapies Are Not Advisable (LIBERTY-PN PRIME)
ClinicalTrials.gov study NCT04183335. IPD Sharing: YES. Countries: 8. Publications: 3.
Expression of terminal deoxynucleotidyl transferase (TdT) identifies lymphoid-primed progenitors in human bone marrow
Open the record for dataset details and reuse information.
IFN-γ primes bone marrow neutrophils to acquire regulatory functions in severe viral respiratory infections
Open the record for dataset details and reuse information.
Data and code for: Acute heat priming promotes short-term climate resilience of early life stages in a model sea anemone
Open the record for dataset details and reuse information.
Safer and efficient base editing and prime editing via ribonucleoproteins delivered through optimized lipid-nanoparticle formulations
Open the record for dataset details and reuse information.
Grazing-N addition interactions drive soil carbon priming and balance via bacterial assimilation in a meadow steppe
Open the record for dataset details and reuse information.
Data from: Deletion of an sRNA primes development in a multicellular bacterium
Open the record for dataset details and reuse information.
Priming gestures with sounds - dataset
<p>These are the data of the corresponding manuscript: "Priming gestures with sounds" by Guillaume Lemaitre, Laurie M. Heller, Nicolas Zuñiga-Peñaranda and Nicole Navolio.</p> <p>There are five directories corresponding to the five experiments reported in the manuscript. These are Matlab .mat files. Each file corresponds to one participant. There are four variables:</p> <p>- Accuracy: 0 = incorrect answer; 1= correct answer</p> <p>- Time: response time in ms. </p> <p>- Congruency: type of trial. 1 = incongruent, 2=congruent, 3=nosound</p> <p>- Order: trial order.</p> <p>Each variable is Nx2 matrix. N is the number of trials. First line is left gesture, second line is right gesture. </p>
African Continent of Flags of Nations Animus Prime Research Collective
<p>In a remarkable show of unity and diversity, the nations of Africa came together to proudly display their national flags. This captivating sight was witnessed at an event that celebrated the rich cultural heritage and shared aspirations of the continent. The vibrant display of flags served as a visual reminder of the strong bond that unites the African nations. Representatives from each country unfurled their flags, each boasting a unique design and symbolism that reflects their individual history, traditions, and values. From the bold colors of Ghana's flag representing the country's vibrant spirit, to the symbol of peace and harmony depicted on the flag of Rwanda, the diversity of African culture was proudly showcased. The event was not only a celebration of diversity but also a demonstration of solidarity. As the flags fluttered in unison, it served as a powerful reminder of the collective strength and determination of the African nations to overcome challenges and work towards a brighter future. The flags also symbolized the shared purpose of the African nations to foster peace, stability, and development on the continent.</p><p> They stood as a testament to the commitment of African leaders and citizens to create a better tomorrow, one that is characterized by progress, prosperity, and mutual respect. During the event, attendees marveled at the array of flags on display, recognizing the rich tapestry of cultures and identities that make up the African continent. Visitors had the opportunity to learn about the unique stories and symbolism behind each flag, gaining a deeper appreciation for the values and aspirations of the respective countries. In addition to celebrating unity and diversity, the event aimed to promote cultural exchange and strengthen diplomatic ties among the African nations. Representatives engaged in fruitful discussions, forging new partnerships, and exploring avenues for collaboration in various fields, including trade, tourism, and education. As the event drew to a close, the resonance of this display of flags lingered in the hearts and minds of all who attended. The unity and diversity showcased through this visual spectacle served as a powerful reminder of what can be achieved when nations come together to celebrate their unique identities and work towards a common goal. As the flags were gently folded and put away, the spirit of unity continued to resonate, leaving a lasting impression on all who witnessed this magnificent display. The message was clear: when the nations of Africa stand together, they stand strong, united, and poised to overcome any challenge that comes their way. In the spirit of celebrating African culture and progress, let us honor this display of unity by embracing the values of diversity, solidarity, and collaboration. Together, we can build a brighter future for Africa and the world at large.</p>
mRNA prime–boost evolves precursors toward VRC01-like broadly neutralizing antibodies in preclinical humanized mouse models
<p>Germline-targeting (GT) protein immunogens to induce VRC01-class broadly neutralizing antibodies (bnAbs) to the CD4 binding site (CD4bs) of the HIV Envelope have shown promise in clinical trials. Here, we preclinically validated the mRNA-LNP delivery of one such immunogen, eOD-GT8, as a soluble self-assembling 60mer nanoparticle in humanized mouse models. In a model with three humanized B cell lineages bearing distinct VRC01-precursor B cell receptors (BCRs) with similar affinities for eOD-GT8, all lineages could be simultaneously primed and undergo diversification and affinity maturation with no sign of exclusionary competition. Boosts drove precursor B cell participation in germinal centers, the accumulation of somatic hypermutations, including in key VRC01-class positions, and affinity maturation to boost and native-like antigens in two of the three precursor lineages. We have preclinically validated a prime-boost regimen of soluble self-assembling nanoparticles delivered by mRNA-LNP, demonstrating that multiple lineages can be primed, boosted, and diversify along the bnAb pathway.</p>
Peripheral priming induces plastic transcriptomic and proteomic responses in circulating neutrophils required for pathogen containment
<p><strong>When using any of this data, please cite the corresponding manuscript</strong></p> <div> <div> <p><a title="Rainer Kaiser et al., Peripheral priming induces plastic transcriptomic and proteomic responses in circulating neutrophils required for pathogen containment.Sci. Adv.10,eadl1710(2024).DOI:10.1126/sciadv.adl1710" href="https://doi.org/10.1126/sciadv.adl1710">Rainer Kaiser et al., Peripheral priming induces plastic transcriptomic and proteomic responses in circulating neutrophils required for pathogen containment. Sci. Adv. 10, eadl1710 (2024). DOI:10.1126/sciadv.adl1710</a></p> </div> </div> <p><strong>Original Data</strong></p> <p>The following files contain all count data for the original data of this manuscript:</p> <p>sepsis1_raw_feature_bc_matrix.h5 -> raw feature barcode matrix for sepsis1 sequencing<br>sepsis1_velocyto.loom -> velocyto matrices for sepsis1<br>sepsis2_raw_feature_bc_matrix.h5 -> raw feature barcode matrix for sepsis2 sequencing<br>sepsis2_velocyto.loom -> velocyto matrices for sepsis2</p> <p>sepsis_seurat.rds -> processed Seurat object containing original data cells. (Upd.: the meta.data-column "cellnames" contains the cell type annotation given in Figure 1B)</p> <p><strong>Original Data Scripts</strong></p> <p>process.R -> main analysis script<br>functions.R -> helper functions for main analysis script<br>enrichmentAnalysis.R -> script running the enrichment analysis<br>process_wgcna.R -> script performing the wgcna analysis<br>velocities_step1.R -> script performing velocity analysis (from seurat to data matrices)<br>velocities_step2.py -> actual velocity analysis<br><br><strong>GSE137539 Re-Analysis</strong></p> <p>gse137539_processed.Rds -> processed seurat object<br>gse137539_process.R -> analysis script</p> <p><strong>Bulk Analysis</strong></p> <p>MOUSE_SEPTIC_SEPTICACT.inex.DirectDESeq2.xlsx-> Raw UMI counts (intronic+exonic from zUMIs) and DE genes<br>MOUSE_SEPTIC_SEPTICACT.inex.DirectDESeq2.tsv.GeneOntology.BP.up.gsea.tsv -> Gene Set Enrichment Analysis on up-regulated genes using Gene Ontology Biological Process</p>
Residual limb models scanned using the EINScan Pro 2X Plus scanner with added HD Prime Pack
<p>This dataset contains limb models scanned using the EINScan Pro 2X Plus scanner. At each of 3 sites, operator 1 (OP1) scanned the four limb models twice (OP1-A and OP1-B) with the structured-light scanner, and operator 2 (OP2) scanned the four limb models once with the same scanner, for a total of 12 scans per site. At the European site, an additional reference scan of each positive model (4 scans) was conducted by an independent professional Operator (OP0) using the metrological scanner (EINScan Laser FreeScan 5X). </p>
Stocks data of Stocks in the German Prime Standard 2018
<p>Data was used in publication:</p> <p>Thrun, M. C.: Exploiting Distance-Based Structures in Data Using an Explainable AI for Stock Picking, Information, MDPI, 2022.</p> <p>Using this data please cite the publication.</p>
Self-adjuvanting Nanovaccines Boost Lung-resident CD4+ T Cell Immune Responses in BCG-primed mice
<p>The "readcount_genename.xls" file and "fpkm_genename.xls" file contain gene expression data for genes (gene list is detailed in "gene.xls") in the panel. All data were obtained from bone marrow derived dendritic cells from WT C57BL/6 mice treated with KFE8 nanofibers or mock. All RNA sequencing and subsequent processing was performed by Novogene Corporation.</p> <p>The remaining .xls files contain the differential expression analysis for KFE8 nanofiber treatment at four hours compared with mock (NF4vsC4) or KFE8 nanofiber treatment at sixteen hours compared with mock (NF16vsC16).</p> <p>The "pathway analysis Rcode.R" file contains the code used to generate Reactome pathway analysis for both time points. </p> <p>The "NF16 volc Rcode.R" file contains the code used to generate a volcano plot for the 16 hour time point. </p>
Anoxic Incubation and Priming Experiment in a Permafrost and Thermokarst Peatland in Lutose, Alberta, Canada
<p>The dataset presents anaerobic SOC mineralization results through incubations (CO2 and CH4 production rates) from a permafrost peat plateau and two adjacent thermokarst bogs which thawed ~30 (Young Thermokarst bog) and ~200 (Mature Thermokarst bog) years ago. Peat was incubated from 15 depths of ⁓6 m cores at 4 and 15°C for 714 days, followed by a priming experiment to assess the potential role of labile plant inputs on SOC mineralization.</p>
Data for "Paranormal experiences, sensory-processing sensitivity, and the priming of pareidolia".
<p>Data from a study investigating paranormal priming effects, the detection of voices in ambiguous stimuli, and the perceptual advantage of sensory-processing sensitivity. </p>
Parasite resistance and parasite tolerance: insights into transgenerational immune priming in an invertebrate host
<p>Parasites impose different selection regimes on their hosts, which respond by increasing their resistance and/or tolerance. Parental challenge with parasites can enhance the immune response of their offspring, a phenomenon documented in invertebrates and termed transgenerational immune priming. We exposed two parental generations of the model organism <em>Daphnia magna</em> to the horizontally-transmitted parasitic yeast <em>Metschnikowia bicuspidata</em>, and recorded resistance- and tolerance-related traits in the offspring generation. We hypothesized that parentally-primed offspring will increase either their resistance or their tolerance to the parasite. Our susceptibility assays revealed no impact of parental exposure on offspring resistance. Nonetheless, different fitness-related traits, which are indicative of tolerance, were altered. Specifically, maternal priming increased offspring production and decreased survival. Grandmaternal priming positively affected age at first reproduction and negatively affected brood size at first reproduction. Interestingly, both maternal and grandmaternal priming significantly reduced within-host parasite proliferation. Nevertheless, <em>Daphnia </em>primed for two consecutive generations had no competitive advantage in comparison to unprimed ones, implying additive maternal and grandmaternal effects. Our findings do not support evidence of transgenerational immune priming from bacterial infections in the same host species, thus emphasizing that transgenerational immune responses may not be consistent even within the same host species.</p>
All-atom molecular dynamics simulations of synaptic vesicle fusion I: a glimpse at the primed Synaptotagmin-SNARE-complexin complex
<p>Synaptic vesicles are primed into a state that is ready for fast neurotransmitter release upon Ca<sup>2+</sup>-binding to Syt1. This state likely includes trans-SNARE complexes between the vesicle and plasma membranes that are bound to Syt1 and complexins. However, the nature of this state and the steps leading to membrane fusion are unclear, in part because of the difficulty of studying this dynamic process experimentally. To shed light into these questions, we performed all-atom molecular dynamics simulations of systems containing trans-SNARE complexes between two flat bilayers or a vesicle and a flat bilayer with or without fragments of Syt1 and/or complexin-1. Our results need to be interpreted with caution because of the limited simulation times and the absence of key components, but suggest mechanistic features that may control release and help visualize potential states of the primed Syt1-SNARE-complexin-1 complex. In particular, the simulations suggest that SNAREs alone induce formation of extended membrane-membrane contact interfaces that may fuse slowly, and that the primed state contains macromolecular assemblies of trans-SNARE complexes bound to the Syt1 C<sub>2</sub>B domain and complexin-1 in a spring-loaded configuration that prevents premature membrane merger and formation of extended interfaces but keeps the system ready for fast fusion upon Ca<sup>2+</sup> influx.</p>
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.