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136 results for “quercetin”
Figure 3 from: Laksmiani NPL, Widiantara IWA, Pawarrangan ABS (2022) Potency of moringa (Moringa oleifera L.) leaves extract containing quercetin as a depigmentation agent inhibiting the tyrosinase enzyme using in-silico and in-vitro assay. Pharmacia 69(1): 85-92. https://doi.org/10.3897/pharmacia.69.e73132
Figure 3 The interaction of hydrogen bonds between the target protein of the tyrosinase with kojic acid. a: docking conformation kojic acid to tyrosinase, b: 3D interaction visualization of tyrosinase amino acid residues with kojic acid, c: 2D interaction visualization of tyrosinase amino acid residues with kojic acid.
Figure 5 from: Laksmiani NPL, Widiantara IWA, Pawarrangan ABS (2022) Potency of moringa (Moringa oleifera L.) leaves extract containing quercetin as a depigmentation agent inhibiting the tyrosinase enzyme using in-silico and in-vitro assay. Pharmacia 69(1): 85-92. https://doi.org/10.3897/pharmacia.69.e73132
Figure 5 TLC-chromatogram of Moringa Leaves extract at UV 254 nm (A) and UV 366 nm (B). Quercetin standard 100, 200, 400, 800, 1600 and 3200 ng (1–6); Moringa Leaves Maceration extract (7); reflux extract (8), soxhlation extract (9); quercetin standard 800 ng (10–11); UV spectrum of spot with Rf 0.4 from quercetin standard (C); UV spectrum of spot with Rf 0.4 from maceration extract of Moringa Leaves (D); UV spectrum of spot with Rf 0.4 from soxhlation extract of Moringa Leaves (E).
Figure 1 from: Laksmiani NPL, Widiantara IWA, Pawarrangan ABS (2022) Potency of moringa (Moringa oleifera L.) leaves extract containing quercetin as a depigmentation agent inhibiting the tyrosinase enzyme using in-silico and in-vitro assay. Pharmacia 69(1): 85-92. https://doi.org/10.3897/pharmacia.69.e73132
Figure 1 Redocking visualization between tyrosinase enzyme and native ligand. 1: The structure of the tyrosinase enzyme (PDB ID: 2Y9X), 2a: tyrosinase enzyme structure without native ligand, 2b: native ligand (tropolone) structure, 3a: redocking conformation, 3b: 3D interaction of amino acid residues from tyrosinase enzyme with native ligand, 3c: 2D interaction of amino acid residues from tyrosinase enzyme with native ligand.
Figure 4 from: Laksmiani NPL, Widiantara IWA, Pawarrangan ABS (2022) Potency of moringa (Moringa oleifera L.) leaves extract containing quercetin as a depigmentation agent inhibiting the tyrosinase enzyme using in-silico and in-vitro assay. Pharmacia 69(1): 85-92. https://doi.org/10.3897/pharmacia.69.e73132
Figure 4 The interaction of hydrogen bonds between the target protein of the tyrosinase with quercetin. a: docking conformation between quercetin and tyrosinase, b: 3D interaction visualization of tyrosinase amino acid residues with quercetin, c: 2D interaction visualization of tyrosinase amino acid residues with quercetin.
Figure 6 from: Laksmiani NPL, Widiantara IWA, Pawarrangan ABS (2022) Potency of moringa (Moringa oleifera L.) leaves extract containing quercetin as a depigmentation agent inhibiting the tyrosinase enzyme using in-silico and in-vitro assay. Pharmacia 69(1): 85-92. https://doi.org/10.3897/pharmacia.69.e73132
Figure 6 The regression curve of the relationship between AUC and series concentration of quercetin standard.
Relating Crystal Structure to Surface Properties: A Study on Quercetin Solid Forms
<p>This dataset was used in the publication "Relating Crystal Structure to Surface Properties: A Study on Quercetin Solid Forms". In this work, the surface properties of two different quercetin solvates (quercetin dihydrate and quercetin DMSO solvate) were studied using molecular (synthonic) modeling and experimental techniques, including inverse gas chromatography (IGC) and contact angle measurements, to establish a relationship between crystal structure and surface properties. The attachment energy model was used to predict morphologies and calculate surface properties through the study of their growth synthons. The modeling results confirmed the surface chemistry anisotropy for the two forms. For quercetin dihydrate, the {010} facets were found to grow mainly by nonpolar offset quercetin–quercetin stacking interactions, thus being hydrophobic, while the {100} facets were expected to be hydrophilic, growing by a polar quercetin–water hydrogen bond. For QDMSO, the dominant facet {002} grows by a strong polar quercetin–quercetin hydrogen bonding interaction, while the second most dominant facet {011} grows by nonpolar π–π stacking interactions. Water contact angle measurements and IGC confirmed a greater overall surface hydrophilicity for QDMSO compared to QDH and demonstrated surface energy heterogeneity for both structures. This work shows how synthonic modeling can help in the prediction of the surface nature of crystalline particles and guide the choice of parameters that will determine the optimal crystal form and final morphology for targeted surface properties, for example, the choice of crystallization conditions, choice of solvent, or presence of additives or impurities, which can direct the crystallization of a specific crystal form or crystal shape.</p>
research data for the paper The quercetin metabolite 4-methylcatechol causes vasodilation via voltage-gated potassium (KV) channels
<p>Research data for paper</p>
Figure 3 from: Demkovych A, Shcherba V, Yaremchuk O, Stoikevych H, Machogan V, Luchynskyi V (2021) Effects of flavonol quercetin on syndrome of endogenous intoxication in experimental periodontitis. Pharmacia 68(3): 627-632. https://doi.org/10.3897/pharmacia.68.e67341
Figure 3 Dynamics of erythrocyte intoxication index in the blood serum of white rats with experimental periodontitis with quercetin correction (in % of control). Notes: * – significant of differences in relation to the intact animals (p < 0.01); # – # – significant of differences in relation to the animals with periodontitis on the 7th day of experiment without correction (p < 0.05).
Figure 2 from: Demkovych A, Shcherba V, Yaremchuk O, Stoikevych H, Machogan V, Luchynskyi V (2021) Effects of flavonol quercetin on syndrome of endogenous intoxication in experimental periodontitis. Pharmacia 68(3): 627-632. https://doi.org/10.3897/pharmacia.68.e67341
Figure 2 Dynamics of content middle molecular weight molecules (280 nm) in the blood serum of white rats with experimental periodontitis with quercetin correction (in % of control). Notes: * – significant of differences in relation to the intact animals (p < 0.01); # – significant of differences in relation to the animals with periodontitis on the 7th day of experiment without correction (p < 0.05).
Figure 1 from: Demkovych A, Shcherba V, Yaremchuk O, Stoikevych H, Machogan V, Luchynskyi V (2021) Effects of flavonol quercetin on syndrome of endogenous intoxication in experimental periodontitis. Pharmacia 68(3): 627-632. https://doi.org/10.3897/pharmacia.68.e67341
Figure 1 Dynamics of content middle molecular weight molecules (254 nm) in the blood serum of white rats with experimental periodontitis with quercetin correction (in % of control). Notes: * – significant of differences in relation to the intact animals (p < 0.01); # – # – significant of differences in relation to the animals with periodontitis on the 7th day of experiment without correction (p < 0.05).
Effect of Quercetin in Treatment of Periodontitis
ClinicalTrials.gov study NCT05928546. IPD Sharing: NO. Countries: 0. Publications: 4.
Trial of Quercetin, Bromelain, Rye Flower Pollen & Papain on Reducing Severity of Radiation-Induced Prostatitis
ClinicalTrials.gov study NCT04252625. IPD Sharing: NO. Countries: 1. Publications: 0.
Quercetin Chemoprevention for Squamous Cell Carcinoma in Patients With Fanconi Anemia
ClinicalTrials.gov study NCT03476330. IPD Sharing: NO. Countries: 1. Publications: 0.
Data from: Anthracycline drugs on modified surface of quercetin-loaded polymer nanoparticles: a dual drug delivery model for cancer treatment
Open the record for dataset details and reuse information.
Senolytic and anti-inflammatory efficacy of quercetin in men and women undergoing coronary artery by-pass surgery
GEO Series GSE278420. Homo sapiens. 12 samples. Type: Expression profiling by high throughput sequencing.
Quercetin decreases high-fat diet induced bodyweight gain and accumulation of hepatic and circulating lipids in mice.
GEO Series GSE51343. Mus musculus. 21 samples. Type: Expression profiling by array.
Global gene expression analysis of quercetin bioactivity in cultured rat cardiomyocytes
GEO Series GSE7222. Rattus norvegicus. 6 samples. Type: Expression profiling by array.
Transcriptomic study identifies quercetin and rutin as repurposed drugs for Parkinson’s Disease in in vitro 6-OHDA model
GEO Series GSE198009. Homo sapiens. 16 samples. Type: Expression profiling by array.
miRNA expression profiling of murine LPS-stimulated dendritic cells exposed to quercetin
GEO Series GSE112327. Mus musculus. 16 samples. Type: Non-coding RNA profiling by high throughput sequencing.
Quercetin showed no genotoxicity by transcriptomic analysis in liver and small intestine of mice
GEO Series GSE63227. Mus musculus. 23 samples. Type: Expression profiling by array.
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