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146 results for “steady-state”
Getting the phase consistent: The importance of phase description in balanced steady-state free precession MRI of multi-compartment systems
<p>Experimental Data set of the Note: "Getting the phase consistent: The importance of phase description in balanced steady-state free precession MRI of multicompartment systems". <br>1) The folders "E1_..." and "E2_..." contain the bSSFP profiles </p><p>2) The folder "E3_..." contains the spectroscopic data obtained via the JMRUI software. </p><p>3) The folder "M_..." contains further details about the acetone-water phantom. </p>
Data from: Accounting for experimental noise reveals that mRNA levels, amplified by post-transcriptional processes, largely determine steady-state protein levels in yeast
Cells respond to their environment by modulating protein levels through mRNA transcription and post-transcriptional control. Modest observed correlations between global steady-state mRNA and protein measurements have been interpreted as evidence that mRNA levels determine roughly 40% of the variation in protein levels, indicating dominant post-transcriptional effects. However, the techniques underlying these conclusions, such as correlation and regression, yield biased results when data are noisy, missing systematically, and collinear---properties of mRNA and protein measurements---which motivated us to revisit this subject. Noise-robust analyses of 24 studies of budding yeast reveal that mRNA levels explain more than 85% of the variation in steady-state protein levels. Protein levels are not proportional to mRNA levels, but rise much more rapidly. Regulation of translation suffices to explain this nonlinear effect, revealing post-transcriptional amplification of, rather than competition with, transcriptional signals. These results substantially revise widely credited models of protein-level regulation, and introduce multiple noise-aware approaches essential for proper analysis of many biological phenomena.
The Effect of BIA 2-093 on the Steady-state Pharmacokinetics of Digoxin
ClinicalTrials.gov study NCT02172742. IPD Sharing: Not stated. Countries: 1. Publications: 0.
A Study to Investigate the Potential Interaction Between Telaprevir and Methadone, at Steady-State
ClinicalTrials.gov study NCT00933283. IPD Sharing: Not stated. Countries: 0. Publications: 1.
Evaluation of the Effect of Multiple Dosing With BI 201335 on CYP2B6 Metabolism and Effect of Multiple Dosing With Efavirenz on the Steady-state Pharmacokinetics of BI 201335 and on CYP3A4/5 Metabolis
ClinicalTrials.gov study NCT01371006. IPD Sharing: Not stated. Countries: 1. Publications: 0.
TMC125-TiDP2-C187: A Phase I, Open-label Trial to Investigate the Pharmacokinetic Interaction Between TMC125 and Two Antifungal Agents (Fluconazole and Voriconazole), All at Steady-state in Healthy Su
ClinicalTrials.gov study NCT00740389. IPD Sharing: Not stated. Countries: 0. Publications: 1.
Effect of Three Multiple-dose Regimens of BIA 9 1067 at Steady-state on the Levodopa Pharmacokinetics
ClinicalTrials.gov study NCT02169414. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Effect of BIA 9-1067 at Steady-state on the Pharmacokinetics of Levodopa/Carbidopa and Levodopa/Benserazide
ClinicalTrials.gov study NCT01533116. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Steady-state Pharmacokinetics of BIA 2-093 and Oxcarbazepine in Healthy Volunteers
ClinicalTrials.gov study NCT01679002. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Steady-State Pharmacokinetics of Rifaximin 550 mg Tablets in Healthy and Hepatically Impaired Subjects
ClinicalTrials.gov study NCT03818672. IPD Sharing: UNDECIDED. Countries: 1. Publications: 0.
Drug-Drug Interaction Study to Assess the Effects of Steady State Pitavastatin 4 mg or Rosuvastatin 40 mg on Steady-State Warfarin in Healthy Adult Volunteers
ClinicalTrials.gov study NCT01178853. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Effects of Pioglitazone on Exogenous Carbohydrate Oxidation During Steady-State Exercise at High Altitude
ClinicalTrials.gov study NCT06164665. IPD Sharing: NO. Countries: 1. Publications: 0.
The Effect of BIA 9-1067 at Steady-state on the Levodopa Pharmacokinetics
ClinicalTrials.gov study NCT02170376. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Single-dose and Steady-state Pharmacokinetics of BIA 2-093 and Its Metabolites
ClinicalTrials.gov study NCT02172755. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Data associated with manuscript "Predicting wave-induced sediment resuspension at the perimeter of lakes using a steady-state spectral wave model"
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Data from: Stepping in the direction of the fall: the next foot placement can be predicted from current upper body state in steady-state walking
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Investigation of damping effects on low-frequency steady-state acoustical behaviour of coupled spaces
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Data from: Accounting for experimental noise reveals that mRNA levels, amplified by post-transcriptional processes, largely determine steady-state protein levels in yeast
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Mitochondrial pyruvate metabolism and glutaminolysis toggle steady-state and emergency myelopoiesis
GEO Series GSE225578. Mus musculus. 10 samples. Type: Expression profiling by high throughput sequencing.
Differential Contribution of Steady-State RNA and Active Transcription in Chromatin Organization
GEO Series GSE114337. Homo sapiens. 12 samples. Type: Other.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.