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3,259 results for “type studies”
Crystallization and X-ray diffraction studies of a complete bacterial fatty-acid synthase type I
<p>These are X-ray diffraction data from the publication<br> Enderle, M.E, McCarthy, A, Paithankar, K. S, and Grininger, M</p> <p>Crystallization and X-ray diffraction studies of a complete bacterial fatty-acid synthase type I.</p> <p>Acta Crystallogr F Struct Biol Commun. 2015 Nov;71(Pt 11):1401-7</p> <p>CC-BY-SA license</p> <p>MD5SUMS</p> <p>a774aabcd316b5b200ef5c08b109ba9a crystal-form-II_part-1.tar.lzma</p> <p>3596da75621648cc0ac5ee84b26deab0 crystal-form-II_part-2.tar.lzma</p> <p>8a5410ce3178c814d7a127491e68ca0a crystal-form-I_part-1.tar.lzma</p> <p>259614e1b2cfe089141fb7baa846af7e crystal-form-I_part-2.tar.lzma</p>
Mapping breakpoint types: an exploratory study
<p>This repository contains the breakpoint types study dataset.</p> <p><strong>Abstract</strong></p> <p>Debugging is a relevant task for finding bugs during software development, maintenance, and evolution. During debugging, developers use modern IDE debuggers to analyze variables, step execution, and set breakpoints. Observing IDE debuggers, we find several breakpoint types. However, what are the breakpoint types? The goal of our study is to map the breakpoint types among IDEs and academic literature. Thus, we mapped the gray literature on the documentation of the nine main IDEs used by developers according to the three public rankings. In addition, we performed a systematic mapping of academic literature over 68 articles describing breakpoint types. Finally, we analyzed the developers understanding of the main breakpoint types through a questionnaire. We present three main contributions: (1) the mapping of breakpoint types (IDEs and literature), (2) compiled definitions of breakpoint types, (3) a breakpoint type taxonomy. Our contributions provide the first step to organize breakpoint IDE taxonomy and lexicon, and support further debugging research.</p>
A gene variation at the ZPR1 locus (rs964184) interacts with the type of diet to modulate postprandial triglycerides in patients with coronary artery disease: From the Cordioprev Study
<p>Background and Aims: rs964184 variant in the ZPR1 gene has been associated with blood lipids levels both in fasting and postprandial state and with the risk of myocardial<br>infarction in high-risk cardiovascular patients. However, whether this association is modulated by diet has not been studied.</p> <p>Objective: To investigate whether the type of diet (low-fat or Mediterranean diets) interacts with genetic variability at this loci to modulate fasting and postprandial lipids in<br>coronary patients.</p> <p>Materials and Methods: The genotype of the rs964184 polymorphism was determined in the Cordioprev Study population (NCT00924937). Fasting and Postprandial triglycerides were assessed before and after 3 years of dietary intervention with either a Mediterranean or a low-fat diet. Postprandial lipid assessment was done by a 4-h oral fat tolerance test (OFTT). Differences in triglycerides levels were identified using repeated-measures ANCOVA.</p> <p>Results: From 523 patients (85% males, mean age 59 years) that completed the OFTT at baseline and after 3 years of intervention and had complete genotype information, 125<br>of them were carriers of the risk allele G. At the start of the study, these patients showed a higher fasting and postprandial triglycerides (TG) plasma levels. After 3 years of dietary<br>intervention, G-carriers following a Mediterranean Diet maintained higher fasting and postprandial triglycerides, while those on the low-fat diet reduced their postprandial<br>triglycerides to similar values to the population without the G-allele.</p> <p>Conclusion: After 3 years of dietary intervention, the altered postprandial triglyceride response induced by genetic variability in the rs964184 polymorphism of the ZPR1 gene<br>can be modulated by a low-fat diet, better than by a Mediterranean diet, in patients with coronary artery disease.</p>
A computational study of the structure and function of human Zrt and Irt-like proteins metal transporters: An elevator-type transport mechanism predicted by AlphaFold2
<p>Data produced and analyzed in the manuscript "A computational study of the structure and function of human Zrt and Irt-like proteins metal transporters: An elevator-type transport mechanism predicted by AlphaFold2" by Pasquadibisceglie et al.</p> <p><br> If you include these data in your manuscript, please cite: Pasquadibisceglie A, Leccese A and Polticelli F (2022) A computational study of the structure and function of human Zrt and Irt-like proteins metal transporters: An elevator-type transport mechanism predicted by AlphaFold2. <em>Front. Chem.</em> 10:1004815. doi: 10.3389/fchem.2022.1004815</p>
Integration of molecular typing results_pilot Study_Germany
<p>This is the supporting data file for the manuscript entitled "Integration of molecular typing results into tuberculosis surveillance in Germany ─ a pilot study" (Andrés et al., PLoS ONE). The dataset includes anonymized, routinely collected notification data for 918 individuals. The data are published open-access, in accordance with the PLoS ONE data policy (2017).</p>
Multidimensional Parameter Study of Double Detonation Type Ia Supernovae Originating from Thin Helium Shell White Dwarfs
<p>This dataset provides the end-state ejecta data for each of the simulations from Boos et al. 2021, along with condensed versions for use in radiative transfer calculations.</p>
CMT1A-BioStampNPoint2023: Charcot-Marie-Tooth disease type 1A accelerometry dataset from three wearable sensor study
<p>The CMT1A-BioStampNPoint2023 dataset provides data from a wearable sensor accelerometry study conducted for studying gait, balance, and activity in 15 individuals with Charcot-Marie-Tooth disease Type 1A (CMT1A). In addition to individuals with CMT1A, the dataset also includes data for 15 controls that also went through the same in-clinic study protocol as the CMT1A participants with a substantial fraction (9) of the controls also participating in the in-home study protocol. For the CMT1A participants, data is provided for 15 participants for the baseline visit and associated home recording duration and, additionally, for a subset of 12 of these participants data is also provided for a 12-month longitudinal visit and associated home recording duration. For controls, no longitudinal data is provided as none was recorded. The data were acquired using lightweight MC 10 BioStamp NPoint sensors (MC 10 Inc, Lexington, MA), three of which were attached to each participant for gathering data over a roughly one day interval. For additional details, see the description in the "README.md" included with the dataset.</p>
Prospective cohort study of a community-based primary care program's effects on pharmacotherapy quality in low-income Peruvians with type 2 diabetes and hypertension
<p>A door-to-door survey was conducted to enumerate all household members by age and sex in a low-income community in Peru. 856 adults 35 years and older were eligible to participate in screening for type 2 diabetes and hypertension. 709 (83%) participated in screening. 130 (18.3%) were diagnosed with hypertension and/or type 2 diabetes of which 109 (84%) participated at program onset and 22 were added later from earlier non-participants in screening or program onset to form the cohort of 131 patients with diabetes and/or hypertension. The primary care program had components of the Chronic Care Model, community health workers, and freely accessible visits and medications. The program operated between September 2011 and May 2014, and consisted of two care periods (separated by a six-month hiatus), first a 10-month home-care period, then a 17-month clinic-care period. The dataset is two files corresponding to two exposures: the 27-month program overall (post- versus pre-) (N=262 observations, 131 pairs with patients as self-controls) and care period (clinic versus home), N=211 (109 home and 102 clinic observations, >131 because 80 patients participated in both care periods). Exposures were evaluated for their effects on guidelines-based pharmacotherapy standards: hypoglycemic and antihypertensive medications, low-dose aspirin, and first-line angiotensin converting enzyme inhibitor (ACEi) treatment of diabetes with elevated blood pressure.</p>
Study to Compare the Efficacy and Safety of Administration of the Fix Dose Combination of Linagliptin Plus Metformin in Drug naïve Type 2 Patients
ClinicalTrials.gov study NCT01708902. IPD Sharing: Not stated. Countries: 4. Publications: 1.
A Study to Evaluate the Dose Response Based on the Efficacy, Safety and Tolerability of Bimekizumab in Subjects With Active Psoriatic Arthritis Which is a Type of Inflammatory Arthritis
ClinicalTrials.gov study NCT02969525. IPD Sharing: Not stated. Countries: 6. Publications: 3.
A Study to Evaluate the Effect of Long-term Treatment With BELVIQ (Lorcaserin HCl) on the Incidence of Major Adverse Cardiovascular Events and Conversion to Type 2 Diabetes Mellitus in Obese and Overw
ClinicalTrials.gov study NCT02019264. IPD Sharing: Not stated. Countries: 8. Publications: 4.
A Study to Determine the Safety and Efficacy of NT-501 in Macular Telangiectasia Type 2 - Protocol B
ClinicalTrials.gov study NCT03319849. IPD Sharing: NO. Countries: 3. Publications: 1.
A Study to Evaluate the Glycemic Effects, Safety, and Tolerability of Exenatide Once Weekly in Subjects With Type 2 Diabetes Mellitus (DURATION-5)
ClinicalTrials.gov study NCT00877890. IPD Sharing: Not stated. Countries: 1. Publications: 5.
A Phase I Study of Quadrivalent Human Papilloma Virus (HPV) (Types 6, 11, 16, 18) Recombinant Vaccine in HIV-Infected and HIV-Negative Pre-Adolescents, Adolescents, and Young Adults
ClinicalTrials.gov study NCT00798265. IPD Sharing: YES. Countries: 1. Publications: 3.
An Observational Study Evaluating SYMLIN® (Pramlintide Acetate) Injection Use in Insulin Using Patients With Type 2 and Type 1 Diabetes
ClinicalTrials.gov study NCT00229658. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Feasibility Study on the Impact of Economic Incentives to Improve the Management of Type 2 Diabetes Mellitus
ClinicalTrials.gov study NCT02891382. IPD Sharing: YES. Countries: 1. Publications: 2.
A Study of BMS-512148 (Dapagliflozin) in Patients With Type 2 Diabetes With Inadequately Controlled Hypertension on an ACEI or ARB and an Additional Antihypertensive Medication
ClinicalTrials.gov study NCT01195662. IPD Sharing: Not stated. Countries: 16. Publications: 2.
MiniMed™ 670G System China Study for Type I Diabetic
ClinicalTrials.gov study NCT04663295. IPD Sharing: NO. Countries: 1. Publications: 1.
A Study to Compare the Glycemic Effects, Safety, and Tolerability of Exenatide Once Weekly to Those of Sitagliptin and Pioglitazone,in Subjects With Type 2 Diabetes Treated With Metformin (DURATION -
ClinicalTrials.gov study NCT00637273. IPD Sharing: Not stated. Countries: 3. Publications: 8.
Long-term Open-label Study of Botulinumtoxin Type A to Treat Spasticity of Leg(s) or Leg(s) and Arm in Cerebral Palsy
ClinicalTrials.gov study NCT01905683. IPD Sharing: Not stated. Countries: 12. Publications: 1.
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.