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76 results for “unpredictability”
Data from: Escherichia coli populations in unpredictably fluctuating environments evolve to face novel stresses through enhanced efflux activity
There is considerable understanding about how laboratory populations respond to predictable (constant or deteriorating environment) selection for single environmental variables such as temperature or pH. However, such insights may not apply when selection environments comprise multiple variables that fluctuate unpredictably, as is common in nature. To address this issue, we grew replicate laboratory populations of Escherichia coli in nutrient broth whose pH and concentrations of salt (NaCl) and hydrogen peroxide (H2O2) were randomly changed daily. After ~170 generations, the fitness of the selected populations had not increased in any of the three selection environments. However, these selected populations had significantly greater fitness in four novel environments which have no known fitness-correlation with tolerance to pH, NaCl or H2O2. Interestingly, contrary to expectations, hypermutators did not evolve. Instead, the selected populations evolved an increased ability for energy-dependent efflux activity that might enable them to throw out toxins, including antibiotics, from the cell at a faster rate. This provides an alternate mechanism for how evolvability can evolve in bacteria and potentially lead to broad-spectrum antibiotic resistance, even in the absence of prior antibiotic exposure. Given that environmental variability is increasing in nature, this might have serious consequences for public health.
Data from: Unpredictable movement as an anti-predator strategy
Prey animals have evolved a wide variety of behaviours to combat the threat of predation, and these have been generally well studied. However, one of the most common and taxonomically widespread antipredator behaviours of all has, remarkably, received almost no experimental attention: so-called 'protean' behaviour. This is behaviour which is sufficiently unpredictable to prevent a predator anticipating in detail the future position or actions of its prey. In this study, we used human 'predators' participating in 3D virtual reality simulations to test how protean (i.e. unpredictable) variation in prey movement affects participants' ability to visually target them as they move (a key determinant of successful predation). We found that targeting accuracy was significantly predicted by prey movement path complexity, although, surprisingly, there was little evidence that high levels of unpredictability in the underlying movement rules equated directly to decreased predator performance. Instead, the specific movement rules differed in how they impacted on targeting accuracy, with the efficacy of protean variation in one element depending on the values of the remaining elements. These findings provide important insights into the understudied phenomenon of protean antipredator behaviour, which are directly applicable to predator-prey dynamics within a broad range of taxa.
Unleashing Unpredictability: The Batman Project and Its Impact on Prosocial Behavior and Awareness
ClinicalTrials.gov study NCT06481748. IPD Sharing: NO. Countries: 0. Publications: 1.
Data from: Glucocorticoid response to both predictable and unpredictable challenges detected as corticosterone metabolites in collared flycatcher droppings
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Data from: Escherichia coli populations adapt to complex, unpredictable fluctuations by minimizing trade-offs across environments
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Data from: Moving in groups: how density and unpredictable motion affect predation risk
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Data from: Unpredicted impacts of insect endosymbionts on interactions between soil organisms, plants and aphids
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Data from: Unpredictable perturbation reduces breeding propensity regardless of pre-laying reproductive readiness in a partial capital breeder
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Data from: Escherichia coli populations in unpredictably fluctuating environments evolve to face novel stresses through enhanced efflux activity
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Data from: Extent of adaptation is not limited by unpredictability of the environment in laboratory populations of Escherichia coli
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Data from: Unpredictable movement as an anti-predator strategy
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Data from: Experimental evolution of bet hedging in rotifer diapause traits as a response to environmental unpredictability
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Data from: Species-specific strategies increase unpredictability of escape flight in eared moths
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Data from: Predictable males and unpredictable females: repeatability of sociability in eastern water dragons
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Data from: Prenatal stress effects in a wild, long-lived primate: predictive adaptive responses in an unpredictable environment
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Long-term measures of climate unpredictability shape the avian endocrine stress axis
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Long-term multi-modal recording reveals unpredictable nongenetic adaptation routes in dormant breast cancer cells. [WGS]
GEO Series GSE234173. Homo sapiens. 117 samples. Type: Genome variation profiling by high throughput sequencing.
An antisense oligomer conjugate with unpredicted bactericidal activity against Fusobacterium nucleatum
GEO Series GSE284320. Fusobacterium nucleatum. 36 samples. Type: Expression profiling by high throughput sequencing.
Data from: Spatial and temporal unpredictability of colony size in cliff swallows across 30 years
Most colonially breeding animals occupy colonies that range in size from a few pairs to thousands of individuals, but the causes of colony size variation are largely unknown. Three general hypotheses are: (1) that variation in colony size is maintained by fluctuating selection via spatial and temporal changes in fitness associated with different colony sizes; (2) that colony formation reflects heterogeneity in habitat, with some sites having resources to support more individuals than others; and (3) that individuals assess the presence or annual reproductive success of current colony residents at each site and aggregate preferentially at high-quality sites. These hypotheses make predictions about how consistent colony size should be across sites and among years. We examined temporal and spatial variability of colony size for >200 Cliff Swallow (Petrochelidon pyrrhonota) colony sites in western Nebraska across a 30-year period. A colony's substrate type, annual population size in the study area, and whether the nesting season was relatively warm or cool, influenced average annual colony size. While some Cliff Swallow colony sites hosted perennially large colonies and others perennially small ones, between-year variability in colony size at most sites was high. Annual colony size distributions were relatively stable over 30 years and provided no evidence for long-term directional changes in colony size. The only ecological characteristic that was strongly associated with Cliff Swallow colony size at a site was the type of nesting substrate, with bridges tending to have larger colonies and being more frequently occupied than other substrates. Some sites showed annual changes in colony size consistent with the birds' basing their choice of colony on the presence or success of conspecifics, but many sites did not conform to a pattern expected if coloniality is a by-product of traditional aggregation. Colony size in Cliff Swallows was temporally and spatially unpredictable when viewed across the 30 years of this study. Each of the three hypotheses to explain size variation may have applied at certain sites, but the pattern of colony size variability leant the most support to the hypothesis that fluctuating selection on group size maintains colonies of widely different sizes.
Assessing the Impact of Perceptions of Unpredictability on Objective Measures of Food Consumption and Metabolism
ClinicalTrials.gov study NCT06690294. IPD Sharing: NO. Countries: 1. Publications: 0.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.