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51 results for “virulence evolution”
Data from: Coevolution between mutualists and parasites in symbiotic communities may lead to the evolution of lower virulence
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Data from: Evolution of virulence in heterogeneous host communities under multiple trade-offs
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Data from: Virulence evolution of a generalist plant virus in a heterogeneous host system
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The CovR regulatory network drives the evolution of Group B Streptococcus virulence
GEO Series GSE158049. Streptococcus agalactiae. 40 samples. Type: Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by high throughput sequencing.
Chemical warfare does not always win – rapid evolution of increased virulence in Beauveria bassiana
GEO Series GSE71570. Beauveria bassiana. 28 samples. Type: Expression profiling by high throughput sequencing.
Convergent evolution of peptide-based quorum sensing required for virulence in a eukaryotic pathogen
GEO Series GSE73203. Cryptococcus neoformans. 47 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.
Data from: Expression of parasite genetic variation changes over the course of infection: implications of within-host dynamics for the evolution of virulence
How infectious disease agents interact with their host changes during the course of infection and can alter the expression of disease-related traits. Yet by measuring parasite life-history traits at one or few moments during infection, studies have overlooked the impact of variable parasite growth trajectories on disease evolution. Here we show that infection-age-specific estimates of host and parasite fitness components can reveal new insight into the evolution of parasites. We do so by characterizing the within-host dynamics over an entire infection period for five genotypes of the castrating bacterial parasite Pasteuria ramosa infecting the crustacean Daphnia magna. Our results reveal that genetic variation for parasite-induced gigantism, host castration and parasite spore loads increases with the age of infection. Driving these patterns appears to be variation in how well the parasite maintains control of host reproduction late in the infection process. We discuss the evolutionary consequences of this finding with regard to natural selection acting on different ages of infection and the mechanism underlying the maintenance of castration efficiency. Our results highlight how elucidating within-host dynamics can shed light on the selective forces that shape infection strategies and the evolution of virulence.
Data from: Expression of parasite genetic variation changes over the course of infection: implications of within-host dynamics for the evolution of virulence
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Evolution of virulence control by the staphylococcal agr quorum-sensing regulator
GEO Series GSE10165. Coxiella burnetii; Rickettsia rickettsii; Staphylococcus aureus; Staphylococcus epidermidis ATCC 12228; Chlamydia caviae GPIC; Borreliella burgdorferi B31; Chlamydia trachomatis D/UW-3/CX; Staphylococcus haemolyticus JCSC1435; Chlamydia pneumoniae AR39; Coxiella burnetii RSA 493; Granulibacter bethesdensis; Chlamydia muridarum; Staphylococcus epidermidis RP62A; Staphylococcus aureus subsp. aureus MW2. 27 samples. Type: Expression profiling by array.
Lineage-specific selection and the evolution of virulence in Candida albicans
GEO Series GSE168112. Candida albicans x Candida dubliniensis; Candida dubliniensis. 24 samples. Type: Expression profiling by high throughput sequencing.
Assessing the Evolution of Virulence in the Salmon Louse (Lepeophtheirus salmonis) in the Bay of Fundy
GEO Series GSE295072. Lepeophtheirus salmonis; Salmo salar. 94 samples. Type: Expression profiling by high throughput sequencing.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.