Find research datasets worth reusing
Search datasets from major research repositories and use ShareScore to quickly assess how well each record supports discovery, access, and reuse.
854
datasets available to search
ShareScore release 0.9.0
Dataset results
854 results for “Disparity”
Single-cell Transcriptomic Analysis Reveals Disparate Effector Differentiation Pathways in Human Treg Compartment [Treg patients]
GEO Series GSE175603. Homo sapiens. 18 samples. Type: Expression profiling by high throughput sequencing.
Combinatorial transcriptional profiling of mouse and human enteric neurons identifies shared and disparate subtypes in situ [Human Enteric Ganglia]
GEO Series GSE153198. Homo sapiens. 138 samples. Type: Expression profiling by high throughput sequencing.
Combinatorial transcriptional profiling of mouse and human enteric neurons identifies shared and disparate subtypes in situ
GEO Series GSE153202. Homo sapiens; Mus musculus. 166 samples. Type: Expression profiling by high throughput sequencing.
Replicative history marks transcriptional and functional disparity in the memory T cell pool
GEO Series GSE169154. Mus musculus. 2 samples. Type: Expression profiling by high throughput sequencing.
Failure of digit tip regeneration in the absence of Lmx1b suggests Lmx1b functions disparate from dorsoventral polarity
GEO Series GSE202223. Mus musculus. 10 samples. Type: Expression profiling by high throughput sequencing.
Single-cell RNA-seq reveals disparate macrophage responses to intracellular Salmonella
GEO Series GSE79363. Mus musculus. 60 samples. Type: Expression profiling by high throughput sequencing.
Differential Expression of miRNAs: Implication in Colon Cancer Racial Health Disparity
GEO Series GSE48267. Homo sapiens. 122 samples. Type: Non-coding RNA profiling by array.
Sex disparities in influenza: a multiscale network analysis (Female ferrets)
GEO Series GSE168511. Mustela putorius furo. 116 samples. Type: Expression profiling by high throughput sequencing.
Effect of fructose on human colon DNA methylation: implication for racial disparities in colorectal cancer risk
GEO Series GSE261717. Homo sapiens. 10 samples. Type: Expression profiling by high throughput sequencing.
Uncovering the role admixture in health disparities: Association of hepatocyte gene expression and DNA methylation to African Ancestry in African-Americans
GEO Series GSE124076. Homo sapiens. 567 samples. Type: Methylation profiling by array; Expression profiling by high throughput sequencing; Genome variation profiling by SNP array.
Data from: Clade-age-dependent diversification under high species turnover shapes species richness disparities among tropical rainforest lineages of Bulbophyllum (Orchidaceae)
Background: Tropical rainforests (TRFs) harbour almost half of the world's vascular plant species diversity while covering only about 6–7% of land. However, why species richness varies amongst the Earth's major TRF regions remains poorly understood. Here we investigate the evolutionary processes shaping continental species richness disparities of the pantropical, epiphytic and mostly TRF-dwelling orchid genus Bulbophyllum (c. 1,948 spp. in total; Asia-Pacific region: c. 1,564 spp.; Madagascar: 210; Africa: 80; Neotropics: 94) using diversification analyses based on a time-calibrated molecular phylogeny, coupled with ecological niche modelling (ENM) of geographic distributions under present and past (Last Glacial Maximum) conditions. Results: Our results suggest an early-to-late Miocene scenario of 'out-of-Asia-Pacific' origin and progressive, dispersal-mediated diversification in Madagascar, Africa and the Neotropics, respectively. Species richness disparities amongst these four TRF lineages are best explained by a time-for-speciation effect rather than differences in net diversification or diversity-dependent diversification due to present or past spatial-bioclimatic limits. All four lineages of experienced dramatic range expansions during the LGM, which conflicts with the common notion that TRFs mostly fragmented/contracted during glacial periods. Conclusions: Most species of at least the Madagascan, African and Neotropical lineages originated during the Quaternary. Their diversification under high species turnover (i.e. high rates of speciation and extinction) might relate to climate-induced range fluctuations during this time period combined with various intrinsic features commonly invoked to foster rapid population turnover in tropical orchids (e.g., epiphytism, specialization on pollinators and mycorrhizal fungi, dispersal by wind). Further (e.g., phylogenomic and ecological) research within each Bulbophyllum lineage but also other pantropical TRF taxa is required to provide a better understanding of how evolutionary processes as well as past and current environmental conditions drive tropical biodiversity and account for regional differences in species richness patterns on a global scale.
Data from: Eutherian morphological disparity across the end-Cretaceous mass extinction
In the aftermaths of mass extinction events, during radiations of clades, and in several other evolutionary scenarios, there is often a decoupling of taxonomic diversity and morphological disparity. The placental mammal radiation after the end-Cretaceous mass extinction is one of the archetypal adaptive radiations, but the change in morphological disparity of the entire skeleton has never been quantified across this important boundary. We reconstruct ancestral morphologies of 680 discrete morphological characters onto dated phylogenies of 177 mostly Cretaceous and Palaeogene eutherians (placental mammals and their stem relatives). Using a new approach to incorporate morphologies representing ghost lineages, we assess three measures of morphological disparity (sum of ranges, sum of variances and mean pairwise dissimilarity) across stage-level time bins within the Cretaceous and Palaeogene. We find that the range-based metric suggests that eutherian disparity increased immediately after the end-Cretaceous mass extinction, while both variance-based metrics declined from the Campanian to the Maastrichtian, but showed no change in disparity from the Maastrichtian to the Puercan – the first North American Land Mammal Age of the Paleocene. Increases in variance-based metrics lag behind the range-based metric and per-lineage accumulation rate, suggesting that the response of mammals to the Cretaceous–Palaeogene event was characterized by an early radiation that increased overall morphospace occupation, followed later by specialization that resulted in increased dissimilarity.
Data from: The role of preservation on the quantification of morphology and patterns of disparity within Paleozoic echinoderms
The loss of information resulting from taphonomic degradation could represent a significant bias in the study of morphological diversity. This potential bias is even more concerning given the uneven effect of taphonomy across taxonomic groups, depositional facies, and stratigraphic successions and in response to secular changes through the Phanerozoic. The effect of taphonomic degradation is examined using character-based morphological data sets describing disparity in Paleozoic crinoids and blastozoans. Characters were sequentially excluded from the analyses following progressive taphonomic loss to determine how morphologic metrics, such as the relative distribution of taxa in morphospace and partial disparity, changed with increasing taphonomic alteration. Blastozoans showed very little change in these metrics with decreasing preservational quality, which is a result of characters that create distance in morphospace being recognizable in isolated plates. The opposite result is present in crinoids as the characters that are important in structuring the morphospace require intact modules (i.e., the calyx) to accurately assess. Temporal and stratigraphic trends produced encouraging results in that patterns could be largely recovered even with exaggerated taphonomic biases. However, certain parts of a stratigraphic sequence should be avoided and morphological outliers could potentially play a larger role through time, though both of these biases can be easily identified and avoided. The methods presented in this study provide a way to assess potential taphonomic biases in character-based studies of morphological diversity.
Sex disparities in clinical features and burden of narcolepsy type 1
<p><span>To investigate potential sex-related differences in patients with <span>narcolepsy type 1 (NT1), we carried out an analysis of baseline data from 93 women and 89 men with NT1 who participated in the TElemedicine for NARcolepsy (TENAR) trial. The following data were considered: sociodemographics, diagnostic (disease history, polysomnography, orexin, HLA) and clinical features including sleepiness (Epworth Sleepiness Scale, ESS), cataplexy and other narcolepsy symptoms, disease severity (Narcolepsy Severity Scale, NSS), pharmacological treatment, depressive symptoms (Beck Depression Inventory, BDI), and self-reported relevance of 8 narcolepsy-related issues. We found that, compared with men, significantly more women reported automatic behaviors (55.4% vs. 40%) and had higher ESS (median 10 vs. 9) and BDI scores (median 10.5 vs. 5), and there was a trend for a higher NSS total score in women (median 19 vs. 18, p=0.057). More women than men were officially recognized as having a disability (38% vs. 22.5%) and considered 5/8 narcolepsy-related issues investigated as a relevant problem. More severe sleepiness and a greater narcolepsy-related burden in women could mirror sex differences present in the general population, or may be related to suboptimal management of NT1 or to more severe depressive symptoms in women. </span>Future studies and guidelines should address these aspects.<span> </span></span></p>
Data and code for 'Global disparity in synergy of solar power and vegetation growth'
<p>The 'stepwisefit' requires Statistics and Machine Learning Toolbox installed in the MATLAB to run the code. The import data are attached.</p>
Fig. 1 in Morphological disparity in Plio-Pleistocene large carnivore guilds from Italian peninsula
Fig. 1. Landmark configuration on a mandible of Canis lupus, BMNH 34.6.28.47.
Fig. 2 in Morphological disparity in Plio-Pleistocene large carnivore guilds from Italian peninsula
Fig. 2. Plot of the first three RWs in a subset of 57 mandibular corpus data of large carnivores.
Figure 2 from: Joseph P (2018) Eliminating disparities and implicit bias in health care delivery by utilizing a hub-and-spoke model. Research Ideas and Outcomes 4: e26370. https://doi.org/10.3897/rio.4.e26370
Figure 2 Colorectal cancer mortality rates during implementation of the nurse navigator system.
Figure 1 from: Joseph P (2018) Eliminating disparities and implicit bias in health care delivery by utilizing a hub-and-spoke model. Research Ideas and Outcomes 4: e26370. https://doi.org/10.3897/rio.4.e26370
Figure 1 Disparity in LDL cholesterol testing between black and white populations.
Scheffe Test Results for Educational Disparities in Parental Views on Family's Role in Preventing GBV
<p><strong><span>Scheffe Test Results for Educational Disparities in Parental Views on Family’s Role in Preventing GBV</span></strong></p>
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.