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846 results for “Homologization”
Comparative immunogenicity and reactogenicity of heterologous ChAdOx1 nCoV-19-priming and BNT162b2 or mRNA-1273-boosting with homologous COVID-19 vaccine regimens
<p>Multiple formulations and technologies for vaccinating against SARS-CoV-2 exist but how the use of these in homologous or heterologous format impacts immunogenicity is far from clear. Here the authors compare a range of heterologous and homologous SARS-CoV-2 vaccination strategies and assess the induced humoral and cellular immune response.</p> <p>The following heterologous and homologous vaccination regimens were tested for immunogenicity and reactogenicity in a in a convenience cohort of 331 healthy individuals. </p> <p>ChAdOx1-nCoV-19 followed by BNT162b2 (n=66)</p> <p>ChAdOx1-nCoV-19 followed by mRNA-1273 (n=101)</p> <p>BNT162b2 followed by BNT162b2 (n=43)</p> <p>mRNA-1273 followed by mRNA-1273 (n=59)</p> <p>ChAdOx1-nCoV-19 followed by ChAdOx1-nCoV-19 (n=62)</p>
Olaparib and ASTX727 in BRCA1/2- and Homologous Recombination Deficient (HRD)-Mutated Tumors
ClinicalTrials.gov study NCT06177171. IPD Sharing: NO. Countries: 1. Publications: 0.
Fluzoparib in Combination With or Without Camrelizumab for Homologous Recombinant Deficiency (HRD) HER2 Negative Advanced Breast Cancer
ClinicalTrials.gov study NCT05656131. IPD Sharing: NO. Countries: 1. Publications: 0.
A Study of Radspherin® in Patients With Primary Advanced Epithelial Cancer, With Peritoneal Metastasis That Are Homologous Recombination Proficient Scheduled to Undergo Neoadjuvant Chemotherapy and In
ClinicalTrials.gov study NCT06504147. IPD Sharing: Not stated. Countries: 6. Publications: 0.
Study to Investigate the Treatment Benefit of Probiotic Lactobacillus Crispatus M247 in Women Undergoing Homologous Level 2 Assisted Reproductive Technology (ART) Procedures
ClinicalTrials.gov study NCT05871242. IPD Sharing: Not stated. Countries: 1. Publications: 0.
A Safety and Immunogenicity Study of Heterologous and Homologous Prime-Boost Ebola Vaccine Regimens in Healthy Participants
ClinicalTrials.gov study NCT02325050. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Docetaxel, Carboplatin, and Rucaparib Camsylate in Treating Patients With Metastatic Castration Resistant Prostate Cancer With Homologous Recombination DNA Repair Deficiency
ClinicalTrials.gov study NCT03442556. IPD Sharing: NO. Countries: 1. Publications: 0.
Niraparib Plus Carboplatin in Patients With Homologous Recombination Deficient Advanced Solid Tumor Malignancies
ClinicalTrials.gov study NCT03209401. IPD Sharing: NO. Countries: 1. Publications: 0.
Senaparib in mCRPC Patients With Homologous Recombination Repair Gene Alterations After Docetaxel Treatment
ClinicalTrials.gov study NCT04822961. IPD Sharing: NO. Countries: 3. Publications: 0.
Effect of Gonadotropin Types and Indications on Homologous Intrauterine Insemination Success
ClinicalTrials.gov study NCT03669276. IPD Sharing: NO. Countries: 0. Publications: 0.
Detection of the Emergence of RAS (Rat Sarcoma Viral Oncogene Homolog) Mutations in Circulating DNA (Deoxyribonucleic Acid) in Patients With mCRC (Metastatic Colorectal Cancer) During Treatment With A
ClinicalTrials.gov study NCT03908788. IPD Sharing: NO. Countries: 1. Publications: 0.
Efficacy of Talazoparib in Asian Metastatic Breast Cancer Patients With a Homologous Recombinant Deficiency (HRD) Signature
ClinicalTrials.gov study NCT05288127. IPD Sharing: Not stated. Countries: 1. Publications: 0.
QL1706 With Olaparib for Previously Treated HER2-negative Breast Cancer Patients With Homologous Recombination Deficiency (HRD)
ClinicalTrials.gov study NCT07113964. IPD Sharing: NO. Countries: 1. Publications: 0.
Distribution of the Homologous Recombination-related (HRR) Genesmutationsand HRD in Breast Cancer
ClinicalTrials.gov study NCT05466786. IPD Sharing: NO. Countries: 1. Publications: 0.
Efficacy of Olaparib in Advanced Cancers Occurring in Patients With Germline Mutations or Somatic Tumor Mutations in Homologous Recombination Genes
ClinicalTrials.gov study NCT03967938. IPD Sharing: NO. Countries: 1. Publications: 0.
Phase II Study of Olaparib and Pembrolizumab in Advanced Melanoma With Homologous Recombination (HR) Mutation
ClinicalTrials.gov study NCT04633902. IPD Sharing: NO. Countries: 1. Publications: 0.
Clinical Study of QL1706 in Combination With Olaparib for the Treatment of Patients With Previously Treated Homologous Recombination Repair-Deficient Recurrent or Metastatic Triple-Negative Breast Can
ClinicalTrials.gov study NCT07005583. IPD Sharing: NO. Countries: 1. Publications: 0.
The Efficacy and Safety of Fluzoparib Plus Irinotecan as Second-line Treatment in Patients With Homologous Recombination Deficiency (HRD) Metastatic Colorectal Cancer.
ClinicalTrials.gov study NCT05732129. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Combination Therapy of Senaparib and Bevacizumab for First-line Maintenance Therapy in Newly Diagnosed Advanced Homologous Recombination Proficient Ovarian Cancer Based on Exosome Protein Marker
ClinicalTrials.gov study NCT07120451. IPD Sharing: UNDECIDED. Countries: 1. Publications: 0.
Characterization of Epithelial Ovarian Cancer Patients in Terms of Homologous Recombination Phenotype
ClinicalTrials.gov study NCT05574673. IPD Sharing: Not stated. Countries: 1. Publications: 0.
ScienceDex guides
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.