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Supporting code and data to reproduce analysis for: Genomic signatures of past megafrugivore-mediated dispersal in Malagasy palms
<p>Seed dispersal affects gene flow and hence genetic differentiation of plant populations. During the Late Quaternary, most fruit-eating and seed-dispersing megafauna went extinct, but whether these animals have left signatures in the population genetics of their food plants, particularly those with large, 'megafaunal' fruits (i.e., > 4 cm – megafruits), remains unclear.</p> <p>Here, we assessed the population history, genetic differentiation, and recent migration among populations of four animal-dispersed palm (Arecaceae) species with large (<em>Borassus madagascariensis</em>), medium-sized (<em>Hyphaene coriacea,</em> <em>Bismarckia nobilis</em>), and small (<em>Chrysalidocarpus madagascariensis</em>) fruits on Madagascar. We integrated double-digest restriction-site-associated DNA sequencing (ddRAD) of 167 individuals from 25 populations with (past) distribution ranges for extinct and extant seed-dispersing animals (e.g., giant lemurs, elephant birds), landscape and human impact data, and applied linear mixed-effects models to explore the drivers of genetic variation in Malagasy palms.</p> <p>Palm populations that shared more megafrugivore species in the past had lower genetic differentiation than populations that shared fewer megafrugivore species. This suggests that megafrugivore-mediated seed dispersal in the past may have led to frequent gene flow among populations. In comparison, extant frugivore diversity only decreased genetic differentiation in the small-fruited palm. Furthermore, genetic differentiation decreased with landscape connectivity (i.e., environmental suitability, forest cover and river density), and human impact (i.e., road density) has decreased genetic differentiation among populations.</p> <p><em>Synthesis: </em>Our results suggest that the legacy of megafrugivores regularly achieving long dispersal distances is still reflected in the population genetics of palms that were formerly dispersed by such animals. Furthermore, low genetic differentiation was possibly maintained after the megafauna extinctions through alternative dispersal (e.g., human- or river-mediated), long generation times, and long lifespans of these megafruit palms. Our study illustrates how species interactions that happened >1000 years ago can leave imprints in population genetics.</p>
Data supporting the manuscript entitled: 'Intermittent soil water stress history favors microbial traits that better mitigate wheat biomass losses during subsequent water stress.'
<p>Data living in this data repository supports the scientific article entitled: Intermittent soil water stress history favors microbial traits that better mitigate wheat biomass losses during subsequent water stress.</p> <p> </p> <p> </p> <p> </p>
Lidar Scans of the White River near Worthington, Indiana, U.S.A.: Supporting data for Martin et al. (2024)
<p>Supporting data for the manuscript "Four years of meander-bend evolution captured by drone-based lidar reveals lack of width maintenance on the White River, Indiana, USA" by Harrison K Martin, Douglas A Edmonds, and Quinn W Lewis. As of June 2024, the manuscript has been published in the <em>Journal of Geophysical Research: Earth Surface</em> and is available here: <a href="https://doi.org/10.1029/2023JF007574">https://doi.org/10.1029/2023JF007574</a>. You can find additional details in the Supplemental Information for that paper.</p> <p>Also of interest may be another recently published manuscript (in <em>Earth Surface Processes and Landforms</em>) on a pair of failed dams from central Michigan where we quantified topographic change using lidar change detection. On that study, we compared an airborne pre-flood survey to three post-flood drone-based lidar surveys we collected. The methods employed were not identical to this study (namely, there we used a point cloud to point cloud differencing method rather than the differences of DEMs used here), but there could be some helpful information in that manuscript's Supporting Info. It's available here: <a href="https://doi.org/10.1002/esp.5855">https://doi.org/10.1002/esp.5855</a>.</p> <p> </p> <p>In this repository you will find 22 bare-earth Digital Elevation Models (DEMs) of a single river bend on the meandering White River near Worthington, IN. The scans were collected over a period of ~4.5 years between April 2018 and November 2022 -- not coincidentally, nearly the same span of time as my PhD. Each DEM attempts to present the bare earth as if the vegetation were not present; the algorithms and trimming do a better job on tall, forested canopies (such as the northeastern-most part of the point bar) than on short, dense, shrubby grasses (such as certain parts of the cutbank or where crops were grown). The vegetation noise and artifacts will be the greatest in the summer months and the least in the winter. The point bar surface was always well-resolved. The actual river/water surface itself was masked out manually for each of the 22 scans, with null values defined for these and other no-data areas. The filename of each scan describes the date of collection. The cell size for each raster is 25 cm and was created by exporting a triangular lattice constructed from a ground-classified point cloud with a maximum length of 10 meters. Because of this, areas with very low point density (such as the outer boundaries of each scan, outside of the areas where we wanted to measure geomorphic changes) appear to be made of large triangles, and should not be trusted. The CRS for each is NAD83 / UTM zone 16N [https://epsg.io/26916].</p> <p> </p> <p>Please do not hesitate to reach out with any questions, requests, etc! I'm pretty responsive by email (hkm@caltech.edu) and website form (https://harrison.studies.rocks). If you have any questions about the methods, setting up your own drone-based lidar program, or are struggling with some of the arcane software and quirks of this sort of workflow... there is a chance that I've struggled through it before and am happy to share whatever I have learned!</p> <p> </p> <p>Thanks for stopping by!</p> <p> </p> <p>Acknowledgements:</p> <p>A big thanks is owed to Steve Scott of Indiana University, our stalwart drone pilot without whom none of this would have been possible. HKM was supported by National Aeronautics and Space Administration (NASA) Future Investigators in NASA Earth and Space Science and Technology (FINESST) grant 80NSSC21K1598 and a California Institute of Technology Geological and Planetary Sciences Geology Option Postdoctoral position. DAE was supported by National Sciences Foundation grant EAR-2321056. QWL was supported by a University of Waterloo New Faculty Starter Grant. All authors were supported by the Environmental Resilience Institute, funded by Indiana University’s Prepared for Environmental Change Grand Challenge initiative.</p> <p> </p> <p>UPDATES: <br>- 2024-04-29: Added Supporting Tables S1-S6.<br>- 2024-05-04: Updated some column headers in Supporting Tables S1-S6.<br>- 2024-05-08: Made public, updated the first paragraph (including changing manuscript status to accepted), and added contact information for further inquiries.<br>- 2024-06-20: Added DOI link to published manuscript in JGR:ES. Added a reference to our ESPL paper for those interested in more methodology details. Expanded the description of how the data were collected and processed, as well as my contact information, to make the repository a bit more user-friendly.</p>
A novel flow chamber for biodegradable alloy assessment in physiologically realistic environments: Supporting Data
<p>Experimental data including Excel analysis and microscopy supporting the publication 'A novel flow chamber for biodegradable alloy assessment in physiologically realistic environments' <a href="https://doi.org/10.1063/1.4821498" target="_blank" rel="noopener">https://doi.org/10.1063/1.4821498</a></p>
A corrosion model for bioabsorbable metallic stents: Supporting Data
<p>Data including UMATs, Abaqus input files and experimental measurements related to the paper 'A corrosion model for bioabsorbable metallic stents' <a title="Persistent link using digital object identifier" href="https://doi.org/10.1016/j.actbio.2011.05.032" target="_blank" rel="noreferrer noopener"><span>https://doi.org/10.1016/j.actbio.2011.05.032</span></a></p> <p> </p> <p> </p>
A physical corrosion model for bioabsorbable metal stents: Supporting Data
<p>Data including UMATs and Abaqus input files related to the paper 'A physical corrosion model for bioabsorbable metal stents' <a title="Persistent link using digital object identifier" href="https://doi.org/10.1016/j.actbio.2013.12.059" target="_blank" rel="noreferrer noopener"><span>https://doi.org/10.1016/j.actbio.2013.12.059</span></a></p>
Comparing coronary stent material performance on a common geometric platform through simulated bench testing: Supporting data
<p>Data including UMATs and Abaqus input files related to the paper 'Comparing coronary stent material performance on a common geometric platform through simulated bench testing' <a title="Persistent link using digital object identifier" href="https://doi.org/10.1016/j.jmbbm.2012.02.013" target="_blank" rel="noreferrer noopener"><span>https://doi.org/10.1016/j.jmbbm.2012.02.013</span></a></p>
Optimizing the design of a bioabsorbable metal stent using computer simulation methods: Supporting Data
<p>Data including UMATs and Abaqus input files related to the paper 'Optimizing the design of a bioabsorbable metal stent using computer simulation methods' <a title="Persistent link using digital object identifier" href="https://doi.org/10.1016/j.biomaterials.2013.07.010" target="_blank" rel="noreferrer noopener"><span>https://doi.org/10.1016/j.biomaterials.2013.07.010</span></a></p> <p> </p>
The Mechanical Performance of Permanent and Bioabsorbable Metal Stents: Supporting Data
<p>Materials including scripts, finite element models and experimental data that were created during the Phd work toward 'The Mechanical Performance of Permanent and Bioabsorbable Metal Stents' http://hdl.handle.net/10379/3744 but wasn't ultimately used in the thesis or publications.</p>
Computational micromechanics of bioabsorbable magnesium stents: Supporting Data
<p>Data including UMATs, Abaqus input files and experimental measurements related to the paper 'Computational micromechanics of bioabsorbable magnesium stents' <a title="Persistent link using digital object identifier" href="https://doi.org/10.1016/j.jmbbm.2014.01.007" target="_blank" rel="noreferrer noopener"><span>https://doi.org/10.1016/j.jmbbm.2014.01.007</span></a></p>
Influence of statistical size effects on the plastic deformation of coronary stents: Supporting data
<p>Data including UMATs and Abaqus input files related to the paper 'Influence of statistical size effects on the plastic deformation of coronary stents' <a title="Persistent link using digital object identifier" href="https://doi.org/10.1016/j.jmbbm.2012.12.008" target="_blank" rel="noreferrer noopener"><span>https://doi.org/10.1016/j.jmbbm.2012.12.008</span></a></p>
Supporting material for: MoonIndex, an Open-Source Tool to Generate Spectral Indexes for the Moon from M3 Data
<p>Supplementary material for the paper called: MoonIndex, an Open-Source Tool to Generate Spectral Indexes for the Moon from M3 Data. The data without "indexes" in the name are map-projected M3 cubes, they can be used in the python library <i><strong>MoonIndex </strong></i>to obtain the spectral indexes stored in the files with "indexes" in the name.</p><p>This research was done on the framework of the EXPLORE project, that has received funding from the European Union's 2020 research and innovation program under grant agreement No 101004214. </p>
Supporting Information for: Single-fly genome assemblies fill major phylogenomic gaps across the Drosophilidae Tree of Life
<p>This data repository contains supporting information, data, and code for figures and analysis pipelines the PLOS Biology article: "Single-fly genome assemblies fill major phylogenomic gaps across the Drosophilidae Tree of Life."</p> <ul> <li><strong>4d_full.treefile</strong>: Data underlying Figure 1 (note: tree was plotted as a cladogram and key groups collapsed on iToL; the treefile was not modified) and Figure S1.</li> <li><strong>S2_data.csv</strong>: Data underlying Figure 2.</li> <li><strong>S3_data.csv</strong>: Data underlying Figure 3.</li> <li>Data underlying Figure 4 is found in Table S4 of supplementary_tables.xlsx in the main manuscript</li> <li><strong>S5_data.csv</strong> Data underlying Figure 5</li> <li><strong>S6_data.csv</strong> Data underlying Figure S2 </li> <li><strong>illumina_only_assms.tar.gz</strong>: Archive of Illumina-only assemblies (FASTA) based on publicy available data that we did not generate. Assemblies generated from our own short-read data have been submitted to NCBI GenBank.</li> <li><strong>illumina_vcfs.tar.gz</strong>: Illumina-based variant calls and BED tracks of masked bases.</li> <li><strong>genomes.tar.gz</strong>: Genome files, for archival purposes.</li> <li><strong>repeatModeler-lib.tar.gz</strong>: RepeatModeler2 libraries.</li> <li><strong>diploid_genomes.tar.gz</strong>: diploid genomes and BED tracks of phased regions.</li> <li><strong>trees.tar.gz</strong>: phylogenies</li> </ul>
Рис. 6. Ювенильные раковины Laternula elliptica: А1, А3 – левые створки, внешний вид, H×L=3.0×4.4 мм; А2 – вид со стороны дорсального краЯ на сдвоенные створки, обраЗуюЩие по Заднему краю ЗиЯние; А4 – Замок, соединЯюЩий фрагменты раЗрушенных створок (штриховка); Б1 – праваЯ створка, внешний вид, H×L=8.5×14.0 мм; Б2 – внутреннЯЯ поверхность правой створки. Фрагменты раковины вЗрослого моллюска (L=69.7 мм): В1 – вид со стороны дорсального краЯ; В2 – фрагмент правой створки, вид сбоку. ОбоЗначениЯ: ЗК – Задний край; дК – дорсальный край; сКп – складки периостракума; м – макушка; мщ – макушечнаЯ Щель; пр – продиссоконх; хр – хондрофор; ппЛ – поддерживаюЩаЯ пластинка; дпЛ – дополнительнаЯ пластинка; син – синус. Fig. 6. Juvenile shells of Laternula elliptica: A1, A3 – left valves, external view, H×L=3.0×4.4 mm; A2 – paired valves, dorsal view, showing gape through which the siphon project; A4 – hinge with chondrophore and buttress, internal view; Б1– right valve, external view, H×L=8.5×14.0 mm; Б2 – right valve, internal view. Adult shell (L=69.7 мм): B1 – fragment of right valve, dorsal view; B2 – fragment of right valve, lateral view on umbo. Notes: ЗК – posterior margin; дК – dorsal margin; сКп – periostracal wrinkles; м – umbo; мщ – umbonal crack; пр – prodissoconch; хр – chondrophore; ппЛ – buttress; дпЛ – additional supporting plate; син – sinus. in Species of warm-water origin Laternula elliptica (King, 1832) (Mollusca: Bivalvia: Laternulidae), a widespread mollusk in recent Antarctica
Рис. 6. Ювенильные раковины Laternula elliptica: А1, А3 – левые створки, внешний вид, H×L=3.0×4.4 мм; А2 – вид со стороны дорсального краЯ на сдвоенные створки, обраЗуюЩие по Заднему краю ЗиЯние; А4 – Замок, соединЯюЩий фрагменты раЗрушенных створок (штриховка); Б1 – праваЯ створка, внешний вид, H×L=8.5×14.0 мм; Б2 – внутреннЯЯ поверхность правой створки. Фрагменты раковины вЗрослого моллюска (L=69.7 мм): В1 – вид со стороны дорсального краЯ; В2 – фрагмент правой створки, вид сбоку. ОбоЗначениЯ: ЗК – Задний край; дК – дорсальный край; сКп – складки периостракума; м – макушка; мщ – макушечнаЯ Щель; пр – продиссоконх; хр – хондрофор; ппЛ – поддерживаюЩаЯ пластинка; дпЛ – дополнительнаЯ пластинка; син – синус. Fig. 6. Juvenile shells of Laternula elliptica: A1, A3 – left valves, external view, H×L=3.0×4.4 mm; A2 – paired valves, dorsal view, showing gape through which the siphon project; A4 – hinge with chondrophore and buttress, internal view; Б1– right valve, external view, H×L=8.5×14.0 mm; Б2 – right valve, internal view. Adult shell (L=69.7 мм): B1 – fragment of right valve, dorsal view; B2 – fragment of right valve, lateral view on umbo. Notes: ЗК – posterior margin; дК – dorsal margin; сКп – periostracal wrinkles; м – umbo; мщ – umbonal crack; пр – prodissoconch; хр – chondrophore; ппЛ – buttress; дпЛ – additional supporting plate; син – sinus.
Supporting data for "Percolation transition and bimodal density distribution in hdyrogen fluoride", J. Chem. Phys. 160, 204503 (2024)
<p>GROMACS input files for the simulation of hydrogen fluoride using the polarizable model of Pártay, Jedlovszky and Vallauri [<em>J. Chem. Phys. </em>124, 184504 (2006)] adapted for the Drude oscillator model, as published in <em>J. Chem. Phys.</em> 160, 204503 (2024) <a href="https://doi.org/10.1063/5.0207202" target="_blank" rel="noopener">https://doi.org/10.1063/5.0207202</a></p>
Supporting data for: Angiosperms in a conservation area in the semiarid region of Paraíba State, Northeastern Brazil
<h3>Title: Angiosperms in a conservation area in the semiarid region of Paraíba State, Northeastern Brazil.</h3> <p>Contact information: Bernardo de Farias Rocha, bernardorocha284@gmail.com, and José Iranildo Miranda de Melo, tournefort@gmail.com, Universidade Estadual da Paraíba.</p> <p>Figures and table produced to illustrate an article, disponibilized as supporting data.</p> <p>Geographical Coordinates of the Study Area: 6º27'S, 36º18'W</p>
The Provincelands of Cape Cod National Seashore, Barnstable County, Massachusetts, USA. The reddish vegetation in the center of the photo is a cranberry (Vaccinium macrocarpon) bog, a wetland used for breeding by the Fowler's toad. The surrounding landscape is ideal for the Fowler's toad and supports one of the largest populations of this species in the United States. The landscape contains a patchwork of sand, pitch pine (Pinus rigida), scrub oak (Quercus ilicifolia), and dune grass (Ammophila breviligulata). Photo by Rebecca Flaherty. in Fowler's Toad (Anaxyrus fowleri) occupancy in the southern mid-Atlantic, USA
The Provincelands of Cape Cod National Seashore, Barnstable County, Massachusetts, USA. The reddish vegetation in the center of the photo is a cranberry (Vaccinium macrocarpon) bog, a wetland used for breeding by the Fowler's toad. The surrounding landscape is ideal for the Fowler's toad and supports one of the largest populations of this species in the United States. The landscape contains a patchwork of sand, pitch pine (Pinus rigida), scrub oak (Quercus ilicifolia), and dune grass (Ammophila breviligulata). Photo by Rebecca Flaherty.
Rock magnetic data from IODP Exp. 382 Sites U1537 and U1538 to support Reilly et al. "A geochemical mechanism for >10 m offsets of magnetic reversals inferred from the comparison of two Scotia Sea drill sites"
<p>Rock magnetic data from IODP Exp. 382 Sites U1537 and U1538 to support Reilly et al. "A geochemical mechanism for >10 m offsets of magnetic reversals inferred from the comparison of two Scotia Sea drill sites"</p><p>Excel Files:</p><ul><li>U1537_CubeSummary_Zenodo.xlsx : Summary of NRM, ARM, IRM, and magnetic susceptibility investigations on U1537 cube samples</li><li>U1538_CubeSummary_Zenodo.xlsx : Summary of NRM, ARM, IRM, and magnetic susceptibility investigations on U1538 cube samples</li></ul><p>Zip Files:</p><ul><li>FORC_Data.zip : First order reversal curve data files in MicroMag format for samples discussed in paper</li><li>DCD_Data.zip : DC Demagnetization curve data files for samples discussed in paper</li><li>Hysteresis_Data.zip : Hysteresis Loops for samples discussed in paper</li><li>MPMS_Data.zip : Data collected on Magnetics Property Measurement System 3, including Field Cooled/Zero Field Cooled Curves, Low Temperature Cycling of Room Temperature IRM, and AC Susceptibility</li></ul><p> </p><p>NRM = Natural Remanent Magnetization; ARM = Anhysteretic Remanent Magnetization; IRM = Isothermal Remanent Magnetization</p>
Dense vegetation hinders sediment transport towards saltmarsh interiors - Supporting data and source code (Part III: Extra runs)
<p>This is Part III of the supporting data and source code for the paper entitled "Dense vegetation hinders sediment transport towards saltmarsh interiors", submitted to <em>Limnology and Oceanography Letters.</em> It contains all input and output files for the extra simulations used in the paper (Figures S3, S8-S10).</p> <p>Each zip file corresponds to a model run. </p> <p>TIGER_XX.zip: Scenario XX, hydro-morphodynamics and vegetation dynamics, years 0-100.<br>TIGER_XX_100.zip: Scenario XX, hydro-morphodynamics and vegetation dynamics, years 100-200.<br>TIGER_XX_HYYY.zip: Scenario XX, hydro-morphodynamics only, year YYY.</p> <p>Main scenarios:<br>- 01: Spartina (Figures 1-5, S3-S10)<br>- 02: Salicornia (Figures 1-5, S3-S10)<br>- 83: No vegetation (Figures 1-5, S3, S8-S10)</p> <p>Additional scenarios:<br>- 146: Spartina, low bulk drag coefficient (Figure S3)<br>- 147: Spartina, very low bulk drag coefficient (Figure S3)<br>- 148: Salicornia, low bulk drag coefficient (Figure S3)<br>- 149: Salicornia, very low bulk drag coefficient (Figure S3)<br>- 122: Spartina, low settling velocity (Figure S8)<br>- 123: Spartina, high settling velocity (Figure S8)<br>- 124: Salicornia, low settling velocity (Figure S8)<br>- 125: Salicornia, high settling velocity (Figure S8)<br>- 126: No vegetation, low settling velocity (Figure S8)<br>- 127: No vegetation, high settling velocity (Figure S8)<br>- 128: Spartina, low critical bed erosion shear stress (Figure S8)<br>- 129: Spartina, high critical bed erosion shear stress (Figure S8)<br>- 130: Salicornia, low critical bed erosion shear stress (Figure S8)<br>- 131: Salicornia, high critical bed erosion shear stress (Figure S8)<br>- 132: No vegetation, low critical bed erosion shear stress (Figure S8)<br>- 133: No vegetation, high critical bed erosion shear stress (Figure S8)<br>- 134: Spartina, low Partheniades constant (Figure S8)<br>- 143: Spartina, high Partheniades constant (Figure S8)<br>- 136: Salicornia, low Partheniades constant (Figure S8)<br>- 144: Salicornia, high Partheniades constant (Figure S8)<br>- 138: No vegetation, low Partheniades constant (Figure S8)<br>- 145: No vegetation, high Partheniades constant (Figure S8)<br>- 150: Spartina, low sediment dry bulk density (Figure S8)<br>- 151: Spartina, high sediment dry bulk density (Figure S8)<br>- 152: Salicornia, low sediment dry bulk density (Figure S8)<br>- 153: Salicornia, high sediment dry bulk density (Figure S8)<br>- 154: No vegetation, low sediment dry bulk density (Figure S8)<br>- 155: No vegetation, high sediment dry bulk density (Figure S8)<br>- 76: Spartina, replicate #1 (Figures S9-S10)<br>- 77: Spartina, replicate #2 (Figures S9-S10)<br>- 78: Spartina, replicate #3 (Figures S9-S10)<br>- 88: Spartina, replicate #4 (Figures S9-S10)<br>- 80: Salicornia, replicate #1 (Figures S9-S10)<br>- 81: Salicornia, replicate #2 (Figures S9-S10)<br>- 82: Salicornia, replicate #3 (Figures S9-S10)<br>- 89: Salicornia, replicate #4 (Figures S9-S10)<br>- 85: No vegetation, replicate #1 (Figures S9-S10)<br>- 86: No vegetation, replicate #2 (Figures S9-S10)<br>- 87: No vegetation, replicate #3 (Figures S9-S10)<br>- 90: No vegetation, replicate #4 (Figures S9-S10)</p> <p> </p>
Dense vegetation hinders sediment transport towards saltmarsh interiors - Supporting data and source code (Part V: Figures)
<p>This is Part V of the supporting data and source code for the paper entitled "Dense vegetation hinders sediment transport towards saltmarsh interiors", submitted to <em>Limnology and Oceanography Letters.</em> It contains all input and output files to generate the figures of the paper.</p> <p>To be able to run the scripts as is, the path (at the beginning of each script) to the following folders must be updated:</p> <p>Runs (includes all model run folders from Part II and Part III)<br>Post (includes all post-processing folders from Part IV)</p>
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.