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641
datasets available to search
ShareScore release 0.9.0
Dataset results
641 results for “Protein interaction”
The RNA-binding proteins Roquin-1 and Regnase-1 interact and cooperate to prevent autoimmunity
GEO Series GSE152961. Mus musculus. 64 samples. Type: Expression profiling by high throughput sequencing.
An RNA-interacting protein network regulates pluripotency in mammalian primordial germ cells (Dazl testis RNA-IP)
GEO Series GSE39545. Mus musculus. 8 samples. Type: Expression profiling by array.
Characterization of the interaction between SARS-CoV-2 Membrane Protein and Proliferating Cell Nuclear Antigen (PCNA) as a Potential Therapeutic Target
<p>In this dataset, we have validated and explored the interaction between the SARS-CoV-2 M protein and the cellular protein PCNA, an interaction that was previously described by another proteomics study (Gordon et al., 2020). PCNA is an important nuclear protein involved in DNA replication and repair in the cell. The M-protein-PCNA interaction characterized here impacted the cell physiology, including increased localization of PCNA in the cytoplasm and associated DNA damage markers. These phenomena may have consequences for the fate of cells infected with SARS-CoV-2 and for the outcomes of COVID-19, such as persistent DNA damage after the infection. Finally, we show that inhibitors of PCNA and cell nuclear transport present effects in SARS-CoV-2 replication in vitro. Similar results have been presented by other RNA viruses in the literature. In sum, this study sheds light on novel molecular mechanisms of SARS-CoV-2 replication.</p>
Single-molecule fingerprinting of protein-drug interaction using a funneled biological nanopore
<p>This dataset belongs to “Single-molecule fingerprinting of protein-drug interaction using a funneled biological nanopore” and describes the raw micrograph dataset from negative-stain electron microscopy for YaxAB-C8, -C9, -C10.</p>
HCP5 inhibits apoptosis via c-Myc transcriptional regulation mediated by UTP3 based chromatin-RNA-binding protein interaction [ATAC-Seq]
GEO Series GSE200373. Homo sapiens. 12 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Single-molecule analysis of RNA:protein interactions reveals sequential binding of different YTHDF proteins to the same mRNA molecules [RIP-Seq]
GEO Series GSE201540. Homo sapiens. 36 samples. Type: Expression profiling by high throughput sequencing; Other.
The human AlkB homologue 4 interacts with proteins associated with transcription (methylation)
GEO Series GSE39126. Homo sapiens. 12 samples. Type: Methylation profiling by array.
An in situ method for identification of transcriptome-wide protein-RNA interactions in cells [eCLIP-seq ]
GEO Series GSE240521. Mus musculus. 2 samples. Type: Expression profiling by high throughput sequencing.
MTA1 interacts with primary RNAs to regulate expression and AS by protein dependent manner
GEO Series GSE102636. Homo sapiens. 14 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.
A complete map of affinity and specificity encoding for a partially fuzzy protein interaction
GEO Series GSE265816. Saccharomyces cerevisiae. 32 samples. Type: Other.
Puerarin attenuates diabetic kidney injury through interaction with Guanidine nucleotide-binding protein Gi subunit alpha-1 (Gnai1) subunit
GEO Series GSE196780. Mus musculus. 11 samples. Type: Expression profiling by high throughput sequencing.
Hsa_circ_0005358 suppresses cervical cancer metastasis via interacting with PTBP1 protein to destabilize CDCP1 mRNA [si-oligo vs si-PTBP1]
GEO Series GSE168907. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
The zinc finger protein CLAMP promotes long-range chromatin interactions that mediate dosage compensation of the Drosophila male X-chromosome
GEO Series GSE130546. Drosophila melanogaster. 36 samples. Type: Other.
Tracking live-cell single-molecule dynamics enables measurements of heterochromatin-associated protein-protein interactions
GEO Series GSE263472. Schizosaccharomyces pombe. 5 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
YAP1 fusion proteins drive forebrain ependymoma tumorigenesis via the interaction with TEAD transcription factors
GEO Series GSE110625. Mus musculus. 10 samples. Type: Expression profiling by array.
Benchmark of chromatin-protein interaction methods in haploid round spermatids
GEO Series GSE286751. Mus musculus. 14 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
ExoChew-Seq: An in vitro method for investigating singlestranded DNA-protein interactions
GEO Series GSE308562. Escherichia coli; Mus musculus. 2 samples. Type: Other.
RNA-Binding Protein Trx regulates alternative splicing and promotes metastasis of HCC via interacting with LINC00152
GEO Series GSE245587. Homo sapiens. 6 samples. Type: Expression profiling by array.
A MIR17HG-derived Long Noncoding RNA Provides an Essential Chromatin Scaffold for Protein Interaction and Myeloma Growth
GEO Series GSE208599. Homo sapiens. 12 samples. Type: Expression profiling by high throughput sequencing; Expression profiling by array.
The human AlkB homologue 4 interacts with proteins associated with transcription
GEO Series GSE39135. Homo sapiens. 24 samples. Type: Expression profiling by array; Methylation profiling by array.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.