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1,624 results for “Steroids”
Fig. 4 in Secoergostane- and ergostane-type steroids from Pleurotus cornucopiae var. citrinopileatus
Fig. 4. NOESY correlations and pyridine-induced deshielding effects observed for compound 3.
Clinical benefits of sex steroids given as a priming prior to GH provocative test or as a growth-promoting therapy in peripubertal growth delays: Results of a retrospective study among ENDO-ERN centres
<p>Objectives: Sex steroids, administered as a priming before GH stimulation tests<br> (GHST) to differentiate between growth hormone deficiency (GHD) and constitutional<br> delay of growth and puberty (CDGP) or as growth-promoting therapy using<br> low-dose sex steroids (LDSS) in CDGP, are much debated. We aimed to compare auxological<br> outcomes of CDGP or GHD children undergoing primed or unprimed GHST<br> and to evaluate LDSS treatment in CDGP.<br> Design: Retrospective study among three paediatric University Hospitals in Italy and<br> UK.<br> Methods: 184 children (72 females) aged 12.4 ± 2.08 years underwent primed (/P+)<br> or unprimed (/P−) GHST and were followed up until final height (FH). CDGP patients<br> were untreated (CDG P−) or received LDSS (CDGP+). The cohort included 34 CDG<br> P−/P+, 12 CDGP+/P+, 51 GHD/P+, 29 CDG P−/P−, 2 CDGP+/P− and 56 GHD/P−. FH<br> standard deviation score (SDS), Δ SDS FH-target height (TH) and degree of success<br> (−1 ≤ Δ SDS FH-SDS TH ≤ +1) were outcomes of interest.<br> Results: GHD/P+ had better FH-SDS (−0.87 vs −1.49; P = .023) and ΔSDS FH-TH<br> (−0.35 vs −0.77; P = .002) than CDGP−/P+. Overall, GHD/P+ showed the highest degree<br> of success (90%, P = .006). Regardless of priming, both rhGH and LDSS improved<br> degree of success compared to no treatment (89% and 86% vs 63%, P = .0009).<br> GHD/P+ showed a trend towards a higher proportion of permanent GHD compared<br> to GHD/P- (30.43% vs 15.09%; P = .067).<br> Conclusion: In peripubertal children, priming before GHST improves diagnostic accuracy<br> of GHST for idiopathic GHD. LDSS treatment improves auxological outcomes<br> in CDGP</p>
Different plasma steroid profiles between patients with and without diabetes mellitus in non-functioning adrenal incidentalomas
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Figure 3 in Differential gene expression pattern and plasma sex steroids during testicular development in Genyatremus luteus (Perciforme: Haemulidae) (Bloch, 1790)
Figure 3. Gene expression of er (A) andlhr (B) in the male gonad of Genyatremus luteus individuals at different maturation stages. Columns represent arithmetic mean and standard error of the mean. abc Different letters indicate statistically significant difference (p<0.05).
Figure 2 in Intragonadal evaluation of sexual steroid hormones during three reproductive events in two species of Peromyscus (Rodentia: Cricetidae)
Figure 2. Production and biotransformation profiles in four selected SSH of the ∆4 pathway by reproductive event in two species of Peromyscus. Mean intraovarian concentrations of sexual steroid hormones ([SSH]: progesterone, P4; androstenedione, A, testosterone, T; estradiol, E2) were assessed in free-living, adult females of P. melanotis (A) and P. difficilis (B), during estrous cycle (PRO, proestrus; EST, estrus; MET, metestrus; DIE, diestrus), pregnancy (early gestation, G1; late gestation, G2), and overall lactation. Bars depict mean [SSH] and vertical whiskers the respective standard errors; arrows signal which [SSH] had significant differences with others; when more than one [SSH] was statistically different in ANOVA analyzes, horizontal lines were added and arrows below and above them signal the respective [SSH]; number of asterisks indicate degree of significance in p-values (see Methods, Results, and the ANOVA in Table S1): * = significant; ** = very significant; *** = extremely significant; the plus sign (+) shows an almost statistically significant instance. Note that scales of plots differ.
Figure 4 in Intragonadal evaluation of sexual steroid hormones during three reproductive events in two species of Peromyscus (Rodentia: Cricetidae)
Figure 4. Comparison of intraovarian contents of each steroid hormone in two Peromyscus species: (A) progesterone [P4], (B) Androstenedione [A], (C) Testosterone [T1], (D) Estradiol [E2]. Concentrations curves include a complete estrous cycle (CEC) and a successful estrous cycle (SEC; i.e., followed by pregnancy and lactation), in free-living, adult females of P. melanotis (open markers) and P. difficilis (closed markers). The arrow and asterisk signal the only interspecific significant difference. Symbology after Fig. 1.
PFAS and steroid hormones in human milk
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Archaeological Steroids Concentrations 2024.08.31
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Fig. 3. Selected 2D in Seladelicatulasine A-G, C steroidal glycosides with cholinesterase inhibitory activities from Selaginella delicatula
Fig. 3. Selected 2D NMR correlations of compound 6.
Fig. 2. Key HMBC and 1H–1H in Seladelicatulasine A-G, C steroidal glycosides with cholinesterase inhibitory activities from Selaginella delicatula
Fig. 2. Key HMBC and 1H–1H COSY correlations of compounds 1–5 and 7.
Fig. 1 in Seladelicatulasine A-G, C steroidal glycosides with cholinesterase inhibitory activities from Selaginella delicatula
Fig. 1. Structures of compounds 1–7 identified from S. delicatula.
Fig. 4 in Seladelicatulasine A-G, C steroidal glycosides with cholinesterase inhibitory activities from Selaginella delicatula
Fig. 4. Lineweavere-Burk plot for the inhibitin of AChE by compound 5.
Fig. 2. Key 2D NMR correlations for 1 in Steroid glycosides from the roots of Marsdenia tenacissima
Fig. 2. Key 2D NMR correlations for 1 and the ester fragments.
Fig. 1 in Steroid glycosides from the roots of Marsdenia tenacissima
Fig. 1. Chemical structures of 1–21 from M. tenacissima.
Fig. 5 in Steroid glycosides from the roots of Marsdenia tenacissima
Fig. 5. ECD and UV spectra of 4.
Fig. 3 in Steroid glycosides from the roots of Marsdenia tenacissima
Fig. 3. Plausible mechanism of the intramolecular transacetylation of 10/11 and 12/13.
Fig. 3 in 30-norlanostane triterpenoids and steroid derivatives from the endophytic fungus Aspergillus nidulans
Fig. 3. The key NOESY correlations of compounds 1–4.
Fig. 2. Key 1H–1H in 30-norlanostane triterpenoids and steroid derivatives from the endophytic fungus Aspergillus nidulans
Fig. 2. Key 1H–1H COSY and HMBC correlations of compounds 1–4.
Fig. 5 in 30-norlanostane triterpenoids and steroid derivatives from the endophytic fungus Aspergillus nidulans
Fig. 5. The experimental and calculated ECD spectra of compound 4.
Fig. 1 in 30-norlanostane triterpenoids and steroid derivatives from the endophytic fungus Aspergillus nidulans
Fig. 1. Chemical structures of compounds 1–10.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
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DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.