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619
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ShareScore release 0.9.0
Dataset results
619 results for “paternity”
A multi-omics census reveals miRNA miR-let-7 as instigator of paternal mitochondrial dysfunction and in epigenetic heredity of intergenerational metabolic decline [F1_Liv_eWAT_RNAseq]
GEO Series GSE282189. Mus musculus. 31 samples. Type: Expression profiling by high throughput sequencing.
Paternal exposure alone induces alcohol-related birth defects in a mouse model: Implications of paternal drinking in FAS birth defects.
GEO Series GSE218362. Mus musculus. 16 samples. Type: Expression profiling by high throughput sequencing.
Expression profile analysis of Drosophila melanogaster embryonic and larval MANF mutants together with paternal rescue and overexpression conditions
GEO Series GSE28820. Drosophila melanogaster. 24 samples. Type: Expression profiling by array.
Non-invasive prenatal paternity testing by analysis of Y-chromosome mini-STR haplotype using next-generation sequencing
GEO Series GSE186434. Homo sapiens. 14 samples. Type: Other.
The evolution of β-thalassemia major from minor is associated with paternal uniparental isodisomy of chromosome 11p15
GEO Series GSE7847. Homo sapiens. 10 samples. Type: Genome variation profiling by SNP array; SNP genotyping by SNP array.
Genome-wide Transcript Profiling of Endosperm without Paternal Contribution Identifies Parent-of-origin Dependent Regulation of AGAMOUS-LIKE 36
GEO Series GSE24809. Arabidopsis thaliana. 3 samples. Type: Expression profiling by array.
Paternal chronic folate supplementation induced transgenerational inheritance of acquired developmental and metabolic changes in chickens
GEO Series GSE122759. Gallus gallus. 34 samples. Type: Expression profiling by high throughput sequencing; Non-coding RNA profiling by high throughput sequencing.
Paternal nicotine enhances fear memory, reduces nicotine administration and alters hippocampal genetic and neural function in offspring [Bisulfite-seq]
GEO Series GSE140904. Mus musculus. 24 samples. Type: Methylation profiling by high throughput sequencing.
Alteration in mRNA expression in hippocampus and next-generation effects due to paternal exposure to the neonicotinoid pesticide clothianidin
GEO Series GSE281282. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
Low paternal dietary folate alters the sperm epigenome and is associated with negative pregnancy outcomes
GEO Series GSE52017. Mus musculus. 2 samples. Type: Genome binding/occupancy profiling by genome tiling array.
Paternal overdiet drives intergenerational transmission of metabolic disorders through sperm epigenetic alteration [MeDIP-Seq]
GEO Series GSE132612. Mus musculus. 4 samples. Type: Methylation profiling by high throughput sequencing.
Paternal imprinting of dosage-effect defective1 contributes to seed weight xenia in maize
GEO Series GSE183304. Zea mays. 9 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.
A multi-omics census reveals miRNA miR-let-7 as instigator of paternal mitochondrial dysfunction and in epigenetic heredity of intergenerational metabolic decline
GEO Series GSE280278. Mus musculus. 279 samples. Type: Expression profiling by high throughput sequencing; Non-coding RNA profiling by high throughput sequencing.
Paternal nicotine exposure promotes hepatic fibrosis in offspring
GEO Series GSE155308. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
Autism-linked UBE3A gain-of-function mutation causes interneuron and behavioral phenotypes when inherited maternally or paternally in mice
<p>The E3 ubiquitin ligase Ube3a is biallelically expressed in mitotic cells, including neural progenitors and glial cells, raising the possibility that UBE3A gain-of-function mutations might cause neurodevelopmental disorders irrespective of parent-of-origin. To test this possibility, we engineered a mouse line that harbors an autism-linked UBE3A-T485A (T508A in mouse) gain-of-function mutation and evaluated phenotypes in animals that inherited the mutant allele paternally, maternally, or from both parents. We found that both paternally and maternally expressed UBE3A-T485A resulted in elevated UBE3A activity in neural progenitors and glial cells where Ube3a is biallelically expressed. Expression of UBE3A-T485A from the maternal allele, but not the paternal one, led to a persistent elevation of UBE3A activity in postmitotic neurons. Maternal, paternal, or biparental inheritance of the mutant allele promoted embryonic expansion of Zcchc12 lineage interneurons which mature into Sst and Calb2 expressing interneurons, and caused a spectrum of behavioral phenotypes that differed by parent-of-origin. Phenotypes were distinct from those observed in Angelman syndrome model mice that harbor a Ube3a maternal loss-of-function allele. Our study shows that the UBE3A-T485A gain-of-function mutation causes distinct neurodevelopmental phenotypes when inherited maternally or paternally. These findings have clinical implications for a growing number of disease-linked UBE3A gain-of-function mutations.</p> <p>Single-cell RNA-seq (drop-seq) of mouse cerebral cortex from Ube3a-WT, Ube3a-T485A homozygotes, assessed at two ages: E14.5 and P0</p>
Paternal high-fat diet elicits early-onset se-specific islet inflammation in rat progeny
GEO Series GSE89138. Rattus norvegicus. 20 samples. Type: Expression profiling by array.
Paternal high-fat diet affects weight and DNA methylation of their offspring
GEO Series GSE261084. Rattus norvegicus. 10 samples. Type: Methylation profiling by high throughput sequencing.
Paternal nicotine enhances fear memory, reduces nicotine administration and alters hippocampal genetic and neural function in offspring
GEO Series GSE140905. Mus musculus. 48 samples. Type: Expression profiling by high throughput sequencing; Methylation profiling by high throughput sequencing.
Comparison of the effects of paternal obesity upon gene expression in mice
GEO Series GSE218120. Mus musculus. 16 samples. Type: Expression profiling by array.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.