Find research datasets worth reusing
Search datasets from major research repositories and use ShareScore to quickly assess how well each record supports discovery, access, and reuse.
6,234
datasets available to search
ShareScore release 0.9.0
Dataset results
6,234 results for “phenotypes”
Abdominal obesity phenotype is associated with COVID-19 chest X-ray severity score better than BMI-based obesity
<p>Malavazos AE, Secchi F, Basilico S, Capitanio G, Boveri S, Milani V, Dubini C, Schiaffino S, Morricone L, Foschini C, Gobbo G, Piccinni R, Saibene A, Sardanelli F, Menicanti L, Guazzi M, Dong C, Romanelli MMC, Carruba M, Iacobellis G. Abdominal obesity phenotype is associated with COVID-19 chest X-ray severity score better than BMI-based obesity. Eat Weight Disord. 2022 Feb;27(1):345-359. doi: 10.1007/s40519-021-01173-w. Epub 2021 Apr 5. PMID: 33821453; PMCID: PMC8020829.</p> <p>Abstract</p> <p><strong>Purpose: </strong>Chest X-ray (CXR) severity score and BMI-based obesity are predictive risk factors for COVID-19 hospital admission. However, the relationship between abdominal obesity and CXR severity score has not yet been fully explored.</p> <p><strong>Methods: </strong>This retrospective cohort study analyzed the association of different adiposity indexes, including waist circumference and body mass index (BMI), with CXR severity score in 215 hospitalized patients with COVID-19.</p> <p><strong>Results: </strong>Patients with abdominal obesity showed significantly higher CXR severity scores and had higher rates of CXR severity scores ≥ 8 compared to those without abdominal obesity (P < 0.001; P = 0.001, respectively). By contrast, patients with normal weight, with overweight and those with BMI-based obesity showed no significant differences in either CXR severity scores or in the rates of CXR severity scores ≥ 8 (P = 0.104; P = 0.271, respectively). Waist circumference and waist-to-height ratio (WHtR) correlated more closely with CXR severity scores than BMI (r = 0.43, P < 0.001; r = 0.41, P < 0.001; r = 0.17, P = 0.012, respectively). The area under the curves (AUCs) for waist circumference and WHtR were significantly higher than that for BMI in identifying a high CXR severity score (≥ 8) (0.68 [0.60-0.75] and 0.67 [0.60-0.74] vs 0.58 [0.51-0.66], P = 0.001). A multivariate analysis indicated abdominal obesity (risk ratio: 1.75, 95% CI: 1.25-2.45, P < 0.001), bronchial asthma (risk ratio: 1.73, 95% CI: 1.07-2.81, P = 0.026) and oxygen saturation at admission (risk ratio: 0.96, 95% CI: 0.94-0.97, P < 0.001) as the only independent factors associated with high CXR severity scores.</p> <p><strong>Conclusion: </strong>Abdominal obesity phenotype is associated with a high CXR severity score better than BMI-based obesity in hospitalized patients with COVID-19. Therefore, when visiting the patient in a hospital setting, waist circumference should be measured, and patients with abdominal obesity should be monitored closely. Level of evidence Cross-sectional descriptive study, Level V.</p> <p> </p>
Cognitive, behavioral, and psychological phenotypes in small fiber neuropathy: a case-control study - Submitted
<p>Clinical dataset containing pseudoanonymized data on a cohort of small fiber neuropathy patients included in the study at title </p>
Phenotypical states modulate sensitivity and transcriptional reprogramming in patient-derived glioblastoma cells in response to temozolomide and radiation therapy. [RNA-Seq]
GEO Series GSE249544. Homo sapiens. 48 samples. Type: Expression profiling by high throughput sequencing.
Transcriptional and Phenotypic Reprogramming of Tumors by Host Stroma Deficient in TNFα Signaling
GEO Series GSE23002. Mus musculus. 8 samples. Type: Expression profiling by array.
CRISPR Phenotypic enrichment screen for epigenetic regulators of MEIS1 expression in acute myeloid leukemia (AML) [CRISPRScreens]
GEO Series GSE217778. Homo sapiens. 6 samples. Type: Other.
Induction of a colitogenic phenotype in Th1-like cells depends on interleukin-23 receptor signaling
GEO Series GSE164520. Mus musculus. 810 samples. Type: Expression profiling by high throughput sequencing.
Regulatory and epistatic networks unravel the complexity of piebald, a pigmentation phenotype in Merino sheep
GEO Series GSE24189. Ovis aries; Bos taurus. 20 samples. Type: Expression profiling by array.
Phenotypical states modulate sensitivity and transcriptional reprogramming in patient-derived glioblastoma cells in response to temozolomide and radiation therapy. [array]
GEO Series GSE249636. Homo sapiens. 36 samples. Type: Methylation profiling by array.
Identification of host regulators of Mycobacterium tuberculosis phenotypic states uncovers a role for the MMGT1-GPR156-lipid droplet axis in the induction of persistence
GEO Series GSE210691. Homo sapiens. 30 samples. Type: Expression profiling by high throughput sequencing; Other.
Systematic comparison of culture media uncovers phenotypic shift of primary human microglia defined by reduced reliance to CSF1R signaling
GEO Series GSE228755. Homo sapiens. 26 samples. Type: Expression profiling by high throughput sequencing.
Genetic analysis, ultrasound phenotype, and pregnancy outcome of fetuses with Xp22.33 or Yp11.32 microdeletion
GEO Series GSE223242. Homo sapiens. 5 samples. Type: Genome variation profiling by SNP array.
Genetic etiology and phenotypic characteristics of fetuses with 11q deletion (11q23.3-q25) syndrome
GEO Series GSE287321. Homo sapiens. 4 samples. Type: Genome variation profiling by SNP array.
VSMC phenotypic transition
GEO Series GSE229130. Mus musculus. 14 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.
Acquisition of CCDC88A/GIV through Tumor-Stroma Tunnels Promotes Aggressive Phenotypes of Estrogen Receptor-Positive Breast Cancer [dataset2]
GEO Series GSE224320. Homo sapiens. 21 samples. Type: Expression profiling by high throughput sequencing.
Medial prefrontal cortex: genes linked to bipolar disorder and schizophrenia have altered expression in the highly social maternal phenotype
GEO Series GSE54426. Mus musculus. 10 samples. Type: Expression profiling by array.
Regularity of Chondrocyte Phenotypic Changes Identified by Single-cell Sequencing in vitro
GEO Series GSE270642. Homo sapiens. 9 samples. Type: Expression profiling by high throughput sequencing.
A second genetic screen for gurken mRNA mislocalisation reveals novel phenotypes of the piRNA pathway mutants in Drosophila [RNA-seq]
GEO Series GSE293862. Drosophila melanogaster. 9 samples. Type: Expression profiling by high throughput sequencing.
Multi-omics and imaging mass cytometry characterization of human kidneys to identify pathways and phenotypes associated with kidney damage
GEO Series GSE217427. Homo sapiens. 44 samples. Type: Expression profiling by high throughput sequencing.
Efficacy of small molecule inhibitors and genetic interference of cGAS-STING axis on development of the senescence-associated secretory phenotype (SASP) in human stromal cells
GEO Series GSE128420. Homo sapiens. 18 samples. Type: Expression profiling by high throughput sequencing.
m6A independent genome-wide METTL3 and METTL14 redistribution drives senescence-associated secretory phenotype [carRNA-m6A-seq]
GEO Series GSE159550. Homo sapiens. 8 samples. Type: Other.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.