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6,234
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Dataset results
6,234 results for “phenotypes”
Comparative phenotypic and genome-wide expression analysis of ancestral Saccharomyces cerevisiae and a strain with higher flux through the pentose phosphate pathway
GEO Series GSE59504. Saccharomyces cerevisiae. 4 samples. Type: Expression profiling by array.
Characterization of novel ovarian tumor cell lines that retain the phenotype of primary tumors [MIP]
GEO Series GSE40786. Homo sapiens. 25 samples. Type: Genome variation profiling by SNP array; SNP genotyping by SNP array.
The metastatic microenvironment. Brain-derived soluble factors alter the malignancy phenotype of cutaneous and brain- metastasizing melanoma cells
GEO Series GSE34970. Homo sapiens. 4 samples. Type: Expression profiling by array.
Characterization of Streptococcus pneumoniae phage-like element SpnCI reveals an enhanced virulent phenotype in the acute invertebrate infection model Galleria mellonella
GEO Series GSE132556. Streptococcus pneumoniae. 6 samples. Type: Expression profiling by high throughput sequencing.
The zebrafish runzel mutant results in a novel muscular dystrophy phenotype due to a titin mutation
GEO Series GSE4585. Danio rerio. 6 samples. Type: Expression profiling by array.
JAK2V617F-dependent clonal hematopoiesis drives vascular resident macrophages toward a pathogenic phenotype and promotes dissecting aortic aneurysm
GEO Series GSE215455. Mus musculus. 10 samples. Type: Expression profiling by high throughput sequencing.
Transcriptomic Profiles of Multiple Organ Dysfunction Syndrome Phenotypes in Pediatric Critical Influenza
GEO Series GSE236877. Homo sapiens. 236 samples. Type: Expression profiling by array.
Loss of function mutation in progressive ankylosis (Ank) gene causes aberrant mineralization and acquisition of osteoblast-like-phenotype by annulus fibrosus cells in the intervertebral disc
GEO Series GSE206997. Mus musculus. 20 samples. Type: Expression profiling by array.
Effects of differences in donors and passage numbers of endothelial progenitor cell (EPC)-derived vascular endothelial cells (VECs) on the phenotype determination of VECs (type-I versus type-II).
GEO Series GSE61000. Homo sapiens. 3 samples. Type: Expression profiling by array.
Phenotypic cooperation of a KCNQ2 exon 7 partial duplication and compound copy number variations in genes associated to a severe epileptic and neurodevelopmental delay
GEO Series GSE122584. Homo sapiens. 4 samples. Type: Genome variation profiling by SNP array.
Phenotypic Plasticity upon GSC Differentiation
GEO Series GSE253400. Homo sapiens. 12 samples. Type: Expression profiling by array.
Mechanical confinement governs phenotypic plasticity in melanoma [ChIP-seq A375]
GEO Series GSE298796. Homo sapiens. 6 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Targeting of the YAP/SMAD molecular circuit inhibits a TGFb1-induced myofibroblast phenotype
GEO Series GSE108516. Homo sapiens. 5 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Phenotype and expression profile analysis of Staphylococcus aureus biofilms and planktonic cells in response to Licochalcone A
GEO Series GSE58938. Staphylococcus aureus. 8 samples. Type: Expression profiling by array.
Novel epilepsy phenotype associated to a known SCN8A mutation
<p>Raw data for the article</p> <p>Epifanio R, Zanotta N, Giorda R, Bardoni A, Zucca C. Novel epilepsy phenotype associated to a known SCN8A mutation. Seizure. 2019 Apr;67:15-17. doi: 10.1016/j.seizure.2019.01.017. Epub 2019 Mar 4. PMID: 30851583.</p>
Task 4.3 Table 4.3.1_Entries from high-protein vs conventional crosses utilized in N2-fixation phenotyping
<p>High-protein vs conventional crosses utilized in N2-fixation phenotyping listed in Table 4.3.1. </p>
Abdominal obesity phenotype is associated with COVID-19 chest X-ray severity score better than BMI-based obesity.
<p>Dataset from Malavazos AE, Secchi F, Basilico S, Capitanio G, Boveri S, Milani V, Dubini C, Schiaffino S, Morricone L, Foschini C, Gobbo G, Piccinni R, Saibene A, Sardanelli F, Menicanti L, Guazzi M, Dong C, Romanelli MMC, Carruba M, Iacobellis G. Abdominal obesity phenotype is associated with COVID-19 chest X-ray severity score better than BMI-based obesity. Eat Weight Disord. 2021 Apr 5:1–15. doi: 10.1007/s40519-021-01173-w. Epub ahead of print. PMID: 33821453; PMCID: PMC8020829.</p> <p>Abstract</p> <p><strong>Purpose: </strong>Chest X-ray (CXR) severity score and BMI-based obesity are predictive risk factors for COVID-19 hospital admission. However, the relationship between abdominal obesity and CXR severity score has not yet been fully explored.</p> <p><strong>Methods: </strong>This retrospective cohort study analyzed the association of different adiposity indexes, including waist circumference and body mass index (BMI), with CXR severity score in 215 hospitalized patients with COVID-19.</p> <p><strong>Results: </strong>Patients with abdominal obesity showed significantly higher CXR severity scores and had higher rates of CXR severity scores ≥ 8 compared to those without abdominal obesity (P < 0.001; P = 0.001, respectively). By contrast, patients with normal weight, with overweight and those with BMI-based obesity showed no significant differences in either CXR severity scores or in the rates of CXR severity scores ≥ 8 (P = 0.104; P = 0.271, respectively). Waist circumference and waist-to-height ratio (WHtR) correlated more closely with CXR severity scores than BMI (r = 0.43, P < 0.001; r = 0.41, P < 0.001; r = 0.17, P = 0.012, respectively). The area under the curves (AUCs) for waist circumference and WHtR were significantly higher than that for BMI in identifying a high CXR severity score (≥ 8) (0.68 [0.60-0.75] and 0.67 [0.60-0.74] vs 0.58 [0.51-0.66], P = 0.001). A multivariate analysis indicated abdominal obesity (risk ratio: 1.75, 95% CI: 1.25-2.45, P < 0.001), bronchial asthma (risk ratio: 1.73, 95% CI: 1.07-2.81, P = 0.026) and oxygen saturation at admission (risk ratio: 0.96, 95% CI: 0.94-0.97, P < 0.001) as the only independent factors associated with high CXR severity scores.</p> <p><strong>Conclusion: </strong>Abdominal obesity phenotype is associated with a high CXR severity score better than BMI-based obesity in hospitalized patients with COVID-19. Therefore, when visiting the patient in a hospital setting, waist circumference should be measured, and patients with abdominal obesity should be monitored closely. Level of evidence Cross-sectional descriptive study, Level V.</p>
PREVALENCE AND CLINICAL OUTCOME OF MAIN ECHOCARDIOGRAPHIC AND HEMODYNAMIC HEART FAILURE PHENOTYPES IN A POPULATION OF HOSPITALIZED PATIENTS 70 YEARS OLD AND OLDER
<p><strong>BACKGROUND</strong>: Heart failure (HF) echocardiographic and hemodynamic categories are poorly characterized in the elderly. We aimed to evaluate the prevalence and clinical outcomes of echocardiographic and hemodynamic HF phenotypes in a consecutive series of hospitalized patients aged ≥70 years.</p> <p><strong>METHODS: </strong>All consecutive patients ≥70 years old discharged from the Internal Medicine Unit of our Hospital with a diagnosis of HF, between January and November 2020, entered this retrospective study. All patients underwent physical examination, complete blood tests, chest-X ray and transthoracic echocardiography. At 1-year follow-up, we evaluated the occurrence of the composite outcome of all‐cause mortality and re-hospitalization.</p> <p><strong>RESULTS</strong>: 261 patients (86.3±6.4 yrs, 60.9% women) were retrospectively analyzed. From the study group, 106 “old” (70-84 yrs) and 155 “oldest-old” (≥85 yrs) patients were separately analyzed. A total of 169 (64.7%) patients reported the composite outcome during follow-up: 41 (15.7%) died and 128 (49.0%) were re-hospitalized. At 1-year follow-up, survival analysis did not show any statistically significant difference between age groups (p = 0.31) and between HF echocardiographic categories (p=0.34), whereas HF patients with “cold-dry” phenotype had significantly poorer survival compared to the other hemodynamic subtypes (p<0.001). Male sex (HR 1.44, 95%CI 1.04-1.98), “cold-dry” phenotype (HR 3.90, 95%CI 1.73-8.77), high sodium level (HR 1.03, 95%CI 1.01-1.04) and low estimated glomerular filtration rate (eGFR) (HR 0.98, 95%CI 0.97-0.99) were independently associated with the outcome occurrence.</p> <p><strong>CONCLUSIONS: </strong>Male sex, “cold-dry” phenotype, high sodium level and low eGFR are the main adverse prognostic indicators over a mid-term follow-up in hospitalized patients aged ≥70 yrs.</p>
Are behaviour and stress-related phenotypes in urban birds adaptive? : Data and scripts
<p>Data and scripts associated with the manuscript.</p>
Interacting effects of environmental enrichment across multiple generations on early life phenotypes in zebrafish (Danio rerio).
<p>CSV data files and R scripts required to replicate analysis of larval zebrafish morphometrics and locomotion data.</p>
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.