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2,009
datasets available to search
ShareScore release 0.9.0
Dataset results
2,009 results for “Disruption”
Aberrant splicing in Huntington’s disease accompanies disrupted TDP-43 activity and altered m6A RNA modifications [ISO-seq]
GEO Series GSE279460. Mus musculus. 16 samples. Type: Expression profiling by high throughput sequencing.
Copy number variations may contribute to congenital heart defect risk greatly by disrupting long noncoding RNAs
GEO Series GSE201076. Homo sapiens. 12 samples. Type: Expression profiling by high throughput sequencing.
Inducible disruption of Tet genes results in myeloid malignancy, readthrough transcription, and a heterochromatin-to-euchromatin switch [WGBS]
GEO Series GSE222725. Mus musculus. 8 samples. Type: Methylation profiling by high throughput sequencing.
Inhibition of casein kinase 2 disrupts differentiation of myeloid cells in cancer and enhances the efficacy of immunotherapy in mice
GEO Series GSE117712. Mus musculus. 10 samples. Type: Expression profiling by high throughput sequencing.
Disruption of Trim9 function abrogates macrophage motility in vivo
GEO Series GSE81317. Danio rerio. 52 samples. Type: Expression profiling by array.
Transcriptomic Characterization Reveals Disrupted Medium Spiny Neuron Trajectories in Huntington's Disease and Possible Therapeutic Avenues [bulk RNA-seq]
GEO Series GSE232646. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
Toxic C9orf72 poly(PR) binds heterochromatin, disrupts HP1α and causes dsRNA accumulation
GEO Series GSE124834. Mus musculus. 19 samples. Type: Expression profiling by high throughput sequencing.
Disruption of higher order nuclear condensates by a dominant negative FOXN1 mutation causes immunodeficiency
GEO Series GSE162668. Mus musculus; Homo sapiens. 36 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.
Recurrent disruption of HIP1 identified in patients with epilepsy, learning difficulties, intellectual disability, and neurobehavioral abnormalities
GEO Series GSE23834. Homo sapiens. 12 samples. Type: Genome variation profiling by genome tiling array.
Campylobacter concisus Impairs sodium absorption in colonic epithelium via ENaC dysfunction and claudin-8 disruption
GEO Series GSE141217. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
Disruption of developmental enhancer and PRC2 function by K27M in childhood glioma
GEO Series GSE154267. Homo sapiens; Mus musculus. 78 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.
Targeted disruption of Hotair leads to homeotic transformation and de-repression of imprinted genes [RNA-Seq, ChIP-Seq]
GEO Series GSE48005. Mus musculus. 12 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.
Neuronal DNA double-strand breaks lead to genome structural variations and 3D genome disruption in neurodegeneration [Mate-Pair]
GEO Series GSE227444. Mus musculus. 11 samples. Type: Other.
Targeted disruption of BCL11A-XL specific zinc finger motif for de-repression of fetal globin expression
GEO Series GSE229989. Homo sapiens. 8 samples. Type: Expression profiling by high throughput sequencing.
Disruption of dNTPs Homeostasis by Ribonucleotide Reductase Hyperactivation Overcomes AML Differentiation Blockade
GEO Series GSE193769. Homo sapiens. 8 samples. Type: Expression profiling by high throughput sequencing.
Disruption of FAT10-MAD2 binding inhibits tumor progression
GEO Series GSE54167. Homo sapiens. 10 samples. Type: Expression profiling by array.
Targeting Menin disrupts the KMT2A/B and polycomb balance to paradoxically activate bivalent genes
GEO Series GSE181829. Homo sapiens. 71 samples. Type: Expression profiling by high throughput sequencing; Other; Genome binding/occupancy profiling by high throughput sequencing.
Disruption of a GATA2, TAL1, ERG regulatory circuit promotes erythroid transition in healthy and leukemic stem cells
GEO Series GSE158797. Homo sapiens. 19 samples. Type: Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by high throughput sequencing.
Genetic disruption of the baculum compromises the ability of male mice to copulate [scRNA-seq]
GEO Series GSE290862. Mus musculus. 5 samples. Type: Expression profiling by high throughput sequencing.
Targeting Glioblastoma Stem Cells through Disruption of the Circadian Clock [ChIP-Seq]
GEO Series GSE134972. Homo sapiens. 12 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.