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1,351 results for “Intermediates”
Alphafold2_ab_initio iterative predictions for folding intermediate identification
<div>Iterative structure predictions for protein PDB ids starts from 4.</div>
Alphafold2_ab_initio iterative predictions for folding intermediate identification
<div>Iterative structure predictions for protein PDB ids starts from 3.</div> <div> <div> <p> </p> </div> </div>
Intermediate results of simulation study of the article "Modified Conditional Borrowing-by-part Power Prior for dynamic and parameter-specific information borrowing of the Gaussian endpoint".
<p>This file contains the intermediate results of the simulation study of the article "Modified Conditional Borrowing-by-part Power Prior for dynamic and parameter-specific information borrowing of the Gaussian endpoint".</p>
Data from: Two different strategies of host manipulation allow parasites to persist in intermediate-definitive host systems
Trophically-transmitted parasites start their development in an intermediate host, before they finish the development in their definitive host when the definitive host preys on the intermediate host. In intermediate-definitive host systems, two strategies of host manipulation have been evolved: increasing the rate of transmission to the definitive host by increasing the chance that the definitive host will prey on the intermediate host, or increasing the lifespan of the parasite in the intermediate host by decreasing the predation chance when the intermediate host is not yet infectious. As the second strategy is less well studied than the first, it is unknown under what conditions each of these strategies are prevailed and evolved. We analysed the effect of both strategies on the presence of parasites in intermediate-definitive host systems with a structured population model. We show that the parasite can increase the parameter space where it can persist in the intermediate-definitive host system by using one of these two strategies of host manipulation. We found that when the intermediate host or the definitive host have life-history traits that allow the definitive host to reach large population densities, i.e. high reproduction rate of the intermediate host or high conversion efficiency of the definitive host (efficiency at which the uninfected definitive host converts caught intermediate hosts into offspring) respectively, evolving manipulation to decrease the predation chance of the intermediate host will be more beneficial than manipulation to increase the predation chance to enhance transmission. Furthermore, manipulation to decrease the predation chance of the intermediate host results in higher population densities of infected intermediate hosts than manipulation that increases the predation chance to enhance transmission. Our study shows that host manipulation in early stages of the parasite development to decrease predation might be a more frequently evolved way of host manipulation than is currently assumed.
Data from: Reproductive workers show queen-like gene expression in an intermediately eusocial insect, the buff-tailed bumble bee Bombus terrestris
Bumble bees represent a taxon with an intermediate level of eusociality within Hymenoptera. The clear division of reproduction between a single founding queen and the largely sterile workers is characteristic for highly eusocial species, whereas the morphological similarity between the bumble bee queen and the workers is typical for more primitively eusocial hymenopterans. Also, unlike other highly eusocial hymenopterans, division of labour among worker subcastes is plastic and not predetermined by morphology or age. We conducted a differential expression analysis based on RNA-seq data from 11 combinations of developmental stage and caste to investigate how a single genome can produce the distinct castes of queens, workers and males in the buff-tailed bumble bee Bombus terrestris. Based on expression patterns, we found males to be the most distinct of all adult castes (2411 transcripts differentially expressed compared to nonreproductive workers). However, only relatively few transcripts were differentially expressed between males and workers during development (larvae: 71 and pupae: 162). This indicates the need for more distinct expression patterns to control behaviour and physiology in adults compared to those required to create different morphologies. Among female castes, reproductive workers and their nonreproductive sisters displayed differential expression in over ten times more transcripts compared to the differential expression found between reproductive workers and their mother queen. This suggests a strong shift towards a more queenlike behaviour and physiology when a worker becomes fertile. This contrasts with eusocial species where reproductive workers are more similar to nonreproductive workers than the queen.
Genome-wide molecular phylogenetic analyses and mating experiments which reveal the evolutionary history and an intermediate stage of speciation of a giant water bug
<p>The intermediate stages of speciation are important for understanding the processes involved in the creation of biodiversity, and also comprise a number of interesting phenomena. However, difficulties are associated with dividing clear speciation stages because speciation is a continuous process. Therefore, the elucidation of speciation is an interesting and important task in evolutionary biology. We herein present an example of a species in an intermediate stage of speciation using the giant water bug <i>Appasus japonicus</i> (Heteroptera, Belostomatidae) that was investigated using mating experiments and phylogenetic analyses of the mtDNA <i>COI</i> (658 bp) and 16S rRNA (435 bp) regions, and nDNA SSR (13 loci) and its genome-wide SNPs (11,241 SNPs). The results of our phylogenetic analyses based on their mtDNA dataset and the genome-wide SNPs dataset strongly supported the paraphyly of the Japanese populations. Therefore, it is suggested that their ancestral lineage which being distributed in the Japanese Archipelago subsequently migrated to the Eurasian Continent (i.e., "back-dispersal" occurred). Furthermore, the results of the mating experiments suggested that among <i>A. japonicus</i>, even between closely related lineages, pre-mating reproductive isolation has been established by the differentiation of copulatory organ morphologies. In contrast, pre-mating reproductive isolation is not established in the absence of the differentiation of copulatory organ morphologies, even if genetic differentiation is prominent. These results suggested that their phylogenetic distance does not predict pre-mating reproductive isolation. Furthermore, in the present study, we present a clear example of pre-mating reproductive isolation driving speciation between closely related lineages.</p>
FIGURES 440–443. Form intermediate between Kimminsula taprobanes and K in Review of the Kimminsula-complex (Ephemeroptera, Leptophlebiidae)
FIGURES 440–443. Form intermediate between Kimminsula taprobanes and K. fasciata, larvae.
FIGURES 474–475. Form intermediate between Kimminsula taprobanes and K in Review of the Kimminsula-complex (Ephemeroptera, Leptophlebiidae)
FIGURES 474–475. Form intermediate between Kimminsula taprobanes and K. fasciata, egg.
Supplementary material 5 from: Wongpim T, Komsuwan J, Janmanee C, Thongchot P, Limsampan S, Wichiannarat N, Chaowatut W, Suwanrat S, Dechruksa W, Veeravechsukij N, Glaubrecht M, Krailas D (2023) Freshwater pulmonate snails and their potential role as trematode intermediate host in a cercarial dermatitis outbreak in Southern Thailand. Evolutionary Systematics 7(2): 293-315. https://doi.org/10.3897/evolsyst.7.107847
Some characters of Schistosoma spindale found in this study and the reference sources
Supplementary material 6 from: Wongpim T, Komsuwan J, Janmanee C, Thongchot P, Limsampan S, Wichiannarat N, Chaowatut W, Suwanrat S, Dechruksa W, Veeravechsukij N, Glaubrecht M, Krailas D (2023) Freshwater pulmonate snails and their potential role as trematode intermediate host in a cercarial dermatitis outbreak in Southern Thailand. Evolutionary Systematics 7(2): 293-315. https://doi.org/10.3897/evolsyst.7.107847
Some characters of Clinostomum giganticum found in this study and the reference sources
Supplementary material 4 from: Wongpim T, Komsuwan J, Janmanee C, Thongchot P, Limsampan S, Wichiannarat N, Chaowatut W, Suwanrat S, Dechruksa W, Veeravechsukij N, Glaubrecht M, Krailas D (2023) Freshwater pulmonate snails and their potential role as trematode intermediate host in a cercarial dermatitis outbreak in Southern Thailand. Evolutionary Systematics 7(2): 293-315. https://doi.org/10.3897/evolsyst.7.107847
Some characters of Schistosoma indicum found in this study and the reference sources
Supplementary material 2 from: Wongpim T, Komsuwan J, Janmanee C, Thongchot P, Limsampan S, Wichiannarat N, Chaowatut W, Suwanrat S, Dechruksa W, Veeravechsukij N, Glaubrecht M, Krailas D (2023) Freshwater pulmonate snails and their potential role as trematode intermediate host in a cercarial dermatitis outbreak in Southern Thailand. Evolutionary Systematics 7(2): 293-315. https://doi.org/10.3897/evolsyst.7.107847
Some characters of Echinostoma spiniferum found in this study and the reference sources
Supplementary material 3 from: Wongpim T, Komsuwan J, Janmanee C, Thongchot P, Limsampan S, Wichiannarat N, Chaowatut W, Suwanrat S, Dechruksa W, Veeravechsukij N, Glaubrecht M, Krailas D (2023) Freshwater pulmonate snails and their potential role as trematode intermediate host in a cercarial dermatitis outbreak in Southern Thailand. Evolutionary Systematics 7(2): 293-315. https://doi.org/10.3897/evolsyst.7.107847
Some characters of Echinostoma revolutum found in this study and the reference sources
Supplementary material 1 from: Wongpim T, Komsuwan J, Janmanee C, Thongchot P, Limsampan S, Wichiannarat N, Chaowatut W, Suwanrat S, Dechruksa W, Veeravechsukij N, Glaubrecht M, Krailas D (2023) Freshwater pulmonate snails and their potential role as trematode intermediate host in a cercarial dermatitis outbreak in Southern Thailand. Evolutionary Systematics 7(2): 293-315. https://doi.org/10.3897/evolsyst.7.107847
Some characters of Echinoparyphium recurvatum found in this study and the reference sources
Study of Vitespen (HSPPC-96, Oncophage ®) for Immune Response Assessment in Participants With Resectable Renal Cell Carcinoma at Intermediate Risk of Recurrence
ClinicalTrials.gov study NCT01147536. IPD Sharing: Not stated. Countries: 2. Publications: 0.
CTLA-4 /PD-L1 Blockade Following Transarterial Chemoembolization (DEB-TACE) in Patients With Intermediate Stage of HCC (Hepatocellular Carcinoma) Using Durvalumab and Tremelimumab
ClinicalTrials.gov study NCT03638141. IPD Sharing: UNDECIDED. Countries: 1. Publications: 0.
HD11 for Intermediate Stages
ClinicalTrials.gov study NCT00264953. IPD Sharing: Not stated. Countries: 0. Publications: 3.
Catheter Directed Therapy in Intermediate Risk Pulmonary Embolism Patients
ClinicalTrials.gov study NCT05612854. IPD Sharing: NO. Countries: 0. Publications: 4.
Mechanical Insufflation-Exsufflation Compared With CPAP in Patients Admitted to an Intermediate Care Unit With Pneumonia
ClinicalTrials.gov study NCT03714321. IPD Sharing: UNDECIDED. Countries: 0. Publications: 10.
Three Intraocular Lenses Designed to Improve Distance, Intermediate and Near Vision Following Lens Extraction
ClinicalTrials.gov study NCT01225952. IPD Sharing: Not stated. Countries: 1. Publications: 0.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.