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ShareScore release 0.9.0
Dataset results
758 results for “Candida”
Transcriptomic and Metabolomic Analysis Revealed Roles of Yck2 in Carbon Metabolism and Morphogenesis of Candida albicans
GEO Series GSE138069. Candida albicans SC5314. 6 samples. Type: Expression profiling by high throughput sequencing.
Transcriptional profile of Candida albicans bcr1 knockout.
GEO Series GSE33460. Candida albicans. 4 samples. Type: Expression profiling by array.
A network of paralogous stress response transcription factors in the human pathogen Candida glabrata
GEO Series GSE77904. Nakaseomyces glabratus. 22 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Candida lusitaniae ime2Δ/ime2Δ a/alpha WT meiosis
GEO Series GSE51789. Clavispora lusitaniae ATCC 42720; Clavispora lusitaniae. 12 samples. Type: Expression profiling by array.
Combining Genome-wide Gene Expression Analysis (RNA-seq) and Gene Editing Platform (CRISPR-Cas9) to Uncover the Selectively Pro-oxidant Activity of Aurone Compound against Candida albicans
GEO Series GSE158472. Candida albicans. 9 samples. Type: Expression profiling by high throughput sequencing.
Candida auris-macrophage cellular interactions and transcriptional response
GEO Series GSE236004. Candidozyma auris. 6 samples. Type: Expression profiling by high throughput sequencing.
Iron Chelator Deferasirox Reduces Candida albicans Invasion of Oral Epithelial Cells and Infection Levels in Murine Oropharyngeal Candidiasis
GEO Series GSE123277. Candida albicans. 4 samples. Type: Expression profiling by high throughput sequencing.
Transcriptional profile of Candida albicans during Hypoxic conditions.
GEO Series GSE24073. Candida albicans. 8 samples. Type: Expression profiling by array.
Transcriptional profiling and comparative genomic analysis of an invasive and non-invasive strain of Candida albicans
GEO Series GSE10689. Candida albicans. 2 samples. Type: Genome variation profiling by array.
Candida lusitaniae haploid nutrition
GEO Series GSE51790. Clavispora lusitaniae ATCC 42720; Clavispora lusitaniae. 10 samples. Type: Expression profiling by array.
Genome-wide expression profile analysis of the Candida glabrata Pdr1 regulon
GEO Series GSE24168. Nakaseomyces glabratus. 16 samples. Type: Expression profiling by array.
ChIP-Seq analysis of Candida albicans Sfl1p and Sfl2p
GEO Series GSE42886. Candida albicans. 8 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Total transcriptome analysis of Candida auris planktonic cells exposed to tyrosol
GEO Series GSE223953. Candidozyma auris. 6 samples. Type: Expression profiling by high throughput sequencing.
Transcriptional response of Candida albicans to oral epithelial cells
GEO Series GSE5340. Candida albicans. 18 samples. Type: Expression profiling by array.
Azole Resistance Mechanism in Candida glabrata Oropharyngeal Isolates
GEO Series GSE21352. Nakaseomyces glabratus. 35 samples. Type: Expression profiling by array.
Genomic level analysis of Upc2A-regulated transcription in Candida glabrata
GEO Series GSE182516. Nakaseomyces glabratus; Nakaseomyces glabratus CBS 138. 28 samples. Type: Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by high throughput sequencing.
Role of a Candida albicans Whi5/Nrm1 homolog in cell cycle and hyphal-specific gene expression
GEO Series GSE20612. Candida albicans. 4 samples. Type: Expression profiling by array.
Natural variation in phenotypic impact of Candida albicans cyclin gene HGC1
GEO Series GSE198594. Candida albicans. 12 samples. Type: Expression profiling by high throughput sequencing.
Candida albicans response to spaceflight (NASA STS-115)
This study presents the first global transcriptional profiling and phenotypic characterization of the major human opportunistic fungal pathogen, Candida albicans, grown in spaceflight conditions. Microarray analysis revealed that C. albicans subjected to short-term spaceflight culture differentially regulated 454 genes compared to synchronous ground controls, which represented 8.4% of the analyzed ORFs. Spaceflight-cultured C. albicans induced genes involved in cell aggregation (similar to flocculation), which was validated by microscopic and flow cytometry analysis. We also observed enhanced random budding of spaceflight-cultured cells as opposed to more normal bipolar budding patterns for ground samples, in accordance with the gene expression data. Furthermore, genes involved in antifungal agent and stress resistance were differentially regulated in spaceflight, including induction of ABC transporters and members of the major facilitator family, downregulation of ergosterol-encoding genes, and upregulation of genes involved in oxidative stress resistance. Finally, downregulation of genes involved in the actin cytoskeleton was observed. Interestingly, the transcriptional regulator Cap1 and over 30% of the Cap1 regulon was differentially expressed in spaceflight-cultured C. albicans. A potential role for Cap1 in the spaceflight response of C. albicans is suggested, as this regulator is involved in random budding, cell aggregation, actin cytoskeleton, and oxidative stress resistance; all related to observed spaceflight-associated changes of C. albicans. While culture of C. albicans in microgravity potentiates a global change in gene expression that could induce a virulence-related phenotype, no increased virulence in a murine intraperitoneal (i.p.) infection model was observed. This study represents an important basis for the assessment of the risk that commensal flora could play during spaceflight missions. Furthermore, since the low fluid-shear environment of microgravity is relevant to physical forces encountered by pathogens during the infection process, insights gained from this study could identify novel infectious disease mechanisms, with downstream benefits for the general public. Cells were grown for 24 hours on the space shuttle or as ground-based controls, preserved in RNALater, and stored at -80C. Four samples of each flight- and ground-based controls were harvested for microarray analysis. GAP is Group Activation Pack and each GAP contains 8 FPAs. The numbers represent the # assigned to the particular GAP and the number assigned to the specific FPA (1-8) within the indicated GAP. The same hardware is used for the flight samples and the ground samples.
A E- GEOD-50881 Gene Chip Assay --- Candida albicans response to spaceflight (NASA STS-115) API
A fully queryable REST API with JSON, XML, and CSV output as well as inline, runable examples using data from the transcriptional profiling and phenotypic characterization of the major human opportunistic fungal pathogen, Candida albicans, grown in spaceflight conditions.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.