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2,009 results for “Disruption”

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geo24/100

Loss of STIM1/2 in salivary glands disrupts ANO1 function but does not induce Sjögren’s syndrome.

GEO Series GSE251691. Mus musculus. 15 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenFeb 2025View details →
geo24/100

Disruption of the Integrator complex triggers the Integrated Stress Response through formation of double-stranded RNA [TTseq]

GEO Series GSE267040. Homo sapiens. 18 samples. Type: Other.

openGEO-OpenApr 2025View details →
geo24/100

A germline ETV6 mutation disrupts hematopoiesis via de novo creation of a nuclear export signal

GEO Series GSE288171. Mus musculus. 12 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenApr 2025View details →
geo24/100

A BRCA1 coiled-coil domain variant disrupting PALB2 interaction predisposes to mammary tumors with a targetable defect in homologous recombination repair [RNA-seq]

GEO Series GSE182448. Mus musculus. 73 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenFeb 2022View details →
geo24/100

Targeting Menin disrupts the KMT2A/B and polycomb balance to paradoxically activate bivalent genes [CRISPR]

GEO Series GSE181818. Homo sapiens. 5 samples. Type: Other.

openGEO-OpenJan 2023View details →
geo24/100

Glia detect and transiently protect against dendrite substructure disruption

GEO Series GSE282640. Caenorhabditis elegans. 12 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenDec 2024View details →
geo24/100

Transcriptomic analysis of a putative LysR family regulator, a putative Dps, and a cystine importer disrupted mutants in radiation resistant bacterium Deinococcus geothermalis

GEO Series GSE151903. Deinococcus geothermalis DSM 11300. 4 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenJun 2020View details →
geo24/100

Transcriptomic and epigenetic disruptions in excitatory neurons in Dnmt3a conditional knockout mouse

GEO Series GSE141587. Mus musculus. 49 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing; Other; Methylation profiling by high throughput sequencing.

openGEO-OpenMay 2022View details →
geo24/100

Omics analyses of mouse constitutive androstane receptor (CAR) ligand TCPOBOP effects in humanized mice reveal off-target lipid metabolism disruption

GEO Series GSE186654. Mus musculus. 16 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenJan 2022View details →
geo24/100

Male autism spectrum disorder is linked to brain aromatase disruption by prenatal BPA in multimodal investigations and 10HDA ameliorates the related mouse phenotype (BPA)

GEO Series GSE266401. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenMay 2024View details →
geo24/100

Persistent JunB Activation in Fibroblasts Disrupts Stem Cell Niche Interactions Enforcing Skin Aging [ATAC-seq]

GEO Series GSE180007. Mus musculus. 4 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.

openGEO-OpenJul 2021View details →
geo24/100

Disruption of H3K27me3 through loss of EZH1 and EZH2 accelerates progression of hepatosteatosis to fatal liver fibrosis

GEO Series GSE53627. Mus musculus. 21 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.

openGEO-OpenDec 2013View details →
geo24/100

WIN site inhibition disrupts a subset of WDR5 function

GEO Series GSE183781. Homo sapiens. 38 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing; Other.

openGEO-OpenFeb 2022View details →
geo24/100

TAS1440, an LSD1 Inhibitor, Disrupts the INSM1-LSD1 Complex to Activate Tumor-Suppressive Pathways via Transcriptional Reprogramming in Neuroendocrine SCLC [RNA-seq]

GEO Series GSE272002. Homo sapiens. 324 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenJan 2026View details →
geo24/100

Loss of cyclin A2 in murine colonic epithelial cells disrupts colon homeostasis by triggering DNA damage and dysplasia and high cyclin A2 expression is a good-prognosis factor in patients with colorec

GEO Series GSE149716. Mus musculus. 8 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenDec 2020View details →
geo24/100

Characterization of effects of estrogen, progesterone and the endocrine-disrupting chemicals on mouse mammary gland in 4-vinylcyclohexene diepoxide-induced menopause model via single-cell RNA-sequenci

GEO Series GSE191219. Mus musculus. 12 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenFeb 2022View details →
geo24/100

Targeted disruption of BMAL1 in the peripheral reproductive axis results in infertility in female mice

GEO Series GSE48758. Mus musculus. 56 samples. Type: Expression profiling by array.

openGEO-OpenOct 2014View details →
geo24/100

Disruption of pancreatic stellate cell myofibroblast phenotype promotes pancreatic tumour invasion.

GEO Series GSE189027. Mus musculus. 11 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenNov 2021View details →
geo24/100

TREX tetramer disruption alters RNA processing necessary for corticogenesis in THOC6 Intellectual Disability Syndrome

GEO Series GSE245121. Homo sapiens; Mus musculus. 23 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenOct 2023View details →
geo24/100

Disrupted Energy Metabolism is Associated with Retinal Ganglion Cell Degeneration in Autosomal Dominant Optic Atrophy

GEO Series GSE292269. Mus musculus. 3 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenJan 2026View details →

ScienceDex guides

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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.

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Allen Brain Atlas

Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.

allen-brain-atlas
neuroscienceopenDocumentation, web resources, and API references are available online.
Last verified 2026-04-30Open record

Annotated Behaviour and Observability Dataset (ABODe)

ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.

abode-home-cage
behavioral-neuroscienceopenThe DataShare record exposes download links for annotations, documentation, license text, and the zipped per-snippet data directory.
Last verified 2026-04-30Open record

DANDI Archive for NWB datasets

DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.

dandi-nwb
electrophysiologyopenPublished Dandiset metadata and archive endpoints are available through the production DANDI API.
Last verified 2026-04-30Open record

International Brain Laboratory public data

The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.

ibl
behavioral-neuroscienceopenPublic sessions can be searched and loaded from the IBL public data server through ONE.
Last verified 2026-04-29Open record

OpenNeuro

OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.

openneuro
neuroscienceopenPublished datasets are available on demand over the internet.
Last verified 2026-04-29Open record

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