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Dataset results
1,335 results for “Oxidative stress.”
Iron-induced oxidative stress alters the transcriptome of bronchoalveolar lavage cells in silicosis
GEO Series GSE264182. Homo sapiens. 19 samples. Type: Expression profiling by high throughput sequencing.
Modulation of cell metabolic pathways and oxidative stress signaling contribute to acquired melphalan resistance in multiple myeloma cells
GEO Series GSE60970. Homo sapiens. 24 samples. Type: Expression profiling by array.
Gene-environment interaction between Notch1 and oxidative stress disrupts cardiac developmental pathways
GEO Series GSE279323. Homo sapiens. 12 samples. Type: Expression profiling by high throughput sequencing.
High-throughput Fitness Experiments Reveal Specific Vulnerabilities of Human-Adapted Salmonella During Stress and Infection- Barseq4 (InSPI2, hydrogen peroxide (H2O2), nitric oxide (NO), sodium hypoch
GEO Series GSE261860. Salmonella enterica subsp. enterica serovar Paratyphi A str. ATCC 9150; Salmonella enterica subsp. enterica serovar Typhimurium str. D23580; Salmonella enterica subsp. enterica serovar Typhimurium str. ST4/74; Salmonella enterica subsp. enterica serovar Typhi str. Ty2. 40 samples. Type: Other.
R. sphaeroides delta-cryB vs. R. sphaeroides 2.4.1 photo-oxidative stress, aerobic conditions
GEO Series GSE33553. Cereibacter sphaeroides 2.4.1. 2 samples. Type: Expression profiling by array.
Nrf2-mediated enhancer activation ameliorates oxidative stress and cystogenesis in autosomal dominant polycystic kidney disease
GEO Series GSE141741. Homo sapiens. 30 samples. Type: Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by high throughput sequencing.
Protective effect of mesaconate on autoimmune hepatitis via suppression of inflammatory response and oxidative stress
GEO Series GSE289607. Mus musculus. 9 samples. Type: Expression profiling by high throughput sequencing.
Genome-wide analysis of transfection of miR-141 or miR-200c in murine fibroblasts subjected to acute oxidative stress
GEO Series GSE26113. Mus musculus. 4 samples. Type: Expression profiling by array.
LncRNA Tuna is activated in cadmium-induced placental insufficiency and drives the NRF2-mediated oxidative stress response [human Jeg3]
GEO Series GSE233281. Homo sapiens. 16 samples. Type: Expression profiling by high throughput sequencing.
A role for the RNA Polymerase II-CTD phosphatase, FCP1 in the oxidative stress response
GEO Series GSE128936. Saccharomyces cerevisiae. 16 samples. Type: Expression profiling by array.
Genomic profiles of oxidative stress-induced rat renal cell carcinomas
GEO Series GSE36101. Rattus norvegicus. 16 samples. Type: Expression profiling by array.
Data from: Human macular Müller cells rely more on serine biosynthesis to combat oxidative stress than those from the periphery
The human macula is more susceptible than the peripheral retina to developing blinding conditions such as age-related macular degeneration, diabetic retinopathy. A key difference between them may be the nature of their Müller cells. We found primary cultured Müller cells from macula and peripheral retina display significant morphological and transcriptomic differences. Macular Müller cells expressed more Phosphoglycerate Dehydrogenase (PHGDH, a rate-limiting enzyme in serine synthesis) than peripheral Müller cells. The serine synthesis, glycolytic and mitochondrial function were more activated in macular than peripheral Müller cells. Serine biosynthesis is critical in defending against oxidative stress. Intracellular reactive oxygen species and glutathione levels were increased in primary cultured macular Müller cells which were more susceptible to oxidative stress after inhibition of PHGDH. Our findings indicate serine biosynthesis is a critical part of the macular defence against oxidative stress and suggest dysregulation of this pathway as a potential cause of macular pathology.
Wedelolactone facilitates the development of porcine early embryo by reducing the oxidative stress
<p>Wedelolactone (WDL) is a couma ether compound extracted from the traditional Chinese medicinal plant, Eclipta prostrata. It is a natural polyphenol that exhibits a variety of pharmacological activities, such as anti-inflammatory, anti-free radical scavenging, and antioxidant activities in the bone, brain, and ovary. However, its effect on embryonic development remains unknown. The present study explored the influence of WDL supplementation on porcine oocytes culture in vitro, its underlying mechanisms, and the levels of Kelch-like ECH-associated protein 1/nuclear factor-erythroid 2-related factor 2/antioxidant response element. The results showed that WDL (2.5 nM) significantly increased the blastocyst formation rate, mitochondrial activity, and proliferation ability, while reducing the reactive oxygen species accumulation, apoptosis, and autophagy.</p>
Figure 1 from: Kokanova-Nedialkova Z, Aluani D, Tzankova V, Nedialkov P (2021) Simultaneous quantification of the major flavonoids from wild spinach by UHPLC-HRMS and their neuroprotective effects in a model of H2O2-induced oxidative stress on SH-SY5Y cells. Pharmacia 68(3): 657-664. https://doi.org/10.3897/pharmacia.68.e71030
Figure 1 A chromatogram of the standard mixture of flavonoids.
Coumarin–Chalcone Hybrid LM-021 and Indole Derivative NC009-1 Targeting Inflammation and Oxidative Stress in Par-kinson's Disease Cell Models
<p>Figure S1: Wild type and A53T SNCA-GFP BE(2)-M17 cells; Figure S2: α-Synuclein aggregation and neurite outgrowth analyses on wild type and A53T SNCA-GFP BE(2)-M17 cells; Figure S3: Neuroprotective effects of LM-021 and NC009-1 on A53T-11 SNCA-GFP BE(2)-M17 cells; Figure S4: α-Synuclein aggregation reduction and neurite outgrowth promotion of LM-021 and NC009-1 on A53T-11 SNCA-GFP BE(2)-M17 cells.</p>
Effects of Empagliflozin in Reducing Oxidative Stress After Kidney Transplantation
ClinicalTrials.gov study NCT04918407. IPD Sharing: NO. Countries: 1. Publications: 0.
Evolution of Oxidative Stress in Coronary Patients With Moderate Sleep Apnea Syndrome After Treatment With Continuous Positive Airway Pressure
ClinicalTrials.gov study NCT02893865. IPD Sharing: NO. Countries: 1. Publications: 0.
Finerenone and Renal Oxidative Stress
ClinicalTrials.gov study NCT06244758. IPD Sharing: NO. Countries: 1. Publications: 0.
Effect of Hyperbaric Therapy on Markers of Oxidative Stress in Children With Autism
ClinicalTrials.gov study NCT00263367. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Effects of Propofol on Oxidative Stress and Liver Regeneration After Partial Hepatectomy
ClinicalTrials.gov study NCT00219856. IPD Sharing: Not stated. Countries: 1. Publications: 0.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.