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674 results for “brain disease”

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geo16/100

Subtle changes in brain expression modules in Alzheimer’s disease TREM2 carriers compared to non-carriers

GEO Series GSE140841. Homo sapiens. 133 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenOct 2025View details →
geo16/100

Gene expression profiling of the whole brain of the normal littermate control for Huntington disease model mouse R6/2 at 5 weeks post-natal age using transcriptome tomography

GEO Series GSE227658. Mus musculus. 43 samples. Type: Expression profiling by array.

openGEO-OpenDec 2025View details →
geo16/100

Transcriptomic profiling identifies CD8+ T-cells in the brain of aged and Alzheimer’s disease transgenic mice as tissue-resident memory T-cells

GEO Series GSE180746. Mus musculus. 17 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenAug 2022View details →
geo16/100

Staging Alzheimer’s disease in brains and retinas of APP/PSEN1 mice by transcriptional profiling

GEO Series GSE136861. Mus musculus. 81 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenNov 2019View details →
geo16/100

Transcriptomic profiling of Alzheimer's disease and high-fat diet-induced exacerbation in mouse brain

GEO Series GSE302476. Rattus norvegicus. 12 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenJul 2025View details →
geo16/100

Characterizing the metabolomes of microglia, astrocytes, and neurons in the brain across states of health, aging, and disease

GEO Series GSE316928. Mus musculus. 35 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenFeb 2026View details →
geo16/100

Gene expression changes across multiple regions of the Parkinson’s disease brain

GEO Series GSE28894. Homo sapiens. 114 samples. Type: Expression profiling by array.

openGEO-OpenJul 2011View details →
geo16/100

Comprehensive gene expression analysis of Huntington disease model mouse brains using Transcriptome Tomography

GEO Series GSE228206. Mus musculus. 85 samples. Type: Expression profiling by array.

openGEO-OpenDec 2025View details →
geo16/100

Designed macrocyclic peptide rescues behavioral impairment and brain pathology in an Alzheimer’s disease mouse model

GEO Series GSE246244. Mus musculus. 71 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenSep 2025View details →
geo16/100

Gpr124 is essential for blood-brain barrier integrity in central nervous system disease

GEO Series GSE74052. Mus musculus. 21 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenMar 2017View details →
geo16/100

Identification of altered blood microRNAs in a rat model of Parkinson’s disease by Custom "Brain Specific miRNA" Open Array Real-time PCRpanel

GEO Series GSE180996. Rattus norvegicus. 6 samples. Type: Non-coding RNA profiling by array.

openGEO-OpenJul 2021View details →
geo16/100

mRNA sequencing of brain and liver in multiple Alzheimer's Disease mouse models after treatment with either a Non-Targeting Control siRNA or an siRNA targeting mouse Apoe mRNA

GEO Series GSE186756. Mus musculus. 89 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenOct 2023View details →
geo16/100

Patient iPSC-derived brain organoids of neuronopathic Gaucher disease identify imbalances in neural lineages and deficits in interneuron function

GEO Series GSE300486. Homo sapiens. 2 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenFeb 2026View details →
geo16/100

Tumor lineage-specific immune response in brain metastatic disease: opportunities for targeted immunotherapy regimen?

GEO Series GSE227427. Homo sapiens. 22 samples. Type: Other.

openGEO-OpenFeb 2024View details →
geo16/100

Brain regional and cell type-specific chromatin changes among sporadic, GBA1 variant, and APOE E4 Parkinson’s Disease

GEO Series GSE273511. Homo sapiens. 426 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.

openGEO-OpenJul 2024View details →
geo16/100

bacTRAP profiling of astrocytes in five mouse brain regions in wildtype controls and hippocampus region in a Alzheimer's disease mouse model

GEO Series GSE310518. Mus musculus. 30 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenDec 2025View details →
geo16/100

RNA-Binding Activity of PHGDH Drives Amyloid-beta Production in A Human Brain Organoid Model of Sporadic Alzheimer’s Disease

GEO Series GSE302314. Homo sapiens. 8 samples. Type: Other.

openGEO-OpenJan 2026View details →
geo16/100

Transcriptional profiling of brain tissues from a Q130 Long Evans Knock-in rat model of Huntington’s disease at 10-, 19- and 24-months of age

GEO Series GSE169386. Rattus norvegicus. 145 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenApr 2021View details →
geo16/100

Brain pathology and cerebellar Purkinje cell loss in a mouse model of chronic neuronopathic Gaucher disease [whole brain]

GEO Series GSE157987. Mus musculus. 17 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenNov 2020View details →
geo16/100

Gene expression profiling of the whole brain of the Huntington disease model mouse R6/2 at 5 weeks post-natal age using transcriptome tomography

GEO Series GSE227657. Mus musculus. 42 samples. Type: Expression profiling by array.

openGEO-OpenDec 2025View details →

ScienceDex guides

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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.

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Allen Brain Atlas

Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.

allen-brain-atlas
neuroscienceopenDocumentation, web resources, and API references are available online.
Last verified 2026-04-30Open record

Annotated Behaviour and Observability Dataset (ABODe)

ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.

abode-home-cage
behavioral-neuroscienceopenThe DataShare record exposes download links for annotations, documentation, license text, and the zipped per-snippet data directory.
Last verified 2026-04-30Open record

DANDI Archive for NWB datasets

DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.

dandi-nwb
electrophysiologyopenPublished Dandiset metadata and archive endpoints are available through the production DANDI API.
Last verified 2026-04-30Open record

International Brain Laboratory public data

The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.

ibl
behavioral-neuroscienceopenPublic sessions can be searched and loaded from the IBL public data server through ONE.
Last verified 2026-04-29Open record

OpenNeuro

OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.

openneuro
neuroscienceopenPublished datasets are available on demand over the internet.
Last verified 2026-04-29Open record