Find research datasets worth reusing
Search datasets from major research repositories and use ShareScore to quickly assess how well each record supports discovery, access, and reuse.
1,923
datasets available to search
ShareScore release 0.9.0
Dataset results
1,923 results for “compounds”
Fig. 5 in Isolation of CFTR and TMEM16A inhibitors from Neorautanenia mitis (A. Rich) Verdcourt: Potential lead compounds for treatment of secretory diarrhea
Fig. 5. Validation of TMEM16A activation in Calu-3 cells. (A) Representative traces of change in Cl current induced by 10 μM Eact with or without 10 μM MONNA pretreatment. (B) Data were fitted to the Hill equation and expressed as means of Eact-induced Cl current (mean ± S.E.M, n = 3). ***P <0.001.
Fig. 3 in Isolation of CFTR and TMEM16A inhibitors from Neorautanenia mitis (A. Rich) Verdcourt: Potential lead compounds for treatment of secretory diarrhea
Fig. 3. Inhibitory effects of compounds 2, 6, 7 and 10 on cAMP-induced chloride secretion in T84 cells. (A) Dose response studies of compounds 2, 6, 7 and 10 on cAMP-induced chloride secretion. The representative traces of apical ISC on T84 cells are shown. (B) Data were fitted to the Hill equation and expressed as means of % forskolin-stimulated ISC ± S.E.M. (n = 3).
Fig. 7 in Isolation of CFTR and TMEM16A inhibitors from Neorautanenia mitis (A. Rich) Verdcourt: Potential lead compounds for treatment of secretory diarrhea
Fig. 7. Effect of compound 10 on CFTR-mediated apical IClˉ in T84 cells. (A) The representative trace of apical IClˉ stimulated by forskolin (20 μM), forskolin plus IBMX (100 μM) and CPT-cAMP (100 μM). (B) Data were fitted to the Hill equation and expressed as means of %agonist-stimulated IClˉ ± S.E.M. (n = 3).
Fig. 4 in Isolation of CFTR and TMEM16A inhibitors from Neorautanenia mitis (A. Rich) Verdcourt: Potential lead compounds for treatment of secretory diarrhea
Fig. 4. Inhibitory effects of ABAQ on cAMP-induced chloride secretion in T84 cells. (A) Dose response studies of ABAQ on cAMP-induced chloride secretion. The representative traces of apical ISC on T84 cells is shown. (B) Data were fitted to the Hill equation and expressed as means of %forskolin-stimulated ISC ± S.E.M. (n = 3).
Fig. 8 in Isolation of CFTR and TMEM16A inhibitors from Neorautanenia mitis (A. Rich) Verdcourt: Potential lead compounds for treatment of secretory diarrhea
Fig. 8. No involvement of protein phosphatase and MRP4 in the inhibition of CFTR chloride channel activity by compound 10 (A) Representative trace of apical IClˉ stimulation after pretreatment with Na3VO4 (protein phosphatase inhibitor; 1 mM) and MK571 (MRP4 inhibitor; 20 μM). (B) Data were fitted to the Hill equation and expressed as means of %forskolin-stimulated IClˉ ± S.E.M. (n = 3).
Fig. 6. ABDCM dose-dependently inhibited TMEM16A in Isolation of CFTR and TMEM16A inhibitors from Neorautanenia mitis (A. Rich) Verdcourt: Potential lead compounds for treatment of secretory diarrhea
Fig. 6. ABDCM dose-dependently inhibited TMEM16A in Calu-3 cells. (A) Representative trace of change in Cl current. ABDCM at indicated concentration were applied 20 min prior to TMEM16A activation by Eact (10 μM). (B) Dose-response relationship of TMEM16A inhibition by ABDCM. Data were fitted to the Hill equation and expressed as means of Eact-induced Cl current (mean ± S.E.M, n = 3).
Supplementary Tables: 14C dating and Compound Specific Radiocarbon Analyses
<p>The two Supplementary Tables contain results from <sup>14</sup>C dating and Compound Specific Radiocarbon Analysis (CSRA) carried out on long chain Fatty Acid Methyl Esters (FAMEs).</p>
Biomimetic Dispersive Solid-Phase Microextraction as a Novel Concept for High-Throughput Estimation of Human Oral Absorption of Organic Compounds
<p>Statistical data of the fourteen <em>in-vitro </em>MLR models evaluated for the prediction of the effective permeability of organic compounds across the human intestine, presented in Table S1 and Table 2 of the article Analytical Chemistry, 95, 2023, 13123−13131. <br> (DOI: 10.1021/acs.analchem.3c01749)</p>
Compounding seasonal variations in outlet glacier dynamics revealed by high-resolution observations
<p>It contains the code, terminus data, flowlines, and hybridDEMs used in the paper titled "Compounding seasonal variations in outlet glacier dynamics revealed by high-resolution observations". </p>
Neutron diffraction data for Comparative study of the magnetism in Mn3RhGe and related compound Mn3IrSi
<p>Mn3RhGe_NPD.zip contains TOF neutron powder diffraction patterns collected in the temperature range of 1.5K-240K</p><p>Mn3IrSi_NPD.zip contains TOF neutron powder diffraction patterns collected in the temperature range of 5K-300K</p><p>journal_MnRhGe.pdf provides information about the NPD data collection temperature and run number</p><p>journal_MnIrSi.pdf provides information about the NPD data collection temperature and run number</p>
Analysis of Volatile Organic Compounds in Expired Air in Healthy Volunteers: Comparison of Three Mass Spectrometry Techniques for the Characterization of Volatolome in Clinical Studies
ClinicalTrials.gov study NCT06020521. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Bioavailability of Compounds From Different Bean Varieties in Healthy Individuals.
ClinicalTrials.gov study NCT02342340. IPD Sharing: Not stated. Countries: 1. Publications: 4.
Topical Compounded Pain Creams And Pain Perception (TOPCAPP)
ClinicalTrials.gov study NCT01862848. IPD Sharing: Not stated. Countries: 1. Publications: 6.
Efficacy and Safety of Fire Needle Therapy Combined With Cortex Phellodendri Compound Fluid Wet Compress for Acute Herpes Zoster: a Randomized Controlled Trial.
ClinicalTrials.gov study NCT06985589. IPD Sharing: NO. Countries: 1. Publications: 6.
Efficacy of Compound Betamethasone Injection Combined With Ropivacaine in Ultrasound-guided Thoracic Paravertebral Nerve Block for Chronic Post-thoracotomy Pain
ClinicalTrials.gov study NCT05175001. IPD Sharing: NO. Countries: 1. Publications: 4.
Effect of Supplementation of Bioactive Compounds on the Energy Metabolism of People Living With HIV / AIDS
ClinicalTrials.gov study NCT03141918. IPD Sharing: NO. Countries: 1. Publications: 3.
Effect of Adjuvant Treatment With Compound Cranberry Extract Tablets in Acute Bacterial Cystitis.
ClinicalTrials.gov study NCT00305071. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Repeat Dose Safety Study for Compound to Treat Hematologic Cancer
ClinicalTrials.gov study NCT00881946. IPD Sharing: Not stated. Countries: 3. Publications: 1.
A Randomized, Open-label, Two-way Crossover Study to Assess the Pharmacokinetics and Safety of CK-30 600 mg (Compound K)
ClinicalTrials.gov study NCT03136770. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Efficacy & Safety of SmofKabiven Emulsion for Infusion vs Hospital Compounded "All in One" for Parenteral Nutrition
ClinicalTrials.gov study NCT03792100. IPD Sharing: NO. Countries: 1. Publications: 22.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.