Find research datasets worth reusing
Search datasets from major research repositories and use ShareScore to quickly assess how well each record supports discovery, access, and reuse.
821
datasets available to search
ShareScore release 0.9.0
Dataset results
821 results for “epigenetic regulation”
Epigenetic landscapes in wild-type and dimer-mutant Notch regulated T-LL cells
GEO Series GSE72175. Homo sapiens. 4 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Characterization of Epigenetic Regulation in an Extraterrestrial Environment: The Arabidopsis Spaceflight Methylome
When germinated and grown on-board the ISS (International Space Station), plant do not exhibit abnormal structures but they do have altered growth habits and this project aims to investigate the molecular mechanisms that provide the foundation for the altered growth habits observed in orbit. APEX03-2 (Advanced Plant Experiment 03-2), also known as TAGES-ISA (Transgenic Arabidopsis Gene Expression System-Intracellular Signaling Architecture) specifically addresses the growth and molecular changes that occur in Arabidopsis thaliana plants during spaceflight by using molecular and genetic tools, and by asking fundamental questions regarding root structure, growth and cell wall remodeling may be answered. This investigation advances the fundamental understanding of the molecular biological responses to extraterrestrial environments. This understanding helps to further define the impacts of spaceflight on biological systems to better enable NASA's future space exploration goals.
Epigenetic regulation of SARS-Cov-2 spike protein modulates cellular viability and nascent RNA transcription in neuronal cells
GEO Series GSE220046. Homo sapiens. 9 samples. Type: Expression profiling by high throughput sequencing.
Dynamic regulation of the histone variant H1.0 contributes to intratumor epigenetic and functional heterogeneity [RNA-Seq]
GEO Series GSE65518. Homo sapiens. 24 samples. Type: Expression profiling by high throughput sequencing.
Disruption of the epigenetic regulator BAP1 drives chromatin remodeling leading to the emergence of cells with breast cancer stem cell properties and aberrant glycosylation [ATACseq_3D]
GEO Series GSE271682. Homo sapiens. 6 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
CDYL2 epigenetically regulates MIR124 to control NF-kB/STAT3-dependent breast cancer cell plasticity [MDA-MB-231 RNA-seq]
GEO Series GSE150319. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
5-hydroxymethylcytosines regulate gene expression as a passive DNA demethylation resisting epigenetic mark in proliferative somatic cells [RNA-Seq]
GEO Series GSE224393. Homo sapiens. 8 samples. Type: Expression profiling by high throughput sequencing.
Loss of epigenetic regulation disrupts lineage commitment and promotes breast cancer (scRNA-Seq)
GEO Series GSE178423. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
NSD2 Drives Podocyte Injury in Diabetic Kidney Disease via Epigenetic Regulation of Hippo Signaling
GEO Series GSE311115. Mus musculus. 16 samples. Type: Expression profiling by high throughput sequencing.
The H3K27M mutation alters stem cell growth, epigenetic regulation, and differentiation potential
GEO Series GSE159071. Homo sapiens. 62 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing; Methylation profiling by high throughput sequencing.
Perturbed epigenetic transcriptional regulation in AML with IDH mutations causes increased susceptibility to NK cells [TT-Seq]
GEO Series GSE207830. Homo sapiens. 24 samples. Type: Expression profiling by high throughput sequencing.
Extracellular matrix glycation epigenetically regulates brain aging and neurodegeneration in the in vitro aged neurovascular model
GEO Series GSE278799. Homo sapiens. 7 samples. Type: Expression profiling by high throughput sequencing.
Epigenetic competition reveals density-dependent regulation and target site plasticity of phosphorothioate epigenetics in bacteria
GEO Series GSE135949. Escherichia coli K-12; Escherichia coli BW25113; Salmonella enterica. 39 samples. Type: Genome binding/occupancy profiling by high throughput sequencing; Other; Expression profiling by high throughput sequencing.
Loss of epigenetic regulation disrupts lineage commitment and promotes breast cancer
GEO Series GSE178424. Mus musculus. 34 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.
IFN-γ and IL-4 regulate epigenetic modifiers in macrophages
GEO Series GSE83957. Homo sapiens. 24 samples. Type: Expression profiling by array.
ABCA1-eRNA as a novel Epigenetic Regulator, promotes cholesterol efflux, Attenuates Macrophage Inflammation and Severity of Coronary Artery Disease [ABCA1 RNA-seq]
GEO Series GSE192939. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
Perturbed epigenetic transcriptional regulation in AML with IDH mutations causes increased susceptibility to NK cells
GEO Series GSE207831. Homo sapiens. 56 samples. Type: Methylation profiling by array.
CDYL2 epigenetically regulates MIR124 to control NF-kB/STAT3-dependent breast cancer cell plasticity [RNA-seq]
GEO Series GSE150306. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
Myc-mediated SDHA Acetylation Triggers Epigenetic Regulation of Gene Expression and Tumorigenesis
GEO Series GSE124255. Homo sapiens. 13 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.
Specific exercise patterns generate an epigenetic molecular memory window that drives long-term memory formation and identifies ACVR1C as a bidirectional regulator of memory
GEO Series GSE208615. Mus musculus. 70 samples. Type: Expression profiling by high throughput sequencing.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.