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663
datasets available to search
ShareScore release 0.9.0
Dataset results
663 results for “tumor targeting”
Targeting redox-sensitive MBD2-NuRD condensate for tumor therapy [ATAC-seq]
GEO Series GSE270303. Homo sapiens. 8 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Non-overlap of tumor acidosis and hypoxia: new rationale to target fatty acid desaturase activity in cancer.
GEO Series GSE250335. Homo sapiens. 12 samples. Type: Expression profiling by high throughput sequencing.
Wilms Tumor-1 (WT-1) and its candidate target genes in gliomagenesis
GEO Series GSE22578. Homo sapiens. 9 samples. Type: Expression profiling by array.
Targeting MLL methyltransferases enhance the anti-tumor effects of PI3K inhibition in hormone receptor-positive breast cancer
GEO Series GSE214333. Homo sapiens. 12 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.
Targeting MLL methyltransferases enhance the anti-tumor effects of PI3K inhibition in hormone receptor-positive breast cancer [Cut & Run]
GEO Series GSE214329. Homo sapiens. 6 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Potent anti-tumor immunity and reversal of CD8 T cell exhaustion by spatially and functionally targeting Treg cells in the tumor microenvironment
GEO Series GSE266362. Mus musculus. 9 samples. Type: Expression profiling by high throughput sequencing.
Disulfide-directed multicyclic peptides for chimeric antigen receptors targeting solid tumors
GEO Series GSE314995. Homo sapiens. 27 samples. Type: Expression profiling by high throughput sequencing.
Targeting MLL methyltransferases enhance the anti-tumor effects of PI3K inhibition in hormone receptor-positive breast cancer [RNA-Seq]
GEO Series GSE214331. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
Targeting redox-sensitive MBD2-NuRD condensate for tumor therapy [CUT&Tag]
GEO Series GSE270304. Homo sapiens. 4 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Hypoxia PET Imaging Identifies Immunosuppressive Tumor Microenvironments and Guides Targeted Evofosfamide Therapy to Rescue Checkpoint Blockade Refractory Tumors
GEO Series GSE184863. Mus musculus. 16 samples. Type: Expression profiling by array.
First-in-human study of the novel fibroblast activation protein-targeted 4-1BB agonist RO7122290 in patients with advanced solid tumors
GEO Series GSE212521. Homo sapiens. 34 samples. Type: Expression profiling by high throughput sequencing.
In Vivo Tumor Growth Control by General Control Nonderepressible 2 (GCN2) Targeting Agents Results from Kinase Activation
GEO Series GSE297227. Homo sapiens. 59 samples. Type: Expression profiling by high throughput sequencing.
MicroRNA-1 regulates goat uterine NK cells function by targeting tumor necrosis factor-like weak inducer of apoptosis (TWEAK)
GEO Series GSE144088. Capra hircus. 2 samples. Type: Non-coding RNA profiling by high throughput sequencing.
Combinational targeting CCL7 and Flt3L to promote the expansion and infiltration of cDC1 in tumors enhances T cell activation and anti-PD-1 therapy [Dendritic Cell]
GEO Series GSE225126. Mus musculus. 4 samples. Type: Expression profiling by high throughput sequencing.
Combinational targeting CCL7 and Flt3L to promote the expansion and infiltration of cDC1 in tumors enhances T cell activation and anti-PD-1 therapy [CD8 T]
GEO Series GSE225163. Mus musculus. 8 samples. Type: Expression profiling by high throughput sequencing.
TARGET: Kidney, Rhabdoid Tumor (RT)
To further explore some more aggressive subtypes in pediatric cancer already under study in OCG, CGCI is partnering with TARGET initiative to support extensive sequencing analysis of three hard to treat childhood cancers: refractory to treatment cases of acute myeloid leukemia and two rare kidney tumors; clear cell sarcoma of the kidney and rhabdoid tumor (RT). Rhabdoid tumors are a rare, very aggressive type of kidney tumor of infancy, and patients typically have a poor prognosis. Up to 40 patient cases of matched tumor and normal samples, as well as some established cell lines, will undergo whole genome sequencing, miRNA-seq and mRNA-seq, DNA methyl-seq and ChIP-seq to generate a comprehensive profile and hopefully facilitate the development of better therapeutic options for this tumor subtype.
TARGET: Kidney, Wilms Tumor (WT)
There are 130 fully characterized patient cases with high risk Wilms tumor (all tumor/normal pairs; 8 with additional samples for analysis = 3 with tumor adjacent normal, 5 with relapse sample) that will make up the TARGET WT dataset. Each case will have gene expression, tumor and paired normal copy number analyses, methylation and whole genome sequencing; a subset of WT cases with mRNA-seq, miRNA-seq, and whole exome sequencing data available as well.
Genetic engineered primary human natural killer cells targeting TIGIT via CRISPR/Cas9 enhanced anti-tumor activity against GBM spheroids and 2D culture.
GEO Series GSE212941. Homo sapiens. 2 samples. Type: Expression profiling by array.
miR-30-5p functions as a tumor suppressor by targeting BCL9
GEO Series GSE50422. Homo sapiens. 12 samples. Type: Expression profiling by array.
Targeting IRAK2 in triple-negative breast cancer cells decreases cellular growth in vitro and delays tumor progression in murine models
GEO Series GSE213228. Homo sapiens. 18 samples. Type: Expression profiling by high throughput sequencing.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.