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FIG. 4. — A, C, E in New data and species of Thecomyia Perty, 1833 (Diptera: Sciomyzidae) from Mitaraka (French Guiana), with notes on the genus
FIG. 4. — A, C, E, ♂ Thecomyia chrysacra Marinoni & Steyskal, 2003: A, habitus, lateral view; C, habitus, dorsolateral view; E, head, lateral view; B, D, F, ♂ holotype of Thecomyia diederiki Mortelmans n. sp.; B, habitus, lateral view; D, habitus, dorsolateral view; F, head, lateral view. Scale bars: 1 mm.
FIGURES 1–2. N. yaoluopingus 1 in New data of Nazeris Fauvel in Anhui, China (Coleoptera, Staphylinidae, Paederinae)
FIGURES 1–2. N. yaoluopingus 1. habitus; 2. forebody. Scale bars: 1 mm
FIGURE 5 in Description of the previously unknown sexes in four West African Lycaenidae (Lepidoptera) with new data on their distribution
FIGURE 5. Known localities of G. pacifica.
FIGURE 3 in Description of the previously unknown sexes in four West African Lycaenidae (Lepidoptera) with new data on their distribution
FIGURE 3. Known localities of Parasiomera alfa.
FIGURE 9 in Description of the previously unknown sexes in four West African Lycaenidae (Lepidoptera) with new data on their distribution
FIGURE 9. Known localities of P. mano.
FIGURE 7 in Description of the previously unknown sexes in four West African Lycaenidae (Lepidoptera) with new data on their distribution
FIGURE 7. Known localities of C. wingae.
FIGURE 13 in Three new species and DNA sequence data of the rare South American water beetle genus Adelphydraena Perkins, 1989 (Coleoptera: Hydraenidae)
FIGURE 13. Ventral habitus of Adelphydraena species.
FIGURE 7. Adelphydraena spinosa n in Three new species and DNA sequence data of the rare South American water beetle genus Adelphydraena Perkins, 1989 (Coleoptera: Hydraenidae)
FIGURE 7. Adelphydraena spinosa n. sp., habitus of holotype.
FIGURE 1 in Three new species and DNA sequence data of the rare South American water beetle genus Adelphydraena Perkins, 1989 (Coleoptera: Hydraenidae)
FIGURE 1. Dorsal habitus of Adelphydraena species.
FIGURE 4 in Three new species and DNA sequence data of the rare South American water beetle genus Adelphydraena Perkins, 1989 (Coleoptera: Hydraenidae)
FIGURE 4. Adelphydraena spangleri Perkins, habitus of non-type.
FIGURE 3 in Three new species and DNA sequence data of the rare South American water beetle genus Adelphydraena Perkins, 1989 (Coleoptera: Hydraenidae)
FIGURE 3. Adelphydraena orchymonti Perkins, habitus of non-type.
FIGURE 8. Adelphydraena surinamensis n in Three new species and DNA sequence data of the rare South American water beetle genus Adelphydraena Perkins, 1989 (Coleoptera: Hydraenidae)
FIGURE 8. Adelphydraena surinamensis n. sp., habitus of holotype.
FIGURE 2. Adelphydraena amazonica n in Three new species and DNA sequence data of the rare South American water beetle genus Adelphydraena Perkins, 1989 (Coleoptera: Hydraenidae)
FIGURE 2. Adelphydraena amazonica n. sp., habitus of holotype.
FIGURE 25 in Vietnamella chebalingensis, a new species of the family Vietnamellidae (Ephemeroptera) from China based on morphological and molecular data
FIGURE 25. Habitat of Vietnamella chebalingensis Tong, sp. nov.
FIGURE 2. Shell measurement protocol. H height L length W width. a in New taxonomic and phylogeographic data on three nominal species of the genus Septaria Férussac, 1807 (Gastropoda: Cycloneritida: Neritidae)
FIGURE 2. Shell measurement protocol. H height L length W width. a apex, ms muscle scar, s septum.
FIGURE 32 in An update of morphological and distributional data of the genus Patrera Simon (Araneae: Anyphaenidae: Anyphaeninae) with the description of twenty-five new species from Colombia
FIGURE 32. Distribution of species of the florezi group in Colombia.
FIGURE 31 in An update of morphological and distributional data of the genus Patrera Simon (Araneae: Anyphaenidae: Anyphaeninae) with the description of twenty-five new species from Colombia
FIGURE 31. Distribution of species of the fulvastra group in Colombia.
FIGURE 30 in An update of morphological and distributional data of the genus Patrera Simon (Araneae: Anyphaenidae: Anyphaeninae) with the description of twenty-five new species from Colombia
FIGURE 30. Distribution of species of the fulvastra group in Colombia.
FIGURE 33 in An update of morphological and distributional data of the genus Patrera Simon (Araneae: Anyphaenidae: Anyphaeninae) with the description of twenty-five new species from Colombia
FIGURE 33. Distribution of species of the philipi group in Colombia.
Data from: Daridorexant, a new dual orexin receptor antagonist in elderly subjects with insomnia disorder: a randomized clinical trial
<p><b>Objective:</b> To assess the dose-response of daridorexant, a new dual orexin receptor antagonist, on wake after sleep onset (WASO).</p> <p><b>Methods:</b> Elderly (≥65 years) subjects (n = 58) with insomnia were randomly allocated (Latin square design) to receive five treatments (5, 10, 25, and 50 mg daridorexant and placebo) during five treatment periods, each consisting of two treatment nights followed by a 5–12-day washout period. Main efficacy endpoints were the absolute change from baseline in WASO (primary) and latency to persistent sleep (LPS; secondary) to Days 1&2 (mean of two treatment nights assessed by polysomnography) in each period. Safety and tolerability were also assessed.</p> <p><b>Results:</b> Of 58 subjects included, 67% were female and median age was 69 years [range 65–85]). WASO and LPS were dose-dependently reduced from baseline to Days 1&2 following daridorexant administration (multiple comparison procedure-modeling, p<0.0001 and p=0.004, respectively); reductions were statistically significant for doses 10 mg and above compared with placebo (WASO: –32.0, –45.1, –61.4 min; LPS: –44.9, –43.8, –45.4 min; for 10, 25, and 50 mg, respectively, p≤0.025). Treatment-emergent adverse events were similar for daridorexant and placebo; the most frequent were fatigue, nasopharyngitis, gait disturbance, and headache (≤7% in any group).</p> <p><b>Conclusions:</b> Daridorexant was well tolerated. Dose-dependent improvements in WASO and LPS were statistically significant (dose range 10–50 mg) in elderly subjects with insomnia disorder. ClinicalTrials.gov (NCT02841709).</p> <p><b>Classification of Evidence:</b> This study provides Class III evidence that for elderly subjects with insomnia, daridorexant reduced wake after sleep onset time.</p>
ScienceDex guides
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.