Find research datasets worth reusing
Search datasets from major research repositories and use ShareScore to quickly assess how well each record supports discovery, access, and reuse.
2,009
datasets available to search
ShareScore release 0.9.0
Dataset results
2,009 results for “Disruption”
PRPF8-mediated dysregulation of hBrr2 helicase disrupts human spliceosome kinetics and 5'-splice-site selection causing tissue-specific defects
GEO Series GSE236702. Homo sapiens. 96 samples. Type: Expression profiling by high throughput sequencing.
BRB-seq analysis of PFOS-induced thyroid hormone system disrupted rats reveal organ-specific effects
GEO Series GSE196133. Rattus norvegicus. 192 samples. Type: Expression profiling by high throughput sequencing.
Ataxia-telangiectasia mutated (Atm) disruption sensitizes spatially-directed H3.3K27M/TP53 diffuse midline gliomas to radiation therapy
GEO Series GSE246584. Mus musculus. 4 samples. Type: Other.
Disruption of RNAPII transcription elongation links Oncogenic splicing factor mutations to replciation stress and targetable alterations in chromatin landscape [nascent RNAseq]
GEO Series GSE226000. Homo sapiens. 4 samples. Type: Expression profiling by high throughput sequencing.
Migration through a small pore disrupts inactive chromatin organisation in neutrophil-like cells [Hi-C]
GEO Series GSE115633. Homo sapiens. 9 samples. Type: Other.
Disrupting the CBP/ β-catenin Axis: A Path to Suppress Survivin and Induce Apoptosis in Melanoma
GEO Series GSE301849. Homo sapiens. 3 samples. Type: Expression profiling by high throughput sequencing.
SMARCA4-mutant lung cancer disrupts anti-tumor immunity and immunotherapy response in a STING pathway-dependent manner [H1975 and HCC44]
GEO Series GSE269618. Homo sapiens. 8 samples. Type: Expression profiling by high throughput sequencing.
Neonatal diabetes mutations disrupt a chromatin pioneering function that activates the human insulin gene
GEO Series GSE151405. Homo sapiens. 2 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
A BRCA1 coiled-coil domain variant disrupting PALB2 interaction predisposes to mammary tumors with a targetable defect in homologous recombination repair [CNV-seq]
GEO Series GSE182449. Mus musculus. 101 samples. Type: Other.
Integrated Systems Biology Identifies Disruptions in Mitochondrial Function and Metabolism as Key Contributors to HFpEF
GEO Series GSE301671. Rattus norvegicus. 18 samples. Type: Expression profiling by high throughput sequencing.
Natural regulatory mutations elevate fetal globin via disruption of BCL11A or ZBTB7A binding
GEO Series GSE103445. Homo sapiens. 16 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Intestinal Epithelial C/EBPβ Deficiency Impairs Colitis-Associated Tumorigenesis by Disrupting CXCL1 /CXCL2/CXCL5-CXCR2-Mediated Neutrophil Infiltration [RNA-seq ]
GEO Series GSE264497. Mus musculus. 15 samples. Type: Expression profiling by high throughput sequencing.
Dual Targeting of FLT3 and LSD1 Disrupts the MYC Super Enhancer Complex in Acute Myeloid Leukemia.
GEO Series GSE190785. Homo sapiens. 289 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.
Transcriptome analysis after disruption of nuclear F-actin in mouse embryos
GEO Series GSE126317. Mus musculus. 15 samples. Type: Expression profiling by high throughput sequencing.
SMARCA4-mutant lung cancer disrupts anti-tumor immunity and immunotherapy response in a STING pathway-dependent manner [H1792_RNA-seq]
GEO Series GSE269930. Homo sapiens. 4 samples. Type: Expression profiling by high throughput sequencing.
Broad-spectrum antibiotics disrupt homeostatic efferocytosis [scRNA-seq]
GEO Series GSE270512. Mus musculus. 1 samples. Type: Expression profiling by high throughput sequencing.
Limb reduction in an Esco2 cohesinopathy mouse model is mediated by p53-dependent apoptosis and vascular disruption [RNA-Seq]
GEO Series GSE230347. Mus musculus. 18 samples. Type: Expression profiling by high throughput sequencing.
A framework to identify functional interactors that contribute to disrupted early retinal development in Vsx2 mutant mice III
GEO Series GSE227055. Mus musculus. 12 samples. Type: Expression profiling by high throughput sequencing.
Zebrafish embryos exposed to the model hedgehog pathway inhibitor cyclopamine, as well as to the potential hedghog pathway disrupters SANT-2 and GANT-61.
GEO Series GSE29357. Danio rerio. 20 samples. Type: Expression profiling by array.
An atlas of single-base-resolution N6-methyl-adenine methylomes redefines RNA demethylase function as suppressors of disruptive RNA methylation
GEO Series GSE124509. Homo sapiens; synthetic construct. 86 samples. Type: Other.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.