Find research datasets worth reusing
Search datasets from major research repositories and use ShareScore to quickly assess how well each record supports discovery, access, and reuse.
800
datasets available to search
ShareScore release 0.9.0
Dataset results
800 results for “RNA methylation”
Characterizing Epigenetic Changes in Methylation Mutants (elp2-5 and met1-7) in Response to Spaceflight. [RNA-Seq]
Epigenetic changes in the DNA methylome are increasingly shown to play an integral role in regulating gene expression necessary for plants adaption to environmental stressors. Plants subjected to the novel environment of spaceflight onboard the International Space Station (ISS), show stress-related transcriptomic changes most notably associated with pathogen stress response. Here, we investigate how known terrestrial stress associated epigenetic modulations might play a role in spaceflight adaptation. To examine the role of 5mCyt in spaceflight adaptation, the APEX04-EPEX experiment conducted onboard the ISS evaluated the spaceflight altered genome wide methylation profiles of two methylation regulating gene mutants (methyltransferase 1 (met1-7) and elongator complex subunit 2 (elp2-5) that are involved in pathogen defense response, along with a wild type Col-0 control. MethylSeq and RNAseq analyses were performed on both spaceflight grown samples and ground grown controls. In addition, the epigenetics effects that may contribute to the differential gene expression patterns observed between leaf and root tissues were also investigated in an organ-specific manner.
Histone methylation regulator PTIP orchestrates inflammatory responses via modulating acetylation state of cis-regulatory elements [BMDM-RNA-seq]
GEO Series GSE163208. Mus musculus. 8 samples. Type: Expression profiling by high throughput sequencing.
SON controls mouse early embryonic development by regulating RNA splicing and histone methylation
GEO Series GSE273029. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
Inducible histone K-to-M mutations are dynamic tools to probe the physiological role of site-specific histone methylation in vitro and in vivo [RNA]
GEO Series GSE126826. Mus musculus. 18 samples. Type: Expression profiling by high throughput sequencing.
Methyl Gallate Alleviates Acute Ulcerative Colitis by Modu-lating Gut Microbiota and Inhibiting TLR4/NF-κB Pathway [RNA-seq]
GEO Series GSE216434. Mus musculus. 9 samples. Type: Expression profiling by high throughput sequencing.
H3K9 methylation fine-tunes coordination of transcription by regulating the conformational plasticity of chromosomal folding [RNA-Seq]
GEO Series GSE58535. Homo sapiens. 16 samples. Type: Expression profiling by high throughput sequencing.
Trans-differentiation takes place without reprogramming of developmental-specific DNA methylation, a key determinant of stable cell identity [RNA-seq]
GEO Series GSE252353. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
DOT1L-mediated CDK9 methylation is essential for DNA double-strand break repair [RNA-seq]
GEO Series GSE315014. Homo sapiens. 10 samples. Type: Expression profiling by high throughput sequencing.
Chromatin immunoprecipitation and RNA-seq analysis in purified quiescent yeast cells to identify the genomic RNA polymerase II and histone H3 methylation occupancy profiles and the quiescent cell tran
GEO Series GSE72650. Saccharomyces cerevisiae. 6 samples. Type: Expression profiling by high throughput sequencing.
The unique establishment of histone H3 lysine 4 mono-methylation pattern on the promoter regions in early embryo development [RNA-seq]
GEO Series GSE179939. Mus musculus. 12 samples. Type: Expression profiling by high throughput sequencing.
Optimization of NaIO4 Oxidation and Deep-sequencing Methodology for Detection of 3' End Methylation of Small RNAs in low-input RNA Samples
GEO Series GSE130106. Mus musculus. 12 samples. Type: Non-coding RNA profiling by high throughput sequencing.
RNA polymerase IV is essential for tomato embryo development through mediating non-CG methylation [RNA-Seq]
GEO Series GSE246016. Solanum lycopersicum. 8 samples. Type: Expression profiling by high throughput sequencing.
Dnmt1 binds and represses genomic retroelements via DNA methylation in mouse early embryos (RNA-seq)
GEO Series GSE111265. Mus musculus. 2 samples. Type: Expression profiling by high throughput sequencing.
Methylated RNA immunoprecipitation sequencing in the Kasumi-1 cell line treated with CoCl2 and echinomycin
GEO Series GSE200605. Homo sapiens. 6 samples. Type: Other.
Uncovering the role admixture in health disparities: Association of hepatocyte gene expression and DNA methylation to African Ancestry in African-Americans [RNA-seq]
GEO Series GSE222593. Homo sapiens. 355 samples. Type: Expression profiling by high throughput sequencing.
Evidence of DNA methylation in Aspergillus oryzae [RNA-seq]
GEO Series GSE130260. Aspergillus oryzae RIB40. 6 samples. Type: Expression profiling by high throughput sequencing.
Sex-Specific DNA Methylation and Gene Expression Changes in Mouse Placentas After Early Preimplantation Alcohol Exposure[RNA-Seq]
GEO Series GSE254846. Mus musculus. 16 samples. Type: Expression profiling by high throughput sequencing.
Extrachromosomal circular SUZ12 amplicon dictates retinoblastoma progression through reprogramming H3K27 methylation [RNA-seq]
GEO Series GSE235887. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
RNA polymerase IV is essential for tomato embryo development through mediating non-CG methylation [sRNA-seq]
GEO Series GSE246017. Solanum lycopersicum. 6 samples. Type: Non-coding RNA profiling by high throughput sequencing.
RNA m1A methylation regulates glycolysis of cancer cells through modulating ATP5D
GEO Series GSE195637. Homo sapiens. 12 samples. Type: Expression profiling by high throughput sequencing; Other.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.