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666
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ShareScore release 0.9.0
Dataset results
666 results for “Translocation”
Transcription-associated Loading and Translocation of Condensin II on Chromosome Arms in Embryonic Stem Cells (RNA)
GEO Series GSE30920. Mus musculus. 8 samples. Type: Expression profiling by array.
Topoisomerases I and II facilitate the translocation of condensin DC in C. elegans [HiC]
GEO Series GSE188849. Caenorhabditis elegans. 4 samples. Type: Other.
RNA sequencing of 13 T-cell acute lymphoblastic leukemia patients (5 TCRAD-MYC translocated T-ALL_8TAL1-LMO2 T-ALL)
GEO Series GSE106699. Homo sapiens. 13 samples. Type: Expression profiling by high throughput sequencing.
The prognostic value of the detection of microbial translocation in the blood of colorectal cancer patients
<p>Results of a retrospective analysis aiming to investigate whether microbial translocation occurs in colorectal cancer patients and to evaluate the usefulness of PCR for diagnosis of such translocation in the blood of these patients before treatment initiation. The secondary objective of the study was the correlation of the presence of previously investigated by our group toll-like and vitamin D receptor gene polymorphisms with the detection of microbial DNA fragments in the blood of colorectal cancer patients. </p> <p>The detection of microbial DNA fragments in CRC patients highlights the role of these microbes in cancer development, progression and patients’ survival. Clearly, this increased risk in colorectal patients should be taken into consideration by the clinicians when planning any surgical intervations or during chemotherapy</p>
Binding-mediated direct translocation of HIV-1 Tat-conjugated quantum dots in living cells
<p>Cell-penetrating peptides (CPPs) can translocate across cell membranes, and thus have great potential for the cellular delivery of macromolecular cargoes. However, the mechanism of this cellular uptake process is not yet fully understood. In this study, time-lapse light sheet optical microscopy was implemented to obtain a parallel visualization of the translocating dynamics of individual human immunodeficiency virus 1 (HIV-1) transactivator of transcription (Tat) peptide conjugated quantum dots in complex cellular terrains. Remarkable trajectory aggregates were observed on the cell surface, possibly caused by interaction between the Tat peptides and heparan sulfate groups on the plasma membrane. Spectral-embedding analysis of the trajectory aggregates revealed a manifold formed by isotropic diffusion and directed movement. Further stochastic analysis indicated that the Tat peptides may have remodeled the actin framework in the cytoplasm to reduce their interaction with local membrane environment. The membrane deformation induced by Tat-peptide attachment increased with the disruption of the actin framework, yielding higher interactions on the Tat-coated particle. Characteristic hot spots for interaction were detected on the membrane, suggesting that a funnel passage had formed for the Tat-coated particles. This finding offers valuable insight into the cellular delivery of nanoscale cargoes, suggesting an avenue for direct therapeutic delivery. </p>
Single DNA molecule translocation plots
<p>Firts results of translocations of a 24 kbp dsDNA long passing through a 50 nm nanocapillarity</p>
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.