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Dataset results
700 results for “Molecular identification”
Molecular identification of genes involved in testicular steroid synthesis and characterization of the response to gonadotropic stimulation in the Senegalese sole (Solea senegalensis)
GEO Series GSE25733. Solea senegalensis. 2 samples. Type: Expression profiling by array.
Clonal Analysis for Identification of Molecular Pathways with Potential Therapeutic Implications in of Rare Gastrointestinal and Endocrine Cancers
GEO Series GSE34063. Homo sapiens. 17 samples. Type: Genome variation profiling by genome tiling array.
Identification of molecular mechanisms related with fatness in pig at transcriptome and miRNAome level
GEO Series GSE122816. Sus scrofa. 22 samples. Type: Expression profiling by high throughput sequencing.
Calcineurin inhibitor-induced renal side effects – Identification of underlying molecular mechanism via transcriptional analysis on large-scale isolated renal tubules
GEO Series GSE169721. Mus musculus. 8 samples. Type: Expression profiling by high throughput sequencing.
Identification of novel molecular subgroups in esophageal adenocarcinoma to predict response to neo-adjuvant therapies
GEO Series GSE207526. Homo sapiens. 120 samples. Type: Expression profiling by high throughput sequencing.
Identification of clinical and molecular features for recurrent serous borderline ovarian tumor
GEO Series GSE190526. Homo sapiens. 21 samples. Type: Expression profiling by high throughput sequencing.
Molecular identification of Bactrocera passiflorae (Diptera: Tephritidae): challenge and solution for DNA barcoding
<p>Fruit flies cause significant damage to crop and fruit production worldwide. Therefore it is essential to identify these organisms to species level, however, immature stages are often impossible to be identified morphologically, thus the application of DNA barcoding has greatly assisted in species identification. Nuclear, mitochondrial pseudo-COI (NUMT) can be co-amplified with mitochondrial DNA when using generic primers and therefore impair the efficacy of DNA barcoding. This study detected two types of NUMTs from<em> B. passiflorae, </em>one of them is novel. Therefore the new finding will assist future species identification by avoiding misidentification using ambiguous NUMT sequences. In addition, this study have developed primers to target the COI gene of <em>B. passiflorae</em>, not the NUMT copies. The newly designed primers have demonstrated its efficiency in amplifying the Mt-COI of <em>B. passiflorae </em>and can be used in routine diagnostics.</p>
Fig. 1 in Serratene triterpenoids from Lycopodium cernuum L. as α-glucosidase inhibitors: Identification, structure-activity relationship and molecular docking studies
Fig. 1. Compounds (1–18) isolated from L. cernuum.
Figure 1 in Molecular identification of eriophyoid mites in Thrace using the 28S and COI genes
Figure 1. Map of the study area showing the sampling fields.
Systematic identification of molecular pathways driving GBM invasion
GEO Series GSE87535. Homo sapiens. 4 samples. Type: Expression profiling by high throughput sequencing.
Identification of distinct molecular signatures in BRAF V600E and BRAF wt cutaneous melanomas
GEO Series GSE22838. Homo sapiens. 18 samples. Type: Expression profiling by array.
Expression data from bovine oocyte; Identification of molecular markers for oocyte competence in bovine cummulus cells
GEO Series GSE65269. Bos taurus. 6 samples. Type: Expression profiling by array.
Identification of genes and molecular pathways associated with anti-miR-182 treatment.
GEO Series GSE24824. Homo sapiens. 8 samples. Type: Expression profiling by array.
Identification of molecular factors explaining decreased hypocotyl growth at low temperature
GEO Series GSE18449. Sinorhizobium meliloti; Medicago sativa; Medicago truncatula. 24 samples. Type: Expression profiling by array.
Identification of Potential Multi-Target Directed Ligands Through Virtual Screening and Molecular Dynamics Simulation Approach for the Treatment of Alzheimer's Disease
<p>Alzheimer’s disease (AD) is a multifactorial neurological disorder characterized by memory loss and cognitive impairment. The currently available single-targeting drugs have miserably failed in the treatment of AD and multi-target directed ligands (MTDLs) are being explored as an alternative strategy. Cholinesterase and monoamine oxidase enzymes are reported to play crucial role in the pathology of AD and multipotent ligands targeting these two enzymes simultaneously, are under various phases of design and development. Recent studies have revealed that computational approaches are robust and trusted tools for the identification of novel therapeutics. The current research work is focused on the development of potential multitarget directed ligands that simultaneously inhibit acetylcholinesterase (AChE) and monoamine oxidase B (MAO-B) enzymes employing structure-based virtual screening (SBDD) approach. The ASINEX database was screened after applying pan assay interference and drug likeness filter to identify novel molecules using three docking precision criteria Highthroughput virtual screening (HTVS), Standard Precision (SP), and extra precision (XP). Additionally, binding free energy calculations, ADME and molecular dynamic simulations were also employed to get structural insights into mechanism of protein-ligand binding and pharmacokinetic properties. Three lead molecules viz. AOP19078710, BAS00314308 and BDD26909696 were successfully identified which displayed binding score of -10.565, -10.543 & -8.066 kcal/mol against AChE and -11.019, -12.357 & -10.068 kcal/mol against MAO-B, better score as compared to the standard inhibitors. In near future, these molecules will be synthesized and evaluated through in vitro and in vivo assays for their inhibition potential against AChE and MAO-B enzymes.</p>
Data for the manuscript "Identification and structural studies of the crucial RNAi target of SARS-CoV-2 through molecular dynamics simulations"
<p>Simulation datasets for manuscript titled "<strong>Identification and structural studies of the crucial RNAi target of SARS-CoV-2 through molecular dynamics simulations"</strong></p>
Identification of molecular mechanisms involved in pathogenesis of MALT lymphoma from small sample size
GEO Series GSE16024. Homo sapiens. 62 samples. Type: Expression profiling by array.
Identification of molecular pathways involved in oxaliplatin-associated sinusoidal dilatation
GEO Series GSE32384. Homo sapiens. 24 samples. Type: Expression profiling by array.
Identification of consensus molecular subtypes in muscle-invasive bladder cancer: A comparison of two sequencing methods and gene sets using FFPE specimens
GEO Series GSE225376. Homo sapiens. 30 samples. Type: Expression profiling by high throughput sequencing.
Identification of Potential DNA Gyrase Inhibitors: Virtual Screening, Extra-Precision Docking and Molecular Dynamics Simulation Study
<p>These are the data generated during the research. All these data will be linked to the entitled work, which will be published as a research article.</p>
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.