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1,198
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Dataset results
1,198 results for “Vaccination and immunization”
UCPVax, a CD4 helper peptide vaccine induces polyfunctional Th1 cells, antibody response and epitope spreading to improve antitumor immunity [TCR-seq]
GEO Series GSE271545. Homo sapiens. 10 samples. Type: Other.
Chromosomal instability can favor macrophage-mediated immune response and induce a broad, vaccination-like anti-tumor IgG response [RNA-Seq]
GEO Series GSE261556. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
Distinct baseline immune characteristics associated with responses to conjugated and unconjugated pneumococcal polysaccharide vaccines in older adults [scRNA-seq]
GEO Series GSE247277. Homo sapiens. 11 samples. Type: Expression profiling by high throughput sequencing.
Immune transcriptome in adult-onset Still’s disease with mild flare following administration of mRNA vaccine BNT162b2
GEO Series GSE198549. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
Effect of Antigen, Type I IFN and STING Signaling on CD8 T Cell Immunity With Adenoviral Vaccines
GEO Series GSE64548. Mus musculus. 207 samples. Type: Expression profiling by array.
mRNA COVID-19 vaccine elicits potent adaptive immune response without the acute inflammation of SARS-CoV-2 infection [CV9]
GEO Series GSE247909. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing; Other.
Epigenetic aging in immune response to HBV vaccine in B cells isolated from health care workers
GEO Series GSE273657. Homo sapiens. 71 samples. Type: Methylation profiling by genome tiling array.
Non-protective immune imprint underlies failure of S. aureus IsdB vaccine
GEO Series GSE193543. Mus musculus. 3 samples. Type: Expression profiling by high throughput sequencing.
Differential Immune Transcriptomic Profiles between Vaccinated and Resolved HCV Reinfected Subjects
GEO Series GSE206397. Homo sapiens. 27 samples. Type: Expression profiling by high throughput sequencing.
Impact of two and three dose COVID-19 vaccination schedule on transcriptional, humoral and T cell immune response in previously heavily treated, single agent treated and naïve CLL patients
GEO Series GSE201642. Homo sapiens. 48 samples. Type: Expression profiling by high throughput sequencing.
Mitochondrial Hyperactivity and Reactive Oxygen Species Drive Innate Immunity to the Yellow Fever Virus-17D Live-Attenuated Vaccine
GEO Series GSE293880. Homo sapiens. 36 samples. Type: Expression profiling by high throughput sequencing.
mRNA COVID-19 vaccine elicits potent adaptive immune response without the acute inflammation of SARS-CoV-2 infection [HC]
GEO Series GSE247916. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing; Other.
An mRNA vaccine induces antimycobacterial immunity by activating DNA damage repair and autophagy
GEO Series GSE269547. Danio rerio. 6 samples. Type: Expression profiling by high throughput sequencing.
Data for "Integrating population and single-cell variations in vaccine responses identifies a naturally adjuvanted human immune setpoint"
<p>Data associated with the manuscript:</p> <p>"Integrating population and single-cell variations in vaccine responses identifies a naturally adjuvanted human immune setpoint"</p> <p>Please see code/documentation associated with these data at the links below: </p> <p>Analysis code + documentation: <a href="https://niaid.github.io/fsc/">https://niaid.github.io/fsc/</a></p> <p>Analysis code Github repository: <a href="https://github.com/niaid/fsc">https://github.com/niaid/fsc</a></p> <p>In the downloaded directory the subdirectory 'data' contains data files including: </p> <p><strong>flu_vacc_CITEseq_Seurat4.rds </strong>is CITE-seq data as a Seurat version 4 object for R. </p> <p><strong>flu_vacc_CITEseq_combinedassay.h5ad</strong> is CITE-seq data as a .h5ad object for python. </p>
SARS-CoV-2-specific cellular and humoral immunity after bivalent BA.4/5 COVID-19-vaccination in previously infected and non-infected individuals
<p>Data accompanying manuscript by Urschel et al. </p>
Heterologous immunization with inactivated vaccine followed by mRNA booster elicits strong humoral and cellular immune responses against the SARS-CoV-2 Omicron variant
<p>The recent emergence of the Omicron variant has raised concerns on vaccine efficacy and the urgent need to study more efficient vaccination strategies. Here we evaluated the effect of an mRNA vaccine booster on immunogenicity in individuals vaccinated with two doses of inactivated vaccine. We observed that an mRNA vaccine booster significantly increased the plasma level of specific antibodies that bind to the receptor-binding domain (RBD) or the spike (S) ectodomain (S1+S2) of both the G614 and the Omicron variants, compared to two doses of homologous inactivated vaccine. The level of RBD- and S-specific IgG antibodies and virus neutralization titers against variants of concern in the heterologous vaccination group were similar to that in individuals receiving three doses of homologous mRNA vaccine or a boost of mRNA vaccine after infection, but markedly higher than that in individuals receiving three doses of a homologous inactivated vaccine. Moreover, this heterologous vaccination regime significantly enhanced the RBD-specific memory B cell response and S1-specific T cell response compared to two or three doses of homologous inactivated vaccine. Our study demonstrates that an mRNA vaccine booster in individuals vaccinated with inactivated vaccines can be highly beneficial, as it markedly increases the humoral and cellular immune responses against the virus, including the Omicron variant</p>
Adaptive immune responses to Omicron BA.4/BA.5-containing bivalent mRNA booster vaccination
<p>This repository contains the immunoSEQ T-cell receptor (TCR) and B-cell receptor (BCR) repertoire data used in the manuscript titled "Adaptive immune responses to Omicron BA.4/BA.5-containing bivalent mRNA booster vaccination". This data set is composed of the TCR/BCR repertoire clonotype sequences and abundances derived from human peripheral blood mononuclear cell (PBMC) samples sorted for CD4, CD8 and CD19 before and after bivalent COVID mRNA booster vaccination. In total, 84 TCR samples (CD4+/CD8+ T cell populations at pre-/post-vaccination from 21 subjects) and 42 BCR samples (CD19+ populations at at pre-/post-vaccination from 21 subjects) are present in the data set.</p> <ul> <li><em><strong>Delmonte_TCR_data_84samples.rds</strong></em><br>R object with the amino acid and nucleotide sequences, VDJ gene calls, and abundances of the TCR clonotypes.</li> <li><strong><em>Delmonte_BCR_data_42samples.rds </em></strong> <br>R object with the amino acid and nucleotide sequences, VDJ gene calls, and abundances of the BCR clonotypes.</li> <li><em><strong>Delmonte_TCR_data_compact_84samples.rds</strong></em><br>R object with the amino acid sequences, VDJ gene calls, and abundances of the TCR clonotypes.</li> <li><em><strong>Delmonte_BCR_data_compact_42samples.rds </strong></em><br>R object with the amino acid sequences, VDJ gene calls, and abundances of the BCR clonotypes.</li> <li><em><strong>sampleExport_TCR.zip</strong></em><br>Compressed folder that includes the individual sample level TCR repertoire files in .tsv format.</li> <li><em><strong>sampleExport_BCR.zip</strong></em><br>Compressed folder that includes the individual sample level BCR repertoire files in .tsv format.</li> </ul> <p><br><em>Funding statement: This work was supported by the Division of Intramural Research Programs of the National Institute of Allergy and Infectious Diseases and of the National Institute of Dental and Craniofacial Research, National Institutes of Health (grant AI001270).</em><br><br></p> <p> </p>
Evaluation of Immune Response Against the Strain of Neisseria Meningitidis B: 14, P1-7, 16 in Patients Having to be Vaccinated MenBVac® (Extension EFFIVAC)
ClinicalTrials.gov study NCT01621945. IPD Sharing: Not stated. Countries: 1. Publications: 0.
An Immunity Persistence Study of Live Attenuated Varicella Vaccine
ClinicalTrials.gov study NCT05095701. IPD Sharing: Not stated. Countries: 1. Publications: 0.
A Study on the Safety, Reactogenicity, and Immune Response to the GVGH iNTS-GMMA Vaccine Against Invasive Nontyphoidal Salmonella in Adults, Children, and Infants
ClinicalTrials.gov study NCT06213506. IPD Sharing: YES. Countries: 1. Publications: 0.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.