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Supplemental material for the paper "Genotype-phenotype correlation, clinical presentation, and feminizing surgery in children with congenital adrenal hyperplasia - a nationwide study"

This dataset provides documentation for the translation between historical nomenclature for variants in the CYP21A2 gene to the Human genome variation society nomenclature.  Furthermore, it provides data on all Danish CYP21A2 variants included in the study and the translation into genotype groups: Null, A, B, C, and D.

Datasets for 176Lu+ clock comparison at the 10E-18 level via correlation spectroscopy

Datasets and figure data for "176Lu+ clock comparison at the 10E-18 level via correlation spectroscopy"

Spreadsheet working analysis (uncleaned): correlation of global warming with Gross World Product (PPP) for 1850–2021

This workbook has not been peer-reviewed. Do not cite. Use with caution. For analysis charts see the sheet entitled CHARTS GDP totals and CO2. Source data: Gross world product data from: Bolt, J., van Zanden, J.L., 2020. Maddison Project Database 2020 [WWW Document]. Univ. Gron. URL https://www.rug.nl/ggdc/historicaldevelopment/maddison/releases/maddison-project-database-2020 (accessed 11.22.22). Global CO2 data from: CDIAC, 2017. Global, Regional, and National Fossil-Fuel CO2 Emissions. Carbon Dioxide Information Analysis Center. Friedlingstein, P., O’Sullivan, M., Jones, M.W., Andrew, R.M., Gregor, L., Hauck, J., Le Quéré, C., Luijkx, I.T., Olsen, A., Peters, G.P., Peters, W., Pongratz, J., Schwingshackl, C., Sitch, S., Canadell, J.G., Ciais, P., Jackson, R.B., Alin, S.R., Alkama, R., Arneth, A., Arora, V.K., Bates, N.R., Becker, M., Bellouin, N., Bittig, H.C., Bopp, L., Chevallier, F., Chini, L.P., Cronin, M., Evans, W., Falk, S., Feely, R.A., Gasser, T., Gehlen, M., Gkritzalis, T., Gloege, L., Grassi, G., Gruber, N., Gürses, Ö., Harris, I., Hefner, M., Houghton, R.A., Hurtt, G.C., Iida, Y., Ilyina, T., Jain, A.K., Jersild, A., Kadono, K., Kato, E., Kennedy, D., Klein Goldewijk, K., Knauer, J., Korsbakken, J.I., Landschützer, P., Lefèvre, N., Lindsay, K., Liu, J., Liu, Z., Marland, G., Mayot, N., McGrath, M.J., Metzl, N., Monacci, N.M., Munro, D.R., Nakaoka, S.-I., Niwa, Y., O’Brien, K., Ono, T., Palmer, P.I., Pan, N., Pierrot, D., Pocock, K., Poulter, B., Resplandy, L., Robertson, E., Rödenbeck, C., Rodriguez, C., Rosan, T.M., Schwinger, J., Séférian, R., Shutler, J.D., Skjelvan, I., Steinhoff, T., Sun, Q., Sutton, A.J., Sweeney, C., Takao, S., Tanhua, T., Tans, P.P., Tian, X., Tian, H., Tilbrook, B., Tsujino, H., Tubiello, F., van der Werf, G.R., Walker, A.P., Wanninkhof, R., Whitehead, C., Willstrand Wranne, A., Wright, R., Yuan, W., Yue, C., Yue, X., Zaehle, S., Zeng, J., Zheng, B., 2022. Global Carbon Budget 2022. Earth Syst. Sci. Data 14, 4811–4900. https://doi.org/10.5194/essd-14-4811-2022

Ultra-Accurate Correlation Between Precursor and Fragment Ions in Two-lDimensional Mass Spectrometry: Acetylated vs. Trimethylated Histone Peptides

Two-dimensional mass spectrometry (2D MS) is a method for tandem mass spectrometry in which precursor and fragment ions are correlated by manipulating ion radii rather than by ion isolation. A 2D mass spectrum contains the fragmentation patterns of all analytes in a sample, acquired in parallel. We report ultrahigh-resolution narrowband 2D mass spectra of a mixture of two histone peptides with the same sequence, one of which carries an acetylation and the other a trimethylation (m/z 0.006 difference). We reduced the distance between data points in the precursor ion dimension and compared the accuracy of the precursor-fragment correlation with the resolving power. We manage to perform label-free quantification on the histone peptide mixture and show that precursor and fragment ions can be accurately correlated even though the precursor ions are not resolved. Finally, we show that increasing the resolution of a 2D mass spectrum in the precursor ion dimension too far can lead to a decline in the signal-to-noise ratio.

Correlative study of liquid in human bone by 3D neutron microscopy and lab-based X-ray µCT

X-ray (xray_data.tiff) and neutron microscopy (neutron_data.tiff) of the same piece of human cortical bone. Neutron data were collected at the neutron microscope at SINQ, PSI, Switzerland while the x-ray data were collected in house at an VERSA 620 X-ray microscope.  The voxel size is in both case 2.7 µm

opencc-by-4.0Nov 2022View details →

Correlation of viral loads in disease transmission could affect early estimates of the reproduction number

This dataset accompanies the an article titled, 'Correlation of viral loads in disease transmission could affect early estimates of the reproduction number', by T. Harris et al. which can be found at https://arxiv.org/abs/2211.08673. Abstract: Early estimates of the transmission properties of a newly emerged pathogen are critical to an effective public health response, and are often based on limited outbreak data. Here, we use simulations to investigate how correlations between the viral load of cases in transmission chains can affect estimates of these fundamental transmission properties. Our computational model simulates a disease transmission mechanism in which the viral load of the infector at the time of transmission influences the infectiousness of the infectee. These correlations in transmission pairs produce a population-level convergence process during which the distributions of initial viral loads in each subsequent generation converge to a steady state. We find that outbreaks arising from index cases with low initial viral loads give rise to early estimates of transmission properties that could be misleading. These findings demonstrate the potential for transmission mechanisms to affect estimates of the transmission properties of newly emerged viruses in ways that could be operationally significant to a public health response.   Contents of this dataset include:  <ul> <li>Model code - including experiments (python3)</li> <li>Estimation code (R)</li> <li>Code used for figure production (python3 & R)</li> <li>Raw data produced from Experiments 1-3 and presented in the text (.csv & .Rdata)</li> </ul> See 'README.md' in main upload folder for more information

Коэффициенты корреляции повторяемости блокирования между секторами для северного и южного режимов для двух периодов. Blocking frequency correlation coefficients between sectors for northern and southern regimes for two periods.

Представлены коэффициенты корреляции (выше порога 0.4) повторяемости блокирования между секторами для северного (NM) и южного режимов (SM) для ноября (nov), декабря (dec), января (jan) и февраля (feb) . Секторы показаны в https://doi.org/10.5281/zenodo.7489504 Correlation coefficients (above a threshold of 0.4) of blocking frequency between sectors for northern (NM) and southern (SM) modes for November (nov), December (dec), January (jan) and February (feb) are presented. Sectors are shown at https://doi.org/10.5281/zenodo.7489504

Tracing the future of epidemics: Coincident niche distribution of host animals and disease incidence revealed climate-correlated risk shifts of main zoonotic diseases in China

This dataset contains host occurrence data from NACRC database and disease incidence data for the paper "Tracing the future of epidemics: Coincident niche distribution of host animals and disease incidence revealed climate-correlated risk shifts of main zoonotic diseases in China".

opencc-by-4.0Aug 2022View details →

Unconventional correlated insulator in CrOCl-interfaced Bernal bilayer graphene

Gap opening in a wide-enough doping range, whilst keeping high conductance outside this gapped state, has remained a grand challenge in graphene since decades. Here, we show a unique heterostructure of Bernal-stacked bilayer graphene (BLG) atop few-layered CrOCl, which enables a surface state in CrOCl under vertical electric fields, and it promotes electron-electron(e-e) interactions in BLG via Coulomb long ranged coupling. Consequently, at the charge neutral, a crossover from single particle insulating behavior to an unconventional correlated insulator is seen, below a critical temperature. The over1 GΩ insulating ground state exists in a widely accessible gate range,  and can be switched into a metallic state with an on/off ratio up to 107, by applying an in-plane electric field, heating, or by gating. A logic inverter using such correlated insulator is demonstrated, despite that it works still at low temperature. Our findings of the correlated insulating phase in CrOCl/BLG heterosystem paves the way for future engineering of exotic quantum electronic states in the paradigm of interfacial charge coupling.

Height covariance correlation function in Contact Process

Data of the correlation function, namely, the height covariance c1(r,t) for 1, 2 and 3 dimensions.  It has been measured for the interface representation of a contact process system at its critical point. See <a href="https://arxiv.org/abs/2304.10883">arXiv:2304.10883</a> for more details. Each file contain two headers starting with #. The columns show, in order, the time, the coordinate r, the value of c1(r,t), the error estimate by the jackknife procedure and the numbers of files used. All the columns are separated by space. Data for one-dimensional system in: c1JK-1D-L8192-t4000000-f2000.dat Data for two-dimensional system in: c1JK-2D-L512-t200000-f498.dat Data for three-dimensional system in: c1JK-3D-L128-t40000-f20.dat The datasets have been produced and employed in the context of a scientific work currently published in <a href="https://arxiv.org/abs/2304.10883">arXiv:2304.10883</a>.

opencc-by-4.0Apr 2023View details →

Dataset: Scatter of mechanical properties of 2D biaxial and triaxial braided reinforced composites and their correlation with visual features

The data represents tensile tests of 2D braided biaxial and triaxial composite laminates. Braids were produced on a Herzog radial braiding machine RF 1-176-100 with carbon fiber yarns (Toho Tenax F13 HTS40 12K 800 tex). Test laminates are infused with a VARI process with the 2-component epoxy resin system Hexion RIM235/RIMH237. The infusion is performed at vacuum pressure leves of 20-30 mbar and the resin is cured at room temperature for 24 hours at a pressure level of 250 mbar. A subsequent post-cure step maximizes matrix properties at 70°C for 10 hours. The braid setups have been chosen to achieve four different braids with a fiber angle of 45° on braid mandrels with a diameter of 120 mm, two biaxial ones and two triaxial ones. By using different sizes of braiding ring diameters and yarn forces, homogeneous and inhomogeneous fiber architectures are generated. Braiding setups 1 (biaxial) and 2 (triaxial)  with 130 mm braiding ring diameter and 350 g yarn force result in braids with homogeneous fiber architecture. 3 (biaxial, 400 mm braiding ring, 600 g yarn force) and 4 (triaxial, 250 mm braiding ring, 600 g yarn force) in braids with inhomogeneous scattering of visual characteristics. Single layers are braided on mandrels with a length of 1500 mm and laminates with 6 layers of biaxial and 4 layers of triaxial braids are subsequently infused. Tensile tests are performed on a Schenck-Trebel RM250 universal testing machine according to AITM 1-0007. For each specimen, the individual fiber orientation in each layer is measured prior to infusion by image analysis performed on scans of the braided layers. The results show a strong dependence of the individual fiber orientation of single test specimens on their mechanical properties in case of the presented tensile tests

opencc-zeroApr 2023View details →

Correlates of early reproduction and apparent fitness consequences in male Soay sheep

Life history trade-offs are ubiquitous across species and place constraints on the timing of life history events, including the optimal age at first reproduction. However, studies on lifetime breeding success of male mammals are rare due to sex-biased dispersal and the requirement for genetic paternity inferences. We studied the correlates and apparent fitness consequences of early-life reproduction among males in a free-living population of Soay sheep (Ovis aries) on St Kilda, Scotland. We investigated the factors associated with early breeding success and the apparent consequences of early success for survival and future reproduction. We used genetic paternity inferences, population data and individual morphology measurements collected over 30 years. We found that individuals born in years with low-density population size had the highest early-life breeding success, and singletons were more likely to be successful than twins. Individuals that bred successfully at seven months were more likely to survive their first winter. For individuals that survived their first winter, early breeding success was not associated with later breeding success. Since individual heterogeneity affects breeding success, we believe that variation in individual quality masks costs of early reproduction in this population. Our findings provide no evidence for selection for delayed age at reproduction in male Soay sheep.

opencc-zeroApr 2023View details →

Data from: Neural correlates of multisensory enhancement in audiovisual narrative speech perception: a fMRI investigation

This fMRI study investigated the effect of seeing articulatory movements of a speaker while listening to a naturalistic narrative stimulus. It had the goal to identify regions of the language network showing multisensory enhancement under synchronous audiovisual conditions. We expected this enhancement to emerge in regions known to underlie the integration of auditory and visual information such as the posterior superior temporal gyrus as well as parts of the broader language network, including the semantic system. To this end we presented 53 participants with a continuous narration of a story in auditory alone, visual alone, and both synchronous and asynchronous audiovisual speech conditions while recording brain activity using BOLD fMRI. We found multisensory enhancement in an extensive network of regions underlying multisensory integration and parts of the semantic network as well as extralinguistic regions not usually associated with multisensory integration, namely the primary visual cortex and the bilateral amygdala. Analysis also revealed involvement of thalamic brain regions along the visual and auditory pathways more commonly associated with early sensory processing. We conclude that under natural listening conditions, multisensory enhancement not only involves sites of multisensory integration but many regions of the wider semantic network and includes regions associated with extralinguistic sensory, perceptual and cognitive processing.

opencc-zeroMay 2023View details →

Data from: A correlation between seasonally changing photoperiod, whole body lipid, and condition factor in juvenile spring Chinook Salmon (Oncorhynchus tshawytscha)

The regulation of lipid stores is a central process for the physiology and ecology of fishes. Seasonal variation in lipid stores has been directly linked to survival of fishes across periods of food deprivation. We assessed whether a seasonally changing photoperiod was correlated to seasonal changes in energetic status to help better understand these important processes. Groups of first-feeding Chinook salmon fry were introduced to a seasonal photoperiod cycle, but the point of entrance into the seasonal cycle varied from near the winter solstice (December), to either side of the spring equinox (February & May). Temperature and feeding rate were similar for all treatments. Subsequently, condition factor and whole-body lipid content were assessed through a seasonal progression. Throughout most of the experiment, length and weight did not differ between the different photoperiod treatments, however whole body lipid and Fulton's condition factor did. Furthermore, changes in both whole body lipid and Fulton's condition factor in all treatment groups followed a similar seasonal pattern that was inversely related to day length (highest K and lipid levels found during days with the least light). These results suggest that regardless of age or size, there is a correlation between seasonal changes in photoperiod and changes in body composition in juvenile Chinook salmonids.

opencc-zeroMay 2023View details →

Correlation between body size and longevity: new analysis and data covering six taxonomic classes of vertebrates

Large bodied species are known to live longer than small bodied species. However, it is less clear whether the positive correlation varies across taxa. In this short communication, we combine data entries from literature and databases on body mass and maximum life span for 3722 species covering taxonomic Classes Chondrichthyes, Teleostei, Amphibia, Reptilia, Aves, and Mammalia. We then analyze the log(maximum life span) – log(body mass) relationship using generalized linear model with nested random intercepts and slopes for Class/Order/Family. Our analyses generally demonstrate the positive longevity – body mass relationship but also reveal that slopes and intercepts differ slightly among all Classes except Reptilia and Amphibia. Highest slopes can be found in Classes Aves and Chondrichthyes. Differences between the smallest and largest Family-level slopes was more than threefold. While these preliminary analyses provide a brief overview of body size – longevity relationships across taxa, the dataset collated in the present study could serve as a start point for in-depth phylogenetic analyses to uncover complex pathways through which body size and its correlates might have evolved.

opencc-zeroMay 2023View details →

Correlations between dominant vegetation type and composition and diversity of soil bacterial communities in a subtropical forest

Single and mixed vegetation types have significant effects on soil parameters and the composition and diversity of soil bacterial communities. To understand the influence of different vegetation types on the structure of soil bacterial community across soil depth in a subtropical forest, we assessed the relative abundance of edaphic bacterial community and soil parameters, including pH, cation exchange capacity (CEC), and dissolved organic carbon (DOC) in Daiyun Mountain Nature Reserve in Fujian Province, southeastern China. The study area constitutes pine coniferous forest (CF) of pinus taiwanensis, broad-leaved forest (BF) of castanopsis fabri, and a mixed forest comprising CF and BF (MF). Quantitative PCR and Illumina sequencing of 16S rDNA were used to analyze the abundance, diversity, and composition of soil bacteria. The results showed that the pH, CEC and diversity of tree species are all associated with the composition of the bacterial community in the soil. It was found that CEC, soluble organic nitrogen (DON) and pH largely affected the structure of soil bacterial community in A horizon, whereas CEC, moisture content (MC) and organic phosphorus (OP) affected the structure of soil bacterial community in B horizon. We found that the dominant taxa in the CF and BF were Proteobacteria and Acidobacteria, respectively. The results of both mental and random forest (RF) analyses displayed groups according to vegetation types, indicating that the bacterial communities in the research site were significantly influenced by vegetation types in subtropical forests. The study highlights the ecological effects of forest management and elucidates the differences in the functional structure of soil bacterial communities under different vegetation types and soil depths.

Embodiment of virtual feet correlates with motor performance in a target-stepping task: A pilot study

Dataset for the human factors pilot experiment of "Embodiment of virtual feet correlates with motor performance in a target-stepping task: A pilot study"

Investigating the fast spectral diffusion of a quantum emitter in hBN using resonant excitation and photon correlations

Data from the article "Investigating the fast spectral diffusion of a quantum emitter in hBN using resonant excitation and photon correlations" (<a href="https://journals.aps.org/prb/abstract/10.1103/PhysRevB.107.195304">Phys. Rev. B 107, 195304 (2023)</a> – [<a href="https://arxiv.org/abs/2303.05315">arXiv</a>])

Figure S1. Spearman correlation matrix representing the relationships between phytoestrogens and biofluids.

(A) Daidzein, (B) Genistein, (C) the sum of both phytoestrogens, (D) follicular fluid, (E) urine on the day of vaginal oocyte retrieval. Blue represents a positive correlation, while red represents a negative correlation. Color intensity is proportional to the correlation strength. Strikethrough values represent non-significant associations (p>0.05).

Figure S2. Spearman correlation matrix representing the relationships between the essential trace elements within each biological matrix

Blue represents a positive correlation, while red represents a negative correlation. Color intensity is proportional to the correlation strength. Strikethrough values represent insignificant/negligible associations (p>0.05). Cr, chromium; Cu, copper; Fe, iron; Li, lithium; Mn, manganese; Mo, molybdenum; Se, selenium; Zn, zinc