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2,009
datasets available to search
ShareScore release 0.9.0
Dataset results
2,009 results for “Disruption”
Inherited disorders of cobalamin metabolism disrupt nucleocytoplasmic transport of mRNA through impaired methylation/phosphorylation of HuR
GEO Series GSE103417. Mus musculus. 24 samples. Type: Expression profiling by array.
A TDP-43 acetylation-mimic mutation that disrupts RNA-binding drives FTLD-like neurodegeneration in a mouse model of sporadic TDP-43 proteinopathy
GEO Series GSE216294. Mus musculus. 20 samples. Type: Expression profiling by high throughput sequencing.
SMARCA4 ATPase mutations disrupt direct eviction of PRC1 from chromatin
GEO Series GSE88968. Mus musculus. 41 samples. Type: Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by high throughput sequencing.
ESRP1 mutations cause hearing loss due to defects in alternative splicing that disrupt cochlear development
GEO Series GSE90821. Mus musculus. 12 samples. Type: Expression profiling by high throughput sequencing.
Flame retardant tetrabromobisphenol A (TBBPA) disrupts histone acetylation and zygotic transcription during zebrafish embryogenesis
GEO Series GSE262783. Danio rerio. 24 samples. Type: Expression profiling by high throughput sequencing.
The early T4 protein, MotB, compacts host DNA and disrupts H-NS dependent repression.
GEO Series GSE152170. Escherichia coli BL21(DE3). 6 samples. Type: Expression profiling by high throughput sequencing.
Transcriptional heterogeneity overcomes super-enhancer disrupting drug combinations in multiple myeloma [ATAC-seq]
GEO Series GSE243978. Homo sapiens. 8 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
TIRAP drives myelosuppression through an Ifnγ-Hmgb1 axis that disrupts the endothelial niche.
GEO Series GSE172147. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
NR2E3 loss disrupts photoreceptor cell maturation and fate in human organoid models of retinal development
GEO Series GSE236197. Homo sapiens. 29 samples. Type: Expression profiling by high throughput sequencing; Other.
N'-(1-phenylethylidene)-benzohydrazide cytotoxicity is LSD1 independent and linked to Fe-S cluster disruption in Ewing sarcoma
GEO Series GSE286100. Homo sapiens. 15 samples. Type: Expression profiling by high throughput sequencing.
SETBP1 variants outside the degron disrupt DNA-binding, transcription and neuronal differentiation capacity to cause a heterogeneous neurodevelopmental disorder [induced neurons]
GEO Series GSE301239. Homo sapiens. 51 samples. Type: Expression profiling by high throughput sequencing.
Scn2a deletion disrupts oligodendroglia function: Implication for myelination, neural circuitry, and auditory hypersensitivity in ASD.
GEO Series GSE252185. Mus musculus. 1 samples. Type: Expression profiling by high throughput sequencing.
Human naïve-like T follicular regulatory cells are primed for differentiation into mature Tfr and disrupted during severe infections. (treatment with TPC or IL2)
GEO Series GSE287877. Homo sapiens. 12 samples. Type: Expression profiling by high throughput sequencing.
Disrupted PGR-B and ESR1 signaling underlies defective decidualization linked to severe preeclampsia
GEO Series GSE172381. Homo sapiens. 40 samples. Type: Expression profiling by high throughput sequencing.
Single-embryo RNA-seq analysis in LAD disrupted 2-cell embryos.
GEO Series GSE278720. Mus musculus. 87 samples. Type: Expression profiling by high throughput sequencing.
Disruption of miRNA Sequence by TALENs and CRISPR/Cas9 Induces Varied Length of miRNA Production [CRISPR/Cas9]
GEO Series GSE130510. Arabidopsis thaliana. 4 samples. Type: Non-coding RNA profiling by high throughput sequencing.
Latent HIV infection disrupts cell-intrinsic innate immunity
GEO Series GSE174380. Homo sapiens. 24 samples. Type: Expression profiling by high throughput sequencing.
A defect in G-quadruplex binding disrupts AID chromatin localization
GEO Series GSE136959. Mus musculus. 12 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Disruption of Mitochondria-Associated Endoplasmic Reticulum Membrane (MAM) integrity identified in FUS‑mutant oligodendroglial progeny from human induced pluripotent stem cells
GEO Series GSE239403. Homo sapiens. 15 samples. Type: Expression profiling by high throughput sequencing.
Targeted disruption of DNMT1, 3A and 3B in human embryonic stem cells
GEO Series GSE63281. Homo sapiens; Mus musculus. 34 samples. Type: Methylation profiling by high throughput sequencing.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.