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1,921 results for “Incidents”
Standardized Incidence Ratio of developing a malignancy in the Eye, Orbit and their adnexa after a first primary elsewhere in the body.
<p>Standardized Incidence Ratio of Eye, Orbit and their adnexa after a first primary elsewhere in the body.</p>
Data from: Body mass index, diet, physical inactivity and the incidence of dementia in one million UK women
Objective: To help determine whether mid-life obesity is a cause of dementia, and whether low BMI, low caloric intake and physical inactivity are causes or merely consequences of the gradual onset of dementia, we recorded these factors early in a large 20-year prospective study and related them to dementia detection rates separately during follow-up periods 0-4, 5-9, 10-14 and 15+ years. Methods: 1,136,846 UK women, mean age 56 (SD=5) years, were recruited in 1996-2001 and asked about height, weight, caloric intake and inactivity. They were followed until 2017 by electronic linkage to National Health Service records, detecting hospital admissions with mention of dementia. Cox regression yielded adjusted rate ratios (RRs) for first dementia detection during particular follow-up periods. Results: 15 years after the baseline survey only 1% were lost to follow-up and 89% remained alive with no detected dementia, of whom 18,695 had dementia detected later, at mean age 77 (SD=4) years. Dementia detection during years 15+ was associated with baseline obesity (BMI 30+ versus 20-24 kg/m2: RR=1.21, 95% CI 1.16-1.26; p<0.0001), but not clearly with low BMI, low caloric intake or inactivity at baseline. The latter three factors were associated with dementia rates during the first decade, but these associations weakened substantially over time, approaching null after 15 years. Conclusions: Mid-life obesity may well be a cause of dementia. In contrast, behavioural changes due to preclinical disease could largely or wholly account for associations of low BMI, low caloric intake and inactivity with dementia detection during the first decade.
Incidents of aggression in German psychiatric hospitals: Is there an increase?
<p><b>Introduction</b>: In a meta-analysis of international studies, 17% of admitted patients in psychiatric hospitals had shown violent behaviour towards others. Reported data from studies in Germany were considerably lower until now. However, studies referred to single hospitals and data quality was questionable. It is under discussion whether there is an increase of violent incidents.</p> <p><b>Methods</b>: In a group of 10 hospitals serving about half of the population of the Federal State of Baden-Wuerttemberg with 11 million inhabitants, the staff observation aggression scale, revised (SOAS-R) was introduced into the electronic charts as part of routine documentation. Data recording was strongly supported by staff councils and unions. Complete data is now available for the year 2019. For one hospital, data is available since 2006. Due to some doubts with respect to fully covering self-directed aggression, we restricted the analysis to aggression toward others and toward objects.</p> <p><b>Results:</b> In 2019, 17,599 aggressive incidents were recorded in 64,367 admissions (1,660 staying forensic psychiatric patients included). 5,084 (7.90%) of the admitted cases showed aggressive behaviour towards others. Variation between hospitals was low to modest (SD=1.50). The mean SOAS-R score was 11.8 (SD between hospitals 1.20 %). 23% of the incidents resulted in bodily harm. The percentage of patients with violent behaviour was highest among patients with organic disorders (ICD-10 F0) and lowest among patients with addictive or affective disorders (F1, F3, F4). Forensic psychiatry had the highest proportion of cases with aggressive behaviour (20.54 %), but the number of incidents per bed was lower than in general adult psychiatry and child and adolescent psychiatry, indicating a lower risk for staff. In the hospital with long-time recordings available, an increase could be observed since 2010, with considerable variation between years. </p> <p><b>Conclusion:</b> This is the most robust estimate of the frequency of violent incidents in German psychiatric hospitals so far. The incidence is about half of what has been reported internationally, probably due to sample selection bias in previous studies and a relatively high number of hospital beds in Germany. Available data suggests an increase in violent incidents over the last ten years; however, it is unclear to what extent this is due to increased reporting.</p>
Data from: Lifetime cumulative incidence of dementia in a community-dwelling elderly population in Japan
Objective: The aim of this study is to estimate the lifetime cumulative incidence of dementia and its subtypes from a community-dwelling elderly population in Japan. Methods: A total of 1,193 community-dwelling Japanese individuals without dementia, aged 60 years or older, were followed-up prospectively for 17 years. The cumulative incidence of dementia was estimated based on a death- and dementia-free survival function and the hazard functions of dementia at each year, which were computed by using a Weibull proportional hazards model. The lifetime risk of dementia was defined as the cumulative incidence of dementia at the point in time when the survival probability of the population was estimated to be less than 0.5%. Results: During the follow-up, 350 subjects experienced some type of dementia; among them, 191 subjects developed Alzheimer's disease (AD) and 117 developed vascular dementia (VaD). The lifetime risk of dementia was 55% (95% confidence interval [CI], 49-60%). Women had an approximately 1.5-time greater lifetime risk of dementia than men (65% [57-72%] vs. 41% [33-49%]). The lifetime risks of developing AD and VaD were 42% (35-50%) and 16% (12-21%) in women, versus 20% (7-34%) and 18% (13-23%) in men, respectively. Conclusion: Lifetime risk of all dementia for Japanese elderly was substantial at approximately 50% or higher. This study suggests that the lifetime burden attributable to dementia in contemporary Japanese communities is immense.
Data from: Incidence of frontotemporal lobar degeneration in Italy: the Salento-Brescia Registry study
Objective The goal of the present work, based on a collaborative research registry in Italy (the Salento-Brescia Registry), was to assess the incidence of frontotemporal lobar degeneration (FTLD) and to define the frequencies of different FTLD phenotypes in the general population. Methods The study was conducted from January 1, 2017, to December 31, 2017, in 2 Italian provinces: Lecce (in Puglia) in the south (area 2,799.07 km2, inhabitants 802,082) and Brescia (in Lombardy) in the north (area 4,785.62 km2, inhabitants 1,262,678). During the study period, all new cases of FTLD (incident FTLD) were counted, and all patients' records were reviewed. The incidence was standardized to the Italian general population in 2017. Results In the 2 provinces, 63 patients with FTLD were diagnosed. The incidence rate for FTLD was 3.05 (95% confidence interval [CI] 2.34–3.90) per 100,000 person-years (py), while the age-sex standardized incidence rate was 3.09 (95% CI 2.95–3.23) per 100,000 py. In the Italian population, the lifetime risk was 1:400. There was a progressive increase in FTLD incidence across age groups, reaching its peak in the 75- to 79-year-old group, with an incidence rate of 15.97 (95% CI 8.94–26.33) per 100,000 py. The behavioral variant of frontotemporal dementia was the most common phenotype (37%). No difference in crude incidence rate between the 2 provinces was observed. Conclusion FTLD is a more common form of dementia than previously recognized, with a risk spanning in a wide age range and with maximum incidence in the mid-70s. Improved knowledge of FTLD epidemiology will help to provide appropriate public health service policies.
Data from: Axial length elongation and myopia incidence increase in primary school-age children: 3-year follow-up study
<p>Objective: To investigate the axial length (AL) elongation in primary school-age children during 3-year follow-up period, and evaluate the associations of AL elongation with spherical equivalent (SE), AL at baseline, body height and weight.</p> <p>Design: A 3-year observational cohort study from 2014 to 2017.</p> <p>Setting: Jinshan Hospital of Fudan University in Shanghai.</p> <p>Methods: A total of 452 children successfully completed their measurements in the 3-year follow-up period. Among those children, the mean age was 6.9 ± 0.7 years, ranging from 6 years to 8 years, and 217 (42.7%) were boys. AL was measured with an ocular biometry system. Refractive error was measured using an auto-refractor without cycloplegia.</p> <p>Results: The mean changes of ALs were 0.27 ± 0.28 mm, 0.52 ± 0.40 mm, and 0.89 ± 0.51mm over 1 year, over 2 years and over 3 years, respectively. The mean changes of Spherical equivalents (SEs) were -0.27 ± 0.80 D, -0.56 ± 1.00 D, and -0.95 ± 1.41 D over 1 year, over 2 years and over 3 years, respectively. Multivariate linear regression analysis revealed that mean change of AL was associated with mean change of SE at all points (all P < 0.001). In addition, linear regression analysis revealed that AL elongation in the 3-year follow-up period was associated with AL at baseline (R2 = 0.009, P = 0.045).</p> <p>Conclusions: AL elongation is relatively high in the primary school-age children in Jinshan District, Shanghai. Effect strategies are needed to control AL elongation.</p> <p> </p>
Data from: Epidemiological survey of the feasibility of broadband ultrasound attenuation measured using calcaneal quantitative ultrasound to predict the incidence of falls in the middle aged and elderly
Objectives: We investigated whether calcaneal quantitative ultrasound (QUS-C) is a feasible tool for predicting the incidence of falls. Design: Prospective epidemiological cohort study. Setting: Community-dwelling people sampled in central western Taiwan. Participants: A cohort of community-dwelling people who were ≥40 years old (men: 524; women: 676) in 2009–2010. Follow-up questionnaires were completed by 186 men and 257 women in 2012. Methods: Structured questionnaires and broadband ultrasound attenuation (BUA) data were obtained in 2009–2010 using QUS-C, and follow-up surveys were done in a telephone interview in 2012. Using a binary logistic regression model, the risk factors associated with a new fall during follow-up were analysed with all significant variables from the bivariate comparisons and theoretically important variables. Primary outcome measures: The incidence of falls was determined when the first new fall occurred during the follow-up period. The mean follow-up time was 2.83 years. Results: The total incidence of falls was 28.0 per 1000 person-years for the ≥40 year old group (all participants), 23.3 per 1000 person-years for the 40–70 year old group, and 45.6 per 1000 person-years for the ≥70 year old group. Using multiple logistic regression models, the independent factors were current smoking, living alone, psychiatric drug usage and lower BUA (OR 0.93; 95% CI 0.88 to 0.99, p<0.05) in the ≥70 year old group. Conclusions: The incidence of falls was highest in the ≥70 year old group. Using QUS-C-derived BUA is feasible for predicting the incidence of falls in community-dwelling elderly people aged ≥70 years.
Data from: Incidence rate of community-acquired pneumonia in adults: a population-based prospective active surveillance study in three cities in South America
OBJECTIVE: To determine the incidence rate and mortality of community-acquired pneumonia (CAP) in adults in three cities in Latin America during a three-year period. DESIGN: Prospective population based study. SETTING: Healthcare facilities (outpatient centers and hospitals) in the cities of General Roca (Argentina), Rivera (Uruguay) and Concepcion (Paraguay). PARTICIPANTS: 2302 adults aged 18 years and older with CAP were prospectively enrolled between January 2012 and March 2015. MAIN OUTCOME MEASURES: Incidence rate of CAP in adults, predisposing conditions for disease, mortality at 14 days and at one year were estimated. Incidence rate of CAP, within each age group, was calculated by dividing the number of cases by the person-years of disease-free exposure time based on the last census; incidence rates were expressed per 1000 person-years. RESULTS: Median age of participants was 66 years, 46.44 % were men, 68% were hospitalized. Annual incidence rate was 7.03 (CI95% 6.64-7.44) per 1000 person-years in General Roca, 6.33 (CI95% 5.92-6.78) per 1000 person-years in Rivera and 1.76 (CI95% 1.55-2.00) per 1000 person-years in Concepcion. Incidence rates were highest in participants aged over 65 years. 82.4% had at least one predisposing condition and 48% had 2 or more (multi-morbidity). Chronic heart disease (43.6%) and smoking (37.3%) were the most common risk factors. 14-day mortality rate was 12.1% and one-year mortality was 24.9%. Multi-morbidity was associated with an increased risk of death at 14 days (OR 2.91; 2.23 to 3.80) and at 1 year (OR 3.00; 2.44 to 3.70). CONCLUSIONS: We found a high incidence rate of CAP in adults, ranging from 1.76 to 7.03 per 1000 person-years, in three cities in South America, disclosing the high burden of disease in the region. Efforts to improve prevention strategies are needed.
Data from: Early antiretroviral therapy and potent second-line drugs could decrease HIV incidence of drug resistance
Early initiation of antiretroviral therapy (ART) reduces the risk of drug-sensitive HIV transmission but may increase the transmission of drug-resistant HIV. We used a mathematical model to estimate the long-term population-level benefits of ART and determine the scenarios under which earlier ART (treatment at 1 year post-infection, on average) could decrease simultaneously both total and drug-resistant HIV incidence (new infections). We constructed an infection-age-structured mathematical model that tracked the transmission rates over the course of infection and modelled the patients' life expectancy as a function of ART initiation timing. We fitted this model to the annual AIDS incidence and death data directly, and to resistance data and demographic data indirectly among men who have sex with men (MSM) in San Francisco. Using counterfactual scenarios, we assessed the impact on total and drug-resistant HIV incidence of ART initiation timing, frequency of acquired drug resistance, and second-line drug effectiveness (defined as the combination of resistance monitoring, biomedical drug efficacy and adherence). Earlier ART initiation could decrease the number of both total and drug-resistant HIV incidence when second-line drug effectiveness is sufficiently high (greater than 80%), but increase the proportion of new infections that are drug resistant. Thus, resistance may paradoxically appear to be increasing while actually decreasing.
Electromagnetic Calorimeter Shower Images with Variable Incidence Angle and Position
<p>Each file is a collection of 500,000 (or 400,000 in the case of positrons) calorimeter showers corresponding to the particle specified in the file name (eplus = positrons, gamma = photons, piplus = charged pions). </p> <p>The calorimeter we built is segmented longitudinally into three layer with different depths and granularities. In units of mm, the three layers have the following (eta, phi, z) dimensions:<br> Layer 0: (5, 160, 90) | Layer 1: (40, 40, 347) | Layer 2: (80, 40, 43)</p> <p>In the HDF5 files, the `energy` entry specifies the true energy of the incoming particle in units of GeV. `layer_0`, `layer_1`, and `layer_2` represents the energy deposited in each layer of the calorimeter in an image data format. Given the segmentation of each calorimeter layer, these images have dimensions 3x96 (in layer 0), 12x12 (in layer 1), and 12x6 (in layer 3). The `overflow` contains the amount of energy that was deposited outside of the calorimeter section we are considering. The fields `x0`, `y0`, `z0`, `t0`, `px`, `py`, `pz` provide position and kinematic information of incident particles upon impact. </p>
ATOPIC DERMATITIS INCIDENT LEVEL, DIAGNOSTIC CRITERIA AND PROGNOSTIC IMPORTANCE.
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Estimated numbers of incident cases of pandemic influenza in Prussian army camps around Arnsberg (Germany) 1918/19
<p>Hiroshi Nishiura estimated the numbers of (incident) cases of influenza in Prussian army camps in the region of Arnsberg (Germany) from reported death cases during September 1918 and January 1919. The estimated numbers are presented as dashed line in Figure 1 of [1] ("Onset"). We extracted the estimated numbers of incident cases from Figure 1. For our purpose, the accuracy of the extracted numbers of incident cases is sufficient. In case of need for higher accuracy, we recommend to refer to the original paper [1]. Note that the numbers of incident cases are <strong>estimates</strong> (as detailed in [1]), the reported original data are the number of fatalities presented as solid line in Figure 1 ("Death") [1]. The numbers of fatalities are kindly given as an electronic supplement of [1] ("Additional File 1").</p> <p>The variable "Day" is counted from September 9, 1918, onwards.</p> <p>Reference:<br>1. Nishiura H: Time variations in the transmissibility of pandemic influenza in Prussia, Germany, from 1918–19. Theor Biol Med Model 4, 20, 2007. DOI 10.1186/1742-4682-4-20</p>
PREVALENCE ANALYSIS INCIDENCE OF UPPER RESPIRATORY COVID-19 - INFECTED PATIENTS
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Incidence of TB by country of origin - Estrie region
<p>The identification and treatment of latent tuberculosis infection (LTBI) among immigrants from high-incidence regions who move to low-incidence countries is generally considered an ineffective strategy because only ≈14% of them comply with the multiple steps of the 'cascade of care' and complete treatment. In the Estrie region of Canada, a refugee clinic was opened in 2009. One of its goals is LTBI management. Between 2009-2020, 5131 refugees were evaluated. To determine the efficacy and benefit-cost ratio of this intervention, records of refugees seen in 2010-14 (n=1906) and 2018-19 (n=1638) were reviewed. Cases of tuberculosis (TB) among our foreign-born population occurring before (1997-2008) and after (2009-2020) setting up the clinic were identified. All costs associated with TB or LTBI were measured. Out of 441 patients offered LTBI treatment, 374 (85%) were compliant. Adding other losses, overall compliance was 69%. To prevent one case of TB, 95.1 individuals had to be screened and 11.9 treated, at a cost of $16,056. After discounting, each case of TB averted represented $32,631, for a benefit-cost ratio of 2.03. Among nationals of the 20 countries where refugees came from, incidence of TB decreased from 68.2 (1997-2008) to 26.3 per 100,000 person-years (2009-2020). Incidence among persons from high-incidence countries not targeted by the intervention did not change (12.4 vs 12.8 per 100,000) Among refugees settling in our region, 69% completed the LTBI cascade of care, leading to a 61% reduction in TB incidence. This intervention was cost-beneficial. Key factors for this satisfactory compliance included: close collaboration with community organizations, its integration within a comprehensive package of medical care for the whole family, its delivery shortly after arrival, shorter rifampicin-based treatment, and risk-based selection of patients to be treated. Management of LTBI among migrants should not be considered a lost cause.</p>
Raw data and SPSS analysis for the article Bacterial and fungal co-infections among ICU COVID-19 hospitalized patients in a Palestinian hospital: Incidence and antimicrobial stewardship
<p>The attached data is related to a study with proposes to investigate the burden of bacterial and fungal co-infections outcomes on COVID-19 patients. It is a single-center cross-sectional study of hospitalized COVID-19 patients at Beit-Jala hospital in Palestine. The study included 321 hospitalized patients admitted to the ICU between June 2020 and March 2021 aged ≥20 years,</p> <p><b>Background:</b> Diagnosis of co-infections with multiple pathogens among hospitalized COVID-19 patients can be jointly challenging and very essential for appropriate treatment, shortening hospital stay and preventing antimicrobial resistance. This study proposes to investigate the burden of bacterial and fungal co-infections outcomes on COVID-19 patients. It is a single center cross-sectional study of hospitalized COVID-19 patients at Beit-Jala hospital in Palestine.</p> <p><b>Methods: </b>The study included 321 hospitalized patients admitted to the ICU between June 2020 and March 2021 aged ≥20 years, with a confirmed diagnosis of COVID-19 via RT-PCR conducted on a nasopharyngeal swab. The patient's information was gathered using graded data forms from electronic medical reports.</p> <p><b>Results:</b> The diagnosis of bacterial and fungal infection was proved through the patient`s clinical presentation and positive blood or sputum culture results. All cases had received empirical antimicrobial therapy before the ICU admission, and different regimens during the ICU stay. The rate of bacterial co-infection was 51.1%, mainly from gram-negative isolates (Enterobacter species and K.pneumoniae). The rate of fungal co-infection caused by A.fumigatus was 48.9%, and the mortality rate was 8.1%. However, it is unclear if it had been attributed to SARS-CoV-2 or coincidental.</p>
Supplemental data: The association of dilated perivascular spaces with cognitive decline and incident dementia
<p><span><b>Objective:</b></span></p> <p><span>To determine if severe perivascular space (PVS) dilation is associated with longitudinal cognitive decline and incident dementia over four and eight years respectively, we analyzed data from a prospective cohort study.</span></p> <p><span><b>Methods: </b></span></p> <p>414 community dwelling older adults aged 72-92 were assessed at baseline and biennially for up to eight years, with cognitive assessments, consensus dementia diagnoses and 3T MRI imaging. The numbers of PVS in two representative slices in the basal ganglia (BG) and centrum semiovale (CSO) were counted and severe PVS pathology defined as the top quartile. The effects of severe PVS pathology in i) either region; ii) both regions; and those with iii) severe BG PVS and iv) severe CSO PVS were examined. White matter hyperintensity volume, cerebral microbleed number and lacune number were calculated.</p> <p><span><b>Results:</b></span></p> <p>Participants with severe PVS pathology in both regions or in the CSO alone had greater decline in global cognition over four years, even after adjustment for the presence of other small vessel disease neuroimaging markers. The presence of severe PVS pathology in both regions was an independent predictor of dementia across eight years (OR 2.91, 95%CI 1.43–5.95, p= 0.003). Further, the presence of severe PVS pathology in all groups examined was associated with greater dementia risk at either year four or six.</p> <p><span><b>Conclusions: </b></span></p> <p>Severe PVS pathology is a marker for increased risk of cognitive decline and dementia, independent of other small vessel disease markers. The differential cognitive associations for BG and CSO PVS may represent differences in their underlying pathology.</p>
Worldwide incidence and prevalence of NMO: A systematic review
<p><strong>Objective</strong>: Since the last epidemiologic review of neuromyelitis optica/neuromyelitis optica spectrum disorder (NMO/NMOSD), 22 additional studies have been conducted. We systematically review the worldwide prevalence, incidence, and basic demographic characteristics of NMOSD and provide a critical overview of studies.</p> <p><strong>Methods</strong>: PubMed, Ovid MEDLINE, and Embase using Medical Subject Headings and keyword search terms and reference lists of retrieved articles were searched from 1999 until August 2019. We collected data on the country; region; methods of case assessment and aquaporin-4 antibody (AQP4-Ab) test; study period; limitations; incidence (per 100,000 person-years); prevalence (per 100,000 persons); and age-, sex-, and ethnic group–specific incidence or prevalence.</p> <p><strong>Results</strong>: We identified 33 relevant articles. The results indicated the highest estimates of incidence and prevalence of NMOSD in Afro-Caribbean region (0.73/100 000 person-years [95% CI: 0.45–1.01] and 10/100 000 persons [95% CI: 6.8–13.2]). The lowest incidence and prevalence of NMOSD were found in Australia and New Zealand (0.037/100 000 person-years [95% CI: 0.036–0.038] and 0.7/100,000 persons [95% CI: 0.66–0.74]). There was prominent female predominance in adults and the AQP4-Ab–seropositive subpopulation. The incidence and prevalence peaked in middle-aged adults. African ethnicity had the highest incidence and prevalence of NMOSD, whereas White ethnicity had the lowest. No remarkable trend of incidence was described over time.</p> <p><strong>Conclusion</strong>: NMOSD is a rare disease worldwide. Variations in prevalence and incidence have been described among different geographic areas and ethnicities. These are only partially explained by different study methods and NMO/NMOSD definitions, highlighting the need for specifically designed epidemiologic studies to identify genetic effects and etiologic factors.</p>
FactDrill: A Data Repository of Fact-checked Social Media Content to Study Fake News Incidents in India
<p>A dataset containing 22,435 fact-checked social media content to study fake news incidents in India. The dataset comprises news stories from 2013 to the year 2020, covering 13 different languages spoken in the country. There are 14 different attributes present in the dataset.</p>
FIGURE 7 in First comprehensive study on distribution frequency and incidence of seed-borne pathogens from cereal and legume crops in Sri Lanka
FIGURE 7. Uprooted seedlings of a Arachis hypogea b Vigna radiata and c Vigna sinensis.
Diversity and Inclusion (D&I)- Related AI Incidents Repository
<p>This repository is a part of the research "AI for All: Identifying Diversity and Inclusion Related AI incidents".</p> <p>We developed the first version of D&I-related AI incidents repository based on the AIID database. Each record in this repository encompasses details such as the incident ID, title, description, date, alleged deployer of AI system, alleged developer of AI system, and alleged harmed or nearly harmed parties. Each incident ID is linked to a corresponding article for a more detailed account of the incident. Further, in the repository, we added the status in relation to D&I, diversity attributes such as age, gender, ethnicity, race and so on, and the reason supporting our determination. We have outlined three categories under the "status" column to categorize the incidents: related to D&I (R), not related to D&I (NR), and more information required (MIR).</p>
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.