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ShareScore release 0.9.0
Dataset results
84 results for “Biomimetic”
Clinical Efficacy of Biomimetic Hydroxyapatite in the Treatment of Molar Incisor Hypomineralization.
ClinicalTrials.gov study NCT04808180. IPD Sharing: NO. Countries: 1. Publications: 0.
The Biomimetic Stent and Vascular Functions Study
ClinicalTrials.gov study NCT05447052. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Reminerlization Potential of Innovative Biomimetic Material in Caries White Spot Lesions
ClinicalTrials.gov study NCT03823612. IPD Sharing: Not stated. Countries: 1. Publications: 0.
3D Biomimetic Spine Unit Model Through the Integration of Bioprinting and Transcriptomics (CDP-SUBT)
ClinicalTrials.gov study NCT07250126. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Biomimetic Cell Stimulation with Graphene Oxide Antigen Presenting Platform (GO-APP) for Developing T Cell-Based Therapies [scRNA-Seq]
GEO Series GSE233290. Homo sapiens. 4 samples. Type: Expression profiling by high throughput sequencing.
Data from: Kinetic study of catalytic CO2 hydration by metal-substituted biomimetic carbonic anhydrase model complexes
Open the record for dataset details and reuse information.
Engineering biomimetic bone marrow niche with gene modified Mesenchymal Stromal Cells for ex vivo culture of human Hematopoietic Stem and Progenitor cells
GEO Series GSE292072. Homo sapiens. 8 samples. Type: Expression profiling by high throughput sequencing.
A Physiological Biomimetic Culture System for Pig and Human Heart Slices
GEO Series GSE133723. Sus scrofa. 11 samples. Type: Expression profiling by high throughput sequencing.
The Clinical and Radiographic Outcomes of a 3D-printed Patient-specific Biomimetic Bone Substitute in Maxillofacial Indications: an Interventional, Multi-centred, Open-label, Post-market Clinical Inve
ClinicalTrials.gov study NCT04773847. IPD Sharing: YES. Countries: 0. Publications: 0.
Spaceflight Analogue Culture Enhances the Host-Pathogen Interaction Between Salmonella and a 3-D Biomimetic Intestinal Co-Culture Model
Physical forces associated with spaceflight and spaceflight analogue culture regulate a wide range of physiological responses by both bacterial and mammalian cells that can impact infection. However, our mechanistic understanding of how these environments regulate host-pathogen interactions in humans is poorly understood. Using a spaceflight analogue low fluid shear culture system, we investigated the effect of Low Shear Modeled Microgravity (LSMMG) culture on the colonization of Salmonella Typhimurium in a 3-D biomimetic model of human colonic epithelium containing macrophages. RNA-seq profiling of stationary phase wild type and delta hfq mutant bacteria alone indicated that LSMMG culture induced global changes in gene expression in both strains and that the RNA-binding protein Hfq played a significant role in regulating the transcriptional response of the pathogen to LSMMG culture. However, a core set of genes important for adhesion, invasion, and motility were commonly induced in both strains. LSMMG culture enhanced the colonization (adherence, invasion and intracellular survival) of Salmonella in this advanced model of intestinal epithelium using a mechanism that was independent of Hfq. Although S. Typhimurium delta hfq mutants are normally defective for invasion when grown as conventional shaking cultures, LSMMG conditions unexpectedly enabled high levels of colonization by an isogenic hfq mutant. In response to infection with either the wild type or mutant, host cells upregulated transcripts involved in inflammation, tissue remodeling, and wound healing during intracellular survival. Interestingly, infection by the hfq mutant led to fewer transcriptional differences between LSMMG- and control-infected host cells relative to infection with the wild type strain. This is the first study to investigate the effect of LSMMG culture on the interaction between S. Typhimurium and a 3-D model of human intestinal tissue. These findings advance our understanding of how physical forces can impact the early stages of human enteric salmonellosis.
Biomimetic multifunctional nanodrugs enable regulating abnormal tumor metabolism and amplifying PDT-induced immunotherapy for synergistically enhanced tumor ablation
GEO Series GSE237010. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
Spatial transcriptomic validation of a biomimetic model of fibrosis enables re-evaluation of a therapeutic antibody targeting LOXL2
GEO Series GSE255705. Homo sapiens. 48 samples. Type: Expression profiling by high throughput sequencing.
Biomimetic model of human small airways reveals functional impacts of the cystic fibrosis microenvironment on monocytes and macrophages
GEO Series GSE311629. Homo sapiens. 35 samples. Type: Expression profiling by high throughput sequencing.
Biomimetic Strategy Driven Deubiquitination for Enhanced Ferroptosis and Cancer Immunotherapy
GEO Series GSE309315. Mus musculus. 12 samples. Type: Expression profiling by high throughput sequencing.
Biomimetic strategy for cartilage formation: synergy of stem cell micro-aggregates and supramolecular peptide nanofibers
GEO Series GSE133727. Homo sapiens. 20 samples. Type: Expression profiling by high throughput sequencing.
Biologically-inspired melt electrowriting for the generation of highly biomimetic functional myocardium
GEO Series GSE281166. Homo sapiens. 8 samples. Type: Expression profiling by high throughput sequencing.
Biomimetic Design of Manganese-Doped Carbon Dot Nanozymes with Ultrahigh SOD-Like Activity for ALS Management
GEO Series GSE289958. Mus musculus. 12 samples. Type: Expression profiling by high throughput sequencing.
A biomimetic calcium phosphate nanowire coating on titanium surface enhances osteoimmunomodulation and osteointegration
GEO Series GSE250308. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
The multidirectional in-situ osteogenesis pattern based on biomimetic mineralized dual-crosslinked Fibrinogen-GelMA microspheres in the maxillary sinus region
GEO Series GSE247540. Homo sapiens. 12 samples. Type: Expression profiling by high throughput sequencing.
The multidirectional in-situ osteogenesis pattern based on biomimetic mineralized dual-crosslinked Fibrinogen-GelMA microspheres in the maxillary sinus region II
GEO Series GSE256504. Homo sapiens. 12 samples. Type: Expression profiling by high throughput sequencing.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.