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Dataset results
115 results for “Chemical Profiles”
Dissecting the epigenome dynamics in human immune cells upon viral and chemical exposure by multimodal single-cell profiling
GEO Series GSE306525. Homo sapiens. 92 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Gene expression profiles of rat tissues surrounding Vcap xenograft tumors with chemical or physical denervation.
GEO Series GSE28717. Rattus norvegicus. 16 samples. Type: Expression profiling by array.
Transcriptional profiling to identify physical-chemical properties detrimental to nanomaterial-induced pulmonary response (part 4)
GEO Series GSE60800. Mus musculus. 70 samples. Type: Expression profiling by array.
Distinct transcriptional profiles in rat thyroid glands after developmental exposure to three in vitro thyroperoxidase inhibiting chemicals
GEO Series GSE242162. Rattus norvegicus. 29 samples. Type: Expression profiling by high throughput sequencing.
Transcriptional profiling to identify physical-chemical properties detrimental to nanomaterial-induced pulmonary response (part 2)
GEO Series GSE60798. Mus musculus. 69 samples. Type: Expression profiling by array.
Effect of epigenotoxic chemicals on transcriptomic profiles of human induced pluripotent stem cells
GEO Series GSE180454. Homo sapiens. 20 samples. Type: Expression profiling by high throughput sequencing; Methylation profiling by array; Methylation profiling by high throughput sequencing.
Base-resolution m5C profiling across the mammalian transcriptome by bisulfite-free enzyme-assisted chemical labeling approach
GEO Series GSE242724. Mus musculus; Homo sapiens. 104 samples. Type: Methylation profiling by high throughput sequencing.
Combining phenotypic profiling and targeted RNA-Seq reveals linkages between transcriptional perturbations and chemical effects on cell morphology: Retinoic acid as an example
GEO Series GSE200845. Homo sapiens. 372 samples. Type: Expression profiling by high throughput sequencing; Other.
CAT-seq: A Chemical Strategy for Subcellular-Resolved RNA Profiling and Synchronous Multi-omics Investigation
GEO Series GSE255007. Homo sapiens; Mus musculus. 38 samples. Type: Expression profiling by high throughput sequencing; Other.
DNA methylation profiles in human iPSC-derived neurosphere exposed to environmental chemicals
GEO Series GSE235146. Homo sapiens. 6 samples. Type: Methylation profiling by array.
Transcriptome-wide Profiling of N6‑Methyladenosine via a Selective Chemical Labeling Method
GEO Series GSE185753. Homo sapiens. 7 samples. Type: Methylation profiling by high throughput sequencing.
Assessing the Impact of Metabolic Competence on Estrogenic Chemical Bioactivity in High-Throughput Profiling Assays
GEO Series GSE296915. Homo sapiens. 0 samples. Type: Expression profiling by high throughput sequencing.
Comparative chemical-genomic profiling of plant-based hydrolysate toxins enables predictive assessment of responses to complex mixtures
GEO Series GSE186866. Saccharomyces cerevisiae. 151 samples. Type: Other.
Bioactivity screening of environmental chemicals using imaging-based high-throughput phenotypic profiling
Open the record for dataset details and reuse information.
Combining phenotypic profiling and targeted RNA-Seq reveals linkages between transcriptional perturbations and chemical effects on cell morphology: Retinoic acid as an example
Open the record for dataset details and reuse information.
Neglected very-long-chain hydrocarbons and the incorporation of body surface areas reveal novel perspectives for chemical profile analysis in insects
<p>Most of what we know about insect cuticular hydrocarbons (CHCs) has been informed by analyses with gas-chromatography coupled with mass spectrometry (GC-MS). However, this analysis technique has its limit, particularly in detecting compounds in a chain length range beyond around C40. Here, we attempt to differentiate the range of CHCs detectable by GC-MS with the largely neglected very-long-chain CHC range up to C58 analyzed by silver-assisted laser desorption/ionization mass spectrometry (Ag-LDI-MS), in seven species of the order Blattodea. For all tested species we unveiled a considerable range of very-long-chain CHCs not detectable by traditional GC-MS technology. This strongly suggests that general studies on insect CHCs routinely miss compounds in that range, and we encourage future studies to implement technologies capable of detecting very-long-chain CHCs. Furthermore, we implement 3D scanned insect body surface areas when quantifying CHC amounts per GC-MS, as Ag-LDI-MS is less suited to quantify total CHC contents. Proportional CHC distributions differed considerably when adjusted for body surface areas, suggesting the importance of their consideration. Moreover, correlations between body surface areas and GC-MS assessed CHC amounts were not significant, further hinting the inaccessibility of whole CHC profile ranges by this technique, potentially by missing the clearly present very-long-chain CHCs.</p>
Figure 1 from: Todorova N, Rangelov M, Dincheva I, Badjakov I, Enchev V, Markova N (2022) Potential of hydroxybenzoic acids from Graptopetalum paraguayense for inhibiting of herpes simplex virus DNA polymerase – metabolome profiling, molecular docking and quantum-chemical analysis. Pharmacia 69(1): 113-123. https://doi.org/10.3897/pharmacia.69.e79467
Figure 1 Graptopetalum paraguayense E. Walther.
Figure 4 from: Todorova N, Rangelov M, Dincheva I, Badjakov I, Enchev V, Markova N (2022) Potential of hydroxybenzoic acids from Graptopetalum paraguayense for inhibiting of herpes simplex virus DNA polymerase – metabolome profiling, molecular docking and quantum-chemical analysis. Pharmacia 69(1): 113-123. https://doi.org/10.3897/pharmacia.69.e79467
Figure 4 Fitting of phenolic acids in the DNA polymerase pocket.
Chemical Profiling of Colorectal and Pancreatic Cancers Using Breath Analysis - Feasibility Study
ClinicalTrials.gov study NCT05400408. IPD Sharing: NO. Countries: 1. Publications: 0.
Effect of epigenotoxic chemicals on transcriptomic profiles of human induced pluripotent stem cells [RNA-seq]
GEO Series GSE180452. Homo sapiens. 7 samples. Type: Expression profiling by high throughput sequencing.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.