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1,960 results for “Cortex”
ASIC2 Deletion in Medial Prefrontal Cortex Enhances Social Dominance in Mice
<p>Social dominance is essential for maintaining a stable social society and has well-established positive and negative impacts on sociable animals, including humans. However, the regulatory mechanisms governing social dominance, as well as the crucial regulators and biomarkers involved, remain poorly understood. We discover that mice lacking acid-sensing ion channel 2 (ASIC2) exhibit a persistent higher social dominance ranking compared to their wild-type cagemates. Conversely, the overexpression of ASIC2 in the medial prefrontal cortex (mPFC) reverses the dominance hierarchy observed in ASIC2 knockout mice. ASIC2 deletion prolongs the inactivation time of ASICs, resulting in enhanced ASIC-dependent synaptic transmission and plasticity in the mPFC through the protein kinase A signaling pathway. Furthermore, ASIC2 exhibits distinct functional roles in excitatory and inhibitory neurons, thereby modulating the balance of neuronal activities underlying social dominance behaviors—a phenomenon suggestive of a cell-subtype-specific mechanism. Finally, this research establishes a foundational understanding of the mechanisms governing social dominance formation, offering potential insights for the management or prevention of social disorders, such as depression and anxiety.</p>
Nonhuman Primate Reaching with Multichannel Sensorimotor Cortex Electrophysiology: broadband for indy_20170127_03
<p>This dataset supplements <a href="https://doi.org/10.5281/zenodo.583331">https://doi.org/10.5281/zenodo.583331</a> .<br> <br> <strong>General description.</strong> These data consist of extracellular neural recordings ("broadband") from primate subject "Indy", session identifier "indy_20170127_03".</p> <p><strong>Filtering. </strong>The data are sampled at 24414.0625 Hz and are unfiltered, except for an anti-aliasing filter built-in to the recording amplifier: a 4th order low-pass with a roll-off of 24 dB per octave at 7.5 kHz, operating at the sampling rate.</p> <p><strong>File format.</strong> The data are contained in an HDF5 formatted file, organized according to the <a href="https://github.com/NeurodataWithoutBorders/specification">Neurodata Without Borders (NWB) version 1.0.6</a> specification.</p> <p><strong>Datasets. </strong>A few of the relevant dataset paths are listed here for convenience. In the below, <em>n</em> refers to the number of recording channels and <em>k</em> refers to the number of samples.</p> <ul> <li>"/acquisition/timeseries/broadband/data" - k x n <ul> <li>The broadband neural recordings.</li> </ul> </li> <li>"/acquisition/timeseries/broadband/data/conversion" (scalar attribute) <ul> <li>When multiplied by each sample converts the data into units of volts.</li> </ul> </li> <li>"/acquisition/timeseries/broadband/timestamps" - k x 1 <ul> <li>Timestamps for each sample, seconds.</li> </ul> </li> <li>"/general/extracellular_ephys/electrode_map" - n x 3 <ul> <li>The relative coordinates of each electrode contact (x, y, z), meters.</li> </ul> </li> </ul> <p>Please refer to the <a href="https://doi.org/10.5281/zenodo.583331">master dataset</a> for further information.</p>
Nonhuman Primate Reaching with Multichannel Sensorimotor Cortex Electrophysiology: broadband for indy_20170124_01
<p>This dataset supplements <a href="https://doi.org/10.5281/zenodo.583331">https://doi.org/10.5281/zenodo.583331</a> .<br> <br> <strong>General description.</strong> These data consist of extracellular neural recordings ("broadband") from primate subject "Indy", session identifier "indy_20170124_01".</p> <p><strong>Filtering. </strong>The data are sampled at 24414.0625 Hz and are unfiltered, except for an anti-aliasing filter built-in to the recording amplifier: a 4th order low-pass with a roll-off of 24 dB per octave at 7.5 kHz, operating at the sampling rate.</p> <p><strong>File format.</strong> The data are contained in an HDF5 formatted file, organized according to the <a href="https://github.com/NeurodataWithoutBorders/specification">Neurodata Without Borders (NWB) version 1.0.6</a> specification.</p> <p><strong>Datasets. </strong>A few of the relevant dataset paths are listed here for convenience. In the below, <em>n</em> refers to the number of recording channels and <em>k</em> refers to the number of samples.</p> <ul> <li>"/acquisition/timeseries/broadband/data" - k x n <ul> <li>The broadband neural recordings.</li> </ul> </li> <li>"/acquisition/timeseries/broadband/data/conversion" (scalar attribute) <ul> <li>When multiplied by each sample converts the data into units of volts.</li> </ul> </li> <li>"/acquisition/timeseries/broadband/timestamps" - k x 1 <ul> <li>Timestamps for each sample, seconds.</li> </ul> </li> <li>"/general/extracellular_ephys/electrode_map" - n x 3 <ul> <li>The relative coordinates of each electrode contact (x, y, z), meters.</li> </ul> </li> </ul> <p>Please refer to the <a href="https://doi.org/10.5281/zenodo.583331">master dataset</a> for further information.</p>
Nonhuman Primate Reaching with Multichannel Sensorimotor Cortex Electrophysiology: broadband for indy_20170123_02
<p>This dataset supplements <a href="https://doi.org/10.5281/zenodo.583331">https://doi.org/10.5281/zenodo.583331</a> .<br> <br> <strong>General description.</strong> These data consist of extracellular neural recordings ("broadband") from primate subject "Indy", session identifier "indy_20170123_02".</p> <p><strong>Filtering. </strong>The data are sampled at 24414.0625 Hz and are unfiltered, except for an anti-aliasing filter built-in to the recording amplifier: a 4th order low-pass with a roll-off of 24 dB per octave at 7.5 kHz, operating at the sampling rate.</p> <p><strong>File format.</strong> The data are contained in an HDF5 formatted file, organized according to the <a href="https://github.com/NeurodataWithoutBorders/specification">Neurodata Without Borders (NWB) version 1.0.6</a> specification.</p> <p><strong>Datasets. </strong>A few of the relevant dataset paths are listed here for convenience. In the below, <em>n</em> refers to the number of recording channels and <em>k</em> refers to the number of samples.</p> <ul> <li>"/acquisition/timeseries/broadband/data" - k x n <ul> <li>The broadband neural recordings.</li> </ul> </li> <li>"/acquisition/timeseries/broadband/data/conversion" (scalar attribute) <ul> <li>When multiplied by each sample converts the data into units of volts.</li> </ul> </li> <li>"/acquisition/timeseries/broadband/timestamps" - k x 1 <ul> <li>Timestamps for each sample, seconds.</li> </ul> </li> <li>"/general/extracellular_ephys/electrode_map" - n x 3 <ul> <li>The relative coordinates of each electrode contact (x, y, z), meters.</li> </ul> </li> </ul> <p>Please refer to the <a href="https://doi.org/10.5281/zenodo.583331">master dataset</a> for further information.</p>
Dataset of Axon Segmentation and Centerlines, Acquired using a Two-photon Microscope in the Live Mouse Cortex
<p>This dataset contains 20 images of real axons that were published previously in Bass et al (2017). This subset dataset has been added labels of binary images for segmentation of the axons, and of centerline for tracing of the axons.</p> <p>We provide the following:</p> <ul> <li>Images-MAX: 2D images of axons (.png)</li> <li>Images-TIFF: 3D images of axons (.tiff)</li> <li>Labels-binary: Manual segmentation of the axons as binary images (.png)</li> <li>Labels-tracing: Manual tracing of the axons (.swc)</li> </ul> <p>This data was collected in the live mouse cortex, using a two-photon microscope, with a 40x objective, at zoom 4, and with a resolution of 512 × 512 pixels, 0.147 <em>μ</em>m per pixel for the <em>x</em>, <em>y</em> planes, and 1 <em>μ</em>m for the <em>z</em> plane. . </p> <p><strong>Please cite the following papers when using this dataset:</strong></p> <p>T. Dai, M. Dubois, K. Arulkumaran, J. Campbell, B. Billot, C. Bass, Z. Uslu, V. De Paola, C. Clopath, and A. A. Bharath. Deep reinforcement learning for subpixel neural tracking. <em>Medical Imaging with Deep Learning</em>. 2019.</p> <p>Bass C, Helkkula P, De Paola V, Clopath C, Bharath AA. Detection of axonal synapses in 3D two-photon images. Giniger E, ed. <em>PLoS ONE</em>. 2017;12(9):e0183309. doi:10.1371/journal.pone.0183309.</p>
Nonhuman Primate Reaching with Multichannel Sensorimotor Cortex Electrophysiology: broadband for indy_20161220_02
<p>This dataset supplements <a href="https://doi.org/10.5281/zenodo.583331">https://doi.org/10.5281/zenodo.583331</a> .<br> <br> <strong>General description.</strong> These data consist of extracellular neural recordings ("broadband") from primate subject "Indy", session identifier "indy_20161220_02".</p> <p><strong>Filtering. </strong>The data are sampled at 24414.0625 Hz and are unfiltered, except for an anti-aliasing filter built-in to the recording amplifier: a 4th order low-pass with a roll-off of 24 dB per octave at 7.5 kHz, operating at the sampling rate.</p> <p><strong>File format.</strong> The data are contained in an HDF5 formatted file, organized according to the <a href="https://github.com/NeurodataWithoutBorders/specification">Neurodata Without Borders (NWB) version 1.0.6</a> specification.</p> <p><strong>Datasets. </strong>A few of the relevant dataset paths are listed here for convenience. In the below, <em>n</em> refers to the number of recording channels and <em>k</em> refers to the number of samples.</p> <ul> <li>"/acquisition/timeseries/broadband/data" - k x n <ul> <li>The broadband neural recordings.</li> </ul> </li> <li>"/acquisition/timeseries/broadband/data/conversion" (scalar attribute) <ul> <li>When multiplied by each sample converts the data into units of volts.</li> </ul> </li> <li>"/acquisition/timeseries/broadband/timestamps" - k x 1 <ul> <li>Timestamps for each sample, seconds.</li> </ul> </li> <li>"/general/extracellular_ephys/electrode_map" - n x 3 <ul> <li>The relative coordinates of each electrode contact (x, y, z), meters.</li> </ul> </li> </ul> <p>Please refer to the <a href="https://doi.org/10.5281/zenodo.583331">master dataset</a> for further information.</p>
Nonhuman Primate Reaching with Multichannel Sensorimotor Cortex Electrophysiology: broadband for indy_20161207_02
<p>This dataset supplements <a href="https://doi.org/10.5281/zenodo.583331">https://doi.org/10.5281/zenodo.583331</a> .<br> <br> <strong>General description.</strong> These data consist of extracellular neural recordings ("broadband") from primate subject "Indy", session identifier "indy_20161207_02".</p> <p><strong>Filtering. </strong>The data are sampled at 24414.0625 Hz and are unfiltered, except for an anti-aliasing filter built-in to the recording amplifier: a 4th order low-pass with a roll-off of 24 dB per octave at 7.5 kHz, operating at the sampling rate.</p> <p><strong>File format.</strong> The data are contained in an HDF5 formatted file, organized according to the <a href="https://github.com/NeurodataWithoutBorders/specification">Neurodata Without Borders (NWB) version 1.0.6</a> specification.</p> <p><strong>Datasets. </strong>A few of the relevant dataset paths are listed here for convenience. In the below, <em>n</em> refers to the number of recording channels and <em>k</em> refers to the number of samples.</p> <ul> <li>"/acquisition/timeseries/broadband/data" - k x n <ul> <li>The broadband neural recordings.</li> </ul> </li> <li>"/acquisition/timeseries/broadband/data/conversion" (scalar attribute) <ul> <li>When multiplied by each sample converts the data into units of volts.</li> </ul> </li> <li>"/acquisition/timeseries/broadband/timestamps" - k x 1 <ul> <li>Timestamps for each sample, seconds.</li> </ul> </li> <li>"/general/extracellular_ephys/electrode_map" - n x 3 <ul> <li>The relative coordinates of each electrode contact (x, y, z), meters.</li> </ul> </li> </ul> <p>Please refer to the <a href="https://doi.org/10.5281/zenodo.583331">master dataset</a> for further information.</p>
Nonhuman Primate Reaching with Multichannel Sensorimotor Cortex Electrophysiology: broadband for indy_20161212_02
<p>This dataset supplements <a href="https://doi.org/10.5281/zenodo.583331">https://doi.org/10.5281/zenodo.583331</a> .<br> <br> <strong>General description.</strong> These data consist of extracellular neural recordings ("broadband") from primate subject "Indy", session identifier "indy_20161212_02".</p> <p><strong>Filtering. </strong>The data are sampled at 24414.0625 Hz and are unfiltered, except for an anti-aliasing filter built-in to the recording amplifier: a 4th order low-pass with a roll-off of 24 dB per octave at 7.5 kHz, operating at the sampling rate.</p> <p><strong>File format.</strong> The data are contained in an HDF5 formatted file, organized according to the <a href="https://github.com/NeurodataWithoutBorders/specification">Neurodata Without Borders (NWB) version 1.0.6</a> specification.</p> <p><strong>Datasets. </strong>A few of the relevant dataset paths are listed here for convenience. In the below, <em>n</em> refers to the number of recording channels and <em>k</em> refers to the number of samples.</p> <ul> <li>"/acquisition/timeseries/broadband/data" - k x n <ul> <li>The broadband neural recordings.</li> </ul> </li> <li>"/acquisition/timeseries/broadband/data/conversion" (scalar attribute) <ul> <li>When multiplied by each sample converts the data into units of volts.</li> </ul> </li> <li>"/acquisition/timeseries/broadband/timestamps" - k x 1 <ul> <li>Timestamps for each sample, seconds.</li> </ul> </li> <li>"/general/extracellular_ephys/electrode_map" - n x 3 <ul> <li>The relative coordinates of each electrode contact (x, y, z), meters.</li> </ul> </li> </ul> <p>Please refer to the <a href="https://doi.org/10.5281/zenodo.583331">master dataset</a> for further information.</p>
Nonhuman Primate Reaching with Multichannel Sensorimotor Cortex Electrophysiology: broadband for indy_20161206_02
<p>This dataset supplements <a href="https://doi.org/10.5281/zenodo.583331">https://doi.org/10.5281/zenodo.583331</a> .<br> <br> <strong>General description.</strong> These data consist of extracellular neural recordings ("broadband") from primate subject "Indy", session identifier "indy_20161206_02".</p> <p><strong>Filtering. </strong>The data are sampled at 24414.0625 Hz and are unfiltered, except for an anti-aliasing filter built-in to the recording amplifier: a 4th order low-pass with a roll-off of 24 dB per octave at 7.5 kHz, operating at the sampling rate.</p> <p><strong>File format.</strong> The data are contained in an HDF5 formatted file, organized according to the <a href="https://github.com/NeurodataWithoutBorders/specification">Neurodata Without Borders (NWB) version 1.0.6</a> specification.</p> <p><strong>Datasets. </strong>A few of the relevant dataset paths are listed here for convenience. In the below, <em>n</em> refers to the number of recording channels and <em>k</em> refers to the number of samples.</p> <ul> <li>"/acquisition/timeseries/broadband/data" - k x n <ul> <li>The broadband neural recordings.</li> </ul> </li> <li>"/acquisition/timeseries/broadband/data/conversion" (scalar attribute) <ul> <li>When multiplied by each sample converts the data into units of volts.</li> </ul> </li> <li>"/acquisition/timeseries/broadband/timestamps" - k x 1 <ul> <li>Timestamps for each sample, seconds.</li> </ul> </li> <li>"/general/extracellular_ephys/electrode_map" - n x 3 <ul> <li>The relative coordinates of each electrode contact (x, y, z), meters.</li> </ul> </li> </ul> <p>Please refer to the <a href="https://doi.org/10.5281/zenodo.583331">master dataset</a> for further information.</p>
Transcranial direct current stimulation (tDCS) over the left prefrontal cortex does not affect time-trial self-paced cycling performance: Evidence from oscillatory brain activity and power output.
<p>This research will shed new light into the bidirectional relationship between acute aerobic exercise, brain and cognition. This is based on the particular role of executive (cognitive) function during exercise. The rationale of our study is that stimulation of the prefrontal cortex that has been repeatedly associated with executive function, would facilitate or impair self-paced aerobic exercise. This would also affect cognitive performance immediately after exercise. We will use a modified flanker’s task as a form of assessing executive function (see below for further details). The flanker’s task implies two different stimuli, one congruent and one incongruent. Relative to “congruent” stimuli, these “incongruent” stimuli are usually accompanied by increased response times (RTs) and decreased accuracy. To stimulate the prefrontal cortex, we use transcranial direct-current stimulation (tDCS). tDCS is able to induce cortical changes by hyperpolarizing (anodal) or depolarizing (cathodal) neuron’s resting membrane potential.<br> Therefore, the hypotheses of this research are:<br> 1) Anodal stimulation (relative to sham and cathodal stimulation) will improve self-paced aerobic exercise and, consequently it will also improve subsequent cognitive performance.<br> 2) Cathodal stimulation (relative to sham and anodal stimulation) will impair self-paced aerobic exercise and subsequent cognitive performance.<br> </p>
Nonhuman Primate Reaching with Multichannel Sensorimotor Cortex Electrophysiology: broadband for indy_20161026_03
<p>This dataset supplements <a href="https://doi.org/10.5281/zenodo.583331">https://doi.org/10.5281/zenodo.583331</a> .<br> <br> <strong>General description.</strong> These data consist of extracellular neural recordings ("broadband") from primate subject "Indy", session identifier "indy_20161026_03".</p> <p><strong>Filtering. </strong>The data are sampled at 24414.0625 Hz and are unfiltered, except for an anti-aliasing filter built-in to the recording amplifier: a 4th order low-pass with a roll-off of 24 dB per octave at 7.5 kHz, operating at the sampling rate.</p> <p><strong>File format.</strong> The data are contained in an HDF5 formatted file, organized according to the <a href="https://github.com/NeurodataWithoutBorders/specification">Neurodata Without Borders (NWB) version 1.0.6</a> specification.</p> <p><strong>Datasets. </strong>A few of the relevant dataset paths are listed here for convenience. In the below, <em>n</em> refers to the number of recording channels and <em>k</em> refers to the number of samples.</p> <ul> <li>"/acquisition/timeseries/broadband/data" - k x n <ul> <li>The broadband neural recordings.</li> </ul> </li> <li>"/acquisition/timeseries/broadband/data/conversion" (scalar attribute) <ul> <li>When multiplied by each sample converts the data into units of volts.</li> </ul> </li> <li>"/acquisition/timeseries/broadband/timestamps" - k x 1 <ul> <li>Timestamps for each sample, seconds.</li> </ul> </li> <li>"/general/extracellular_ephys/electrode_map" - n x 3 <ul> <li>The relative coordinates of each electrode contact (x, y, z), meters.</li> </ul> </li> </ul> <p>Please refer to the <a href="https://doi.org/10.5281/zenodo.583331">master dataset</a> for further information.</p>
Nonhuman Primate Reaching with Multichannel Sensorimotor Cortex Electrophysiology: broadband for indy_20161027_03
<p>This dataset supplements <a href="https://doi.org/10.5281/zenodo.583331">https://doi.org/10.5281/zenodo.583331</a> .<br> <br> <strong>General description.</strong> These data consist of extracellular neural recordings ("broadband") from primate subject "Indy", session identifier "indy_20161027_03".</p> <p><strong>Filtering. </strong>The data are sampled at 24414.0625 Hz and are unfiltered, except for an anti-aliasing filter built-in to the recording amplifier: a 4th order low-pass with a roll-off of 24 dB per octave at 7.5 kHz, operating at the sampling rate.</p> <p><strong>File format.</strong> The data are contained in an HDF5 formatted file, organized according to the <a href="https://github.com/NeurodataWithoutBorders/specification">Neurodata Without Borders (NWB) version 1.0.6</a> specification.</p> <p><strong>Datasets. </strong>A few of the relevant dataset paths are listed here for convenience. In the below, <em>n</em> refers to the number of recording channels and <em>k</em> refers to the number of samples.</p> <ul> <li>"/acquisition/timeseries/broadband/data" - k x n <ul> <li>The broadband neural recordings.</li> </ul> </li> <li>"/acquisition/timeseries/broadband/data/conversion" (scalar attribute) <ul> <li>When multiplied by each sample converts the data into units of volts.</li> </ul> </li> <li>"/acquisition/timeseries/broadband/timestamps" - k x 1 <ul> <li>Timestamps for each sample, seconds.</li> </ul> </li> <li>"/general/extracellular_ephys/electrode_map" - n x 3 <ul> <li>The relative coordinates of each electrode contact (x, y, z), meters.</li> </ul> </li> </ul> <p>Please refer to the <a href="https://doi.org/10.5281/zenodo.583331">master dataset</a> for further information.</p>
Nonhuman Primate Reaching with Multichannel Sensorimotor Cortex Electrophysiology: broadband for indy_20161025_04
<p>This dataset supplements <a href="https://doi.org/10.5281/zenodo.583331">https://doi.org/10.5281/zenodo.583331</a> .<br> <br> <strong>General description.</strong> These data consist of extracellular neural recordings ("broadband") from primate subject "Indy", session identifier "indy_20161025_04".</p> <p><strong>Filtering. </strong>The data are sampled at 24414.0625 Hz and are unfiltered, except for an anti-aliasing filter built-in to the recording amplifier: a 4th order low-pass with a roll-off of 24 dB per octave at 7.5 kHz, operating at the sampling rate.</p> <p><strong>File format.</strong> The data are contained in an HDF5 formatted file, organized according to the <a href="https://github.com/NeurodataWithoutBorders/specification">Neurodata Without Borders (NWB) version 1.0.6</a> specification.</p> <p><strong>Datasets. </strong>A few of the relevant dataset paths are listed here for convenience. In the below, <em>n</em> refers to the number of recording channels and <em>k</em> refers to the number of samples.</p> <ul> <li>"/acquisition/timeseries/broadband/data" - k x n <ul> <li>The broadband neural recordings.</li> </ul> </li> <li>"/acquisition/timeseries/broadband/data/conversion" (scalar attribute) <ul> <li>When multiplied by each sample converts the data into units of volts.</li> </ul> </li> <li>"/acquisition/timeseries/broadband/timestamps" - k x 1 <ul> <li>Timestamps for each sample, seconds.</li> </ul> </li> <li>"/general/extracellular_ephys/electrode_map" - n x 3 <ul> <li>The relative coordinates of each electrode contact (x, y, z), meters.</li> </ul> </li> </ul> <p>Please refer to the <a href="https://doi.org/10.5281/zenodo.583331">master dataset</a> for further information.</p>
Nonhuman Primate Reaching with Multichannel Sensorimotor Cortex Electrophysiology: broadband for indy_20161024_03
<p>This dataset supplements <a href="https://doi.org/10.5281/zenodo.583331">https://doi.org/10.5281/zenodo.583331</a> .<br> <br> <strong>General description.</strong> These data consist of extracellular neural recordings ("broadband") from primate subject "Indy", session identifier "indy_20161024_03".</p> <p><strong>Filtering. </strong>The data are sampled at 24414.0625 Hz and are unfiltered, except for an anti-aliasing filter built-in to the recording amplifier: a 4th order low-pass with a roll-off of 24 dB per octave at 7.5 kHz, operating at the sampling rate.</p> <p><strong>File format.</strong> The data are contained in an HDF5 formatted file, organized according to the <a href="https://github.com/NeurodataWithoutBorders/specification">Neurodata Without Borders (NWB) version 1.0.6</a> specification.</p> <p><strong>Datasets. </strong>A few of the relevant dataset paths are listed here for convenience. In the below, <em>n</em> refers to the number of recording channels and <em>k</em> refers to the number of samples.</p> <ul> <li>"/acquisition/timeseries/broadband/data" - k x n <ul> <li>The broadband neural recordings.</li> </ul> </li> <li>"/acquisition/timeseries/broadband/data/conversion" (scalar attribute) <ul> <li>When multiplied by each sample converts the data into units of volts.</li> </ul> </li> <li>"/acquisition/timeseries/broadband/timestamps" - k x 1 <ul> <li>Timestamps for each sample, seconds.</li> </ul> </li> <li>"/general/extracellular_ephys/electrode_map" - n x 3 <ul> <li>The relative coordinates of each electrode contact (x, y, z), meters.</li> </ul> </li> </ul> <p>Please refer to the <a href="https://doi.org/10.5281/zenodo.583331">master dataset</a> for further information.</p>
Nonhuman Primate Reaching with Multichannel Sensorimotor Cortex Electrophysiology: broadband for indy_20161017_02
<p>This dataset supplements <a href="https://doi.org/10.5281/zenodo.583331">https://doi.org/10.5281/zenodo.583331</a> .<br> <br> <strong>General description.</strong> These data consist of extracellular neural recordings ("broadband") from primate subject "Indy", session identifier "indy_20161017_02".</p> <p><strong>Filtering. </strong>The data are sampled at 24414.0625 Hz and are unfiltered, except for an anti-aliasing filter built-in to the recording amplifier: a 4th order low-pass with a roll-off of 24 dB per octave at 7.5 kHz, operating at the sampling rate.</p> <p><strong>File format.</strong> The data are contained in an HDF5 formatted file, organized according to the <a href="https://github.com/NeurodataWithoutBorders/specification">Neurodata Without Borders (NWB) version 1.0.6</a> specification.</p> <p><strong>Datasets. </strong>A few of the relevant dataset paths are listed here for convenience. In the below, <em>n</em> refers to the number of recording channels and <em>k</em> refers to the number of samples.</p> <ul> <li>"/acquisition/timeseries/broadband/data" - k x n <ul> <li>The broadband neural recordings.</li> </ul> </li> <li>"/acquisition/timeseries/broadband/data/conversion" (scalar attribute) <ul> <li>When multiplied by each sample converts the data into units of volts.</li> </ul> </li> <li>"/acquisition/timeseries/broadband/timestamps" - k x 1 <ul> <li>Timestamps for each sample, seconds.</li> </ul> </li> <li>"/general/extracellular_ephys/electrode_map" - n x 3 <ul> <li>The relative coordinates of each electrode contact (x, y, z), meters.</li> </ul> </li> </ul> <p>Please refer to the <a href="https://doi.org/10.5281/zenodo.583331">master dataset</a> for further information.</p>
Nonhuman Primate Reaching with Multichannel Sensorimotor Cortex Electrophysiology: broadband for indy_20161014_04
<p>This dataset supplements <a href="https://doi.org/10.5281/zenodo.583331">https://doi.org/10.5281/zenodo.583331</a> .<br> <br> <strong>General description.</strong> These data consist of extracellular neural recordings ("broadband") from primate subject "Indy", session identifier "indy_20161014_04".</p> <p><strong>Filtering. </strong>The data are sampled at 24414.0625 Hz and are unfiltered, except for an anti-aliasing filter built-in to the recording amplifier: a 4th order low-pass with a roll-off of 24 dB per octave at 7.5 kHz, operating at the sampling rate.</p> <p><strong>File format.</strong> The data are contained in an HDF5 formatted file, organized according to the <a href="https://github.com/NeurodataWithoutBorders/specification">Neurodata Without Borders (NWB) version 1.0.6</a> specification.</p> <p><strong>Datasets. </strong>A few of the relevant dataset paths are listed here for convenience. In the below, <em>n</em> refers to the number of recording channels and <em>k</em> refers to the number of samples.</p> <ul> <li>"/acquisition/timeseries/broadband/data" - k x n <ul> <li>The broadband neural recordings.</li> </ul> </li> <li>"/acquisition/timeseries/broadband/data/conversion" (scalar attribute) <ul> <li>When multiplied by each sample converts the data into units of volts.</li> </ul> </li> <li>"/acquisition/timeseries/broadband/timestamps" - k x 1 <ul> <li>Timestamps for each sample, seconds.</li> </ul> </li> <li>"/general/extracellular_ephys/electrode_map" - n x 3 <ul> <li>The relative coordinates of each electrode contact (x, y, z), meters.</li> </ul> </li> </ul> <p>Please refer to the <a href="https://doi.org/10.5281/zenodo.583331">master dataset</a> for further information.</p>
Nonhuman Primate Reaching with Multichannel Sensorimotor Cortex Electrophysiology: broadband for indy_20161011_03
<p>This dataset supplements <a href="https://doi.org/10.5281/zenodo.583331">https://doi.org/10.5281/zenodo.583331</a> .<br> <br> <strong>General description.</strong> These data consist of extracellular neural recordings ("broadband") from primate subject "Indy", session identifier "indy_20161011_03".</p> <p><strong>Filtering. </strong>The data are sampled at 24414.0625 Hz and are unfiltered, except for an anti-aliasing filter built-in to the recording amplifier: a 4th order low-pass with a roll-off of 24 dB per octave at 7.5 kHz, operating at the sampling rate.</p> <p><strong>File format.</strong> The data are contained in an HDF5 formatted file, organized according to the <a href="https://github.com/NeurodataWithoutBorders/specification">Neurodata Without Borders (NWB) version 1.0.6</a> specification.</p> <p><strong>Datasets. </strong>A few of the relevant dataset paths are listed here for convenience. In the below, <em>n</em> refers to the number of recording channels and <em>k</em> refers to the number of samples.</p> <ul> <li>"/acquisition/timeseries/broadband/data" - k x n <ul> <li>The broadband neural recordings.</li> </ul> </li> <li>"/acquisition/timeseries/broadband/data/conversion" (scalar attribute) <ul> <li>When multiplied by each sample converts the data into units of volts.</li> </ul> </li> <li>"/acquisition/timeseries/broadband/timestamps" - k x 1 <ul> <li>Timestamps for each sample, seconds.</li> </ul> </li> <li>"/general/extracellular_ephys/electrode_map" - n x 3 <ul> <li>The relative coordinates of each electrode contact (x, y, z), meters.</li> </ul> </li> </ul> <p>Please refer to the <a href="https://doi.org/10.5281/zenodo.583331">master dataset</a> for further information.</p>
Nonhuman Primate Reaching with Multichannel Sensorimotor Cortex Electrophysiology: broadband for indy_20161013_03
<p>This dataset supplements <a href="https://doi.org/10.5281/zenodo.583331">https://doi.org/10.5281/zenodo.583331</a> .<br> <br> <strong>General description.</strong> These data consist of extracellular neural recordings ("broadband") from primate subject "Indy", session identifier "indy_20161013_03".</p> <p><strong>Filtering. </strong>The data are sampled at 24414.0625 Hz and are unfiltered, except for an anti-aliasing filter built-in to the recording amplifier: a 4th order low-pass with a roll-off of 24 dB per octave at 7.5 kHz, operating at the sampling rate.</p> <p><strong>File format.</strong> The data are contained in an HDF5 formatted file, organized according to the <a href="https://github.com/NeurodataWithoutBorders/specification">Neurodata Without Borders (NWB) version 1.0.6</a> specification.</p> <p><strong>Datasets. </strong>A few of the relevant dataset paths are listed here for convenience. In the below, <em>n</em> refers to the number of recording channels and <em>k</em> refers to the number of samples.</p> <ul> <li>"/acquisition/timeseries/broadband/data" - k x n <ul> <li>The broadband neural recordings.</li> </ul> </li> <li>"/acquisition/timeseries/broadband/data/conversion" (scalar attribute) <ul> <li>When multiplied by each sample converts the data into units of volts.</li> </ul> </li> <li>"/acquisition/timeseries/broadband/timestamps" - k x 1 <ul> <li>Timestamps for each sample, seconds.</li> </ul> </li> <li>"/general/extracellular_ephys/electrode_map" - n x 3 <ul> <li>The relative coordinates of each electrode contact (x, y, z), meters.</li> </ul> </li> </ul> <p>Please refer to the <a href="https://doi.org/10.5281/zenodo.583331">master dataset</a> for further information.</p>
Nonhuman Primate Reaching with Multichannel Sensorimotor Cortex Electrophysiology: broadband for indy_20161007_02
<p>This dataset supplements <a href="https://doi.org/10.5281/zenodo.583331">https://doi.org/10.5281/zenodo.583331</a> .<br> <br> <strong>General description.</strong> These data consist of extracellular neural recordings ("broadband") from primate subject "Indy", session identifier "indy_20161007_02".</p> <p><strong>Filtering. </strong>The data are sampled at 24414.0625 Hz and are unfiltered, except for an anti-aliasing filter built-in to the recording amplifier: a 4th order low-pass with a roll-off of 24 dB per octave at 7.5 kHz, operating at the sampling rate.</p> <p><strong>File format.</strong> The data are contained in an HDF5 formatted file, organized according to the <a href="https://github.com/NeurodataWithoutBorders/specification">Neurodata Without Borders (NWB) version 1.0.6</a> specification.</p> <p><strong>Datasets. </strong>A few of the relevant dataset paths are listed here for convenience. In the below, <em>n</em> refers to the number of recording channels and <em>k</em> refers to the number of samples.</p> <ul> <li>"/acquisition/timeseries/broadband/data" - k x n <ul> <li>The broadband neural recordings.</li> </ul> </li> <li>"/acquisition/timeseries/broadband/data/conversion" (scalar attribute) <ul> <li>When multiplied by each sample converts the data into units of volts.</li> </ul> </li> <li>"/acquisition/timeseries/broadband/timestamps" - k x 1 <ul> <li>Timestamps for each sample, seconds.</li> </ul> </li> <li>"/general/extracellular_ephys/electrode_map" - n x 3 <ul> <li>The relative coordinates of each electrode contact (x, y, z), meters.</li> </ul> </li> </ul> <p>Please refer to the <a href="https://doi.org/10.5281/zenodo.583331">master dataset</a> for further information.</p>
Nonhuman Primate Reaching with Multichannel Sensorimotor Cortex Electrophysiology: broadband for indy_20161006_02
<p>This dataset supplements <a href="https://doi.org/10.5281/zenodo.583331">https://doi.org/10.5281/zenodo.583331</a> .<br> <br> <strong>General description.</strong> These data consist of extracellular neural recordings ("broadband") from primate subject "Indy", session identifier "indy_20161006_02".</p> <p><strong>Filtering. </strong>The data are sampled at 24414.0625 Hz and are unfiltered, except for an anti-aliasing filter built-in to the recording amplifier: a 4th order low-pass with a roll-off of 24 dB per octave at 7.5 kHz, operating at the sampling rate.</p> <p><strong>File format.</strong> The data are contained in an HDF5 formatted file, organized according to the <a href="https://github.com/NeurodataWithoutBorders/specification">Neurodata Without Borders (NWB) version 1.0.6</a> specification.</p> <p><strong>Datasets. </strong>A few of the relevant dataset paths are listed here for convenience. In the below, <em>n</em> refers to the number of recording channels and <em>k</em> refers to the number of samples.</p> <ul> <li>"/acquisition/timeseries/broadband/data" - k x n <ul> <li>The broadband neural recordings.</li> </ul> </li> <li>"/acquisition/timeseries/broadband/data/conversion" (scalar attribute) <ul> <li>When multiplied by each sample converts the data into units of volts.</li> </ul> </li> <li>"/acquisition/timeseries/broadband/timestamps" - k x 1 <ul> <li>Timestamps for each sample, seconds.</li> </ul> </li> <li>"/general/extracellular_ephys/electrode_map" - n x 3 <ul> <li>The relative coordinates of each electrode contact (x, y, z), meters.</li> </ul> </li> </ul> <p>Please refer to the <a href="https://doi.org/10.5281/zenodo.583331">master dataset</a> for further information.</p>
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.