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137
datasets available to search
ShareScore release 0.7.1
Dataset results
137 results for “Domain specificity”
Pronounced specificity of the TET enzyme catalytic domain guides cellular function
GEO Series GSE199083. Mus musculus. 8 samples. Type: Methylation profiling by high throughput sequencing.
Male-specific Fruitless isoforms have different regulatory roles conferred by distinct zinc finger DNA binding domains
GEO Series GSE50515. Drosophila melanogaster. 39 samples. Type: Expression profiling by high throughput sequencing.
Allele-specific aberration of imprinted domain chromosome architecture associates with large offspring syndrome
GEO Series GSE197130. Bos indicus; Bos indicus x Bos taurus. 50 samples. Type: Other; Genome variation profiling by high throughput sequencing; Methylation profiling by high throughput sequencing.
Orientation-specific RAG activity in chromosomal loop domain contribute to Tcrd V(D)J recombination during T cell development
GEO Series GSE79892. Mus musculus. 31 samples. Type: Other.
Probing the regulatory effects of specific mutations in three major binding domains of the pleiotropic regulator CcpA of Bacillus subtilis
GEO Series GSE69575. Bacillus subtilis subsp. subtilis str. 168; Bacillus subtilis. 24 samples. Type: Expression profiling by array.
Dual specificity and target gene selection by the MADS domain protein FRUITFULL
GEO Series GSE194055. Arabidopsis thaliana. 12 samples. Type: Expression profiling by high throughput sequencing.
Specific 3-O-sulfated heparan sulfate domains regulate salivary gland basement membrane metabolism and epithelial differentiation [male]
GEO Series GSE235184. Mus musculus. 9 samples. Type: Expression profiling by high throughput sequencing.
DNA methylation and lncRNA expression control asynchronous DNA replication at specific imprinted gene domains [Capture Hi-C]
GEO Series GSE289022. Mus musculus. 4 samples. Type: Other.
DNA replication-timing boundaries separate stable chromosome domains with cell-type-specific functions
GEO Series GSE51334. Homo sapiens; Mus musculus. 993 samples. Type: Other.
Replacing C189 in the bZIP domain of Zta to S, T, V, and A changes DNA binding specificity to four types of double-stranded DNA (mCG)
GEO Series GSE108273. human gammaherpesvirus 4; synthetic construct. 20 samples. Type: Other.
Temporal and spatial domain-specific transcriptomic analysis of a vital reproductive meristem in Arabidopsis thaliana
GEO Series GSE74458. Arabidopsis thaliana. 30 samples. Type: Expression profiling by high throughput sequencing.
PGC methylome analysis revealed large, germline-specific mouse hypomethylated DNA domains with unique genomic and epigenomic features [Agilent 44Kx1 Array Expression]
GEO Series GSE39800. Mus musculus. 4 samples. Type: Expression profiling by array.
A SWI/SNF -specific Ig-like domain, SWIFT, is a transcription factor binding platform
GEO Series GSE310119. Homo sapiens. 231 samples. Type: Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by high throughput sequencing.
The BEN domain is a novel sequence-specific DNA binding domain conserved in neural transcriptional repressors
GEO Series GSE44178. Drosophila melanogaster. 10 samples. Type: Expression profiling by array; Genome binding/occupancy profiling by high throughput sequencing.
Usability Evaluation Process for Domain-Specific Languages - Documents and survey data
<p>Usability Evaluation Process for Domain-Specific Languages - Documents and survey data</p>
Data from: Quantifying post- laser ablation prostate therapy changes on MRI via a domain-specific biomechanical model: preliminary findings
Focal laser ablation destroys cancerous cells via thermal destruction of tissue by a laser. Heat is absorbed, causing thermal necrosis of the target region. It combines the aggressive benefits of radiation treatment (destroying cancer cells) without the harmful side effects (due to its precise localization). MRI is typically used pre-treatment to determine the targeted area, and post-treatment to determine efficacy by detecting necrotic tissue, or tumor recurrence. However, no system exists to quantitatively evaluate the post-treatment effects on the morphology and structure via MRI. To quantify these changes, the pre- and post-treatment MR images must first be spatially aligned. The goal is to quantify (a) laser-induced shape-based changes, and (b) changes in MRI parameters post-treatment. The shape-based changes may be correlated with treatment efficacy, and the quantitative effects of laser treatment over time is currently poorly understood. This work attempts to model changes in gland morphology following laser treatment due to (1) patient alignment, (2) changes due to surrounding organs such as the bladder and rectum, and (3) changes due to the treatment itself. To isolate the treatment-induced shape-based changes, the changes from (1) and (2) are first modeled and removed using a finite element model (FEM). A FEM models the physical properties of tissue. The use of a physical biomechanical model is important since a stated goal of this work is to determine the physical shape-based changes to the prostate from the treatment, and therefore only physical real deformations are to be allowed. A second FEM is then used to isolate the physical, shape-based, treatment-induced changes. We applied and evaluated our model in capturing the laser induced changes to the prostate morphology on eight patients with 3.0 Tesla, T2-weighted MRI, acquired approximately six months following treatment. Our results suggest the laser treatment causes a decrease in prostate volume, which appears to manifest predominantly at the site of ablation. After spatially aligning the images, changes to MRI intensity values are clearly visible at the site of ablation. Our results suggest that our new methodology is able to capture and quantify the degree of laser-induced changes to the prostate. The quantitative measurements reflecting of the deformation changes can be used to track treatment response over time.
SMWCloud: A Corpus of Domain-Specific Knowledge Graphs from Semantic MediaWikis
<p>Semantic wikis have become an increasingly popular means of collaboratively managing Knowledge Graphs. They are powered by platforms such as Semantic MediaWiki and Wikibase, both of which enable MediaWiki to store and publish structured data. While there are many semantic wikis currently in use, there has been little effort to collect and analyse their structured data, nor to make it available for the research community. This resource seeks to address this gap by systematically collecting structured data from an extensive corpus of Semantic-MediaWiki-powered portals and providing an in-depth analysis of the ontological diversity (and re-use) amongst these wikis using a variety of ontological metrics. Our resource aims to demonstrate that semantic wikis are a valuable and extensive part of Linked Open Data (LOD), and in fact may be considered an own active ``sub-cloud'' within the LOD ecosystem, which can provide useful insights into the evolution of small and medium-sized domain-specific Knowledge Graphs.</p>
Examining Effects of Domain Specific Episodic Future Thinking on Cannabis Use
ClinicalTrials.gov study NCT05324813. IPD Sharing: YES. Countries: 1. Publications: 0.
Generalized and Domain-Specific Episodic Thinking for Smoking Cessation
ClinicalTrials.gov study NCT07158749. IPD Sharing: YES. Countries: 1. Publications: 0.
Domain-general and Domain-specific Contributions to the Development of Numerical Cognition
ClinicalTrials.gov study NCT06658392. IPD Sharing: Not stated. Countries: 1. Publications: 0.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.