Find research datasets worth reusing
Search datasets from major research repositories and use ShareScore to quickly assess how well each record supports discovery, access, and reuse.
581
datasets available to search
ShareScore release 0.9.0
Dataset results
581 results for “Eosinophils”
Efficacy of Dupilumab on Facilitated Food Introduction in Eosinophilic Esophagitis
ClinicalTrials.gov study NCT05247866. IPD Sharing: YES. Countries: 1. Publications: 6.
Dose-Ranging Study of Oral Viscous Budesonide in Pediatrics With Eosinophilic Esophagitis
ClinicalTrials.gov study NCT00762073. IPD Sharing: Not stated. Countries: 1. Publications: 2.
A Study of AK002 in Patients With Eosinophilic Gastritis and/or Eosinophilic Gastroenteritis
ClinicalTrials.gov study NCT03496571. IPD Sharing: NO. Countries: 1. Publications: 2.
A Trial of Montelukast for Maintenance Therapy of Eosinophilic Esophagitis in Children
ClinicalTrials.gov study NCT01458418. IPD Sharing: Not stated. Countries: 1. Publications: 17.
Budesonide Versus Fluticasone for Treatment of Eosinophilic Esophagitis
ClinicalTrials.gov study NCT02019758. IPD Sharing: NO. Countries: 1. Publications: 3.
Study of Reslizumab in Participants With Uncontrolled Asthma and Elevated Blood Eosinophils
ClinicalTrials.gov study NCT02452190. IPD Sharing: Not stated. Countries: 21. Publications: 1.
Effect of Elemental Diet on Adult Patients With Eosinophilic Gastroenteritis
ClinicalTrials.gov study NCT03320369. IPD Sharing: Not stated. Countries: 1. Publications: 1.
A Study to Evaluate the Efficacy and Safety of Reslizumab (0.3 or 3.0 mg/kg) as Treatment for Patients (12-75 Years of Age) With Eosinophilic Asthma
ClinicalTrials.gov study NCT01270464. IPD Sharing: Not stated. Countries: 13. Publications: 1.
Histological and TEM data: A major ecological niche of eosinophils in evolving Schistosoma granulomas challenges the eosinophil view as “helminth killer” cells
Open the record for dataset details and reuse information.
Eosinophil-derived neurotoxin (EDN): a biologically and analytically attractive asthma biomarker
<p>There is a growing body of evidence for the utility of eosinophil-derived neurotoxin (EDN) as a biomarker in asthma, including association with eosinophilic airway inflammation, assessment of disease severity and potential for predicting pathogenic risks, including exacerbations. However, to interpret any biomarker data with confidence, it is first important to understand the preanalytical factors and biological variation that may affect its reliable measurement and results interpretation. In this study we defined the healthy serum EDN reference range for men and women as 1.98 to 26.10 ng/mL, with no significant gender differences. Smoking did not impact the mean EDN levels and no circadian rhythm was identified for EDN, unlike blood eosinophils (EOS) where levels peaked at 00:00h. EDN expression in different cell types was investigated and shown to occur primarily in eosinophils, indicating they are likely to be the main cellular repository for EDN. We also confirm that the quantification of serum EDN is not influenced by the type of storage tube used, and it is stable at ambient temperature or when refrigerated for at least 7 days and for up to one year when frozen at -20°C or -80°C. In summary, EDN is a stable biomarker that may prove useful in precision medicine approaches by enabling the identification of a subpopulation of asthma patients with activated eosinophils and a more severe form of the disease. </p>
Active eosinophils regulate host defence and immune responses in colitis
<p>This repository contains processed R objects generated and used for this publication. </p><p>The code is available at: <a href="https://github.com/Moors-Code/Eosinophils_scRNASeq">https://github.com/Moors-Code/Eosinophils_scRNASeq</a>.</p><p>The publication can be accessed from here: <a href="https://www.nature.com/articles/s41586-022-05628-7">https://www.nature.com/articles/s41586-022-05628-7</a></p><p>The scRNAseq raw datasets are available here: <a href="https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE182001">https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE182001</a>.</p>
eosinophilic-esophagitis-singlecell_2022
<p>Analysis of eosinophilic esophagitis</p>
Treatment Efficacy of Systemic Corticosteroids in AECOPD Patients With Higher Blood Eosinophil Levels
ClinicalTrials.gov study NCT05059873. IPD Sharing: YES. Countries: 1. Publications: 9.
Rituximab in Eosinophilic Granulomatosis With Polyangiitis
ClinicalTrials.gov study NCT02807103. IPD Sharing: NO. Countries: 1. Publications: 1.
Budesonide Orodispersible Tablet vs. Placebo in Active Eosinophilic Esophagitis
ClinicalTrials.gov study NCT02434029. IPD Sharing: NO. Countries: 1. Publications: 2.
The Use of Fractionated Exhaled Nitric Oxide in the Diagnosis and Assessment of Disease Activity of Eosinophilic Esophagitis (Validation Phase)
ClinicalTrials.gov study NCT04941742. IPD Sharing: NO. Countries: 1. Publications: 1.
Eosinophil β1 Integrin Activation as a Biomarker for Eosinophilic Esophagitis
ClinicalTrials.gov study NCT02775045. IPD Sharing: YES. Countries: 1. Publications: 1.
Investigating the Effect of Obesity on Eosinophil Recruitment in Human Adipose Tissue
ClinicalTrials.gov study NCT04234295. IPD Sharing: NO. Countries: 1. Publications: 1.
A Study to Assess the Effect of Dexpramipexole in Adolescents and Adults With Eosinophilic Asthma
ClinicalTrials.gov study NCT05748600. IPD Sharing: NO. Countries: 18. Publications: 0.
Study of the Steroid Sparing Effect of Xolair (Omalizumab) in Patients With Persistent Eosinophilic Bronchitis
ClinicalTrials.gov study NCT02049294. IPD Sharing: UNDECIDED. Countries: 1. Publications: 1.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.