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580 results for “Eradication”

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ClinicalTrials.gov36/100

Research In Viral Eradication of HIV Reservoirs

ClinicalTrials.gov study NCT02336074. IPD Sharing: Not stated. Countries: 1. Publications: 42.

restrictedIPD-UNDECIDEDFeb 2026View details →
ClinicalTrials.gov36/100

Project CLEAR - Changing Lives by Eradicating Antibiotic Resistance

ClinicalTrials.gov study NCT01209234. IPD Sharing: Not stated. Countries: 1. Publications: 4.

restrictedIPD-UNDECIDEDFeb 2026View details →
ClinicalTrials.gov36/100

Compare Sequential and Quadruple Therapy for the Eradication of Helicobacter Pylori in Korea

ClinicalTrials.gov study NCT02159976. IPD Sharing: Not stated. Countries: 1. Publications: 1.

restrictedIPD-UNDECIDEDFeb 2026View details →
ClinicalTrials.gov36/100

Interventional Cryotherapy for the Eradication of Benign Airway Disease ("ICE the BAD")

ClinicalTrials.gov study NCT00747461. IPD Sharing: Not stated. Countries: 1. Publications: 9.

restrictedIPD-UNDECIDEDFeb 2026View details →
ClinicalTrials.gov36/100

Rifaximin Associated With Classic Triple Therapy for the Eradication of Helicobacter Pylori Infection

ClinicalTrials.gov study NCT03124199. IPD Sharing: UNDECIDED. Countries: 1. Publications: 20.

restrictedIPD-UNDECIDEDFeb 2026View details →
dryad36/100

Cost-effective portfolio allocation across quarantine, surveillance and eradication using info-gap theory

Open the record for dataset details and reuse information.

publicJul 2024View details →
dryad36/100

The effect of polyphenol compounds on Helicobacter pylori eradication: a systematic review with meta-analysis

Open the record for dataset details and reuse information.

publicDec 2022View details →
dryad36/100

Data from: Act for the best, prepare for the worst: Defining strategic mesopredator management triggers that safeguard apex predator eradication benefits

Open the record for dataset details and reuse information.

publicJan 2025View details →
dryad36/100

Data from: Can a mate-finding Allee effect be elicited to help eradicate invasive mammals?

Open the record for dataset details and reuse information.

publicDec 2025View details →
dryad32/100

Impacts of rodent eradication on seed predation and plant community biomass on a tropical atoll

<p>Invasive rodent eradications are frequently undertaken to curb island biodiversity loss. However, the breadth of rodents' ecological impact, even after eradication, is not always fully recognized. For example, the most widespread invasive rodent, the black rat (<i>Rattus rattus</i>),<i> </i>while omnivorous,<i> </i>eats predominantly seeds and fruit. Yet, the effects of seed predation release after eradication on plant communities and ecological functions are not well understood, posing a gap for island restoration. We examined the role of seed predation release following black rat eradication in changes to tree composition and above-ground biomass across an islet network (Palmyra Atoll) in the Central Pacific. We conducted repeated surveys of seed, juvenile, and adult tree biomass and survival in permanent vegetation plots before and after the eradication of rats. We observed a 95% reduction in seed predation for an introduced, previously cultivated tree population (<i>Cocos nucifera</i>). Juvenile tree biomass of all species increased 14-fold, with <i>C. nucifera </i>increasing the most, suggesting that eradication increased this tree's competitive advantage. Indeed, based on stage-structured demographic models, rat eradication led to a 10% increase in <i>C. nucifera </i>population growth rate. The effect of invasive rodent seed predation varies considerably among the plant species in a community and can shift competitive dynamics, sometimes in favor of invasive plants. These bottom-up effects should be considered in evaluating the costs and benefits of eradication.  Documenting the variation in invasive rodent diet items, along with long-term surveys, can help prioritize island eradications where restoration is most likely to be successful.  </p>

opencc-zeroAug 2020View details →
zenodo32/100

Supplementary material 4 from: Smart AS, Tingley R, Phillips BL (2020) Estimating the benefit of quarantine: eradicating invasive cane toads from islands. NeoBiota 60: 117-136. https://doi.org/10.3897/neobiota.60.34941

Figure S3. Posterior distributions of the detection probabilities of cane toads on Horan and Indian Islands

opencc-zeroOct 2020View details →
zenodo32/100

Supplementary material 2 from: Smart AS, Tingley R, Phillips BL (2020) Estimating the benefit of quarantine: eradicating invasive cane toads from islands. NeoBiota 60: 117-136. https://doi.org/10.3897/neobiota.60.34941

Figure S1. Estimated density of cane toads on each island using density calculated per km of shoreline, and per km2 of landmass

opencc-zeroOct 2020View details →
dryad32/100

Data from: Finding the best management policy to eradicate invasive species from spatial ecological networks with simultaneous actions

1. Spatial management of invasive species is more likely to be successful when multiple locations are treated simultaneously. However, selecting the best locations to act is difficult due to the many options available at any time. 2. We design a near-optimal policy for applying multiple actions simultaneously for faster invasive species control within a network. Our method uses a recent optimisation tool, the Graph-based Markov decision process (GMDP). Since the policy can be difficult to interpret, we extracted a simpler policy using classification trees. We applied our approach to the eradication of invasive mosquitofish (Gambusia holbrooki) from the habitat of the red-finned blue-eye (Scaturiginichthys vermeilipinnis), a critically endangered fish with a global population that is restricted to seven artesian springs in Queensland, Australia. 3. The policy returned by the GMDP was to manage springs occupied by mosquitofish and their connected neighbours, unless the neighbours were occupied by red-finned blue-eyes. 4. Simultaneous management resulted in rapid declines in simulated mosquitofish occupancy even if eradication effectiveness was low; however the cost of simultaneous eradication was high and sustained eradication effort was necessary to maintain low mosquitofish occupancy. 5. Synthesis and applications. Our paper finds a near-optimal, multi-action control policy to remove an invasive species from a multi-species spatial network. We introduce the Graph-based Markov decision process (GMDP) and apply it to a real case study – eradication of invasive mosquitofish from the habitat of the red-finned blue-eye. We find that the GMDP can generate policies for networks with extremely large state spaces, however it works best when nodes have fewer than five neighbours. We conclude that simultaneous eradications are effective for rapid control of invasive species; however, managers should consider the cost and time required for an effective eradication program.

opencc-zeroDec 2016View details →
dryad32/100

Data from: Successful eradication of a suburban Pallas's squirrel Callosciurus erythraeus (Pallas 1779) (Rodentia, Sciuridae) population in Flanders (northern Belgium)

Despite a growing catalogue of eradication projects, documented successful vertebrate eradications on the mainland remain scarce. Reporting on successful campaigns is crucial to counter pessimism on ambitious programmes to tackle invasive species and to allow conservation practitioners, wildlife managers and scientist to learn from previous experience. Moreover, there is a need for basic information on the effectiveness of control methods and management strategies that can be used. In this note we report on a successful low-tech eradication campaign of a local population of Pallas's squirrel Callosciurus erythraeus, a species of tree squirrel with documented ecological and socio-economic impacts in its invasive range. The population was eradicated from a suburban park of about 15 ha using baited mesh wire life traps, in five consecutive capture campaigns between October 2005 and January 2011. Using maximum likelihood estimation from catch-effort data we calculated initial densities in the park at 3 squirrels ha−1. Although control started quickly and the extent of the invasion was limited, the campaign took over 5 years and required an estimated investment of over €200,000 including 1.5 years of post-eradication surveying. We provide basic data on the methods used to eradicate this invasive rodent. Critical success factors and possible improvements with respect to the specific context of this case are discussed. Adding this species to the list of species of EU concern currently under development could provide incentive to minimise impact of this tree squirrel at the continental scale.

opencc-zeroDec 2014View details →
dryad32/100

Data from: Rat eradication and the resistance and resilience of passerine bird assemblages in the Falkland Islands

Norway rats (Rattus norvegicus) were introduced to the Falkland Islands and are detrimental to native passerines. Rat eradication programs are being used to help protect the avifauna. The present study assesses the effectiveness of eradication programs while using this conservation practice as a natural experiment to explore the ecological resistance, resilience, and homeostasis of bird communities. We conducted bird surveys on 230 islands: 85 in the presence of rats, 108 that were historically free of rats, and 37 from which rats had been eradicated. Bird detection data were used to build occupancy models for each species and estimate species-area relationships. Count data were used to estimate relative abundance and community structure. Islands with invasive rats had reduced species richness of passerines and a different community structure than islands on which rats were historically absent. Although the species richness of native passerines was remarkably similar on eradicated and historically rat-free islands, community structure on eradicated islands was more similar to that of rat-infested islands than to historically rat-free islands. The results suggest that in the Falkland Islands, species richness of passerines is not resistant to invasive rats, but seems to be resilient following their removal. In contrast, community structure seems to be neither resistant nor resilient. From a conservation perspective, rat eradication programs in the Falkland Islands appear to be effective at restoring native species richness, but they are not necessarily beneficial for species of conservation concern. For species that do not recolonize, translocations following eradications may be necessary.

opencc-zeroDec 2013View details →
dryad32/100

Data from: eDNA surveys to detect species at very low densities: a case study of European carp eradication in Tasmania, Australia

1. Eradications of invasive species are usually expensive and difficult to conduct. Knowing when to declare an eradication successful requires distinguishing between failed detection of the target species due to imperfect sensitivity of the detection method and true species absence. This is difficult because the sensitivities of many detection methods are unknown. 2. Environmental DNA (eDNA) methods can be used to detect species by analysing DNA present in environmental samples. eDNA has been promoted as a particularly sensitive and cost-effective way to detect species at low densities and, importantly, the sensitivity of eDNA surveys can be quantified. Nevertheless, the effort and costs involved in detecting species at extremely low densities, such as required during eradication, have not been previously calculated. 3. We evaluated the sensitivity of eDNA surveys in detecting the invasive European carp, Cyprinus carpio, in two lakes in Tasmania, Australia, one in which carp have been eradicated and a second in which carp are currently being eradicated. We determined the sampling effort and associated cost required to detect the species at very low density in these lakes. 4. While our eDNA survey detected the current low density carp population present in in Lake Sorell, we show that an exponential increase in sampling effort and associated cost will be required to confidently detect the species as the population declines. Similarly, while our eDNA survey corroborated the species absence from Lake Crescent, our detection confidence was low. We quantify the survey effort and financial investment required to confidently establish eradication success in Lake Crescent. Synthesis and applications: 5. Estimating the eDNA survey effort and cost required to detect species at a given density will enable practitioners to make informed decisions on the feasibility of implementing such surveys. Quantifying the sensitivity of eDNA surveys will also inform the confidence practitioners should place in the results of eDNA detection surveys to ensure appropriate management actions are implemented and provide a suitable stopping point at which to confidently declare eradication success.09-Jul-2019

opencc-zeroSep 2019View details →
dryad32/100

Data from: Resolving patterns of population genetic and phylogeographic structure to inform control and eradication initiatives for brown rats Rattus norvegicus on South Georgia

The control and eradication of invasive species is a common management strategy to protect or restore native biodiversity. On South Georgia in the Southern Ocean, the brown rat Rattus norvegicus was brought onto the island with the onset of whaling and sealing activity in the 1800s and has had a significant detrimental impact on key bird species of conservation concern. Efforts to eradicate rats from South Georgia using poisoned bait are ongoing. Despite the South Georgia rat eradication programme being the geographically largest and most ambitious eradication initiative to date, its success is facilitated by the potential that rat populations are effectively isolated by glacial barriers. This allows for localized eradication effort at manageable scales, leading to sequential eradication of individual populations with minimal risk of incursion from neighbouring areas. Here, we use the levels of population genetic divergence estimated from 299 single nucleotide polymorphism (SNP) loci and DNA sequence variation across 993 base pairs of the mitochondrial DNA cytochrome B locus to examine whether rat populations from nine glacially isolated areas on South Georgia are genetically distinct and so can be treated as independent eradication units. Bayesian clustering of individuals based on SNP similarity identified seven different genetic groups, which were confirmed using analyses based on pairwise genetic distance estimates and ordination of individuals using principal coordinate analysis. From a management perspective, these seven groups represent individual targets in baiting operations. Two mtDNA haplotypes were resolved across South Georgia, with a distinct geographical separation between the north-western and south-eastern populations. Approximate Bayesian computation (ABC) was used to identify that this divergence was a consequence of two separate historical colonization events. Synthesis and applications. We illustrate that molecular markers are a valuable tool in species management and pest eradication given that the spatial distribution of genetic diversity can: (i) identify demographically and genetically independent populations on which local eradication effort can be focussed, (ii) distinguish between incomplete eradication and immigration in situations where individuals remain after eradication has been attempted and (iii) identify the source of migrants when dispersal occurs over large spatial scales.

opencc-zeroDec 2014View details →
zenodo32/100

Distribution. Sub-Saharan Africa; virtually eradicated from W Africa, and greatly reduced in C and NE Africa. The largest populations exist in Botswana, Tanzania, and Zimbabwe, which account for approximately half of the estimated number of African Wild Dogs remaining in the wild. Other populations occur in Central African Republic, Ethiopia, Kenya, Mozambique, Namibia, South Africa, Sudan, and Zambia. Potential small populations (less than 100 individuals) may exist in Cameroon, Chad, Senegal, and Somalia. in Canidae

Distribution. Sub-Saharan Africa; virtually eradicated from W Africa, and greatly reduced in C and NE Africa. The largest populations exist in Botswana, Tanzania, and Zimbabwe, which account for approximately half of the estimated number of African Wild Dogs remaining in the wild. Other populations occur in Central African Republic, Ethiopia, Kenya, Mozambique, Namibia, South Africa, Sudan, and Zambia. Potential small populations (less than 100 individuals) may exist in Cameroon, Chad, Senegal, and Somalia.

opennotspecifiedJan 2009View details →
zenodo32/100

Distribution. Sub-Saharan Africa; virtually eradicated from W Africa, and greatly reduced in C and NE Africa. The largest populations exist in Botswana, Tanzania, and Zimbabwe, which account for approximately half of the estimated number of African Wild Dogs remaining in the wild. Other populations occur in Central African Republic, Ethiopia, Kenya, Mozambique, Namibia, South Africa, Sudan, and Zambia. Potential small populations (less than 100 individuals) may exist in Cameroon, Chad, Senegal, and Somalia. in Canidae

Distribution. Sub-Saharan Africa; virtually eradicated from W Africa, and greatly reduced in C and NE Africa. The largest populations exist in Botswana, Tanzania, and Zimbabwe, which account for approximately half of the estimated number of African Wild Dogs remaining in the wild. Other populations occur in Central African Republic, Ethiopia, Kenya, Mozambique, Namibia, South Africa, Sudan, and Zambia. Potential small populations (less than 100 individuals) may exist in Cameroon, Chad, Senegal, and Somalia.

opennotspecifiedJan 2009View details →
zenodo32/100

Saccharomyces boulardii in addition to antofloxacin-based bismuth quadruple therapy for Helicobacter pylori eradication

<p><em>Hpylori</em> is a gram-negative bacterium colonized in gastric mucosa. Currently, the infection rate of <em>H. pylori</em> in China is about 50%,&nbsp;which is not only closely related to a variety of digestive system diseases, but also induces a series of immune responses to other systems.</p>

opencc-by-4.0Apr 2022View details →

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Allen Brain Atlas

Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.

allen-brain-atlas
neuroscienceopenDocumentation, web resources, and API references are available online.
Last verified 2026-04-30Open record

Annotated Behaviour and Observability Dataset (ABODe)

ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.

abode-home-cage
behavioral-neuroscienceopenThe DataShare record exposes download links for annotations, documentation, license text, and the zipped per-snippet data directory.
Last verified 2026-04-30Open record

DANDI Archive for NWB datasets

DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.

dandi-nwb
electrophysiologyopenPublished Dandiset metadata and archive endpoints are available through the production DANDI API.
Last verified 2026-04-30Open record

International Brain Laboratory public data

The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.

ibl
behavioral-neuroscienceopenPublic sessions can be searched and loaded from the IBL public data server through ONE.
Last verified 2026-04-29Open record

OpenNeuro

OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.

openneuro
neuroscienceopenPublished datasets are available on demand over the internet.
Last verified 2026-04-29Open record

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