Find research datasets worth reusing
Search datasets from major research repositories and use ShareScore to quickly assess how well each record supports discovery, access, and reuse.
69
datasets available to search
ShareScore release 0.9.0
Dataset results
69 results for “Growth plasticity”
Functional plasticity and reversible growth behavior of patients’ acute myeloid leukemia stem cells growing in mice
GEO Series GSE141627. Homo sapiens. 24 samples. Type: Expression profiling by high throughput sequencing.
Data from: Plasticity in growth of farmed and wild Atlantic salmon: is the increased growth rate of farmed salmon caused by evolutionary adaptations to the commercial diet?
Open the record for dataset details and reuse information.
MicroRNA156 conditions auxin sensitivity to enable growth plasticity in response to environmental changes in Arabidopsis (RNA-Seq)
GEO Series GSE216360. Arabidopsis thaliana. 30 samples. Type: Expression profiling by high throughput sequencing.
MicroRNA156 conditions auxin sensitivity to enable growth plasticity in response to environmental changes in Arabidopsis
GEO Series GSE216362. Arabidopsis thaliana. 48 samples. Type: Expression profiling by high throughput sequencing; Non-coding RNA profiling by high throughput sequencing.
MicroRNA156 conditions auxin sensitivity to enable growth plasticity in response to environmental changes in Arabidopsis (miRNA-Seq)
GEO Series GSE216361. Arabidopsis thaliana. 18 samples. Type: Non-coding RNA profiling by high throughput sequencing.
The SIRT6-TDO2/KYNA-mTOR Axis Mediates Synaptic Plasticity and Cognitive Impairments in Fetal Growth Restriction Offspring
GEO Series GSE298372. Mus musculus. 8 samples. Type: Expression profiling by high throughput sequencing.
Ecdysone-mediated intestinal growth contributes to microbiota-driven developmental plasticity under malnutrition
GEO Series GSE310159. Drosophila melanogaster. 20 samples. Type: Expression profiling by high throughput sequencing.
Interdependent nutrient availability and steroid hormone signals facilitate root growth plasticity
GEO Series GSE114250. Arabidopsis thaliana. 8 samples. Type: Expression profiling by high throughput sequencing.
Growth differentiation factor 1-induced tumour plasticity provides a therapeutic window for immunotherapy in Hepatocellular Carcinoma
<p>Tumour lineage plasticity is an emerging hallmark of aggressive tumours. Tumour cells usually hijack developmental signaling pathways to gain cellular plasticity and evade therapeutic targeting. In the present study, the secreted protein growth and differentiation factor 1 (GDF1) was found to be closely associated with poor tumour differentiation. Overexpression of GDF1 suppressed cell proliferation but strongly enhanced tumour dissemination and metastasis. Ectopic expression of GDF1 induced the dedifferentiation of hepatocellular carcinoma (HCC) cells into their ancestral lineages and reactivated a broad panel of cancer testis antigens (CTAs), which further stimulated the immunogenicity of HCC cells to immune-based therapies. Mechanistic studies revealed that GDF1 functioned through the Anaplastic lymphoma kinase 7 (ALK7)-Mothers against decapentaplegic homolog 2/3 (SMAD2/3) signaling cascade and suppressed the epigenetic regulator Lysine specific demethylase 1 (LSD1) to boost CTA expression. GDF1-induced tumour lineage plasticity might be an Achilles heel for HCC immunotherapy. Inhibition of LSD1 based on GDF1 biomarker prescreening might widen the therapeutic window for immune checkpoint inhibitors in the clinic.</p>
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.